| Project/Area Number |
09470431
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
補綴理工系歯学
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
KIKUCHI Masahiko Hospital of Dentistry, Tohoku University, Lecturer, 歯学部・附属病院, 講師 (60195211)
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Makoto School of Dentistry, Tohoku University, Professor, 歯学部, 教授 (80091768)
HATTORI Yoshinori School of Dentistry, Tohoku University, Assistant Professor, 歯学部, 助手 (40238035)
ITOH Masatoshi Cyclotron RI Center, Tohoku University, Professor, サイクロトロンRIセンター, 教授 (00125501)
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| Project Period (FY) |
1997 – 1999
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| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1999: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1998: ¥1,200,000 (Direct Cost: ¥1,200,000)
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| Keywords | Masticatory dysfunction / Elderly patients / Removable dentures / Position CT / PET / Cerebral function / Masticatory muscle activity / Tongue muscle activity / PET |
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| Research Abstract |
Positron Emission Tomography (PET) with 18F-fluoro-D-deoxy glucose (FDG) was performed in healthy volunteers in order to investigate activities of the brain and the skeletal muscles in relation to masticatory function during gum chewing. As a result, it was found that activities of the masseter, temporal, medial pterygoid, lateral pterygoid, and tongue muscles could be simultaneously measured and quantified. PET images of the brain during gum chewing were also analyzed using SPM96 according to Friston et al. To clarify the characteristics of the brain activities. The primary sensorimotor areas, the premotor areas and the cerebellum were highly and bilaterally activated during arbitrary chewing while those activities were different in the left and right sides of the brain during the right side chewing. There were statistically significant differences in the brain activities during arbitrary chewing and the right side chewing. The activity of the right primary sensorimotor areas showed significantly higher during arbitrary chewing compared to the right side chewing. When the brain activities during the right side chewing was compared to those during arbitrary chewing, the left thalamus and mid brain, and the right putamen and cerebellum showed significantly higher activities. Thus it was appear that the brain activities differed depending on the chewing manner and this suggests that use of removable dentures also affect the brain activities.
On the other hand, a force transducer was developed to measure denture retention that was one of the evaluating factors for removable dentures. The transducer was proved to be useful when it was applied to the measurement of retention force for an experimental palatal plate in 10 subjects. The average retention force and the standard deviation ranged 0.71 to 1.00 N and 0.16 to 0.61, respectively. Whereas the retention forces showed wide variations between subjects, reproducibility of the measurement was acceptable.
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