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Mechanism of toxin synthesis using cultured poisonous mushroom

Research Project

Project/Area Number 10670380
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Legal medicine
Research InstitutionAkita University

Principal Investigator

GONMORI Kunio  Akita University School of Medicine Research Assoc., 医学部, 助手 (10006744)

Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2000: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1999: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1998: ¥2,800,000 (Direct Cost: ¥2,800,000)
KeywordsMushroom poisoning / Cultivation / Magic mushroom / Growth factor / Analysis / HPLC / 毒きのこ / 幻覚きのこ / 毒成分
Research Abstract

Several kind of mushrooms has strong toxicity to kill people. However, there have been only few reports of toxicological analysis on poisonous mushroom in forensic field. This study aimed to cultivate some poisonous mushrooms for the purpose of investigation and research in forensic toxicology. In our experiment the following mushrooms were cultivated, Pleurotus ostreatus, Lentinus edodes, Psilocybe cubensis, Amanita virosa, Lampteromyces japonicus and Gymnopilus spectabilis. Eventually the cultivation of Lyophyllum and Psilocybe cubensis resulted well-grown mushrooms. In the case of the Psilocybe cubensis, psilocybin and psilocin are the main hallucinogenic components. We observed the effect of storage on the concentration of these two hallucinogens. From harvesting the Psilocybe cubensis the freezing method provided the most valuable results to store mushrooms. A sample from a poisonous case suggested magic mushroom ingestion was analyzed. The mushroom was described as Psilocybe subcubensis. Recently the interest of the magic mushroom poisoning appears to be growing around the world. This research attempts to promote the investigation protocol for magic mushroom's cases.

Report

(4 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (3 results)

All Other

All Publications (3 results)

  • [Publications] 権守邦夫,吉岡尚文: "当教室で経験したきのこ中毒検査事例"秋田県救命救急研究会誌. 5. 74-78 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] KUNIO GONMORI, NAOFUMI YOSHIOKA: "Poisoning Cases by Mushroom"Journal of Akia Emergency Medicine. 5. 74-78 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 権守邦夫,吉岡尚文: "当教室で経験したきのこ中毒検査事例"秋田県救命救急研究会誌. 5. 74-78 (2001)

    • Related Report
      2000 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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