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Investigation of Intraoperative monitoring for motor function

Research Project

Project/Area Number 10671439
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Anesthesiology/Resuscitation studies
Research InstitutionNara Medical University

Principal Investigator

INOUE Satoki  Dept.Anesthesiology, Nara Medical University, Research Associate, 麻酔科学教室, 助手 (50295789)

Co-Investigator(Kenkyū-buntansha) KAWAGUCHI Masahiko  Dept.Anesthesiology, Nara Medical University, Assistant Professor, 医学部, 講師 (60275328)
FURUYA Hitoshi  Dept.Anesthesiology, Nara Medical University, Professor, 医学部, 教授 (70183598)
Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥2,600,000 (Direct Cost: ¥2,600,000)
Fiscal Year 2000: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1999: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 1998: ¥1,600,000 (Direct Cost: ¥1,600,000)
KeywordsAnesthesia / MEP / Spinal sargery / intraoperative monitoring / Oatic sargery / 麻醉 / モニタリング / 運動機能 / 経頭蓋刺激
Research Abstract

Monitoring of motor-evoked potentials(MEPs) is employed to examine functional integrity of descending motor pathway during thoracic aortic surgery and spinal surgery. We have improved methods of intraoperative MEP setup and evaluated the clinical relevance.
Throughout the study we could detect intraoperative changes in MEPs during during surgical procedures in some cases and get some clue to decide operative procedures. We reviewed and published our experiences of intraoperative motor evoked potentials(MEPs) monitoring for more than 100 operations on the spine or spinal cord. We think that we could show in the article that Intraoperative monitoring of MEPs might be a reliable indicator of spinal cord motor function. And now, we are preparing for submitting manuscripts of MEP variability and MEP from anal sphincter as an index for bowel and rectal function.
We are going to continue investigating remained problems about intraoperative MEP after discontinuance of financial support from Grnd-in-Ald for Sientific Research.

Report

(4 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (18 results)

All Other

All Publications (18 results)

  • [Publications] Sakamoto T. Kawaguchi M Inoue S. Furuya H: "Suppressive effect of nitrous oxide on motor ercked potential can be reversed by rain stimulation in rabbits under ketamine/fentanyl anaesthesia, but not with propofol"Br J Anaesth. 86. 395-402 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Kawaguchi M, Sakamoto T Inoue S, Kakimoto M.Furuya H et al: "Low dose propofol as a supplement to ketamine-based anesthesia during Patiacpewtive monitoring moter evolked potentials. "Spine. 25. 974-979 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 瓦口至孝、垣本めい子、井上聡己 他: "全身麻酔中の運動誘発モニタリング術中に電位低下を示した.骨盤骨折の2症例"麻酔. 49. 514-5* (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 垣本めい子、井上聡己、坂本尚典ら: "術中運動誘発電位モニタリング115症例のレビュー"麻酔. 49. 240-244 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] 下田孝司、井上聡己、垣本めい子: "大動脈手術中の運動誘発神経モニタリングで異常の見られた2症例"麻酔. 49. 1247-1249 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sakamoto T, Kawaguchi M.Inoue S, Furuya H: "Suppressive effect of nitrous oxide on motor evoked potentials can be reversed by train stimulation in valiants under ketomine/forcer/anesthesia, but not with additional propull"Br.J Anaesih. 86. 395-402 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Kawaguch M, Sakamoto T, Inoue S, Kakimoto M, Furuya H: "Low dose propotal as a supplement to kecamine-based anesthesia during intraoperative monitoring of motor-evoked potentials."Spine. 25. 974-9 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Kawaguchi Y.Kakimoto M, Inoue S, Sakamoto T, Furuya H, et al.: "Monitoring of motor evoked potentials during insertion of thosacral screws for reconstruction of pelvic fracture in two patients."Masui. 49. 514-8 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Kakimoto M, Inoue S, Sakamoto T, Kawaguch M, Furuya H et al.: "Intraoperative motor evoked potential monitoring arenew of of 115 cases."Masui. 49. 240-4 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Simoda T, Inoue S, Kakimoto M, Sakamoto T, Furuya H et al.: "Two cases of isohemic changes indicated in the amplitude of motor evoked potentials during thoracoabdomine aortic aneurysm hepaw."Masui. 49. 1247-9 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Sakamoto T.Kawagada M Inove S.Furuya.H: "Suppressive effect of nitrous oxide on motor evoked potentials can be reversed by train stimulation in rabbits under ketamine/fentanyl anaesthesia, but not with perfect"Br J Anaesth. 86. 395-402 (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kawajuchi M,Sakamoto T.Inove S.Kalamoto M.Faraga H et al.: "Low dose propofol as a supplement to ketamine based anesthesia during intraoperative monitoring of motor evoked potentials"Spine. 25. 974-9 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 瓦口至孝,垣本めい子,井上聡己 他: "全身麻酔中の運動誘発モニタリング術中に電位低下を示した骨盤骨折の2症例"麻酔. 49. 514-518 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 垣本めい子,井上聡己,坂本尚典 ら: "術中運動誘発電位モニタリング115症例のレビュー."麻酔. 49. 240-244 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 下田孝司,井上聡己,垣本めい子: "大動脈手術中の運動誘発神経モニタリングで異常の見られた二症例"麻酔. 49. 1247-1249 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 瓦口至孝、垣本めい子,井上聡己 他: "全身麻酔下での運動誘発電位モニタリング-術中に電位低下を示した骨盤骨切の2症例-"麻酔. (in press).

    • Related Report
      1999 Annual Research Report
  • [Publications] 垣本めいこ,井上聡己、坂本尚典 他: "術中運動誘発電位モニタリング:115症例のレビュー"麻酔. (in press).

    • Related Report
      1999 Annual Research Report
  • [Publications] Masahiko Kawaguchi: "The Effect of Sevoflurane on Myogenic Motor-Evoked Potentials Induced by Single and Paired Transcranial Electrical Stimulation of the Motor Corter During Nitrous-Oxide Ketamine/Fertanyl Anesthesia" Journal of Neurosurgical Aneshesiology. 10. 131-136 (1998)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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