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EPIDEMIOLOGICAL STUDY ON DENTAL STATUS AND TEMPOROMANDIBULAR JOINT IN SUBJECTS WITH RHEUMATOID ARTHRITIS

Research Project

Project/Area Number 10671944
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 矯正・小児・社会系歯学
Research InstitutionKYUSHU DENTAL COLLEGE

Principal Investigator

TAKEHARA Tadamichi  KYUSHU DENTAL COLLEGE, DEPARTMENT OF PREVENTIVE DENTISTRY, PROFESSOR, 歯学部, 教授 (00038879)

Project Period (FY) 1998 – 2000
Project Status Completed (Fiscal Year 2000)
Budget Amount *help
¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 2000: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1999: ¥700,000 (Direct Cost: ¥700,000)
Fiscal Year 1998: ¥1,000,000 (Direct Cost: ¥1,000,000)
KeywordsRHEUMATOID ARTHRITIS / TEMPOROMANDIBULAR DISORDERS / DENTAL STATUS / 有病者 / 高齢者
Research Abstract

In order to understand the dental and temporomandibular joint (TMJ) in subjects with rheumatoid arthritis, 142 female patients were compared with 143 control subjects of the same age. The number of remaining teeth and edentulous rate were significantly lower in the RA group than non-RA group. Meanwhile, the number of DMF teeth, as well as frequency of complete denture and removable partial dentures were significantly higher in the RA group. In RA, the incidence of subjective symptoms was 1.4% for pain in the TMJ, 4.9% for pain on mouth opening, and 14.8% for difficulty with mouth opening. Further, signs of TMJ tenderness were found in 9.2%, clicking in 12.7%, and crepitus in 35.9% of those patients. A significantly greater number of subjects who demonstrated crepitus were found in the RA group than the non-RA group. As for temporomandibular disorders (TMD), the incidence was 67.6% in the RA group and 32.9% in the non-RA group. The occurrence of degenerative joint disorders was most frequent among patients with TMD, which was found to correlate with Steinbrocker's stage and RA disease duration.

Report

(4 results)
  • 2000 Annual Research Report   Final Research Report Summary
  • 1999 Annual Research Report
  • 1998 Annual Research Report
  • Research Products

    (25 results)

All Other

All Publications (25 results)

  • [Publications] Akifusa,S.,Ohguchi,M et al: "Increase in Bcl-2 level promoted by CD40 ligation correlates with inhibition of B cell opoptosis induced by vacuolar trpe H+ ATP ase inhibitor"Exp.Cell Res. 238. 82-89 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Ansai,T.,Awano,S. et al.: "Purification and characterization of alkaline phosphataes containing phosphotyrosyl phosphatase activity from the bacterium Prevottella intermedia"FEBS Lett.. 428. 157-160 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Katoh,Y.,Ansai,T. et al: "A comparison of DA1 scores and characteristics of occlusal traits in three ethnic groups of Asian Origin."Int.Dent.J.. 48. 405-411 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Chen,X.,Ansai,T. et al.: "Isolation, cloning, and expression of an acid phosha tase containing phos photyrosyl phosphatase activity from Prevotella intermedia"J Bacteriol. 181. 7107-7114 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Awano,S.,Ansai,T., et al: "Sequencing, expression and biochemical characterization of Porphyromones gingivalis pepO gene encoding a protein homologous to human"FEBS Lett. 460. 139-144 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Ansai,T.,Tahara,A., et al.: "Influence of initial colonization of mutans streptococci on caries hazard in Japanese Preschool children"Rediatr. Dent.. 22. 377-380 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Ansai,T.,and Takehara T: "Recent Research Developments in Microbiology"Research Signpost (印刷中). (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Akifusa, S., Ohguchi, M., Koseki, T., Nara, K., Semba, I., Yamato, K., Okahashi, N., Merino, R., Nunez, G., Hanada, N., Takehara, T.and Nishihara, T.: "Increase in Bcl-2 level promoted by CD40 ligation correlates with inhibition of B cell apoptosis induced by vacuolar type H+-ATPase inhibitor."Exp.Cell Res. 238. 82-89 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Ansai, T., Awano, S., Chen, X., Fuchi, T., Arimoto, T., Akifusa, S.and Takehara, T.: "Purification and characterization of alkaline phosphatase containing phosphotyrosyl phosphatase activity from the bacterium Prevotella intermedia."FEBS Lett.. 428. 157-160 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Katoh, Y., Ansai, T., Takehara, T., Yamashita, Y., Miyazaki, H., Jenny, J.and Cons, N.: "A comparison of DAI scores and characteristics of occlusal traits in three ethnic groups of Asian origin."Int.Dent.J.. 48. 405-411 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Chen, X., Ansai, T., Awano, S., Iida, T., Barik, S.and Takehara, T.: "Isolation, cloning, and expression of an acid phosphatase containing phosphotyrosyl phosphatase activity from Prevotella intermedia."J.Bacteriol.. 181. 7107-7114 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Awano, S., Ansai, T., Mochizuki, H., Yu, W., Tanzawa, K., Turner, AJ.and Takehara, T.: "Sequencing, expression and biochemical characterization of the Porphyromonas gingivalis pepO gene encoding a protein homologous to human endothelin-converting enzyme."FEBS Lett.. 460. 139-144 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Ansai, T., Tahara, A., Ikeda, M., Katoh, Y., Miyazaki, H., and Takehara, T.: "Influence of initial colonization of mutans streptococci on caries hazard in Japanese preschool children."Pediatr.Dent.. 22. 377-380 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2000 Final Research Report Summary
  • [Publications] Ansai T.,Tahara A, et al: "Influence of initial colonization of mutans streptococci on caries hazard in Japanese preschool chilren."Pediato.Dent. 22. 377-380 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Chen X.,Ausai T. et al.: "Isolation, Cloning and expression of an acid phosphatase containg phosphotyrosyl phosphatase activity from Prevottella intermedia."J.Bacteriol. 181. 7107-7114 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Awano S.,Ausai T. et al: "Sequencing, expression and biochemical characterization of the Porphyromonas gingivals pepO gene encoding a protein homolgous"FEBS Lett. 460. 139-144 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Ausai T.Awano S. et al.: "Purification and characterzation of alkaline phosphatase containg phosphotyrosyl phosphatase activity from the bacterium Provotellainermedia"FEBS Lett. 428. 157-160 (1998)

    • Related Report
      2000 Annual Research Report
  • [Publications] Ausai T.,Akifusa S., et al.: "Ideutification of cell division genes, ftsQ and ftsA from prophyromonous gingivalis."J Dent Res. 77. 929 (1998)

    • Related Report
      2000 Annual Research Report
  • [Publications] Murata T,Ausai T. et al.: "Extracts of Prevotella intermedia and Active bacillus actinomycetemcomitaus inhibit alkaline phosphatase activity in osteoblast"Oral Diseases. 3. 106-112 (1997)

    • Related Report
      2000 Annual Research Report
  • [Publications] 安細敏弘,秋房住郎 他: "口腔分子生物学小事典"口腔保健協会.

    • Related Report
      2000 Annual Research Report
  • [Publications] 竹原直道ら: "顎関節症-診査・診断・治療のガイドライン"九州歯科大学同窓会学術振興会平成7年度指定研究研究成果報告書. (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 鱒見進一ら: "顎関節症患者のための問題志向型治療録の試作および検討"九州歯科学会雑誌. 53. 295-317 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 山川摩利子ら: "慢性関節リウマチ患者の口腔と顎関節の健康状態に関する疫学的研究"発表予定.

    • Related Report
      1999 Annual Research Report
  • [Publications] 鱒見進一ほか: "顎関節症患者のための問題志向型診療録の試作および検討" 九州歯科学会誌. 53(2)印刷中. (1999)

    • Related Report
      1998 Annual Research Report
  • [Publications] 竹原直道: "九州歯科大学附属病院における顎関節症患者の動向" 「顎関節症-診査・診断・治療のガイドライン」. 報告書 印刷中. (1999)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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