| Project/Area Number |
09671752
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Saga Medical School |
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Principal Investigator |
SHIN Takemoto Saga Medical School, Faculty of Medicine, Professor, 医学部, 教授 (70080869)
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| Co-Investigator(Kenkyū-buntansha) |
TSUNETOMI Kyoko Saga Medical School, Faculty of Medicine, Research Associate, 医学部, 助手 (80304898)
SUGIMOTO Toshihiko Saga Medical School, Faculty of Medicine, Research Associate, 医学部, 助手 (70304912)
TAKAGI Seiji Saga Medical School, Faculty of Medicine, Research Associate, 医学部, 助手 (60284634)
OOTANI Shinji Saga Medical School, Faculty of Medicine, Research Associate, 医学部, 助手 (80274596)
TSUDA Kuniyoshi Saga Medical School, Faculty of Medicine, Assistant Professor, 医学部, 講師 (40207387)
宮崎 純二 佐賀医科大学, 医学部, 助手 (50284633)
安達 朝幸 佐賀医科大学, 医学部, 助手 (40260731)
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| Project Period (FY) |
1997 – 1998
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| Project Status |
Completed (Fiscal Year 1998)
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| Budget Amount *help |
¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 1998: ¥200,000 (Direct Cost: ¥200,000)
Fiscal Year 1997: ¥3,100,000 (Direct Cost: ¥3,100,000)
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| Keywords | nucleus of the tractus solitarius (NTS) / parvocellular reticular formation / swallowing-related neurons (SRNs) / orthodromic inputs / 上喉頭神経 / 脳幹正中矢状切断 / 一側嚥下 / 対称性嚥下 |
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| Research Abstract |
Swallowing-Related neurons (SRNs) were recorded systematically in the medulla oblongata of urethane anesthetized cats. The SRNs received orthodromic inputs from the superior laryngeal nerve (SLN) and showed transient changes in their activity synchronous with swallowing. These neurons could be divided into three types. Type I SRNs are sensory-relay neurons from the SLN in the nucleus of the tractus solitarius (NTS), type II are interneurons located diffusely in the parvocellular reticular formation ventral to the NTS, which received oligosynaptic inputs from the SLN, and type UI are motoneurons in the nucleus ambiguus. Some type II neurons still showed the swallowing activity after the animals were paralysed, which suggests that they could be involved in the generation of swallowing outputs.
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