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Anal function after ileocolonic interposition pouch in low anterior resection for rectal cancer patients

Research Project

Project/Area Number 09671323
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Digestive surgery
Research InstitutionNagasaki University

Principal Investigator

NAKAGOE Tohru  First Department of Surgery, School of Medicine, Nagasaki University, Associate professor, 医学部, 助教授 (40188917)

Co-Investigator(Kenkyū-buntansha) KUROSAKI Nobuko  First Department of Surgery, Nagasaki University Hospital, Associate professor, 医学部・附属病院, 講師 (50253646)
Project Period (FY) 1997 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2000: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1999: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1998: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1997: ¥2,400,000 (Direct Cost: ¥2,400,000)
Keywordsrectal cancer / ileocolonic interposition pouch / low anterior resction / 回盲部間置術
Research Abstract

BACKGROUND/AIM : Ileocolonic interposition pouch (IIP) is a new candidate for pouch operation for rectal cancer patients, in which an ileocolonic segment is interposed between anal canal and descending colon after rectal cancer resection with total mesorectal excision. The aim of this study was to compare postoperative anal function utilizing IIP with those of the conventional straight type reconstruction (end-to-end sigmoid-anal canal anastomosis).
PATIENTS AND METHODS : Seventeen rectal cancer patients who underwent IIP between 1995 and 200 were prospectively studied (IIP group). Twenty-six rectal caner patients who underwent conventional straight type reconstruction during same period served as the control group (Straight group). The operative outcomes, bowel movement, colonic transit time (using by SITZMARKS【○!R】), and manometric study between two groups were compared.
RESULTS : The clinicopathological features of tumors and operative morbidity between two groups did not differ. Mean times of bowel movement at 1/3/6/12/24/36/48 month (s) after surgery is as follows : 9.4/6.3/5.6/4.7/3.9/ 3.2/3.7 (per day) in patients with IIP group and 11.6/7.6/6.4/5.1/4.1/3.9/4.5 (per day) in patients with Straight group, respectively. The mean (±standard deviation) of colonic transit time (half-dose) is as follows : 31.2 (±17.6) hours in patients with IIP group ; 65.1 (±38.8) hours in patients with Straight group ; 28.8 (±9.5) hours in healthy subjects. The manometric studies between two groups did not differ.
CONCLUSION : The reconstruction using IIP may decrease the times of bowel movement and normalized the colonic transit time after surgery, forming an attractive alternative pouch operation in rectal cancer patients. The IIP may serve attractive features as follows : 1) preservation of nerve supply to pouch ; 2) no mobilization around the splenic flexure ; 3) intact pouch wall ; 4) no diversion.

Report

(5 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • 1997 Annual Research Report
  • Research Products

    (10 results)

All Other

All Publications (10 results)

  • [Publications] 中越享: "直腸癌低位前方切除術におけるIleocolonic Interpostion Pouch"手術. 50. 1913-1916 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 中越享: "直腸癌低位前方切除術後の回結腸間置によるパウチ手術"手術. 54. 1063-1068 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Tohru Nakagoe, Terumitsu Sawai, Osamu Sasano, Hiroyuki Yamaguchi, Atsushi Nanashima, Toru Yasutake, Hiroyuki Kusano, Hiroyoshi Ayabe: "Ileocolonic interposition pouch in low anterior resection for rectal cancer patients"Operation. 50. 1903-1916 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Tohru Nakagoe, Terumitsu Sawai, Takashi Tsuji, Nobuko Kurosaki, Hiroyoshi Ayabe: "A new pouch operation using ileocolonic interposition after low anterior resection for rectal cancer patients"Operation. 54. 1063-1068 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 中越享: "直腸癌低位前方切除術におけるIleocolonic Interposition Pouch"手術. 50・11. 1913-1916 (1996)

    • Related Report
      2000 Annual Research Report
  • [Publications] 中越享: "直腸癌低位前方切除後の回結腸間置によるパウチ手術"手術. 54・8. 1063-1068 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 中越亨: "直腸癌低位前方切除術におけるIleocolonic Interposition Pouch"手術. 50・11. 1913-1916 (1996)

    • Related Report
      1999 Annual Research Report
  • [Publications] 中越亨: "Pouch Operationの手技とピットフォール:直腸癌低位前方切除後"手術. (未定). (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 中越 亨: "直腸癌低位前方切除術におけるIleocolonic Interposition Pouch" 手術. 50・11. 1913-1916 (1996)

    • Related Report
      1998 Annual Research Report
  • [Publications] 中越 享: "直腸癌低位前方切除術におけるIleocolonic Interposition Pouch" 手術. 50・11. 1913-1916 (1996)

    • Related Report
      1997 Annual Research Report

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Published: 1997-04-01   Modified: 2016-04-21  

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