| Project/Area Number |
09670420
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Aichi Medical University |
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Principal Investigator |
KOBAYASHI Fumio Aichi Medical University, Medicine, Professor, 医学部, 教授 (80135342)
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| Co-Investigator(Kenkyū-buntansha) |
AKAMATSU Yasuhiro Aichi Medical University, Medicine, Assistant Professor, 医学部, 助手 (70257658)
WATANABE Misuzu Aichi Medical University, Medicine, Assistant Professor, 医学部, 助手 (30298624)
FURUI Hikari Aichi Medical University, Medicine, Lecturer, 医学部, 講師 (30238662)
WATANABE Takemasa Osaka Medical University, Medicine, Associate Professor, 医学部, 助教授 (50182928)
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| Project Period (FY) |
1997 – 1998
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| Project Status |
Completed (Fiscal Year 1998)
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| Budget Amount *help |
¥1,800,000 (Direct Cost: ¥1,800,000)
Fiscal Year 1998: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1997: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | Taxi Driver / Autonomic Nervous Activity / Stress / Holter ECG / Complex demodulation method / Blood Pressure / R-R Interval Variability |
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| Research Abstract |
Objectives We investigated work-related effects on sympathetic and parasympathetic nervous activity in taxi drivers.
Methods The subjects were 23 normotensive and 12 hypertensive male taxi drivers. On Holter ECG, changes in the R-R interval were analyzed by a complex demodulation method. Amplitude of the high frequency components (0.30 Hz) was used as the parameter of parasympathetic activity, and the ratio of low-frequency components (0.09 Hz) to high-frequency components (L/H) was used as the parameter of sympathetic activity. Autonomic nervous activity was compared before and after cigarette smoking. Ambulatory blood pressure was recorded automatically at 30-min intervals. As reference groups, un-treated healthy day shift male workers, with (n=6) and without (n=7) hypertension were examined.
Results Blood pressure on the working day was significantly higher as a whole, in blood pressure. Sympathetic activity on the working days was insignificantly higher than that on holidays. In hypertensive drivers, parasympathetic activity on working days was significantly lower than that on the first day of a holiday. In hypertensive drivers, high sympathetic activity persisted until the night on working days, and parasympathetic activity was suppressed during the day time. Sympathetic activity was significantly increased within 5 minutes after smoking between 20 : 00-22 : 00 hours, and parasympathetic activity was suppressed after smoking between 14 : 00-19 : 00 hours.
Conclusions Taxi-driving work maintained blood pressure throughout the day, increased sympathetic activity, and suppressed parasympathetic activity. This tendency was more apparent in hypertensive drivers. Smoking accelerated sympathetic and suppressed parasympathetic activity especially at night.
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