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Development of in vitro exposure setups for experiments on nonthergal biological effects of modulated high intensity radiofrequency electromagnetic fields.

Research Project

Project/Area Number 10555129
Research Category

Grant-in-Aid for Scientific Research (B).

Allocation TypeSingle-year Grants
Section展開研究
Research Field 情報通信工学
Research InstitutionTOKYO METROPOLITAN UNIVERSITY

Principal Investigator

TAKI Masao  Graduate School of Engineering, Tokyo Metropolitan University, Professor, 大学院・工学研究科, 教授 (60145670)

Co-Investigator(Kenkyū-buntansha) WASHIZU Masao  Graduate School of Engineering, Kyoto University Professor, 大学院・工学研究科, 教授 (10201162)
MIYAKOSHI Junji  Graduate School of Medicine, Kyoto University Associate Professor, 大学院・医学研究科, 助教授 (70121572)
WATANABE Soichi  Communication Research Laboratory, Ministry of Public Management, Home Affairs, Posts and Telecommunications Senior Researcher, 通信総合研究所, 主任研究官
Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥12,700,000 (Direct Cost: ¥12,700,000)
Fiscal Year 2000: ¥2,700,000 (Direct Cost: ¥2,700,000)
Fiscal Year 1999: ¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 1998: ¥7,200,000 (Direct Cost: ¥7,200,000)
Keywordselectromagnetic / biological effects / in vitro / exposure system / microwaves / 細胞 / マイクロ波 / 高周波 / 電磁界
Research Abstract

1 We developed microwave exposure systems for experiments on biological effects of microwaves in vitro. Strong internal field in the athermal condition was required as the special interest in this research was the health effect of localized exposure on the head by mobile telephone devices.
2 Comb-type microelectrocles were fabricated. Cells were placed between the electrocles. A technique to place cells at proper positions was developed using a mask. This electrode system achieved the high intensity exposure on cells.
3. A circular waveguide exposure system was developed. This system could expose a large number of cells in the required condition. The exposure assessment of this setup was made by means of numerical as well as experimental approaches.
4 Further developments were made to improve the exposure system. A rectangular waveguide with a transversal slit was designed. This setup achieved very high intensity exposure of 30 W/kg for the input power of 1W.

Report

(4 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (33 results)

All Other

All Publications (33 results)

  • [Publications] 渡邊聡一: "携帯電話のin vivoばく露装置と動物実験"電子情報通信学会論文誌B. E84-A. 19-28 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Kanako Wake: "Analysis of induced currents in a rat exposed to 50 Hz linearly and circularly polarized magnetic fields"Bioelectromagnetics. Vol.21. 354-363 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Yoshiaki Watanabe: "FDTD analysis of microwave hearing effect"IEEE Trans.Microwave Theory and Technique. Vol.48. 2126-21* (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] G-R Ding,: "Increase in hypoxanthine-guanine phosphoribosyl transferase gene mutations by exposure to electric field"Life Sciences. 68. 1041-1046 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] G.Tsurita,: "Biological and morphological effects on the brain after exposure of rats to a 1439 MHz TDMA field"Bioelectromagetics. Vo.21. 364-371 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 丸山祥史: "スリット導波管を用いた細胞用マイクロ波曝露装置"電子情報通信学会技術研究報告 環境電磁工学(EMCJ). (発表予定). (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] S.Watanabe and M.Taki: "In vivo exposure setups for animal studies on biological effects of electromagnetic exposure from cellular telephones (in Japanese)"Trans IEICE. Vol.J84-B, No.1. 19-28 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] G-R Ding, K.Wake, M.Taki, J.Miyakoshi: "Increase in hypoxanthine-guanine phosphoribosyl transferase gene mutations by exposure to electric field"Life Sciences. Vol.68. 1041-1046 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Yoshiaki Watanabe, Toshiyuki Tanaka, Masao Taki, Soichi Watanabe: "FDTD analysis of microwave hearing effect"IEEE Trans. Microwav. Theory Tech.. vol.48, no.11. 2126-2132 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] K.Wake, T.Tanaka, and M.Taki: "Analysis of induced currents in a rat exposed to 50-Hz linearly and circularly polarized magnetic fields"Bioelectromagnetics. Vol.21, No.5. 354-363 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] G.Tsurita, H.Nagawa, S.Ueno, S.Watanabe, M.Taki: "Biological and morphological effects on the brain after exposure of rats to a 1439 MHz TDMA field"Bioelectromagetics. Vol.21, No.5. 364-371 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] M.Taki: "Biological effects of electromagnetic fields and health risks"J.IEICE. Vol.82, No.6. 572-579 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Masao Taki: "Health Protection Guidelines for Electromagnetic Field Exposures (in Japanese)"Journal of Plasma and Fusion Research. Vol.75, No.1. 45-49 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Soichi Watanabe and Masao Taki: "An Improved FDTD Model for the Feeding Gap of a Thin-Wire Antenna"IEEE Microwave and Guided Wave Letters. Vol.8, No.4. 152-154 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] K.Wake, M.Kawasumi, T.Tanaka, M.Taki: "Induced current density distribution in a human related to magnetophosphenes (in Japanese)"Trans.IEE Japan. vol.118-A, no.7/8. 806-811 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Yoshihumi Maruyama, Kanako Wake, Soichi Watanabe, Masao Taki: "In vitro exposure setup using a rectangular waveguide with a transversal slit"Technical Report of IEICE, EMCJ. (to be presented, in Japanese). (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 渡辺聡一: "携帯電話のin vivoばく露装置と動物実験"電子情報通信学会論文誌B. E84-A. 19-28 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kanako Wake: "Analysis of induced currents in a rat exposed to 50 Hz linearly and circularly polarized magnetic fields"Bioelectromagnetics. Vol.21. 354-363 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Yoshiaki Watanabe: "FDTD analysis of microwave hearing effect"IEEE Trans.Microwave Theory and Technique. Vol.48. 2126-2132 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] G-R Ding: "Increase in hypoxanthine-guanine phosphoribosyl transferase gene mutations by exposure to electric field"Life Sciences. 68. 1041-1046 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Masao Taki: "Search for phosphenes induced by exposure to radio-frequency fields with ELF amplitude modulation"Bioelectromagnetics Society 22^<nd> Annual Meeting. 83-84 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 丸山祥史: "スリット導波管を用いた細胞用マイクロ波曝露装置"電子情報通信学会技術研究報告 環境電磁工学. (発表予定). (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] 多氣昌生: "高周波電磁界の生体作用"医用電子と生体工学. 37・特別号. 42 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 斎藤正男: "電波の生体影響と健康リスク"電子情報通信学会誌. 82-6. 572-579 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Masao Taki: "Exposure setup for in vitro experiment on biological effects of microwaves"26^<th> General Assembly of the International Union of Radio Science. 863 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Soichi Watanabe: "An experimental study on the dependence of local SARs on a human ear during exposure to MW from a cellular telephone"1999 International Symposium on Electromagnetic Compatibility. 341-344 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Junji MIYAKOSHI: "Effects of high-density extremely low frequency magnetic field on sister chromatid exchange in mouce m5S cells"Mutation Research. 440. 189-194 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Soichi Watanabe: "An improved FDTD Model for the feeding gap of a thin-wire antenna" IEEE Microwave and Guided Wave Letters. 8(4). 152-154 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Soichi Watanabe: "Power absorption of rats in a 1.439 GHz near-field exposure system." 20th Annual meeting of Bioelectromagnetics Soc.257-257 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Junji Miyakoshi: "Enhanced NOR-1 gene expression by exposure of Chinese hamster cells to high-density 50Hz magnetic fields." Molecular and Cellular Biochemistry. 181. 191-195 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Junji Miyakoshi: "Suppression of high-density magnetic field (400mT at 50Hz)-induced mutations by wild-type p53 expression in human osteosarcoma cells." Biochemical and Biophysical Research Communications. 243. 579-584 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Taktoki Yamamoto: "Molecular surgery of DNA using restriction enzymes" Nano to Macroscale Science and Technology through Microsystems. 38-38 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Masao Washizu: "Electrostatic actuation of liquid droplets for micro-reactor applications" IEEE Transaction IA. 34(4). 732-737 (1998)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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