• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Epidemiology and Control of Leishmaniasis in Central Eurasia ; A new epidemic in association with irrigation of deserts

Research Project

Project/Area Number 10041190
Research Category

Grant-in-Aid for Scientific Research (A).

Allocation TypeSingle-year Grants
Section海外学術
Research Field 寄生虫学(含医用動物学)
Research InstitutionTHE UNIVERSITY OF TOKYO

Principal Investigator

MATSUMOTO Yoshitsugu  Graduate School of Agriculture and Life Sciences THE UNIVERSITY OF TOKYO Associate Professor, 大学院・農学生命科学研究科, 助教授 (00173922)

Co-Investigator(Kenkyū-buntansha) ITO Mamoru  Central Institute for Experimental Animal Senior Scientist, 室長(研究職) (00176364)
NAGAKURA Koichi  Tokai University. School of Medicine Instructor, 医学部, 講師 (80142454)
AIKAWA Masamichi  Tokai University. School of Medicine Professor, 総合医学研究所, 教授 (90271593)
MATSUMOTO Yasunobu  Graduate School of Agriculture and Life Sciences, THE UNIVERSITY OF TOKYO Associate Professor, 大学院・農学生命科学研究科, 助教授 (90251420)
KAWAZU Shin-ichiro  Research Institute, International Medical Center of Japan Senior Scientist, 地域医療研究室, 室長(研究職)
中井 裕  東北大学, 農学部, 助教授 (80155655)
Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥25,800,000 (Direct Cost: ¥25,800,000)
Fiscal Year 2000: ¥8,800,000 (Direct Cost: ¥8,800,000)
Fiscal Year 1999: ¥7,700,000 (Direct Cost: ¥7,700,000)
Fiscal Year 1998: ¥9,300,000 (Direct Cost: ¥9,300,000)
KeywordsCutaneous Leishmaniasis / Visceral Leishmaniasis / Pathogenic protozoa / Zoonosis / Arthropod-borne Infection / Epidemiology / Irrigation of deserts / Central Eurasia / 内蔵型リーシュマニア症 / リーシュマニア症
Research Abstract

A vast area of the Central Eurasia has widely been occupied with deserts. Humans living in this sterile land have continuously struggled against natural forces to obtain water. Irrigation might bring wealth to residents and facilitate to socioeconomical development. However it also tremendously changes ecosystem in the irrigated land, suchi as changes in ecology of humans, animals, insects, and pathogenic microorganisms, resulting in new unfavorable and unexpected endemy of the diseases including leishmaniasis. Today over the areas leishmaniasis is endemic. Leishmaniasis, thus, might be one of the man-made diseases. Since 1994 we have performed epdemiological researches on leishmaniasis in some areas along the Silk Road that crosses over the Central Eurasia including Xinjiang Uygur Autonomous Region of China, the Central Asian countries, and Turkey. Leishmaniasis is widespread over the Central Eurasia, where different combination of Leishmania species, vector sandflies, and reservoir animals exists. Humans are considered to be mostly accidental hosts, although in some places, e.g.India, the disease is anthroponotic. Hence epidemic features of leishmaniasis varied among areas and therefore control measures should be different. Careful and detail epidemiological investigatrions should be needed in advance to establish effective control measures against this disease.

Report

(4 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (23 results)

All Other

All Publications (23 results)

  • [Publications] Terabe,M., et al.: "CD4+cells are indispensable for ulcer development in murine cutaneous leishmaniasis."Infection and Immunity. 68. 4574-4577 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Hatabu,T., et al.: "The production of biologically active canine interleukin-8 in gene transfected Leishmania Parasites."Procedings of the International Vet.Conference. 85-88 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Terabe, M., et al.: "CD4+ cells are indispensable for ulcer development in murine Cutaneous leishmaniasis."Infection and Immunity. 68. 4574-4577 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Hatabu, T., et al.: "The production of biologically active canine interleukin-8 in gene Transfected Leishmania parasites."Procedings of the International Vet.Conference. 85-88 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Terabe,M., et al.: "CD4+ cells are indispensable for ulcer development in murine cutaneous leishmaniasis."Infection and Immunity. 68. 4574-4577 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hatabu,T., et al.: "The production of biologically active canine interleukin-8 in gene transfected Leishmania Parasites."Procedings of the International Vet.Conference. 85-88 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Terabe, M.: "Non-ulcerative cutaneous lesion in immunodeficient mice with Leishmania amazonensis infection"Parasitology International. 48. 47-53 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Terabe. M.: "Leishmania amazonensis infection in Nude Mice"Exp. Anim.. 48(2). 119-123 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Matsumoto, Y.: "Leishumaniasis in central eurasia"Jpn. J. Trop. Med. Hyg.. 27. 59-62 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Matsumoto, Y.: "Epidemiology and Contorol of Leishmaniasis in Central Eurasia"Reserch report series (1996-1998). NO.1. -82 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Terabe,M.: "Nonulcerrative cutaneous lesion in immunodeficient mice with Leishmania amazonensis infection." Parasitol.Internal.(in press). (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Terabe,M.: "Leishmania amazonensis infection in nude mice." Exp.Animal.(in press). (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Katakura,K.: "Leishmania mini-exon genes for molecular epidemilogy of leishmaniasis in China and Fcuador" Ann.rep.Tokai univ.(in press). (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Mtsumoto,Y.: "Leishmaniasis in central eurasia." Japanese J.of Trop.Med.Hyg.(in press). (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Katakura,K.: "Diagnosis of Kala-Azar by nested PCR Based on Amplification of the Leishmania Mini-exion Gene" J.Clin.Microb.Vol.36(8). 2173-2177 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 中井 裕: "絹の道と草原の道の畜産(1)" 畜産の研究. 第52巻第10号. 1077-1084 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 中井 裕: "絹の道と草原の道の畜産(2)" 畜産の研究. 第52巻第11号. 1185-1190 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Katakura,K.: "New molecular tools for field research." Parasitology Internanational. Vol.47 supplement. 35-35 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Takeutchi,M.: "Molecular cloning of Leishmania homologue of receptors for activated C kinase cDNA of Leishmania donovani" Parasitology Internanational. Vol.47 supplement. 219-219 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Qu,JQ.: "Rapid serodiagnosis with rk39 dipstisk for visceral leishmaniasis of low endemicity in northwestern China." Parasitology Internanational. Vol.47 supplement. 227-227 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Ozensony,S.: "Recombunant k39 antigen for sero-diagnosis and epidemiology of human and canine visceral leishmaniasis in western Turkey." Parasitology Internanational. Vol.47 supplement. 227-227 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Chang,KP.: "Expression and function of ZN-protease(gp63)in Leishmania amazonesis." Parasitology Internanational. Vol.47 supplement. 219-219 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Lu,HG.: "Replacement of p36 with foreign genes for their chromosomal and extrachromosomal expression in Leishmania amazonesis." Parasitology International. Vol.47 supplement. 219-219 (1998)

    • Related Report
      1998 Annual Research Report

URL: 

Published: 1998-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi