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A biochemical or immunochemical new method for measuring the UV protection efficiency on sunscreen goods

Research Project

Project/Area Number 09680011
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 家政学
Research InstitutionOchanomizu University

Principal Investigator

YAMANO Haruko  Ochanomizu Univ., School of Human Life and Environmental Science, Research Associate, 生活科学部, 助手 (90242338)

Co-Investigator(Kenkyū-buntansha) OGAWA Shojiro  Ochanomizu Univ., School of Human Life and Environmental Science, Professor, 生活科学部, 教授 (20013196)
Project Period (FY) 1997 – 1998
Project Status Completed (Fiscal Year 1998)
Budget Amount *help
¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1998: ¥700,000 (Direct Cost: ¥700,000)
KeywordsUltraviolet rays, (UV) / Ozone layer / Flon / Skin cancer / p53 protein / Apoptosis / UV protein goods / SPF value / 地球環境 / 癌抑制遺伝子
Research Abstract

In recent years, ozone layer is decreasing artifically for flon, life on the earth is exposed hazardous UV irradiation. Therefore sunscreen goods with UV protection have developted one after another. The determination of the cutting ratio of UV protection has measured by photometry or sun protection factor(SPF)value. But the measurement by optical instrument not reflects biological responses. And measurement of SPF value is dangerous because this is carried out on human skin. Accordingly, we have projected the new methods for measuring the UV protection by biochemical or immunochemical determination. After UV irradiation we assayed the decrease of the enzyme activity of the enzyme solution placed in the culture dishes covered with UV protection cloth. This corresponded to the results of photometry or measurement of SPF value. Recently, it was proved that tumor-suppressor protein p53 acts as the key protein in the regulation of cell cycle or apoptosis, a mechanism for eliminating unwanted cells from the cell community in multicellular organisms. The other, recent studies indicate that levels of p53 increase rapidly in response to DNA damage induced by UV irradiation. Accordingly we planned to measure the levels of p53 protein in cultured cells after UV irradiation. Various established cell lines in dishes covered with UV cutting cloth or reference cloth were irradiated by UV, these cell proteins were recovered. Then the levels of p53 protein were measured and calculated the cutting ratio of IIV protection cloth. At present we are examinating the culture condition of cells and UV irradiational condition. In recent years it is proved not only UVB but also UVA is harmful to the skines, specially UVA induce suntan and aging of skin. Therefor we are investigating the calculation of the cutting ratio of sunscreen goods with UVA protection.

Report

(3 results)
  • 1998 Annual Research Report   Final Research Report Summary
  • 1997 Annual Research Report
  • Research Products

    (24 results)

All Other

All Publications (24 results)

  • [Publications] 佐藤真理子: "季節変動からみた発汗の動的特性" 繊維学会誌. 54. 309-314 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 佐藤真理子: "高性能局所発汗量測定装置の開発" 繊維学会誌. 54. 290-292 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 佐藤真理子: "生体リズムの異なる位相における発汗挙動の周波数解析" 日本生理人類学会誌. 2. 117-124 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 雨宮 敏子: "セラミックス加工布の遠赤外線効果に関する研究" 神奈川県産業技術総合研究所 産学公交流研究発表会資料. 306-307 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] T.Nakajima: "A New Apparatus for the Measurement of Local Sweat Rate" お茶の水女子大学人間文化研究年報. 19. 244-253 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 中島 利誠: "衣服内温湿度の変動に関する研究" 日本繊維製品消費科学会年次大会研究発表要旨. 92-93 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] M.Sato, H.Yamano, T.Nakanishi and T.Nakajima: "Seasonal Variation of dynamic Properties in Sweating Activity" Journal of The Society of Fiber Science and Technology Japan. 54. 309-314 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] M.Sato, H.Hasegawa, H.Yamano, T.Nakanishi and T.Nakajima: "An Improved Apparatus for Measuring the Local Sweat Rate" Journal of The Society of Fiber Science and Technology Japan. 54. 290-294 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] M.Sato, H.Yamano, T.Nakanishi and T.Nakajima: "Power Spectral Analysis in Sweating Activity at the Different Phases of Biological Rhythm Applied Human Science" Journal of Physiological Anthropology. 2. 117-124 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] T.Amemia, H.Yamano, T.Nakanishi, M.Onoue and T.Nakajima: "The Study of the Ceramic Treatment Cloth with Effect Of farinfrared ray" Bulletin of the kanagawa Industrial Technology Research Institute. 306-307 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] T.Nakajima, N.Susuki, N.Tsuchiya, J.Hoshi , H.Yamano and Y.Kamata: "A New Apparatus for the Measurement of Local Sweat Rate" Bulletin of the Doctral Research Course in Human Culture. 19. 244-253 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] T.Nakajima, H.Yamano and H.Hasegawa: "The Variation of the Temperature and humidity in the Clothing" Annual report of The Japan Research Association for Textile End-Uses. 92-93 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1998 Final Research Report Summary
  • [Publications] 佐藤真理子: "季節変動からみた発汗の動的特性" 繊維学会誌. 54巻. 309-314 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 佐藤真理子: "高性能局所発汗量測定装置の開発" 繊維学会誌. 54巻. 290-292 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 佐藤真理子: "生体リズムの異なる位相における発汗挙動の周波数解析" 日本生理人類学会誌. 2巻. 117-124 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] 雨宮 敏子: "セラミックス加工布の遠赤外線効果に関する研究" 神奈川県産業技術総合研究所産学公交流研究発表会資料. 306-307 (1996)

    • Related Report
      1998 Annual Research Report
  • [Publications] T.Nakajima: "A New Apparatus for the Measurement of Local Sweat Rate" お茶の水女子大学人間文化研究年報. 19巻. 244-253 (1995)

    • Related Report
      1998 Annual Research Report
  • [Publications] 中島 利誠: "衣服内温湿度の変動に関する研究" 日本繊維製品消費科学会年次大会研究発表要旨. 92-93 (1995)

    • Related Report
      1998 Annual Research Report
  • [Publications] 佐藤 真理子: "生体リズムの異なる位相における発汗挙動の周波数解析" 日本生理人類学会誌. 2巻・3号. 9-16 (1997)

    • Related Report
      1997 Annual Research Report
  • [Publications] 佐藤 真理子: "高性能局所発汗量測定装置の開発" 繊維学会誌(発表予定).

    • Related Report
      1997 Annual Research Report
  • [Publications] Shojiro Ogawa: "Fluorescence Enhancement Observed in Tetra-aza Macrocycles by Lithium Complexation" Chemistry Letters. 709-710 (1996)

    • Related Report
      1997 Annual Research Report
  • [Publications] Toshinari Nakajima: "A New Apparatus for the Measurement of Local Sweat Rate" お茶の水女子大学人間文化研究年報. 19. 244-253 (1995)

    • Related Report
      1997 Annual Research Report
  • [Publications] 長谷川 廣子: "衣服内温湿度の季節変動に関する研究" 日本生理人類学会大会抄録集. 80-80 (1995)

    • Related Report
      1997 Annual Research Report
  • [Publications] 中島 利誠: "衣服内温湿度の変動に関する研究" 日本繊維製品消費科学会年次大会研究発表要旨. 92-93 (1995)

    • Related Report
      1997 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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