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Radiation Risk Estimate and Risk-Benefit Analysis Following Breast Cancer Screening Using Mammography

Research Project

Project/Area Number 10470192
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionOita University of Nursing and Health Sciences

Principal Investigator

KUSAMA Tomoko  Faculty of Nursing, Oita University of Nursing and Health Sciences, Professor, 看護学部, 教授 (50134523)

Co-Investigator(Kenkyū-buntansha) AKAHANE Keiichi  Faculty of Nursing, Oita University of Nursing and Health Sciences, Research Associate, 看護学部, 助手 (80202521)
BAN Nobuhiko  Faculty of Nursing, Oita University of Nursing and Health Sciences, Assistant Professor, 看護学部, 講師 (70251220)
KAI Michiaki  Faculty of Nursing, Oita University of Nursing and Health Sciences, Professor, 看護学部, 教授 (10185697)
Project Period (FY) 1998 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 1999: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1998: ¥2,700,000 (Direct Cost: ¥2,700,000)
KeywordsMAMMOGRAPHY / BREAST CANCER RISK / MASS SCREENING / X-RAY / CR
Research Abstract

In Oita prefecture, we investigated whether screening mammography (SMG) is used for detecting early breast cancer, and found that SMG is carried our in 8 medical facilities among 14 facilities which preform primary mass screening. In each, the average does to breast tissue was less than 3mGy which is guidance level recommended by IAEA. However, there was large variation among the facilities. The Maximum dose was 4.25 time higher than the minimum. The doses may depended not only upon age at diagnosis but also a type of record in SMG, which the dose in film-screen record was 2.4 times higher than in CR (Computed Radiography).
Average glandular doses to breast were based on determination of entrance skin exposure (ESE) to the breast of a known thickness. The relation between the ESE and average glandular dose was obtained using the Monte Carla method with the EGS4 code. This method enables us to look at the effect of any breast composition.
We investigated the relation between the dose and the image quality in SMG using a RMI 156 phantom in order to optimize the breast dose. Image evaluation was carried out by 8 radiation technicians and one radiologist according to the guideline of the Japan Association of Breast Cancer Screening. The total evaluation of performance in CR was lower than in film-screen whereas the dose in film-screen record was 2.4 times higher than in CR. If the dose increase in CR, a better performance did not appear to be increased. The various factors which control the relation between the dose and the image quality will be need to make clear.
We analyzed breast cancer incidence data of atomic bomb survivors in Hiroshima and Nagasaki using a two-stage stochastic model and found that our model can explain the incidence trend due to birth cohort effect.

Report

(3 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report

URL: 

Published: 1998-04-01   Modified: 2016-04-21  

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