| Project/Area Number |
09671859
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Morphological basic dentistry
|
|---|
| Research Institution | KYUSHU UNIVERSITY (1998)
Kagoshima University (1997) |
|---|
Principal Investigator |
TABATA Shoji Faculty of Agriculture, Department of Animal Science, KYUSHU UNIVERSITY Associate Professor, 農学部, 助教授 (40145503)
|
|---|
| Project Period (FY) |
1997 – 1998
|
| Project Status |
Completed (Fiscal Year 1998)
|
| Budget Amount *help |
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 1998: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1997: ¥2,700,000 (Direct Cost: ¥2,700,000)
|
|---|
| Keywords | dental pulp / blood vessel / nerve fiber / immunocytochemistry / SEM / neurotransmitter / 神経 / 電子顕微鏡 / 免疫組織化学 |
|---|
| Research Abstract |
The innervation pattern of blood vessels in the dental pulp was investigated by scanning electron microscopy after connective tissue digestion and by transmission electron microscopy after immunohistochemical localization with polyclonal anti-PGP and anti-suhstance P antibodies. SEM specimens revealed that unmyelinated nerve fibers passed through the tunica adventitia of the blood vessels in the center of the pulp and that these fibers then entered the tunica media of the smaller arterioles. The nerve fibers divided into many collateraIs, and these terminated on the surface of smooth muscle cells and endothelial cells. The terminal fibers then reached the subodontoblastic capillary plexus and terminated on pericytes. The same results were confirmed by immunoelectron microscopy both with polyclonal anti-PGP and anti-substance P antibodies. The present study demonstrated that in the dental pulp the microvasculature as well as larger vessels were directly innervated by free nerve endings, suggesting that the local regulation of blood vessels of blood flow could take place not only at larger vessels but also at the level of the microvasculature in this tissue.
|
