| Project/Area Number |
10671726
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Kanagawa Dental College |
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Principal Investigator |
TAKAHASHI Kazuto Dentistry, Kanagawa Dental College Prof., 歯学部, 教授 (00084707)
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| Co-Investigator(Kenkyū-buntansha) |
TERADA Hitoshi Dentistry, Kanagawa Dental College Assistant, 歯学部, 助手 (70267508)
MATSUO Masato Dentistry, Kanagawa Dental College Assistant Prof., 歯学部, 講師 (30190416)
KISHI Yoshiaki Dentistry, Kanagawa Dental College Associate Prof., 歯学部, 助教授 (60084779)
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| Project Period (FY) |
1998 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥3,000,000 (Direct Cost: ¥3,000,000)
Fiscal Year 2000: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1999: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 1998: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | vessels of pulp / pulpitis / resin cast / SEM / TEM / lynphatic vessels / 歯髄の微小循環 / リンパ管様静脈 / 血管鋳型法 / 走査型電子顕微鏡 / 静脈 / 微小血管鋳型 / リンパ管 |
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| Research Abstract |
The purpose of this study was to examine the characteristics of microcirculation beneatn the exposed surface in the dental pulp of young mongrel dogs. Upper and lower maxillary teeth of dogs were experimentally exposed by an air-turbin with cooling water and kept open without any sealing. Examination methods were divided into the following two ways : scanning electron microscopic examination in vascular corrosion casts and transmission electron microscopic examination in ultrathin sections.
Results : 1) Four hours after exposure, methyl methacrylate resin leaked out from capillries ; the resin leaked diffused beneath the exposed surface out of order. 2) One day after exposure, a globular formed resin changed into beads-like appearance of vascular casts in some parts beneath the exposed surface. 3) Seven days, a globular formed casts changed into beads-like appearance of vascular casts in some parts beneath the exposed surface. 4) Lymphatic vesseles-like lumen which was composed of endothelium layer, but lacking in basal membrane pericytes were recognized. In conclusion, it is conceivable that capillary lumen seen through ultrathin section corresponds with beads-like appearance of vascular casts. Venules having beads-like appearance located in the surrounding area of the abscess were considered to have lymphatic characteristics from a view point of its disposition and structure. Therefore, it may be a part of venular fluid absorbing systems which regulates diffusion and/or transport of exudate substances from outside of the blood vessels.
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