| Project/Area Number |
10557160
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| Research Category |
Grant-in-Aid for Scientific Research (B).
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | TOKYO DENTAL COLLEGE |
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Principal Investigator |
INOUE Takashi Tokyo Dental College, Department of Pathology, Associate Professor, 歯学部, 助教授 (20125008)
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| Co-Investigator(Kenkyū-buntansha) |
ABIKO Yoshihiro Hokkaido Health Science Uni, Dept of Oral Pathology, Associate Professor, 歯学部, 助教授 (90260819)
YOSHINARI Masao Tokyo Dental College, Dept of Dental Mat. Science, Associate Professor, 歯学部, 助教授 (10085839)
SHIMONO Masaki Tokyo Dental College, Department of Pathology, Professor, 歯学部, 教授 (00085771)
OOTHSKA Yoshiro Thukuba, Department of Material Reseach, Chief, 筑波超材研, 専門室長
KISHI Yoshiaki KANAGAWA Dental College, Department of Anatomy, Associate Professor, 歯学部, 助教授 (60084779)
大塚 芳郎 日本真空技術(株), 筑波超材料研, 専門室長
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| Project Period (FY) |
1998 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥12,300,000 (Direct Cost: ¥12,300,000)
Fiscal Year 2000: ¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 1999: ¥3,900,000 (Direct Cost: ¥3,900,000)
Fiscal Year 1998: ¥6,100,000 (Direct Cost: ¥6,100,000)
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| Keywords | Fibrointegration / Dental Implant / Fibroblast / pore-size / in vitro / in vivo / Fibrointegration / pore-size / Titanium / Sharpy fiber / Fibro-integration / Dental implant / fibroblast / pore size / SEM / pori-implautitis |
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| Research Abstract |
The success or failure of the dental implant depends on the acquisition of the firm osseointegration. Eventhough, firm osseointegration was achieved, the defense mechanism of soft tissue around the implant does not exist further than the natural tooth and this is the reason why peri-implantitis is easy to be induced and always has the danger of the falling. From this point of view, the firm attachment of the connective tissue under the epithelium by fibrointegrated implant raised by this project seems to be important in order to prevent the bone resorption. The retrieval was advanced on the surface given to the implant cervix in order to artificially make the sharpy fiber. It had the ruggedness of about 3 μm as a surface shape on the implant surface, and information of being effective in order to form the organization that the implant as an aperture with the hole over 50 μm is sharpy fibers was obtained.
On the surface quality with the effect in the fibrous attachment, the modification was studied. Surface design considering the surface charge was tried. It was possible that it conducted ion implantation processing (Ca+, N+, F+), anodization, titania low temperature thermal spraying processing, ion plating processing (TiN, Alumina), abrasion resistant surface treatment of ion beam mixing processing (Ag, Sn, Zn, Pt) to the pure titanium plate of the specularity and obtains basic data.
The necessity of the development of the artificial saliva which will stop application of gargling and mouth rinsing medicine, induction of the antibody which stops the bacteria adhesion or bacteria adhesion including clinical application in future is indicated.
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