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Characterization of intraductal papillary tumor of the pancreas

Research Project

Project/Area Number 09671350
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Digestive surgery
Research InstitutionFukuoka Univ.ersity

Principal Investigator

IKEDA Seiyo  Fukuoka Univ., School of Medicine, Professor, 医学部, 教授 (40038758)

Project Period (FY) 1997 – 1998
Project Status Completed (Fiscal Year 1998)
Budget Amount *help
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 1998: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1997: ¥2,100,000 (Direct Cost: ¥2,100,000)
Keywordspancreas tumor / intraductal papillary tumor / AgNOR / Ki-67 / p53 / ERP / 遺伝子解析 / p-53
Research Abstract

Recently, there has been an increase in number of cases with intraductal papillary tumor of the pancreas. It includes hyperplasia, adenoma, non-invasive and invasive carcinoma based on the pathological diagnosis. However, the precise feature of intraductal papillary tumor of the pancreasremain sunknown. In the present study, clinical and pathological characteristics of intraductal papillary tumor of the pancreas were analyzed.
The Clinical analysis of our cases with intraductal papillary tumor of the pancreas apppeared in Hepato-Gastroenterology 45 : 1986-1995,1998
The results of clinicopathological and molecular biological studies on intraductal papillary tumors of the pancreas are as follows. The mean AgNOR counts and Ki-67LI as well as overexpression of p53 protein increased with the grade of malignancy from carcinoma to hyperplasia. Similarly, the mean TUNEL index (TI) was increased with malignancy The findings suggest that molecular and biological procedures will facilitate to afford further precise diagnosis of intraductal papillary tumor of the pancreas.

Report

(3 results)
  • 1998 Annual Research Report   Final Research Report Summary
  • 1997 Annual Research Report
  • Research Products

    (5 results)

All Other

All Publications (5 results)

  • [Publications] 中山吉福, 池田靖洋 et al.: "膵管内乳頭腫瘍の良悪性について、特に分子生物学的側面から" 病理と臨床. 15(7). 604-610 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Kensei Maeshiro, Seiyo Ikeda et al.: "Diagnosis of muchin-producing tumor of the pancreas by balloon-catherter endoscopic retrograde pancreatography-compression study" Hepato-Gastroenterology. 45. 1986-1995 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Kensei Maeshiro, Yoshifuku Nakayama, Yohichi Yasunami, Koh Furuta, Seiyo Ikeda: "Diagnosis of mucin-producing tumor of the pancreas by balloon-catherter endoscopic retrograde pancreatography-compression study." Hepato-Gastroenterology. 45. 1986-1995 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] K. Maeshiro, Y. Nakayama Y. Yasunashi, K. Fujita, S. Ikeda: "Diagrams of Mucin-production Tumor of the panereas by balloon-catheter endoscopic retrograde pancroatography-compression Study" Hepato-Gastroeutesobigy. 45・24. 1986-1995 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 中山吉福,岩永真一,岩崎宏,村山寛,大島彦一,菊池昌弘,真学城兼清,宮崎宏,池田靖洋: "膵管内乳頭腫瘍の良悪性について-特に分子生物学的側面から-" 病理と臨床. 15・7. 604-610 (1997)

    • Related Report
      1997 Annual Research Report

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Published: 1997-04-01   Modified: 2016-04-21  

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