| Project/Area Number |
09640702
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
機能・物性・材料
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| Research Institution | OKAYAMA UNIVERSITY OF SCIENCE |
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Principal Investigator |
KODAMA Michiko OKAYAMA UNIV.OF SCIENCE,DEPARTMENT OF SCIENCE,PROFESSOR, 理学部, 教授 (40101282)
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| Co-Investigator(Kenkyū-buntansha) |
AOKI Hiroyuki OKAYAMA UNIV.OF SCIENCE,DEPARTMENT OF SCIENCE,ASSOCIATED FROFESSOR, 理学部, 講師 (80248202)
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| Project Period (FY) |
1997 – 1998
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| Project Status |
Completed (Fiscal Year 1998)
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| Budget Amount *help |
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 1998: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1997: ¥3,000,000 (Direct Cost: ¥3,000,000)
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| Keywords | differential scanning calorimetry / Phosphatidylglycerol(PG) / Interlamellar water / Ice-melting DSC curve / Na^<23>-nmα測定 / 示券走査熱量測定 / ファスファチジルグリセロール / 水融解エンタルピー / Na^<23>-nmr測定 / 示差走査熱量測定 / ジミリィストィールフォスファチジルグリセロール / 示差走査熱量測定(DSC) / ネガティブ染色電子顕微鏡観察 / ^<23>Na-NMR(核磁気共鳴) / ベシクル |
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| Research Abstract |
Variation of the thermotropic behavior of both lipid assemblies and associated water molecules with an increase in water content was investigated for negatively charged phosphatidyiglycerol (PG)-water system up to 95 wt.% water by differential scanning calorimetry (DSC). The number of water molecules interposed into interbilayer regions of the present system was estimated from a deconvolution analysis of ice-melting DSC curves On the basis of a result of the calorimetric method, a water distribution diagram was constructed over the water content range from 0 to 95 wt.% water. The diagram revealed a continuous incorporation of freezable interlamellar water up to 95 wt.%, in contrast with a limiting incorporation for neutral lipids such as phosphatidyicholine (PC) and phosphatidylethanolamine (PE). Such a characteristic interlamellar water uptake for PG was discussed from the viwpoint of unilamellar forming property for this lipid.
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