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Epidemiological and Immunological Investigation of the Environmental Allergen Exposure related to Pollinosis Outbreak

Research Project

Project/Area Number 10670340
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionTOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

Principal Investigator

TERANISHI Hidetoyo  Faculty of Medicine Public Health, TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY Associate Professor, 医学部, 助教授 (40115184)

Co-Investigator(Kenkyū-buntansha) KATOH Terutaka  Faculty of Medicine Public Health, TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY Assistant, 医学部, 助手 (80115162)
Project Period (FY) 1998 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥3,700,000 (Direct Cost: ¥3,700,000)
Fiscal Year 1999: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1998: ¥3,400,000 (Direct Cost: ¥3,400,000)
KeywordsPollinosis / Japanese cedar / Allergen / Environment / Airborne pollen / Family study / Epidemiology / ヒノキ / 環境要因 / 免疫学
Research Abstract

The purpose of this study is to clarify the significance of allergen exposure in relation to the recent pollinosis outbreak. The results obtained were as follows :
1. By an epidemiological study on the school children and their families, it was proven that prevalence of the pollinosis in the generation of parents and in the generation of children was significantly higher than that of the generation of grandparents. This study suggests that the generations of parents and children were exposed to the environmental factor that did not exist for the generation of grandparents.
2. Though it was shown that the Japanese cedar pollen is the most important allergen in many regions, important roles of Gramineae pollen and pear pollen were also recognized in several regions. In Japanese cedar pollen exposure, both weather condition and the physiology fluctuation of the cedar were demonstrated to be important factors by atmospheric pollen survey.
3. On the major allergen of Japanese cedar pollen, methodological investigation was performed. Cry j 1 in the pollen grain was evaluated quantitatively by an ELISA method. The method revealed to be a useful method for evaluation of the environmental allergen standard, which is acceptable for pollinosis patients.

Report

(3 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • Research Products

    (25 results)

All Other

All Publications (25 results)

  • [Publications] 寺西秀豊、加藤輝隆、加須屋實、他: "富山県の学童とその家族のスギ花粉症発症率の地域的特徴"花粉症研究会会報. 11. 30-35 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Teranishi H., Kenda Y., Katoh T., Kasuya M., et al.: "Possible role of climate change in the pollen scatter of Japanese cedar Cryptomeria japonica in Japan"Climate Research. 14. 65-70 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Yanagisawa S., Hayasaka S., Teranishi H., et al.: "Seasonal allergic conjunctivitis induced by Japanese pear pollen"Jpn. J. Ophthalmol.. 43. 240-242 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 斎藤真巳、寺西秀豊: "マイクロプレートリーダーを用いた簡便なスギ花粉アレルゲン―Cryj1―の定量法の確立"日本林学会誌. 81. 318-324 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Taira H., Teranishi H., and Kenda Y.: "The formation of pollen in male flowers and yearly atmospheric pollen counts of Cryptomeria japonica in the following year"Allergology International. 47(4). 297-302 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 寺西秀豊、劔田幸子、加須屋實、他: "花粉症と情報システム―環境情報の予防医学的活用―"富山医科薬科大学医学会誌. 11(1). 12-15 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Teranishi H., Kenda Y., Yoshida M., and Kasuya M: "Advances in the Prevention of Occupational Respiratory Diseases, by Chiyotani K.(Ed.)"Elsevier. 6 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Teranishi H., et al.: "Regional Features of Sugi Pollinosis Among School Children and the Family in Toyama Prefecture."Pollen Allergy and Prevention. 11. 30-35 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Teranishi H., et al.: "Possible role of climate change in the pollen scatter of Japanese cedar Cryptomeria japonica in Japan."Climate Research. 14. 65-70 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Yanagisawa S., et al.: "Seasonal allergic conjunctivitis induced by Japanese pear pollen."Jpn. J. Ophthalmol.. 43. 240-242 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Saito M., et al.: "Development of the simple quantitative method for Cry j 1 in sugi pollen using microplate reader."J. Jpn. For. Soc.. 81. 318-324 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Taira H., et al.: "The formation of pollen in male flowers and yearly atmospheric pollen counts of Cryptomeria japonica in the following year."Allergology International. 47(4). 297-302 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Teranishi H.: "Pollinosis and pollen forecast : Preventive medicine using an information System."Toyama Medical J.. 11(1). 12-15 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Teranishi H., et al.: "Advances in the Prevention of Occupational Respiratory Diseases, by Chiyotani K. (Ed.)"Elsevier. 6 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 寺西秀豊,加藤輝隆,加須屋實,他: "富山県の学童とその家族のスギ花粉症発症率の地域的特徴."花粉症研究会会報,. 11. 30-35 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] Teranishi H., Kenda Y., Katoh T., Kasuya M., et al.: "Possidle role of climate change in the pollen scatter of Japanese cedar Cryptomeria japonica in Japan."Climate Research. 14. 65-70 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] Yanagisawa S., Hayasaka S., Teranishi H., et al.: "Seasonal allergic conjunctivities induced by Japanese pear pollen."Jpn. J. Ophthalmol.. 43. 240-242 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 齋藤真巳,寺西秀豊,: "マイクロプレートリーダーを用いた簡便なスギ花粉アレルゲンーCry j 1ーの定量法の確立."日本林学会誌. 81. 318-324 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Taira H., Teranishi H., and Kenda Y.: "The formation of pollen in male flowers and yearly atmospheric pollen counts of Cryptomeria japonica in the following year."Allergology International. 47(4). 297-302 (1998)

    • Related Report
      1999 Annual Research Report
  • [Publications] 寺西秀豊 劒田幸子,加須屋實,他: "花粉症と情報システムー環境情報の予防医学的活用ー."富山医科薬科大学医学会誌. 11(1). 12-15 (1998)

    • Related Report
      1999 Annual Research Report
  • [Publications] Teranishi H., Kenda Y., Yoshida M., and Kasuya M.: "Advances in the Prevention of Occupational Respiratory Diseases, by Chiyotani K.(Ed.)"Elsevier. 6P (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Taira H.,Teranishi H.,and Kenda Y: "The formation of pollen in male flowers and yearly atmospheric pollen counts of Cryptomeria japonica in the following year." Allergology International,. 47(4). 297-302 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 土田 豊,寺西秀豊,加須屋 實,他: "富山県におけるスギ花粉症発症日調査-発症日を予報して初期投与を-" 医報とやま. 1224. 8-15 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Natzir R.,Teranishi H.,Kitgawa M.and Kasuya M.: "A novel venom rotein of the Asian bee(Apis cerana indica) with an affinity to human alpha 1-microglobulin.." Allergology International. in press.

    • Related Report
      1998 Annual Research Report
  • [Publications] Teranishi H.,Kenda Y.,et al.: "Chiyotani K.(Ed.) Advances in the Prevention of Occupational Respiratory Diseases-Elsevier Amsterdam" Occupational pollen allergy due to artificial pollination among Japanese farmers., 6 (1998)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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