| Project/Area Number |
09650842
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
反応・分離工学
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| Research Institution | Nagaoka University of Technology |
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Principal Investigator |
KOBAYASHI Takaomi Faculty of Engineering, Nagaoka University of Technology Associate Professor, 工学部, 助教授 (90225516)
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| Co-Investigator(Kenkyū-buntansha) |
FUJII Nobuyuki Faculty of Engineering, Nagaoka University of Technology Professor, 工学部, 教授 (50011119)
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| Project Period (FY) |
1997 – 1999
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| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥2,900,000 (Direct Cost: ¥2,900,000)
Fiscal Year 1999: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1998: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1997: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | Molecular imprinting / Functional Membranes / Separation Membranes / Recognition / Temlate / Polymer / Permeability / Membrane separation / 高分子膜 / 鋳型分子 / 分子刷り込み / カフェイン / 相分離法 / ポリアクリロニトリル / ポリアミド / 刷り込み特性 / テオフィリン |
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| Research Abstract |
Phase inversion of polyacrylonitrile copolymers with carboxylic acid groups was applied to prepare molecular imprinting membranes of theophylline (THO). The copolymer cast solution of dimethylsulfoxide (DMSO) with the THO template was immersed in water and then the polymer including the template is coagulated in the nonsolvent. After removal of the template from the solidified copolymer membrane, high selectivity for THO molecule was recognized compared to Caffeine recognition by the THO imprinted-membranes. The molecular imprint process was affected by the template concentration in the DMSO cast solution, coagulation condition and carboxylic acid contents in the copolymer. The high binding selectivity of THO solute to the THO imprinted copolymer membrane arise from the formation of the imprinted sites, which consist of free OH group of carboxylic acid segments for hydrogen bonds with the solute
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