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Investigation on anatomical factors inhibiting the posterior shift of the thoracic spinal cord and the development of reliable methods of posterior decompression of the spinal cord for the thoracic OPLL-myelopathy

Research Project

Project/Area Number 10671378
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionSaitama Medical School

Principal Investigator

TSUZUKI Nobuyuki  Saitama Medical School, Medical Department, Professor, 医学部, 教授 (10049794)

Co-Investigator(Kenkyū-buntansha) SAIKI Kunio  Saitama Medical School, Medical Department, Lecturer, 医学部, 講師 (40215520)
ABE Ryoji  Kasnetsu Hospital, Department of Orthopaedic Surgery, Head of Department, 整形外科, 部長 (30193014)
Project Period (FY) 1998 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥2,700,000 (Direct Cost: ¥2,700,000)
Fiscal Year 1999: ¥1,300,000 (Direct Cost: ¥1,300,000)
Fiscal Year 1998: ¥1,400,000 (Direct Cost: ¥1,400,000)
Keywordsthoracic spine / ossification of the posterior longitudinal ligament / thoracic myelopathy / posterior approach
Research Abstract

As a method of safe and reliable decompression of the spinal cord for thoracic-OPLL myelopathy, the posterior approach was selected and its disadvantage, I.e., the insufficient degree of decompression caused by thoracic kyphosis, was improved by elimination of three major anatomical factors which inhibited the posterior shift of the thoracic spinal cord. They were: (1) longitudinal factor, I.e., anterior pulling effects of spinal cord segments, above and below OPLL, (2) longitudotransverse factor, I.e., holding-down effect of the parts of dura; mid-dorsal part and lateral part which extended into nerve-sheath, (3) transverse factor, I.e., anterior tethering effect of thoracic roots and denticular ligaments. Means of elimination of these factors were: (1) extensive cervicothoracic laminoplastic decompression, (2) longitudinal durotomy, (3) facetectomy and root-OPLL release. OPLL resection or anterior transfer was finally performed if necessary. These procedures were performed through staged posterior approaches in fifteen cases of thoracic OPLL-myelopathy. A mean age was 56 years (range: 42-68 years) and a mean follow-up was 42 months (range: 5-100 months). Neurology improved in all cases, with little postoperative complications. Radiological pictures proved the effectiveness of elimination of posterior-shift-inhibiting factors for the spinal cord decompression.

Report

(3 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] 都築暢之ほか: "胸髄後方移動阻害因子-胸推後縦靱帯骨化巣における研究-"日本脊椎外科学会雑誌. 9・1. 123 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 都築暢之ほか: "胸椎後縦靱帯骨化症に対する広範囲頚胸部脊柱管拡大術(都築法)"関節外科. 17・12. 1517-1523 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 都築暢之ほか: "胸椎後縦靱帯骨化症における脊髄安全性の向上の試み-必要な手段と進入法-"日本整形外科学会雑誌. 73・2. S389 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 都築暢之ほか: "胸椎後縦靱帯骨化症に対する段階的後方進入脊髄除圧法"日本脊椎外科学会雑誌. 11・1. 15 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] N Tsuzuki et al.: "How to secure the safety of spinal cord during thoracic OPLL-decompression: required steps and approaches."Journal of Japanese Orthopaedic Association. 73(2). S389 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] N Tsuzuki et al.: "Mechanism of inhibition of posterior shift of the thoracic spinal cord; Investigation in thoracic OPLL."Journal of Japan Spine Research Society. 9(1). 123 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] N Tsuzuki et al: "Extensive cervicothoracic laminoplastic decompression for the thoracic myelopathy caused by OPLL (Tsuzuki method)."Journal of Joint Surgery. 17(12). 1517-1523 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] N Tsuzuki et al.: "Staged posterior decompression of the spinal cord for thoracic OPLL-myelopathy."Journal of Japan Spine Research Society. 11(1). 15 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 都築暢之ほか: "胸髄後方移動阻害因子-胸椎後縦靭帯骨化症における研究-"日本脊椎外科学会雑誌. 9・1. 123 (1998)

    • Related Report
      1999 Annual Research Report
  • [Publications] 都築暢之ほか: "胸椎後縦靭帯骨化症に対する広範囲頚胸部脊柱管拡大術(都築法)"関節外科. 17・12. 1517-1523 (1998)

    • Related Report
      1999 Annual Research Report
  • [Publications] 都築暢之ほか: "胸椎後縦靭帯骨化症における脊髄安全性向上の試み-必要な手段と進入法-"日本整形外科学会雑誌. 73・2. S389 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 都築暢之ほか: "胸椎後縦靭帯骨化症に対する段階的後方進入脊髄除圧法"日本脊椎外科学会雑誌. 11・1. 15 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 都築暢之 ほか: "胸髄後方移動阻害機序-胸椎後縦靱帯骨化症における研究-" 日本脊椎外科学会雑誌. 9. 123 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 都築暢之 ほか: "胸椎後縦靱帯骨化症に対する広範囲頚胸部脊柱管拡大術(都築法)" 関節外科. 17・12. 1517-1523 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 都築暢之 ほか: "胸椎後縦靱帯骨化症除圧における脊髄安全性向上の試み-必要な手段と進入法-" 日本整形外科学会雑誌. 73・2. S389 (1999)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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