| Project/Area Number |
10671336
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | HOKKAIDO UNIVERSITY |
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Principal Investigator |
YAMANAKA Masanori Hokkaido Univ., Colleg of Med.Tech., Lec., 医療技術短期大学部, 講師 (40166757)
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| Co-Investigator(Kenkyū-buntansha) |
WADA Tatuhiko Hokkaido Univ., Colleg of Med.Tech., Prof., 医療技術短期大学部, 教授 (90002112)
YASUDA Kazunori Hokkaido Univ., Grad.School of Med., Prof., 大学院・医学研究科, 教授 (20166507)
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| Project Period (FY) |
1998 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 2000: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 1999: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1998: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Keywords | Anterior cruciate ligament reconstruction / biomechanical properties / Cyclic load / cyclic displacement / 静的破断試験 / ハイブリッド代用材料 |
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| Research Abstract |
This study was conducted to clarify the influence of cyclic displacement on the structural properties of four types of femur-graft-tibia complexes used to reconstruct the anterior cruciate ligament. Fifty hind limbs from pigs were used. In two groups, bone-patellar tendon-bone grafts were secured with interference screws (groups A) or the suture-post technique (group B). In three groups, multistrand flexor tendons were fixed using the tape-staple technique (group C), the sutures-tied-over-a-button technique (group D) or the interference screw techniqe (group E) In each group, five femur-graft-tibia complexes underwent tensile failure tests without cyclic displacement. The other five complexes underwent 5000 cycles of cyclic elongation for 2 mm, and, then, underwent the tensile failure tests. The initial stiffness significantly decreased after cyclic displacement in each group, although there were no significant differences in the linear stiffness and the ultimate failure load between the tests with and without cyclic displacement. These findings suggest that 5000 cycles of repetitive elongation of the femur-graft-tibia complex by 2 mm does not jeopardize the graft fixed with the procedures used in this study, despite of a slight but significant increase of an anterior-posterior laxity of the knee.
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