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PATHOLOGY OF PEDIATRIC LUMBAR ENDPLATE LESION, BIOMECHANICAL, BIOCHEMICAL, AND MOLECULAR BIOLOGICAL EVALUATION.

Research Project

Project/Area Number 10671363
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionThe University of Tokushima

Principal Investigator

KATOH Shinsuke  DEPARTMENT OF ORTHOPEDIC SURGERY, SCHOOL OF MEDICINE, THE UNIVERSITY OF TOKUSHIMA, ASSOCIATE PROFESSOR, 医学部, 助教授 (30243687)

Co-Investigator(Kenkyū-buntansha) SAIRYO Koichi  DEPARTMENT OF ORTHOPEDIC SURGERY, SCHOOL OF MEDICINE, THE UNIVERSITY OF TOKUSHIMA, LECTURER, 医学部, 講師 (10304528)
YASUOKA Susumu  DEPARTMENT OF NURSING, SCHOOL OF MEDICAL SCIENCE, THE UNIVERSITY OF TOKUSHIMA, PROFESSOR, 医療技術短期大学部, 教授 (30035414)
IKATA Takaaki  DEPARTMENT OF ORTHOPEDIC SURGERY, SCHOOL OF MEDICINE, THE UNIVERSITY OF TOKUSHIMA, PROFESSOR, 医学部, 教授 (80108860)
HAMADA Yoshitaka  DEPARTMENT OF ORTHOPEDIC SURGERY, SCHOOL OF MEDICINE, THE UNIVERSITY OF TOKUSHIMA, CLINICAL FELLOW, 医学部・附属病院, 医員
Project Period (FY) 1998 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1999: ¥500,000 (Direct Cost: ¥500,000)
KeywordsADOLESCENTS / LUMBAR SPINE / ENDPLATE / SPONDYLOLYSIS / SPONDYLOLISTHESIS / BIOMECHANICS
Research Abstract

The failure in lumbar kinematics caused by pars defects is considered to be important factor for the subsequent spinal disorders such as bony deformity and slippage. Clinically, we investigated the kinematics of pediatric lumbar spine with or without pars defects with special reference to the instantaneous axis of rotation (IAR) during lumbar flexion to extension motion. The results suggested that movements of the vertebrae with early stage pars defects may be close to that of normal vertebrae ; whereas, in the progressive and terminal stages of spondylolysis, IAR deviated compared to the normal spine, indicating the failure in lumbar kinematics as the stage of the pars defects advanced. Biomechanically, we evaluated load-displacement behavior under anterior shear loading in the spine with or without pars defects, and found that under such loading in the spine without the pars defects the posterior elements, which showed high rigidity and strength, mostly supported the loading. While in the spine with pars defects, anterior element, which showed comparatively less rigidity and strength, directiy supported the loading. From those clinical and biomechanical viewpoints, we concluded that the failure in the lumbar kinematics occurred in the lumbar spine with pars defects.

Report

(3 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • Research Products

    (26 results)

All Other

All Publications (26 results)

  • [Publications] 西良浩一 ほか: "前方剪断負荷における幼若脊椎の負荷変位動態:分離椎と非分離椎との比較"日本脊椎外科学会雑誌. 11巻(印刷中). (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 酒巻忠範 ほか: "発育期腰椎の屈曲・伸展回転中心:分離椎および非分離椎の比較"日本脊椎外科学会雑誌. 11巻(印刷中). (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 西良浩一 ほか: "発育期腰椎分離症のすべり進展メカニズム臨床的および実験的検討より"臨床スポーツ医学. 16巻. 1093-1096 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 梶浦清司 ほか: "発育期腰椎分離症のすべり発生増強と骨成熟との関連性について:臨床的、生体力学的検討"日本整形外科スポーツ医学会誌. 19巻. 73 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 西良浩一 ほか: "発育期腰椎分離症のすべり発生増強に及ぼす骨年令の影響:臨床的検討"日本脊椎外科学会雑誌. 10巻. 115 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 梶浦清司 ほか: "発育期腰椎分離症のすべり発生増強に及ぼす骨年令の影響:生体力学的検討"日本脊椎外科学会雑誌. 10巻. 269 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 浜田佳孝 ほか: "スポーツと腰痛"からだの科学. 206巻. 57-64 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 西良浩一 ほか: "幼若脊椎における終板の生体力学的強度"日本整形外科学会雑誌. 73巻. 1678 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 西良浩一 ほか: "発育期腰椎分離症のすべり進展メカニズムの生体力学的検討"臨床整形外科. 33巻. 581-584 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 加地伸介 ほか: "発育期腰椎分離すべり症と腰椎横突起との関連性について"中部日本整形外科災害外科学会雑誌. 41巻. 751-752 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] K.Sairyo et al.: "The pathomechanism of isthmic lumbar spondylolisthesis.A biomechanical study in immature calf spines"Spine. 23巻. 1442-1446 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Sairyo K, Ikata T. Katoh S, Sakamaki T, Yonekura D, Murakami R: "Load-displacement behavior of lumbar spinal functional unit under anterior shear loading."J Jpn Spine Research Society. 11: (in press). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Sakamaki T, Ikata T, Katoh S, Sairyo K, Hamada Y, Yoshida N: "Axis of rotation from extended to flexed positionin juvenile lumbar spine with or without spondylolysis."J Jpn Spine Research Society. 11: (in press). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Sairyo K, Ikata T, Katoh S, Fujii K, Mishiro T: "The pathomechanism of slippage in immature lumbar spine with pars defect. A clinical and biomechanical study."Jpn J Clinical Sports Medicine. 16. 1093-1096 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Sairyo K, Ikata T, Katoh S, Fujii K, Kaji , S: "Progression and development of slippage of spondylolysis in children and adolescents with reference to bony age."J Jpn Spine Research Society. 10. 115 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Kajiura K, Ikata T, Katoh S, Sairyo K, Saito Y, Murakami R: "Influence of vertebral bony age for the progression and development of slippage of spondylolysis in children and adolescent : a biomechanical study."J Jpn Spine Research Society. 10. 269 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Sairyo K, Ikata T, Katoh S, Kajiura K, Terai T, Murakami R: "Biomechanical strength of lumbar endplate in immature spine."Jpn J Orthop Assoc.. 73. S1678 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 西良浩一 ほか: "発育期腰椎分離症のすべり進展メカニズム:臨床的および実験的検討より"臨床スポーツ医学. 16巻. 1093-1096 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 梶浦清司 ほか: "発育期腰椎分離症のすべり発生増強と骨成熟との関連性について:臨床的、生体力学的検討"日本整形外科スポーツ医学会誌. 19巻. 73 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 西良浩一 ほか: "発育期腰椎分離症のすべり発生増強に及ぼす骨年令の臨床的検討"日本脊椎外科学会雑誌. 10巻. 115 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 梶浦清司 ほか: "発育期腰椎分離症のすべり発生増強に及ぼす骨年令の生体力学的検討"日本脊椎外科学会雑誌. 10巻. 269 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 浜田佳孝 ほか: "スポーツと腰痛"からだの科学. 206巻. 57-64 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 西良浩一 ほか: "幼若脊椎における終板の生体力学的強度"日本整形外科学会雑誌. 73巻. 1678 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] K.Sairyo et al.: "The pathomechanism of isthmic lumbar spondylolisthesis.A biomechanical study in immature calf spines." SPINE. 23. 1442-1446 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 西良浩一ほか: "発育期脊椎分離症のすべり発生、増強に及ぼす骨年齢の影響、臨床的検討" 日本脊椎外科学会誌. 10(印刷中). (1999)

    • Related Report
      1998 Annual Research Report
  • [Publications] 梶浦清司ほか: "発育期脊椎分離症のすいべり発生、増強に及ぼす骨年齢の影響、生体力学的検討" 日本脊椎外科学会誌. 10(印刷中). (1999)

    • Related Report
      1998 Annual Research Report

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Published: 1999-04-01   Modified: 2018-02-02  

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