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Study on Fate and Ecotoxicity Evaluation of Hard-decompositive Toxic Chemicals in Ecosystems

Research Project

Project/Area Number 10480127
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental dynamic analysis
Research InstitutionOkayama University

Principal Investigator

AOYAMA Isao  Research Institute for Bioresources, Okayama University, Prof., 資源生物科学研究所, 教授 (10026239)

Co-Investigator(Kenkyū-buntansha) LUO Rong  Research Institute for Bioresources, Okayama University, Assistant Prof., 資源生物科学研究所, 助手 (10284093)
OKAMURA Hideo  Research Institute for Bioresources, Okayama University, Assistant Prof., 資源生物科学研究所, 助手 (90253020)
MURAMOTO Shigeki  Research Institute for Bioresources, Okayama University, Associate Prof., 資源生物科学研究所, 助教授 (50033121)
Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥10,100,000 (Direct Cost: ¥10,100,000)
Fiscal Year 2000: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1999: ¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 1998: ¥4,700,000 (Direct Cost: ¥4,700,000)
Keywordshard-decompositive chemicals / conservative chemicals / toxic chemicals / eotoxicity evaluation / fate / interactive effect / surface active agents / leachate from industrial wastes landfill / 生態毒性 / 河川における流下過程 / 吸着特性 / 農薬 / 重金属 / ミジンコの運動量解析 / 農薬の流出 / 相関解析
Research Abstract

Pullution of ecosystems by dioxine, agricultural chemicals etc. has become recognized to be an global and very serious issues on a matter of life or death of mankind.
The object of this study is to analyze the fate and to evaluate ecotoxicity toxic chemicals released into environments. We clarified the origin of toxic chemicals, the fate of chemicals in an aquatic ecosystem, ecotoxicity, antifouling chemicals in the Inland Sea of Seto and interaction effects of chemicals.
At first, we took up the landfill leachate of industrial wastes and evaluated cytotoxicity, genetic toxicity, endocrine disruption. Cytotoxicity for swimming inhibition of Daphnia magna was determined for all sampling cites of leachates. We determined genetic toxicity from a few sampling cites. However, endocrine disrupting effect was determined from 40 fold concentrated leachates of almost all sites. We examined the fate of toxic organic-chemicals along a river in Okayama Prefecture. Hard-dissolved chemicals by water w … More as adsorbed to river sediments and existed more in sediments than in water. Therefore, the toxicity of sediments was stronger than that of water.
The quantitative structure-activity relationship analysis was performed for 13 kinds of Chlorophenols using Saccharomyces cerevisiae. The relationships were established between EC50's and a number of molecular proparties. When molecular parameters were used alone, there were high correlations for octanol-water partition coefficient, These results showed that QSAR is a very effective tool in predicting the toxicity of chlorophenols to Saccharomyces cerevisiae as well as to other organisms. Interactive effects among heavy metals and agricultural chemicals, Imidacloprid, were investigated using Daphnia magna. Synergistic and antagonistic effects were observed for heavy metals. Antagonistic and additive effects were observed for Imidacloprid and heavy metals. We could get a high correlation between a traditional swimming inhibition test and a newly developed mobility inhibition test using D. magna. Recently a new antifouling agent Irgarol 1051 has been used. It was found that the Inland Sea of Seto has already been polluted by the new antifouling agent. The decomposed chemicals M1 of irgarol 1051 was also determined in the sea water. The toxicity of the daughter chemicals was weaker than the parent chemicals, but it had hard disintegration. It suggested that the daughter chemicals M1 should be taken care for environmental pollution of sea water in the long run. Less

Report

(4 results)
  • 2001 Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (48 results)

All Other

All Publications (48 results)

  • [Publications] H.Okamura, I.Aoyama et al.: "Microbial Adosorption of Cyanazine and Metolachlor"J. Environmental Sci. and Health. B33・1. 1-15 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 羅 栄, 青山 勳, 岡村秀雄: "酵母Scharomyces cerevisiaeを用いた底質中の有機有害物質の毒性評価"水環境学会誌. 21・4. 244-249 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 青山 勳, 岡村秀雄, 羅 栄: "産業廃棄物埋め立て浸出水の生態毒性評価"環境技術. 27・5. 330-334 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H.Okamura, I.Aoyama: "Halogenation and Toxicity of the Biodegradation Products of a non-ionic surfactant, nonyphenol ethoxylate"Environmental Toxicology and Chemistry. 17・4. 650-654 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 青山 勳: "内分泌撹乱化学物質の生態影響評価"日本農薬学会誌. 24. 105-109 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Muramoto, F.Tezuka, W.Agata: "Effects of Anionic Surface Active Agents on the Uptake of Aluminium by Cyprus alternifolius L. Exposed to Water Containing High Levels of Al"Bull.Environ.Contam.Toxicology. 64. 122-129 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Isao Aoyama(分担執筆): "Comparative Evaluation of Environmental Toxicants"KODANSYA SCIENTIFIC LTD. 307 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 青山 勳(分担執筆): "検証「環境ホルモン」"青木書店. 274 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Okamura, I. Aoyama et. al.: "Microbial Adsorption of Cyanizine and Metolachlor"J. Environmental Sci. and Health. B33・1. 1-15 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] R. Luo, I. Aoyama and H. Okamura.: "Evaluation of Toxicity of Organic Toxic Matter in Sediments Using Yeast Saccharomyces cerevisiae"J. Water Environment. 21・4. 244-249 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] I. Aoyama, H. Okamura, R. Luo and et. al.: "Ecotoxicity Evaluation of Land Fill Leachates"J. Environmental Technology. 27・5. 244-249 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Okamura, I. Aoyama and et. al.: "Halogenation and Toxicity of the Bio Degradation Products of a Nonionic Surfactant, Nonyphenyl Ethoxylate"Environmental Toxicology and Chemistry. 17・4. 650-654 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Okamura, R. Luo, I. Aoyama and et. al.: "Ecotoxicity Assessment of Landfill Leachates Using a Battery of Bioassay and Toxicity Characterization of the Leachates"Jpn Journal of Environmental Toxicology. 1・1. 43-50 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] I. Aoyama: "Ecotoxicity Evaluation and Bioassay"J. of the Japan Society of Waste Management Experts. 9・5. 358-367 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Okamura, I. Aoyama and D. Liu.: "Fate and Ecotoxicity of the New Antifouling Agent Irgarol 1951 in Aquatic Environment"J. Environmental Technology. 28・5. 315-319 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Okamura, M. Omori, R. Luo and I. Aoyama: "Application of Short-term Bioassay Guided Chemical Analysis for Water Quality Agricultural Land Run-off"The Science of the Environment. 234. 223-231 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] D. Liu, G. J. Pacepavicius, H. Okamura, Isao Aoyama and et. al.: "Mercuric Chloride-catalyzed Hydrolysis of the New Antifouling Compound Irgarol 1051"Water Research. 33・1. 155-163 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] D. Liu, G. J. Pacepavicius, H. Okamura, Isao Aoyama and et. al.: "Survey for the Occurrence of the New Antifouling Compound Irgarol 1051 in the Aquatic Environment"Water Research. 33・12. 2833-2843 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] I. Aoyama: "Ecotoxicity Evaluation of Endocrine Disrupting Chemicals"J. Japan Agricultural Chemicals. 24. 105-109 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] T. Akasi, T. Tsukihara, R. Luo and I. Aoyama: "Effect of Heavy Metals on the Growth of Phanerochaete chrysosporium"J. Environmental Technology. 28・4. 271-275 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Okamura, I. Aoyama, D. Liu and et.al.: "Photodegradation of Irgarol 1051 in Water"J. Environmental Science. B34・2. 225-238 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] A. Kungolos, I. Aoyama and S. Muramoto: "Toxicity of Organic and Inorganic Mercury to Saccharomyces cerevisiae"Ecotoxicology and Environmental Safety. 43・2. (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Okamura, I. Aoyama and et. al.: "Phytotoxicity of the Antifouling Compound Irgarol 1051 and a Major Degradation Product"Marie Pollution Bulletin. 40. 754-763 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Okamura, I. Aoyama, D. Liu and et. al.: "Fate and Ecotoxicity of the New Antifouling Compound Irgarol 1051 in the Aquatic Environment"Water Research. 34. 3523-3530 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M. Piao, H. Okamura, R. Luo and I. Aoyama: "Interactive Effect of Heavy Metals and Pesicide on Daphnia magna"Japan Journal of Environmental Toxicology. 3・1. 23-32 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Muramoto, T. Maitani and I. Aoyama: "Distribution Characteristics of Acid Dissolved Trace Metals of Suspended Particulate Matter"J. Environmental Science. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] A. Kungolos and I. Aoyama: "Quantitative Structure-Activity Relationships for the Effect of Chlorophenols on Saccharomyces cerevisiae"Journal of Environmental Toxicology. (in press).

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] I. Aoyama, (Co-author): "Bioassay Using Micro-organisms. in Risk Management of Water Environment"Kodansya Scientific Ltd.. 362 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] I. Aoyama, (Co-author): "Ecotoxicity Assessment and Bioassay of Toxic Chemicals. in Comparative Evaluation of Environmental Toxicants"KODANSHA SCIENTIFIC LTD.. 307 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] I. Aoyama, (Co-author): "Chemical Substances and Ecosystems -Ecotoxicology- in Verification "Environmental Hormnen""Aoki Book Co.. 274 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] I. Aoyama, (Co-author): "Microbiotest in Japan, in New Microbiotests for Routine Toxicity Screening and Biomonitoring"Kluwer Academic/Plenum Publishers, New York. 550 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Muramoto et.al.: "Effects of anionic surfactants on the uptake of aluminium by Cyperus alternifolis L.exposed to water containg high levels of alminium"Bull.of Environmental Contamination and Toxicology. 64. 122-129 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] H.Okamura and dl.Aoyama: "Ohytotoxicity of the antifouling compond Irgarol 1051 and a major degradation product"Marine Polution Bulletin. 40. 754-763 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] I.Aoyama: "New Microbiotests for Routine Toxcity Screening and Biomonitoring"Kluwer Academic/Plenum Publishers,New York. 550 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 青山 勲: "内分泌撹乱作用物質の生態影響評価"日本農薬学会誌. 第24号. 105-109 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Aoyama, I.: "Toxicity of Organic and Inorganic Mercury to Saccharomyces cerevisiae"Ecotoxicology and Environmental Safety. 43. 149-155 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Okamura, H.: "Application of short-term bioassay guided chemical analysis for water quality of agricultural land runoff"Sci. Total Environ.. 234. 223-231 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Okamura, H.: "Photodegradation of Irgarol 1051 in water"J. Environ. Aci. Health. B34(2). 225-238 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 岡村 秀雄: "水環境における新規防汚剤Irgarol 1051の運命と生態毒性"環境技術. 28(5). 315-319 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 青山 勲: "検証「環境ホルモン」(化学物質と生態系-エコトキシコロジー)"青木書店. 274 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Aoyama, I.: "Kluwer Academic/Plcnum Publishers"Toxicity testing in Japan and the use of Toxkit microbiotests.. (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 羅栄: "酵母Saccharomyces cerevisiaeを用いた底質中の有害化学物質の毒性評価" 水環境学会誌. 21・4. 244-249 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 青山勲: "産業廃棄物埋立浸出水の生態毒性評価" 環境技術. 27・5. 330-334 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] MAKI,Hideaki: "Halogenation and toxicity of the biodegradation products of a nonionic sulfactant.nonyphenol ethoxylate." Env.Toxicol. and Chem.17・4. 650-654 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 岡村秀男: "産業廃棄物埋立浸出水の生態毒性評価および毒性キャラクタリゼーション" 環境毒性学会誌. 1・1. 43-50 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] LIU.Dickson: "Microbial adsorption of cyanazine and metolachlor" J.Eniviron.Sci.Health. B33・1. 1-15 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 青山勲: "水環境のリスク管理" 講談社サイエンティフィック, 362 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] AOYAMA,Isao: "Comparative Evaluation of Environmental Toxicant" KODANSHA SCIENTIFIC LTD., 307 (1998)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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