| Project/Area Number |
09671484
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Nagoya University |
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Principal Investigator |
TORII Shuhei Nagoya University, School of Medicine, Professor, 医学部, 教授 (60115607)
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| Co-Investigator(Kenkyū-buntansha) |
KAMEI Yuzuru School of Medicine, Associate Professor, 医学部, 助教授 (10257678)
西関 修 名古屋大学, 医学部, 医員
長谷川 隆 名古屋大学, 医学部, 講師 (50281069)
江崎 茂 名古屋大学, 医学部, 医員
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| Project Period (FY) |
1997 – 1999
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| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 1999: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1998: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1997: ¥800,000 (Direct Cost: ¥800,000)
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| Keywords | lower extremities / skin flap / musclocutaneous flap / omental flap / reconstruction / endoscopic harvest / 内視鏡手術 / マイクロサージャリー / 大網 / 骨髄炎 / 難治性潰瘍 / 血管新生 / 二分脊椎 |
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| Research Abstract |
We studied long term follow up study and development of skin and musclocutaneous flap in lower extremities and effects of wound healing using omental flap or muscle flap at 1997 to 1999.
We investigated 122 patients that were followed up over 3 years after reconstruction of bone or soft tissue malignant tumors in extremities. Using skin/musclocutaneous skin flap with bone/artificial joint could avoid a amptation and contributed to the patient's satisfaction, the improvement of quality of life. In some cases with large bone defects, we transfered the heat-treated bone for reduction of operating invasion. In this cases, covering in the muscle flap with rich blood circulation especially was useful. And we brought up a series of protocol for chronic intractable ulcer etc. with spina bifida or diabetes. The protocol was based by long term follow up, not only surgical treatment, but also conservative treatmental and rehabilitation. Now we developed and successed new flap methods for example that vascularized fibula and omental flaps convined intractable non-union.
As for the omental flap, we investigated the effect of lipid fraction in rat omentum, and indicated the omentum lipid fraction made extension of survival area in flaps, vasodilation and vascularization in flaps and surrounding tissue. We aggressively used the omental flap had characteristic plasticity and possibility for bridging of vessel and extended the indication. By the combination of omental flap and other flaps, we obtain satisfactory results for the difficult cases in lower extremes. And, we devised new methods of harvest of omental flap. For decreasing of operation invasion and harvest time, we tried endoscopic harvest, mini-laparotomy with endoscope and endoscopic harvest with hand-port. These were announced in some meeting.
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