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Experimental Study of Transplantation of Autograft from the Lobar Bronchus to Close the Tracheal Defect

Research Project

Project/Area Number 09671393
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionShowa University

Principal Investigator

SUZUKI Takashi  Showa University, School of Medicine, Associate Professor, 医学部, 助教授 (60118958)

Co-Investigator(Kenkyū-buntansha) SUZUKI Shuichi  Showa University, School of Medicine, Assistant, 医学部, 助手 (80245860)
KITAMI Akihiko  Showa University, School of Medicine, Assistant, 医学部, 助手 (20241036)
Project Period (FY) 1996 – 1998
Project Status Completed (Fiscal Year 1998)
Budget Amount *help
¥1,900,000 (Direct Cost: ¥1,900,000)
Fiscal Year 1998: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1997: ¥1,400,000 (Direct Cost: ¥1,400,000)
KeywordsTracheobronchoplasty / Lung cancer / Tracheal carcinoma / Omentopexy / Transplantation of bronchus / Bronchial epithelium / Scanning electron microscopy / Tracheal prosthesis / 気管形成術 / 気管切除
Research Abstract

We studied the efficacy of autograft of a lobar bronchus to a large defect of the trachea (one-third of circumferential wall, six rings length) experimentally in dogs. The efficacy of wrapping of omentum or mediastinal tissue was also stucfied The autograft was obtained from the wail of the right upper lobe bronchus. Trimming of the lobar bronchus and the segmental bronchi made a relatively flat plane of bronchial wall. This autograft was transplanted to the defect to the right wall of the lower trachea. The results showed that this type of aubograft was effective if wrapping was added, and omentopexy was more reliable than the wrapping by mediastinal tissue. This study showed that the repair for the large defect of the tracheal wall could be performed successfully by the autograft obtained from the bronchi and omentopexy.

Report

(3 results)
  • 1998 Annual Research Report   Final Research Report Summary
  • 1997 Annual Research Report
  • Research Products

    (3 results)

All Other

All Publications (3 results)

  • [Publications] 鈴木 隆: "切除した気管の欠損部に対し自己肺葉からえた遊離気管支片で補填を行った実験的検討" 日本胸部外科学会雑誌. 46号増刊. 422 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] Suzuki T.et al.: "Experiment of repairing the large defect of the lower trachea by autograft obtained from the bronchus." The Japanese Journal of THORACIC AND CARDIOVASCULAR SURGERY. 46 sppl.(1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 鈴木 隆: "切除した気管の欠損部に対し自己肺葉からえた遊離気管支片で補填を行った実験的検討" 日本胸部外科学会雑誌. 46号増刊. 422 (1998)

    • Related Report
      1998 Annual Research Report

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Published: 1997-04-01   Modified: 2016-04-21  

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