| Project/Area Number |
10660103
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bioproduction chemistry/Bioorganic chemistry
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| Research Institution | University of Tsukuba |
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Principal Investigator |
NOMOTO Shinya University of Tsukuba ・ Department of Chemistry, Associate Professor, 化学系, 講師 (30133028)
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| Project Period (FY) |
1998 – 1999
|
| Project Status |
Completed (Fiscal Year 1999)
|
| Budget Amount *help |
¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 1999: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1998: ¥2,800,000 (Direct Cost: ¥2,800,000)
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| Keywords | A hydrogen flame / Radical reaction / Hydroxyl radical / Hydrogen atom / Reduction / Amino acid |
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| Research Abstract |
Reduction reactions of organic compounds caused by under-flame reaction were performed as follows.
(1) Unsaturated amines were subjected to under-flame reaction using a hydrogen-oxygen flame to give their dimers.
(2) Hydrogenation with desulfurization of sulfur-containing amino acids, such as methionine and S-methylcysteine, was carried out by a hydrogen-oxygen flame to produce aminobutyric acid and alanine, respectively.
(3) Hydrocarboxylation of carbon-carbon double bonds in unsaturated amines and amino acids effected by a hydrogen-oxygen flame proved to show high regioselectivity and yield.
(4) Under-flame reaction using formic acid and ammonia as substrates provided a new formation reaction of glycine.
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