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超伝導量子干渉装置を用いた味覚受容の研究

Research Project

Project/Area Number 09671751
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionKYUSHU UNIVERSITY

Principal Investigator

YAMAMOTO Tomoya  KYUSHU UNIVERSITY ASSOCIATE PROFESSOR, 医学部, 講師 (30230577)

Co-Investigator(Kenkyū-buntansha) 山下 弘之  九州大学, 医学部, 助手 (10264029)
Project Period (FY) 1997 – 2000
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 1999: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1998: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1997: ¥2,900,000 (Direct Cost: ¥2,900,000)
KeywordsMEG / SQUID / taste / somatosensory / Operculm / human brain / magnetic evoked potential / Otolaryngology / magnetoencephalography / 口腔知覚 / 嚥下障害 / QOL
Research Abstract

Evoked magnetic response revealed that the somatosensory receptive field of oral, pharyngeal and laryngeal stimulation was located at the Operculm in the human brain. Taste receptive field was also localized in the Operclum close to the Insula region.
Resent progress in the magnetoencephalography (MEG) utilizing the super-conductive interference device (SQUID) made it possible to record the extremely weak magnetic signal emitted from the human brain. In the current paper, author developed the computer controlled device which stimulate the oral, pharyngeal and laryngeal mucosa by air-puff. This device also provided the taste solution to stimulate gustatory receptors in the tongue.

Report

(4 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • 1997 Annual Research Report
  • Research Products

    (20 results)

All Other

All Publications (20 results)

  • [Publications] Morioka T, Nishio S, Ishibashi H, Muraishi H, Muraishi M, Hisada K, Shigeto H, Yamamoto T, Fukui: "M: Intrisic epileptogenicity of focal cortical dysplasia as revealed by magneto-encephalography and electrocorticography."Epilepsy Reserch. 33. 177-187 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Yamashita H, Kymamoto Y, Nakashima Y, Yamamoto Y, Inokuchi A, Komiyama: "S: Magnetic sensory cortical responses evoked by tactile stimulations of the human face, oral cavity and flap reconstrctions of the tongue"Eur Arch Otorhino-laryngol. 256. 42-46 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Miyazaki H, Yamashita H, Masuda T, Yamamoto T, Komiyama: "S: Transcutaneous PPPCO2 monitoring in the evaluation of hyperventilation of patients with recurrent nerve paralysis"Eur Arch Otorhinolaryngol. 256. 47-50 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Ikeda Y, Masuda T, Manako H, Yamashita H, Yamamoto T, Komiyama: "S : Quantitative evaluation of the voice range profile in patients with voice disorder."Eur Arch Otohinolaryngol. 256. 51-55 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Kuratomi Y, Kumamoto Y, Yamashita H, Yamamoto T, Inokuchi A, Tomita K, Masuda A, Uehara S, Ohmagari J, Jingu K, Komiyama: "S: Comparison of survival rates of patients with nasopharyngeal carcinoma treated with radiotherapy, 5-fluorouracil and vitamin A("FAR" therapy)vs FAR therapy puls adjunctive cisplatin and pepleomycin chemotherapy"256. 60-63 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Onitsuka T, Ninomiya H, Sato E, Yamamoto T, Tashiro: "N: The effect of interstimulus intervals and between-block rests on the auditory evoked potential and magnetic field : is the auditory p50 in humans an overlapping potential?"Clinical Neurophysiol. 110. 1-9 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Morioka T: "Magnetic source imaging of the sensory cortex on the surface anatomy MR scanning" Neurol Res. 20. 235-241 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Ishibashi H: "Three-dimensional localization of subclinical ictal activity by magnetoencephalography:correlation with invasive monitoring" Surg Neurol. 50. 157-163 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Shigeto H: "Visual evoked cortical magnetic responses to checkerboard pattern reversal situmulation:a study on the nerral generators of N75,P100 and N145" J Neurol Sci. 156. 186-194 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Ishibashi H: "Magnetoencephalographic evaluation of anterior corpus callosotomy for intractable epilepsy in a patient with Lennox-Gaustaut syndrone" J Epilepus. 11. 202-207 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 山本智矢: "臨床診断における脳磁図の有用性と限界" 臨床脳波. 40. 635-639 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 森岡隆人: "脳梁脂肪腫:神経磁気計測装置(magentoencephalography:MEG)による病態解析" 臨床脳波. 40(6). 414-418 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 山本智矢: "耳鼻咽喉科・頭頚部外科クリニカルトレンドPart 2 脳磁図で何がわかるか" 中山書店, 5 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 山本智矢: "小児の脳磁図" 小児耳鼻咽喉科. 118・2. 21-25 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Gondo,K: "Case of Epilepsy with speech disordes EEG changes and magnetoencepha lographic analysis." J.Epilepsy. 10. 73-77 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] Shinji,Y: "Magnetoencephalographic analysis of Hypsarrhythmia in West syndrome" J.Epilepsy. 10. 131-138 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 山下弘之: "輪状咽頭筋切断術の適応と限界" 耳鼻と臨床. 43. 690-695 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 山下弘之: "口腔・咽頭知覚と嚥下機能:SQUIDの臨床への応用" 口腔咽頭科学. 9・3. 349-354 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 山本智矢: "脳磁図の耳鼻咽喉科への応用" 日本耳鼻咽喉科専門医通信. 53. 30-31 (1998)

    • Related Report
      1997 Annual Research Report
  • [Publications] 山本智矢: "中山書店" 脳磁図で何がわかるか(耳鼻咽喉科・頭頸部外科クリニカルトレンド Part2), 1 (1998)

    • Related Report
      1997 Annual Research Report

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Published: 1997-04-01   Modified: 2016-04-21  

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