| Project/Area Number |
09670003
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General anatomy (including Histology/Embryology)
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
SATO Kenji TOKYO MEDICAL AND DENTAL UNIVERSITY, FACULTY OF MEDICINE, SCHOOL OF ALLIED SCIENCES, PROFESSOR, 医学部, 教授 (20107246)
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| Co-Investigator(Kenkyū-buntansha) |
KIHARA Kazunori TOKYO MEDICAL AND DENTAL UNIVERSITY, FACULTY OF MEDICINE, UROLOGY, ASSISTANT PROFESSOR, 医学部, 助教授 (40161541)
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| Project Period (FY) |
1997 – 1999
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| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 1999: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1998: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1997: ¥2,200,000 (Direct Cost: ¥2,200,000)
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| Keywords | MORPHOLOGY / NEUROPHYSIOLOGY / ABODOMINO-PELVIC ORGANS / SYMPATHETIC NERVE / CROSS-INNERVATION / NERVE DIFFERENTIATION / SPINAL CENTER / DOG / 自律神経 / 自律神経縫合 / 射精 / 交感神経の中枢 |
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| Research Abstract |
Peripheral sympathetic signals controlling ejaculatory reactions were explored in the dog and man.
1) Our results indicate the presence of two kinds of mechanisms controlling the pelvic organs ; one is the direct nerve-innervating system to the seminal tract with multiple cross-innervation pathways and the other the hormonal system consisting of the greater splanchnic nerve and adrenal medulla.
2) The spinal cord segments nerve-controlling the vas deferens are L1-L4 in the dog and probably L1-L2 in humans and that differentiation of the sympathetic nerve pathways is proceeding at both main and compensatory pathways to the pelvic organs in the primate.
3) There are two sites (caudal mesenteric plexus and prostatic plexus ) where efferent signals from a lumbar splanchnic nerve cross to the other side to control bilateral seminal tracts.
4) In the differentiation of the sympathetic nerve, the caudal mesenteric plexus was divided into two plexuses (inferior mesenteric plexus and superior hypogastric plexus) in the primates. This division is not observed in the dog and observed incompletely in monkeys and completely in humans, which suggests a progressing differentiation of the sympathetic pathway.
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