| Project/Area Number |
10557200
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
矯正・小児・社会系歯学
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| Research Institution | National Institute of Infections Diseases |
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Principal Investigator |
HARADA Nobuhiro National Institute of Infections Diseases, Dept. of Org. science, Director, 口腔科学部, 部長 (70180916)
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| Co-Investigator(Kenkyū-buntansha) |
INABA Daisuke Iwate Medical University, Dept. of Preveertive Dentistry, Associate Professor, 歯学部, 助教授 (90146085)
YOSHIMITSU Masami Iwate Medical University, Dept. of Preveertive Dentistry, Professor, 歯学部, 教授 (80092451)
ETO Akoko National Institute of Infections Diseases, Dept. of Org. science, Researcher, 口腔科学部, 研究員 (50291125)
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| Project Period (FY) |
1998 – 2001
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| Project Status |
Completed (Fiscal Year 2001)
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| Budget Amount *help |
¥10,300,000 (Direct Cost: ¥10,300,000)
Fiscal Year 2001: ¥2,300,000 (Direct Cost: ¥2,300,000)
Fiscal Year 2000: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 1999: ¥2,600,000 (Direct Cost: ¥2,600,000)
Fiscal Year 1998: ¥2,900,000 (Direct Cost: ¥2,900,000)
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| Keywords | elderly / dental caries / saliva / 唾液 / 連鎖球菌 / 肺炎 |
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| Research Abstract |
We investigated correlation between health status and health-promoting factors in the oral region. We assumed that health-promoting factors in the oral region would play an important role to prevent a man from infecting serious diseases through respiration and feeding. We performed oral examination of elderly people who keep their own teeth of 20 at the age of 80 (we call them 8020 people), according to WHO oral examination procedures. In detail, composition of oral bacterial flora, saliva constituent, saliva volume, salivary buffering were examined. Blood constituent, diet convention, athletic capacity were studied to clarify their relation with oral health status. Bacterial species studied were Candida albicans, Streptococcus mutans. Streptococcus sobrinus, Streptococcus pneumoniae, Psedomonos aeruginosa, Staphylococcus aureus. Haemophilias oarainfluenzae, etc. Furthermore, we put our attention on antibacterial peptide in saliva, such as defensin and histatin, and did quantitative analysis of these peptides.
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