| Project/Area Number |
09640739
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
遺伝
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| Research Institution | Institute of Statistical Mathematics |
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Principal Investigator |
HASEGAWA Masami ISM Professor, 予測制御研究系, 教授 (60011657)
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| Co-Investigator(Kenkyū-buntansha) |
HASHIMOTO Tetsuo ISM Associate professor, 助教授 (50208451)
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| Project Period (FY) |
1997 – 1998
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| Project Status |
Completed (Fiscal Year 1998)
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| Budget Amount *help |
¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 1998: ¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 1997: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Keywords | mitochondrial DNA / protein / molecular phylogeny / ND1 / vertebrate / eutheria / lamprey / shark / NDI / ヤツメウナギ / ND1遺伝子 / 肺魚 / シ-ラカンス / 収斂進化 |
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| Research Abstract |
Several cases of misleading molecular phylogenies estimated from mitochondrial DNA-encoded proteins have been known. In order to clarify the causes of these misleading phylogenies, we conducted several new analyses.
1) ND1 gene gives contradictory tree from that estimated from other genes of mitochondria concerning phylogeny among eutherian orders. In order to distinguish stochastic error due to to small species sampling from convergent substitutions due to some adaptive evolution, we sequenced ND1 gene from several eutherian species as well as several outgroup marsupials.
It turned out that convergent evolution has occurred in ND1 between primates and rodents or between ferungulates and outgroup.
2) By using lamprey as an outgroup in the analysis of mitochondrial proteins, a bizarre tree is obtained in which lamprey groups with lungfish in the vertebrate tree. In order to clarify the reason of this, we sequenced complete mtDNA from shak. With this data as an outgroup, morphologically acceptable tree was obtained, demonstrating that something strange occurred in the lamprey and/or lungflsh lineages.
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