| Project/Area Number |
09671394
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Tokyo Medical University |
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Principal Investigator |
SAITO Makoto Medicine, Tokyo Medical University, Assistant Professor, 医学部, 講師 (30225734)
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| Co-Investigator(Kenkyū-buntansha) |
URYU Kazuto Medicine, Tokyo Medical University, Assistant, 医学部, 助手 (40287123)
KONAKA Chimori Medicine, Tokyo Medical University, Associate Professor, 医学部, 助教授 (70147180)
KATO Harubumi Medicine, Tokyo Medical University, Professor, 医学部, 教授 (20074768)
ONODA Toshiya Medicine, Tokyo Medical University, Assistant, 医学部, 助手 (70307312)
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| Project Period (FY) |
1997 – 1999
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| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1999: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1998: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1997: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Pulmonary function / Chest CT / Intrathorasis organs / CT value / Helical CT |
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| Research Abstract |
We developed pulmonary function test using chest computed tomogram (CT). Previous study using conventional CT showed that CT value form -1024 to -200 HU as A200 indicated total lung volume and CT value from -1024 to -920 HU as A910 indicated total volume of bullous change. EVV (A200-A910) and IVR (A910/A200) also showed an additional information of CT pulmonary test. We also showed these factors by conventional CT could apply to factors by helical CT. Comparison of pulmonary function between spirometry as conventional pulmonary function test and CT pulmonary function test was evaluated in 32 lung cancer cases. Correlation between A910 and FEV1.0, A200 and VC was found (P=0.032). Correlation between A910 and %FEV1.0 (p=0.0118), IVR and V50 (p=0.0227) was also found. Helical CT pulmonary function test provided shorter examination time than conventional CT test (110 minutes vs. 12 minutes) and showed target area as 3D graphics. Comparison of ventilation-perfusion scintigram using SPECT and CT pulmonary function test was evaluated. A little correlation between A200 and SPECT (p=0.053), IVR and SPECT (p=0.05) was found. CT pulmonary function test had additional information of pulmonary function.
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