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Investigation of Intelligent Network Topology by Mimicking the Fault-tolerant Network Structure of Metabolic Pathways

Research Project

Project/Area Number 10555128
Research Category

Grant-in-Aid for Scientific Research (B).

Allocation TypeSingle-year Grants
Section展開研究
Research Field 情報通信工学
Research InstitutionKyushu Institute of Technology

Principal Investigator

OKAMOTO Masahiro  Dept.of Biochemical Engineering & Science, Kyushu Institute of Technology, Associate Professor, 情報工学部, 助教授 (40211122)

Co-Investigator(Kenkyū-buntansha) YAMAKAWA Takeshi  Dept.of Control Science & Engineering, Kyushu Institute of Technology, Professor, 情報工学部, 教授 (00005547)
EGUCHI Yukihiro  Mitsui Knowledge Industry, Head of Research Institute, 総合研究所, 所長
OIE Yuji  Dept.of Computer & Electrical Engineering, Kyushu Institute of Technology, Professor, 情報工学部, 教授 (50167293)
MIZOGUCHI Yoshihiro  Dept.of Control Science & Engineering, Kyushu Institute of Technology, Associate Professor, 情報工学部, 助教授 (80209783)
久原 哲  九州大学, 大学院・農学研究院, 教授 (00153320)
Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥12,700,000 (Direct Cost: ¥12,700,000)
Fiscal Year 2000: ¥1,700,000 (Direct Cost: ¥1,700,000)
Fiscal Year 1999: ¥3,900,000 (Direct Cost: ¥3,900,000)
Fiscal Year 1998: ¥7,100,000 (Direct Cost: ¥7,100,000)
Keywordsnetwork topology / development of functional device / fault-tolerant / metabolic pathway / traffic control of telecommunication / simulator capture
Research Abstract

In spite of taking the continuous perturbations, metabolic pathways can keep the homeostatic capability of biochemical information. They may be fault-tolerant against external perturbations and take multi-compensating structure. By mimicking these features as for the network topology of metabolic pathways, we can propose the intelligent fault-tolerant network topology of telecommunications. We have implemented an efficient, user-friendly "biosimulator" named BEST-KIT (Biochemical Engineering System analyzing Tool-KIT) for analyzing a large scaled nonlinear reaction network such as metabolic pathways. The BEST-KIT mainly consists of two kinds of modules, "MassAction" and "EnzymeKinetics". In this study, we have developed new module, "MassAction++", which can construct and analyze reaction scheme represented by both mass action law (mass balance) and approximated velocity functions of enzyme kinetics at steady state. All modules in BEST-KIT are developed in Java applet style, and can be carried out on the "any" platform machine through the web browser. The "MassAction++" was developed by Java applet style and can save data related on the constructed reaction scheme and time course data on the client disk space and can load it to the web browser.

Report

(4 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (9 results)

All Other

All Publications (9 results)

  • [Publications] K.Sakuraba et al.: "BEST-KIT : Development of Biochemical Engineering System Analyzing Tool-Kit"Proceedings of 1^<st>. Intl.Conf.on System Biology (ICSB2000). 124-129 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Kenji Sakuraba, Jun-ichi Ueno, Masakazu Mori, Kouji Tanaka, Jun Yoshimura, Masahiro Okamoto: "BEST-KIT : Development of Biochemical Engineering System Analyzing Tool-KIT."Proc.of the 1^<th>.Intl.Conf.on System Biology (ICSB2000). 124-129 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Yoshitaka Isobe, Tetsuji Nishizono, Jun Yoshimura, Kenji Sakurabe, Masahiro Okamoto: "Development of Web-based Simulation System for Real-time Optimal Control in Bio-process System."Proc.of the 28^<th>.SICE Symp. on Intelligent Systems. (in Japanese). 63-68 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] K.Sakuraba et al.: "BEST-KIT : Development of Biochemical Engineering System Analyzing Tool-Kit"Proceedings of 1^<st>.Intl.Conf.on System Biology (ICSB2000). 124-129 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] D.Tominaga et.al.: "Nonlinear numerical optimization technique based on genetic algorithm for inverse problems"Proc.of the German Conference on Bioinformatics (GCB'99). 1. 127-140 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] M.Okamoto et al.: "Biochemical Neuron: Hardware implementation of functional devices by mimicking The natural intelligence such as metabolic control systems"Computers and Electric.Engng.. 25. 421-438 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] D.Tominaga & M.Okamoto: "Design of canonical model describing complex nonlinear dynamics" Proc.Of7th.Intl.Conf.on computer applications in biotechnol. 1. 85-90 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 岡本正宏: "ナチュラルインテリジェンスに学ぶ知的通信技術:生体内代謝経路を用いた情報通信の恒常性探索と機能素子の探索" SCAT Technical J.21. 2-11 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] M.Okamoto et al.: "Biochemical Neuron:Hardware implementation of functional devices by mimicking The natural intelligence such as metabolic control systems" Intl.J.Computers and Electric Engng.in press. (1999)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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