• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Antigen Analysis of Latex Allergy

Research Project

Project/Area Number 10670813
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Dermatology
Research InstitutionFujita Health University

Principal Investigator

MATSUNAGA Kayoko  Fujita Health University, School of Medicine, Assistant Pfofessor, 医学部, 講師 (80131192)

Project Period (FY) 1998 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥2,800,000 (Direct Cost: ¥2,800,000)
Fiscal Year 1999: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1998: ¥2,300,000 (Direct Cost: ¥2,300,000)
KeywordsLatex allergy / Contact urticaria / Skin prick test / Antigen analysis / ILZSA / Immunoblot / Specific lgE antibody / Inhibition immunoblot / ELISA / インエビッションイムノブロット / 食物アレルギー
Research Abstract

1) We performed alaSTAT AlaBLOT Specific lg E Assay using sera of 33 cases with latex allergy. We found several bands between 14.7kD and 113kD. The extract of a commercial latex glove inhibited most of these bands.
2) Immunoblot assay against the commercial latex glove using the same sera showed several bands. The extract inhibited one band below 7.2kD, and 28, 37 and 49 kDs bands. It inhibited 23kD band of non-ammoniated latex immunoblot using the same sera.
3) The extract of the commercial latex glove and non-ammoniated latex had common bands, one below 7.2kD, and three bands at 15, 30, and 51kD.
These results showed that our cases had two or three major latex allergens. They are Hev b 6.03 or Hev 8 of 14.7kD, and a band of 30kD which is related to latex fruit syndrome. Two band against the latex glove extract were inhibited by the latex glove extract itself. One was below 7.2kD and the other was 37kD. We suppose that they are Hev b 6.02(hevein, 47.kD) and Hev b 3(βー13-glucanese, 37kD). Inhibition immunoassay against latex glove or related fruits using havein, the related fruits or vegetables will show the mechanism of cross-reactivity between latex and related plants.

Report

(3 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • Research Products

    (24 results)

All Other

All Publications (24 results)

  • [Publications] 秋田浩孝,他: "ラテックスアレルギー患者2例-手術時における予防対策-"皮膚. 41. 319-323 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 冨高晶子,他: "ラテックスアレルギー30例の重症度と特異IgE抗体,皮膚テストの関連性"日本皮膚アレルギー学会雑誌. 7. 28-35 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 冨高晶子,他: "Oral Allergy Syndromeに伴う蕁麻疹-栗による症例-"アレルギーの臨床. 20. 37-40 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 冨高晶子,他: "栗摂取によるアナフィラキシー"アレルギー. 49(4月号). (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 冨高晶子,他: "ラテックスアレルギーの臨床"アレルギーの臨床. 19. 22-26 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 冨高晶子,他: "ラテックスアレルギーと食物"アレルギー科. 9. 41-45 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 秋田浩孝,他: "職業性ラテックスアレルギー30例のまとめ(5月号決定)"アレルギー. (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Akita H, et al.: "Actual conditions of Latex allergy in high risk nurses in a Japanese general hospital"Environmental Dermatology. Vol.(1). 26-34 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Akita H, et al.: "Experience of operation for two cases with latex allergy"Skin Research. Vol. 41(3). 319-323 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Tomitaka A,et al: "Relevance of Latex Specific lgE and Skin test (skin prick test or use test) to severity of clinical synptons in thirty cases with latex allergy"Jpn.J.Dermatoallergol. 7(2). 28-35 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Tomitaka A, et al: "Clinical aspect of latex allergy"The Allergy in Practice. 19(9). 754-758 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Tomitaka A, et al: "Clinical aspect of hypersensitivity to latex and chestnut"The Allergy in Practice. 20(1). 37-40 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Tomitaka A, et al: "Cross reactivity between latex and foods"Allergology. 9(1). 41-45 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Tomitaka A, et al: "Anaphylaxis to Chestnut"Jap J.Allergol. (in press). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Akita H, et al: "30 cases with occupational latex allergy"Jap J Allergol. (in press. (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 秋田浩考他: "ラテックスアレルギー患者2例-手術時における予防対策-"皮膚. 41. 319-323 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 冨高晶子他: "ラテックスアレルギー30例の重症度と特異IgE抗体、皮膚テストの関連性"日本皮膚アレルギー学会雑誌. 7. 28-35 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 冨高晶子他: "Oral Allergy Syndrome に伴う蕁麻疹-栗による症例-"アレルギーの臨床. 20. 37-40 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 冨高晶子他: "栗摂取によるアナフィラキシー"アレルギー. 49. 4月号決定 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 冨高晶子他: "ラテックスアレルギーの臨床"アレルギーの臨床. 19. 22-26 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 冨高晶子他: "ラテックスアレルギーと食物"アレルギー科. 9. 41-45 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 秋田浩孝他: "アレルギー"職性ラテックスアレルギー30例のまとめ. 5月号決定 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 冨高晶子 他: "栗によるアナフィラキシー症状を発症したラテックスアレルギーの4例" 日本ラテックスアレルギー研究会会誌. 2. 30-37 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] Akita H: "Actual conditions of latex allergy in high risk nurses in a Japanese general hospital" Environmental Dermatology. 6 未定. (1999)

    • Related Report
      1998 Annual Research Report

URL: 

Published: 1998-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi