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ANALYSIS OF THE LYTIC MECHANISM OF FILLAMENTOUS CYANOBACTERIA BY THE LITIC BACTERIA

Research Project

Project/Area Number 10460092
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Fisheries chemistry
Research InstitutionTHE UNIVERSITY OF TOKYO

Principal Investigator

MURAKAMI Masahiro  INSTITUTION, THE UNIVERSITY OF TOKYO ; DEPARTMENT, GRADUATE SCHOOL OF AGRICULTURAL LIFE SCIENCES ; TITLE OF POSITION, ASSOCIATE PROFESSOR, 大学院・農学生命科学研究科, 助教授 (70134517)

Co-Investigator(Kenkyū-buntansha) MITSUTANI Atsushi  INSTITUTION, FUKUYAMA UNIVERSITY ; DEPARTMENT, FACULTY OF ENGINEERING ; TITLE OF POSITION, ASSOCIATE PROFESSOR, 工学部・海洋生物学科, 助教授 (80309632)
Project Period (FY) 1998 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 1999: ¥3,500,000 (Direct Cost: ¥3,500,000)
KeywordsWATER-BLOOM / LYTIC BACTERIA / PROTEASE / PROTEASE INHIBITOR / CYANOBACTERIA / PEPTIDE
Research Abstract

A total of 212 heterotrophic bacterial strains were isolated from the colonies of the cyanobacteria Miocrocystis spp. collected at the Benkei Pond, Kyoto, Japan. These bacterial strains were assessed the productivity of extrace11ular protease. Although extrace11ular protease-active bacteria occupied around 50% of heterotrophic bacteria before the occurrence of the bloom of Microcytis (June) and the degradation period of the bloom (October), the proportion of them were lower, Iess then 20%, during the bloom of Microcystis (July, August and September). These results suggest the possibility that some protease inhibitors produced by Microcystis spp. actively growing in summer may inhibit the growth of extrace11ular protease-active bacteria living in the Microcystis colonies. Furthermore, sulfactin was isolated from the Bacillus SP., which was collected in the lake Kasumigaura at July, according to the antialgal activity.

Report

(3 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] Shinya Kodani: "Five new cyanobacterial peptides from water bloom materials of Lake Teganuma"FEMS Microb. Lett.. 178. 343-348 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Yusai Itou: "Anabaenopeptins G and H, potent carboxypeptidase A inhibitors from the cyanobacterium Oscillatoria agardhii"Bioorg. Med. Chem. Lett.. 9. 1243-1246 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Yusai Itou: "Oscillapeptins A to F, serine protease inhibitors from the three strains of Oscillatoria agardhii"Tetrahedron. 55. 6871-6882 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Shinya Kodani: "Occurrence and identification of UDP-N-acetylmuramyl-pentapeptide from the cyanobacterium Anabaena cylindrica"FEMS Microb. Lett.. 176. 321-325 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Masahiro Murakami: "Prenylagaramides A and B, new cyclic peptides from two strains of Oscillatoria agardhii"J. Natl. Prod.. 62. 752-755 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] M. Murakami, Y. Itou, K. Ishida, and Hee Jae Shin: "Prenylagaramides A and B, new cyclic peptides from two strains of Oscillatoria agardhii"J. Natl. Prod.. 62. 752-755 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] S. Kodani, K. Ishida, and M. Murakami: "Occurrence and identification of UDP-N-acetylmuramyl-pentapeptide from the cyanobacterium Anabaena cylindrica"FEMS Microb. Lett.. 176. 321-325 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Y. Itou, Hee Jae Shin, K. Ishida, and M. Murakami: "Oscillapeptins A to F, serine protease inhibitors from the three strains of Oscillatoria agardhii"Tetrahedron. 55. 6871-6882 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Y. Itou, S. Suzuki, K. Ishida, and M. Murakami: "Anabaenopeptins G and H, potent carboxypeptidase A inhibitors from the cyanobacterium Oscillatoria agardhii, Bioorg."Med. Chem. Lett.. 9. 1243-1246 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] S. Kodani, S. Suzuki, K. Ishida, and M. Murakami: "Five new cyanobacterial peptides from water bloom materials of Lake Teganuma"FEMS Microb. Lett. 178. 343-348 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Shinya Kodani: "Five new cyanobacterial peptides from water bloom materials of Lake Teganuma"FEMS Microb.Lett.. 178. 343-348 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Yusai Itou: "Anabaenopeptins G and H,potent carboxypeptidase A inhibitors from the cyanobacterium Oscillatoria agardhii"Bioorg.Med.Chem.Lett.. 9. 1243-1246 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Yusai Itou: "Oscillapeputins A toF,serine protease inhibitos from the three strains of Oscillatoria agardhii"Tetrahedron. 55. 6871-6882 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Shinya Kodani: "Occurrence and identification of UDP-N-acetymuramyl-pentapeptide from the cyanobacterium Anabaena cylindrica"FFMS Microb.Lett.. 176. 321-325 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Masahiro Murakami: "Prenylagaramides A and B,new cyclic peptides from two strains of Oscillatoria agardhii"J,Natl.Prod.. 62. 752-755 (1999)

    • Related Report
      1999 Annual Research Report

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Published: 1999-04-01   Modified: 2016-04-21  

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