| Project/Area Number |
10671735
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional basic dentistry
|
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| Research Institution | Tokyo Medical and Dental University |
|---|
Principal Investigator |
TODA Kazuo Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 講師 (80134708)
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|---|
| Project Period (FY) |
1998 – 1999
|
| Project Status |
Completed (Fiscal Year 1999)
|
| Budget Amount *help |
¥3,300,000 (Direct Cost: ¥3,300,000)
Fiscal Year 1999: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1998: ¥2,200,000 (Direct Cost: ¥2,200,000)
|
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| Keywords | nociceptor / polymodal / mechanoreceptor / gingiva / tooth pulp / periodontium / bitter / rat / スラジキニン / 苦味 / フオンフライ |
|---|
| Research Abstract |
Properties of nociceptors of skin have been extensively investigated, however, less is known about the characteristics of nociceptive afferents that innervate mucosal areas. In the present review, recent studies of the nociceptors in the oral mucosa are summarized. Oral mucosal nociceptors has different properties from the skin nociceptors. This means quite important for detection of nociceptive stimulus which applied during daily food intake. In addition, some of the mucosal nociceptors were also excited by bitter solution, suggesting that these nociceptors in the oral mucosa play a significant role in production of taste sensation by irritant foods. Tooth pulpal and periodontal nociceptors were also investigated, showing that distributions of nociceptors are different among these structures.
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