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Population Genetic Study of Indigenous Peoples of Wallacea

Research Project

Project/Area Number 10041158
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section海外学術
Research Field 人類学(含生理人類学)
Research InstitutionThe University of Tokyo

Principal Investigator

HIRAI Momoki  The University of Tokyo, Graduate School of Frontier Sciences, Professor, 大学院・新領域創成科学研究科, 教授 (60156635)

Co-Investigator(Kenkyū-buntansha) OMOTO Keiichi  Momoyama Gakuin University, Department of Literature, Professor, 文学部, 教授 (10011503)
AKAO Nobuaki  Tokyo Medical and Dental University, Department of Medicine, Lecturer, 医学部, 講師 (00126559)
MATSUMOTO Yoshitsugu  The University of Tokyo, Graduate school of Agricultural, Associate Professor, 大学院・農学生命科学研究科, 助教授 (00173922)
Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥22,200,000 (Direct Cost: ¥22,200,000)
Fiscal Year 2000: ¥6,800,000 (Direct Cost: ¥6,800,000)
Fiscal Year 1999: ¥6,800,000 (Direct Cost: ¥6,800,000)
Fiscal Year 1998: ¥8,600,000 (Direct Cost: ¥8,600,000)
KeywordsWallacea / indigenous people / population genetics / parasite / Sulawesi Island / ウオーレシア / フローレス島 / 身体計測 / インドネシア / アルフル族 / マラリア / セラム島
Research Abstract

Wallacea is a key area to elucidate the peopling of the Pacific. This area comprises the myriad islands and lies between Sundaland, the cradle of ancient Pacific stock, and Sahulland. The early inhabitants of Wallacea might have ancient connections, frequently overlaid with peoples who immigrated at later dates. There are indigenous peoples in Wallecea whose origins have been unknown. Different theories have been proposed, and many studies in various disciplines have attempted to shed light on the question of the complex origins of these peoples. We need to add substance to these arguments by studies of the genetic structure of the living populations of this area. It seems opportune to conduct Japan-Indonesia joint population genetic studies on the indigenous peoples in Wallacea to elucidate their origins. In the present study, interests are also focused on the search for genetic traits that may lead to adaptation to their environments with high prevalence of parasitic diseases.
In these three fiscal years, we have examined approximately 500 unrelated individuals who live in the research sites. To know the anthropological and population genetic characteristics of the indigenous peoples, we have conducted the following examinations: genetic markers, ovalocytosis and malaria infection, DNA plymorphisms, anthropological measurements (height, weight, span, cephalic index, etc.), somatological features, intestine parasites in feces. These three populations exhibit significantly different genetic features in terms of DNA polymorphisms. It is, therefore, interestint to analyze genetic relationships among the other indigenous populations in South East Asia.

Report

(4 results)
  • 2001 Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (18 results)

All Other

All Publications (18 results)

  • [Publications] Akao, N.: "Ocular larva migrans caused by Toxocara cati in Mongolian gerbils and a comparison of ophthalmologic findings with those produced by T. canis"J. Parasitology. 86(5). 1133-1135 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kasai, F.: "Comparative FISH mapping of the ancestral fusion point of human chromosome 2"Chromosome Research. 8. 727-735 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Dubinsky, P.: "Comparison of the sensitive screening kit with two ELISA sets for detection of anti-Toxocara antibodies"Southeast Asian J. Trop. Med. Public Health. 31(2). 394-398 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Akao, N.: "Ocular larva migrans caused by Toxocara cali in Mongolian gerbils and a comparison of ophthalmologic findings with those produced by T. canis"J. Parasilology. 86. 1133-1135 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kasai, F.: "Comparative FISH mapping of ancestral fusion point of human chromosome 2"Chromosome Research. 8. 727-735 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Dubinsky, P.: "Comparison of the sensitive screening kit with two ELISA sets for detection of anti-Toxocara antibodies"Southeast Asian J. Trop. Med. Public Health. 31. 394-398 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Akao,N.: "Ocular larva migrans caused by Toxocara cati in Mongolian gerbils and a comparison of ophthalmologic findings with those produced by T.canis."J.Parasitology. 86(5). 1133-1135 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kasai,F.: "Comparative FISH mapping of the ancestral fusion point of human chromosome 2."Chromosome Research. 8. 727-735 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Dubinsky,P.: "Comparison of the sensitive screening kit with two ELISA sets for detection of anti-Toxocara antibodies."Southeast Asian J.Trop.Med.Public Health. 31(2). 394-398 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 赤尾 信明: "感染症とその治療-新しい視点から-ウイルス・寄生虫感染症アニサキス症、今日的課題"最新医学. 54(6). 270-277 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 赤尾 信明: "リーシュマニア症"小児科臨床. 52(4). 690-692 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 赤尾 信明: "回虫症(イヌ・ネコ回虫症を含む)"小児科臨床. 52(4). 617-620 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Takayanagi, T: "New animal model for human ocular toxocariasis : Ophthalomscopic observation"British J. Ophthalmol.. 83(8). 967-972 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 赤尾信明: "最近の寄生虫感染症-その傾向と対策" 臨床検査Yearbook'98. 107. 129-137 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 赤尾信明: "ウィルスと原虫・寄生虫感染症の検査診断2-G、糸状虫" 臨床病理. 108. 247-252 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 清水早穂: "眼トキソカラ症の早期眼底所見" 眼科. 40. 947-952 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Tokuhara,M.: "Molecular cloning of human Frizzled-6." Biochem.Biophys.Res.Com.243. 622-627 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Goto,Y.: "Creeping eruption caused by a larva of the suboder Spiruruna type X." Brit.J.Dermato.139. 315-318 (1998)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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