| Project/Area Number |
09671189
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
KIMURA Yoshitaka (1999) Tohoku University Hospital, Research Associate, 医学部・附属病院, 助手 (40261622)
渡辺 孝紀 (1997-1998) 東北大学, 医学部附属病院, 講師 (70221687)
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| Co-Investigator(Kenkyū-buntansha) |
OKAMURA Kunihiro Graduate School of Medicine, Tohoku University, Professor, 大学院・医学系研究科, 教授 (90124560)
木村 芳孝 東北大学, 医学部附属病院, 助手 (40261622)
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| Project Period (FY) |
1997 – 1999
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| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 1999: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1998: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1997: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Keywords | Power spectrum / Fetal distress / High frequency area / HF領域 / 羊実験モデル / 胎児心拍数 / パワースペクトル成分 / 低酸素血症 / ドプラ / スペクトル解析 / 胎児生理学 |
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| Research Abstract |
The purposes of this study were to clarify the change of the fetal heart rate variability by using power spectral analysis in fetal distress. In 1998 we studied experimentally the change of fetal heart rate spectral structure of lamb under repeated umbilical cord occlusions. It was known that the power spectrum is constructed with two main frequency areas, one is low frequency area (about 0.1 Hz), which changes correlating with the sympathetic nervous system in fetal lamb, another is high frequency area (about 0.3-0.5 Hz), which is partially correlating with parasympathetic nervous system. In this year we found that the mode of the low frequency area during 1 hour is decreasing in fetal hypoxemia. And the high frequency area, which changes corresponding with the low frequency area in normal condition, changed differently than the low frequency area in hypoxemia. Especially the transient increase of frequency area was frequently noticed only in high frequency area in severe hypoxemia.
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