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Studies on Stochastic Machine based on Stochastic Resonance and Bio-molecular Machine

Research Project

Project/Area Number 10558130
Research Category

Grant-in-Aid for Scientific Research (B).

Allocation TypeSingle-year Grants
Section展開研究
Research Field Biomedical engineering/Biological material science
Research InstitutionNational Graduate Institute for Policy Studies

Principal Investigator

MATSUURA Hiroyuki  National Graduate Institute for Policy Studies, Associate Professor, 政策研究プロジェクトセンター, 助教授 (30262116)

Co-Investigator(Kenkyū-buntansha) NAKANO Masahiro  University of Occupational Environmental Health, Dep. of Biomedical and Environmental Technology, Associate Professor, 医学部, 助教授 (70141744)
IMACHI Kou  University of Tokyo, Graduate school of Medicine, Professor, 大学院・医学系研究科, 教授 (10010076)
FUJIMASA Iwao  National Graduate Institute for Policy Studies, Dep. of Policy Studies, Professor, 大学院・政策研究科, 教授 (30010028)
Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥7,100,000 (Direct Cost: ¥7,100,000)
Fiscal Year 2000: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 1999: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1998: ¥4,700,000 (Direct Cost: ¥4,700,000)
Keywordsstochastic resonance / actin myosin system / molecular machine / stochastic machine / Brownian motion / Nyquist Theorem / thermal noise / SN ratio / 閾値 / 確率共鳴機械 / ナノマシンシステム / 分子機械 / 散逸系 / 量子ゆらぎ / トンネル効果 / 筋肉組織 / 分子間力ギア / Stochastic Machine / レーザーピンセット / ゆらぎ
Research Abstract

The ultimate goal of this study is to create an energy transformation device (micro actuator) that functions in living bodies. Aiming this, we built a micro actuator and analyzed its motion, energy transformation mechanism in the water. To develop studies on conventional vibrating artificial muscles, we thought of muscle as biomolecular machine. This new model of molecular machine as Actin Myosin System named Stochastic Inclined Rods model (SIRM), whose energy of motion is supplied from random noise and always moves to one direction, has been proposed. SIRM has a simple structure, which is composed of an inclined spring, myosin head, and bundle of rods. In an open system, the myosin head works as a resonator of random noise, which accepts the energy through a resonance. It is shown that the inclined rod and a spherical shape of G-actin are very important elements for a purpose of breaking symmetric vibration of stochastic resonance and generating the one directional motion. Although the potentials of G-actin and the myosin head are completely symmetrical, the structure of the actin myosin system makes it possible to move asymmetry. We have got the SIRM's solution by two method (perturbative methods and numericalones)

Report

(4 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (51 results)

All Other

All Publications (51 results)

  • [Publications] Matsuura H,Nakano M: "Actin myosin systems based on the stochastic resonance"Biomedical soft computing and Human Science, Biomedical fuzzy system association. 4(1). 23-31 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 岩崎清隆,松浦弘幸,井街宏,中野正博 他: "X線回折実験によるJellyfish弁の弁葉破壊挙動の解明を目指した基礎的検討"第10回バイオエンジンアリング講演論文集. 97(2). 181-182 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H,Nakano M: "stochastic dynamics of molecular machine"Proc.of MHS'99, IEEE. 51-58 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Makano M,Katoh T et al.: "logistic regression analysis of inherented polymorphism as modulation of stomach cancer"Biomedical soft computing and human science. 4(1). 33-41 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H Nakano M: "Thermal noise and stochastic dynamics of nanosystem"The 3rd Towa unv. International conference on statistical physics. 37 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 松浦弘幸,中野正博: "熱ノイズ駆動型の分子機械、確率共鳴型筋肉モデル"SUT BULLETIN. 8. 40-47 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 松浦弘幸: "100万分の1ミリという極微の世界の技術のもたらすもの"Newton. 20(1). 49 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H,Nakano N Liu LG.: "A sliding model of actin myosin system based on Nyquist theorem"Proc of IEEE-EMBS(Asia-Pacific conference). 377-378 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Wang A,Matsuura H Nakano M: "A dynamic model for muscles motion"Proc.of IEEE-EMBS(Asia-Pacific conference). 379-380 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H Nakano M: "Thermal noise and stochastic dynamics of nanosystem"Statistical Physics (American Institute of Physics). 519. 557-559 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H Nakano M: "dynamics of nano machine and stochastic resonance"Information. 3(2). 203-230 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H Nakano M: "relativistic schwinger Dyson Formalism"GRIPS Research Report Series. 2000-2. 1-2 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H and Nakano M: "Actin Myosin Systems Based on the Stochastic Resonance"Biomedical Soft computing and Human Science, Biomedical Fuzzy Systems Association. 4(1). 23-31 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Nakano M, Katoh T, et, al: "Logistic Regression Analysis of Inherited Polymorphism as Modulators of Stomach Cancer"Biomedical Soft Computing and Human Science. 4(1). 33-41 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Stochastic Dynamics of Molecular Machine, It's nanomachine which is based on Nyquist Theory"Proceeding of the 1999 International Symposium on Micromechatronics and Human science (MHS'99), IEEE. ISBN 0-7803-5790-6. 51-58 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Thermal Noise and stochastic Dynamics of Nanosystem ; n An Application for Actin Myosin System"The 3 rd Tohwa univ. International Conference on Statistical Physics. 37. (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M, ey al: "Mechanical Fatigue on Histocompatible Polymeric Materials"7 th SPSJ International Polymer Conference, The Society of Polymer Science, Japan. 145. (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Stochastic dynamics of Molecular Machine"Japanese Association for Mathematical Biology, JAMB Nesletter. 29. 10 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M, Liu LG: "A Sliding Model of Actin-Myosin System Based on Nyquist Theorm, proc.of IEEE-EMBS Asia- Pacific Conference on Biomedical Engineering"part 1/2 ISBN7-5062-4828-x, World Publishing Corporation International Academic Publish. 376-378 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Wang A BQ, Matsuura H, Nakano M, Liu LG: "A Dynamic Model for Muscle's Motion, proc.of IEEE-EMBS Asia-Pacific Conference on Biomedical Engineering"part 1/2 ISBN7-5062-4828-x, World Publishing Corporation International Academic Publish. 379-380 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Thermal Noise and Stochastic Dynamics of Nanosystem, Statistical Physics"AIP Conference Proc. 519 (ISBN1-56369-940-8, ISSN0094-243x), American Institute of Physics. 557-559 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Heavy Atoms based on Schwinger-Dyson Formalism"The 8^<th> Asia Pacific Physics Conference, Academia Sinica. 160. (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Masahiro N, Matsuura H: "relativistic Calculation on Pion Condensation"Book of Abs, International Chemical Congress of Pacific Basin Societies, phy. 10(654). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Masahiro N: "Field Theory of heavy atoms"Book of Abs, International Chemical Congress of Pacific Basin Societies, phy. 10(654). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Dynamics of Nanomachine and Stochastic Resonance"Information. 3(2). 203-230 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Relativistic Schwinger-Dyson Formalism"GRIPS Research Report Series. 2000-002. 1-2 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Dynamics of Nanomachine and Stochastic Resonance"GRIPS Research Report Series. 2000-002. 3-15 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Masahiro N: "Forecasting method on the quantum physics and Econophysics"GRIPS Research Report Series. 2000-002. 37-44 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "Population Dynamics and Econophysics based on Social Biology and Modern Physics"GRIPS Research Report Series. 2000-002. 45-49 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H, Nakano M: "A Bio-Molecular Machine and Actuator from the Mesoscopic Standpoint"JAMS Newsletter, Japanese Society of Mathematical Biology. 32. 22 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Matsuura H,Nakano M,Liu LG.: "A Sliding Model of Acten Myosin System based on Nyquist Theorem"Proc.of IEEE_EMBS Asia-Pacific Conference on Biomedical Engineering. ISBN7-5062-4828-X. 377-378 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Matsuura H,Nakano M: "Dynamics of Nanomachine and Stochastic Resonance"Information. 3(2). 203-230 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Matsuura H,Nakano M: "Thermal Noise and Stochastic Dynamics of Nanosystem"AIP Conference Proc.. 519. 557-559 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 中野正博: "Nuclear Schwinger-Dyson Methodの新展開"素粒子研究. 102(1). 68-72 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 松浦弘幸,中野正博,藤正巖,井街宏: "確率力学で動作するナノマシンシステムの原理"日本機械学会年次大会論文集. 00-1. 713-714 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Matsuura H,Nakano M,: "Bio-molecular machine and actuator from the mesoscopic standpoint"JAMS Newsletter. 32. 22 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 中野正博(分担): "インターネットを利用した医療問診・診断支援システムファジィとソフトコンピューティングハンドハンドブック"共立出版. 927-929 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Matsuura H.,Nakano M.: "Stochastic Dynamics of molecular machine nanomachine which is based on Nyquist Theory"Proc. of 1999 International Symp. on Micromechatronics and Human Science (MHS'99, IEEE). 0-7803-5790-6. 51-58 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Matsuura H.,Nakano M.: "Thermal noise and stochastic dynamics of nano system"The 3rd Tohwa Univ. International Conference on Statistical Physics. 37 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Matsuura H.,Nakano M.: "Stochastic dynamics of molecular machine"JAMB Newsletter. 29. 10 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 松浦弘幸,井街宏,藤正巌: "確率共鳴型筋肉モデルノ機械特性"第37回日本生物物理学会年会. 39. S148 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 松浦弘幸,藤正巌,井街宏: "筋肉組織を模倣した確率共鳴型ナノマシン"Design & System Conference '99 (日本機械学会). 99-27. 382-385 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 中野正博,松浦弘幸: "相対論的場の理論を用いた超重原子の記述"1999計算化学討論会(日本化学プログラム交換機構). 90-91 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 松浦弘幸: "100万分の1ミリという極微の世界の技術のもたらすもの"Newton. 20(1). 49 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 松浦弘幸,中野正博: "熱ノイズ駆動型の分子機械・確率共鳴型筋肉モデル"SUT BULLETIN. 8. 40-47 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 松浦弘幸・中野正博: "ナノマシンとしてのアクチン・ミオシン系" 第37回日本ME学会大会論文集. 36. 498 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] HIROYUKI Matsuura,MASAHIRO Nakano: "Actin Myosin systems Based on the stochastic Resonamce" Biomedical Soft Computing and Human suence. 4(1). 23-31 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 松浦弘幸・中野正博(他): "ナノマシンとしてのアクチン・ミオシン系(2)" JAMB News letters. 20. 5 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] HIROYUKI Matsuura,MasaHIRO Nakano: "Movement of Actin Myosin System lnduced by Random noise" Mathematical Topics in Biology. (発表予定). (1999)

    • Related Report
      1998 Annual Research Report
  • [Publications] 松浦弘幸・中野正博: "熱ノイズ駆動のアクチンミオシンモデル" 生物物理(suppl.2). 38. S129 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 内田豪,松浦弘幸: "車軸藻節間細胞内微小顆粒のアクチンフィラメント束上での滑り運動特性" 日本物理学会講演概要集. 53(2). 856-857 (1998)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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