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Lymph node metastasis of oral cancer with 18FDG-PET

Research Project

Project/Area Number 09671929
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 病態科学系歯学(含放射線系歯学)
Research InstitutionIwate Medical University

Principal Investigator

SHOZUSHIMA Masanori  School of Dentistry, Iwate Medical University, Associate Proffesor, 歯学部, 助教授 (00118259)

Co-Investigator(Kenkyū-buntansha) SHIRAKURA Yoshiyuki  School of Dentistry, Iwate Medical University, Research Assistant, 歯学部, 助手 (90254797)
小田 純子  岩手医科大学, 歯学部, 助手 (20275580)
Project Period (FY) 1997 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 1999: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1998: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1997: ¥2,000,000 (Direct Cost: ¥2,000,000)
KeywordsFDG / PET / head and neck cancer / lymphnode metastasis / Image diagnosis / リンパ節転移 / 頭頸部 / 悪性腫瘍 / 口腔癌
Research Abstract

The image fusion of PET and CT from the head and neck region was performed with the use of external markers in 7 patients with squamous cell carcinoma. The purpose of this study was to examine a resultant error and clinical usefulness of the image fusion.
Patients had primary lesion of the tongue, the maxillary gingiva or the maxillary sinus. All patients underwent PET with FDG and CT to detect tumor sites. Of these 7 patients, 6 cases were also pronounced regional lymph node metastasis to the neck from the diagnostic images and the clinical observation. To ensure anatomical detail of the PET images, small radioactive markers were placed on the philtrum and below both earlobes. The PET image and CT image were then overlapped each other on a computer.
The image fusion of PET and CT was achieved in all patients. The superposition error of this method was examined between PET and CT images. The accuracy of fit measured as the mean distance between PET and CT image was in the range of 2 - 5 mm. PET-CT superimposed images produced localization of tumor FDG uptake increase and FDG uptake to palatine tonsil were also localized.
The marker system described here for the alignment of PET and CT images can be used on a routine bases without the invasive fixation of external markers, improve the management and follow up of patients with head and neck carcinoma.

Report

(4 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • 1997 Annual Research Report
  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] 小豆島正典: "頭頸部癌症例におけるPETとCTとの画像合成について"NMCC共同利用研究成果報文集. 6. 45-49 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 小豆島正典: "頭頸部領域におけるCT像とFDG-PET像との重ね合わせ画像の臨床的検討"岩医大歯誌. 24. 28-35 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 小豆島正典: "頭頸部領域におけるリンパ節転移様のFDG集積"NMCC共同利用研究成果報文集. 5. 27-33 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 小田純子: "18FDG-PETによる転移性リンパ節の診断"NMCC共同利用研究成果報文集. 4. 41-51 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Shozushima,M: "Study on Image fusion between FDG-PET and CT In the head and neck cancer"NMCC Annual Report. vol.6,. 45-49 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Shozushima,M.: "Clinical study of the Image fusion between CT and FDG-PET In the head and neck region"Dent.J.Iwate Med. Univ.. vol.24. 28-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Shozushima,M.: "FDG-uptake similar to lymph node metastasis In head and neck"NMCC Annual Report. vol.5. 27-33 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Oda,J: "Detection of lymph node metastasis of carcinomas of the oral cavity with 18FDG-PET"NMCC Annual Report. vol.4. 41-51 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 小豆島 正典: "頭頸部癌症例におけるPETとCTとの画像合成について"NMCC共同利用研究成果報文集. 6. 45-49 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 小豆島 正典: "頭頸部領域におけるCT像とFDG-PET像との重ね合わせ画像の臨床的検討"岩医大歯誌. 24. 28-35 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 小豆島 正典: "頭頸部領域におけるリンパ節転移様のFDG集積"NMCC共同利用研究成果報文集. 5. 27-33 (1998)

    • Related Report
      1999 Annual Research Report
  • [Publications] 小田 純子: "18FDG-PETによる転移性リンパ節の診断"NMCC共同利用研究成果報文集. 4. 41-51 (1997)

    • Related Report
      1999 Annual Research Report
  • [Publications] 小豆島正典: "頭頸部領域におけるリンパ節転移様のFDG集積" NMCC共同利用研究成果報文集. 5. 27-33 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 小豆島正典: "^<18>FDG-PEによる転移性リンパ節の診断" NMCC共同利用研究成果報文集. 4. 40-51 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] 小田純子: "^<18>FDG-PETによる転移性リンパ節の診断" NMCC共同利用研究成果報文集. 4. 40-51 (1997)

    • Related Report
      1997 Annual Research Report

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Published: 1997-04-01   Modified: 2016-04-21  

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