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Fundamental Study for the Non-Invasive Laser Coagulation Method

Research Project

Project/Area Number 09555070
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section展開研究
Research Field Thermal engineering
Research InstitutionThe University of Tokyo

Principal Investigator

SHOJI Masahiro  The University of Tokyo, Dept.Mech. Eng., School of Eng., Professor, 大学院・工学系研究科, 教授 (00011130)

Co-Investigator(Kenkyū-buntansha) FUKUYO Tsuneo  Shinko Koki Ltd., Head manager, (研究職)取締役
HASHIMOTO Daijyo  Saitama Medical University, Dept.of Surgery, Professor, 教授
YOKOYA Sadao  The University of Tokyo, Dept.Mech. Eng., School of Eng., Research assistant, 大学院・工学系研究科, 助手 (00010869)
KOBAYASHI Tomio  Fuji Syashin Koki Ltd., manager, 技術企画室, (研究職)課長
小林 富士夫  富士写真光機, 技術企画室, 課長(研究職)
Project Period (FY) 1997 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥12,600,000 (Direct Cost: ¥12,600,000)
Fiscal Year 1999: ¥2,400,000 (Direct Cost: ¥2,400,000)
Fiscal Year 1998: ¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 1997: ¥7,300,000 (Direct Cost: ¥7,300,000)
KeywordsSurgery using Laser / Non-invasive surgery / Surface cooling / Laser coagulation / Laser heating / レーザ加熱 / 焼灼凝固 / 胃治療 / 医療福祉 / 低侵襲治療法 / 表面冷却法
Research Abstract

A serial research from the fundamental to application has been conducted for developing novel method of non-invasive laser coagulation method. In the first experiment, absorption and transparency of laser in tissues and also thermal properties such as heat conductivity and diffusivity are measured for understanding and modeling the laser coagulation. The measurement was made for meats and tissues of the pig as the test material. To confirm the possibility of the present idea of coagulation, theoretical analysis of the temperature distribution in tissues when the laser irradiates and the surface of tissues is cooled by cold water. After the theoretical analysis, experiment of laser irradiation by employing meats as the test material was carried out and compared with the analytical results. In the experiments, water temperature, water flow rate, laser strength and laser irradiation time were changed to investigate the effects for the tissue coagulation. The theoretical and experimental results agree well each other. At the next stage, a prototype handy coagulation devise was designed and produced for the experiment of application. It is found that this device can apply well to the coagulation of meats. So we proceeded to the animal tests. Namely, at the last stage of the research, animal tests were conducted with an aim to apply the present method to the coagulation of stomach of the pig. The changes of the before and after laser irradiation were investigated in detail, and the size of the region of coagulated tissues was measured and the relation of the size to the experimental parameters such as laser power and irradiation time was made clear. With an aim to accumulate sufficient data and confirm the applicability of the present method, the animal tests are still conducting.

Report

(4 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • 1997 Annual Research Report
  • Research Products

    (19 results)

All Other

All Publications (19 results)

  • [Publications] 前間篤,橋本大定,横谷定雄,庄司正弘,幕内雅敏: "消化管奨膜側からの照射による新しいレーザー治療"第20回日本レーザ医学会大会講演論文集. 77 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 前間篤,橋本大定,庄司正弘,横谷定雄,幕内雅敏: "表面温度制御法を用いた新しいレーザー治療法の開発-消化管に対する基礎研究-"第19回日本レーザ医学会大会講演論文集. 79 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 幕内雅敏,橋本大定,庄司正弘,横谷定雄,前間篤,渡辺誠,福留寛樹: "レーザ加熱治療法開発の基礎研究-組織の透過率の測定と動物実験-"第7回日本コンピュータ外科学会大会講演論文集. 125-126 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 前間篤,橋本大定,幕内雅敏,庄司正弘,横谷定雄,渡辺誠,福留寛樹: "レーザ加熱治療法開発の基礎研究"第35回日本伝熱シンポジウム講演論文集. 3. 841-842 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 前間篤,橋本大定,横谷定雄,庄司正弘,幕内雅敏: "表面温度制御法を用いたレーザー治療の基礎的研究-消化管病変に対する可能性-"第6回日本コンピュータ外科学会大会講演論文集. 55-56 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 幕内雅敏,橋本大定,庄司正弘,横谷定雄,渡辺誠: "低侵襲レーザ加熱治療法開発の基礎研究"第6回日本コンピュータ外科学会大会講演論文集. 53-54 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 幕内雅敏,橋本大定,庄司正弘,横谷定雄,渡辺誠,田嶋顕一郎,三宅昌幸: "低侵襲レーザ加熱治療法開発のための基礎研究"第34回日本伝熱シンポジウム講演論文集. 1. 123-124 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Atsushi Maema, Daijo Hashimoto, Sadao Yokoya, Masahiro Shoji and Masatoshi Makuuchi: "New Laser Treatment for Digestive Organs by Laser Irradiation from the serosal side"Proc.20th Annual Meeting of Japan Society for Laser Medicine. 77 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Atsushi Maema, Daijo Hashimoto, Masahiro Shoji, Sadao Yokoya and Masatoshi Makuuchi: "Development of New Laser Treatment Using Surface Cooling Method-An Experimental Study for Digestive Organs"Proc.19th Annual Meeting of Japan Society for Laser Medicine. 79 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Masatoshi Makuuchi, Daijo Hashimoto, Masahiro Shoji, Sadao Yokoya, Atsushi Maema, Makoto Watanabe and Hiroki Fukudome: "Fundamental Study on Development of Laser Coagulation Method (Transmissivity Measurement of Tissue and Experiments of Animals)"Proc.7th Annual Meeting of the Japan Society of Computer Aided Surgery. 125-126 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Atsushi Maema, Daijo Hashimoto, Masatoshi Makuuchi, Masahiro Shoji, Makoto Watanabe and Hiroki Fukudome: "Fundamental Study on Development of Laser Coagulation Method"Proc.35th National Heat Transter Symposium of Japan. Vol.3. 841-842 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Atsushi Maema, Daijo Hashimoto, Sadao Yokoya, Masahiro Shoji and Masatoshi Makuuchi: "Fundamental Study on Surface Temperature Controlled Laser Coagulation Method"Proc.6th Annual Meeting of the Japan Society of Computer Aided Surgery. 55-56 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Masatoshi Makuuchi, Daijo Hashimoto, Masahiro Shoji, Sadao Yokoya and Makoto Watanabe: "Fundamental Study on Low Invasive Laser Coagulation Method"Proc. 6th Annual Meeting of the Japan Society of Computer Aided Surgery. 53-54 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Masatoshi Makuuchi, Daijo Hashimoto, Masahiro Shoji, Sadao Yokoya, Makoto Watanabe, Kenichiro Tajima and Masayuki Miyake: "Fundamental Study on Low Invasive Laser Coagulation Method"Proc.34th National Heat Transfer Symposium of Japan. Vol.1. 123-124 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 前間篤,橋本大定,横谷定雄,庄司正弘,幕内雅敏: "消化管奬膜側からの照射による新しいレーザー治療"第20回日本レーザ医学会大会講演論文集. 77 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 前間、橋本、幕内、庄司、横谷、渡辺、福留: "レーザ加熱治療法開発の基礎研究" 第35回日本伝熱シンポジウム講演論文集. 3. 841-842 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 前間、橋本、庄司、横谷、幕内: "表面温度制御法を用いた新しいレーザ治療法の開発-消化管に対する基礎研究-" 第19回日本レーザ医学会大会 抄録集. 79- (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 幕内、橋本、庄司、横谷、前間、渡辺、福留: "レーザ加熱治療法開発の基礎研究-組織の透過率の測定と動物実験-" 第7回コンピュータ外科学会大会論文集. 125-126 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 前間,橋本,横谷,庄司,幕内: "表面温度制御法を用いたレーザ治療の基礎的研究" 第6回日本コンピュータ外科学会大会講演論文集. 1. 55-56 (1997)

    • Related Report
      1997 Annual Research Report

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Published: 1997-04-01   Modified: 2016-04-21  

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