| Project/Area Number |
10460055
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| Research Category |
Grant-in-Aid for Scientific Research (B).
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
食品科学・栄養科学
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| Research Institution | TOHOKU UNIVERSITY |
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Principal Investigator |
FUJIMOTO Kenshiro TOHOKU UNIVERSITY, GRADUATE SCHOOL OF AGRICULTURAL SCIENCE, PROFESSOR, 大学院・農学研究科, 教授 (00005620)
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| Co-Investigator(Kenkyū-buntansha) |
ENDO Yasushi TOHOKU UNIVERSITY, GRADUATE SCHOOL OF AGRICULTURAL SCIENCE, ASSOCIATE PROFESSOR, 大学院・農学研究科, 助教授 (60194049)
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| Project Period (FY) |
1998 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥5,500,000 (Direct Cost: ¥5,500,000)
Fiscal Year 2000: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1999: ¥2,200,000 (Direct Cost: ¥2,200,000)
Fiscal Year 1998: ¥2,400,000 (Direct Cost: ¥2,400,000)
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| Keywords | eicosapentaenoic acid / docosahexaenoic acid / triacylglycerol / monoacylglycerol / hydroperoxide / molecular structure / volatile aldehyde / absorption / ジアシルグリセロール / コレステロール / ラット / リンパ / 高度不飽和脂肪酸 / 脂質構造 / 脂質分子構造 / 揮発性カルボニル |
|---|
| Research Abstract |
The structures of triacylglycerols consisting of eicosapentaenoic acid and palmitic acid did not give any effect on the isomeric composition of monohydroperoxides derived from eicosapentaenoic acid formed by autoxidation Comparing the oxidative stabilities of tri-, di- and monoacylglycerols of eicosapentaenoic acid, triacylglycerol was more susceptible for autoxidation than others. Judging from the volatile aldehyde generation, the flavor stability of eicosapentaenoic acid-containing triacylglycerols was dependent on the number of eicosapentaenoic acid in a triacylglycerol molecule, i.e., trieicosapentaenoylglycerol gave the largest quantity of volatile aldehydes among all triacylglycerols. Rates and recoveries of docosahexaenoic acid given as monoacylglycerol in lymph was higher than those of triacylglycerol, diacylglycerol or ethyl esters. When docosahexaenoic acid was given to rats at a 1% level in the diet for 1 week, triacylglycerol type-docosahexaenoic acid reduced plasm and liver triacylglycerol more effectively than monoacylglycerol and ethyl ester-type docosahexaenoic acid.
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