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Sport scientific approach on the healthy society for ageing - Relation between the immune response and exercise for health -

Research Project

Project/Area Number 10680065
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 体育学
Research InstitutionOsaka University of Health and Sport Sciences

Principal Investigator

MASUHARA Mitsuhiko  Osaka University of Health and Sport Sciences, Health and Sport Sciences, Professor, 体育学部, 教授 (40067236)

Co-Investigator(Kenkyū-buntansha) UMEBAYASHI Kaoru  Osaka University of Health and Sport Sciences, Health and Sport Sciences, Assist Professor, 体育学部, 助教授 (30148473)
TAKISE Sadafumi  Osaka University of Health and Sport Sciences, Health and Sport Sciences, Professor, 体育学部, 教授 (30067251)
MATSUMURA Shinya  Osaka University of Health and Sport Sciences, Health and Sport Sciences, Professor, 体育学部, 教授 (20067242)
KAMI Katsuya  Osaka University of Health and Sport Sciences, Health and Sport Sciences, Assist Professor, 体育学部, 助教授 (20204612)
Project Period (FY) 1998 – 1999
Project Status Completed (Fiscal Year 1999)
Budget Amount *help
¥3,100,000 (Direct Cost: ¥3,100,000)
Fiscal Year 1999: ¥1,400,000 (Direct Cost: ¥1,400,000)
Fiscal Year 1998: ¥1,700,000 (Direct Cost: ¥1,700,000)
Keywordsimmune response / ageing / PWC85%HRmax / physical fitness / 細胞性免疫 / 筋収縮 / 全身持久能力 / リンパ球幼若化反応 / インターロイキン / 運動 / 高齢者 / リンパ球 / PHA / CD4 / CD8 / NK
Research Abstract

This study was performed to determined the relationship between the immune response and exercise for health on ageing . The subjects were 10 healthy male of 59 〜 81 years old. They had physical fitness test, measurement of blood components and analysis of lymphocyte subsets.
The summary of the results were as follows.
1. The grip strength decrease with the ageing(p<0.05), but PWC85%HRmax of scale of endurance ability was independent of ageing. This results suggest that endurance ability is possible to be influenced by the exercise of everyday life.
2. We observed that relation between grip strength and total serum protein, and CD4 of lymphocyte subsets were significant on the ageing (respectively p<0.05, p<0.01).
3. This results suggested that the Cellular immune response depend on the protein of muscle and blood.
4. A high correlation was seen between CD8 of lymphocyte subsets and triglyceride(p<0.05). This result suggest that hyperlipemia increase the suppressor lymphocyte subset.

Report

(3 results)
  • 1999 Annual Research Report   Final Research Report Summary
  • 1998 Annual Research Report
  • Research Products

    (24 results)

All Other

All Publications (24 results)

  • [Publications] 増原光彦: "Effefcts of Physical Exercise on the Lymphocytic Response in Middle Age Men"J. American Society of Hematology. 76. 2130-2130 (1991)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 増原光彦: "骨格筋蛋白に対するブピバカイン注入後の運動効果"体力科学. 36. 791-791 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 増原光彦: "体育専攻女子学生の網状赤血球動態の特性と運動性貧血について"体力科学. 36. 791-791 (1992)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 増原光彦: "スポーツ選手の膝障害と大腿部筋力に関する基礎的研究"日本総合健診医学会誌. 22. 367-375 (1995)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 上勝也: "Changes of vinculin and extracellular matrix components following blunt trauma to rat skeletal muscle"Med. Scie. Sports Exerc.. 25. 832-840 (1993)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 上勝也: "骨格筋再生機構に対するサイトカインとシグナル伝達の役割"運動生化学、 8,48-50(1996). 8. 48-50 (1996)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 増原光彦: "Basic research on the effects of doing exercise on the immune response"British J. of Haematology. 102. 315-315 (1998)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 滝瀬定文: "Effects of Exercise on the Vascular Disease of Hyperlipidemic Rats"Japanese J. Judo Therapy. 7. 425-434 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 増原光彦: "動的膝伸展運動における運動強度と大腿直筋の酸素動態の関係について"体力科学. 49. 203-221 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 増原光彦: "運動生理学読本"不昧堂出版株式会社. 143 (1997)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Nieman, D.C. et al.: "Effects of long-endurance running on immune system parameters and lymphocyte function in experienced in marathoners"Int.J. Sports Med.. 10. 317-323 (1989)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Smith J.A., Telford R.D., Mason I.B. & Weidmann M.J.: "Exercise, Training and Neutrophil Microbicidal Activity"Int.J.Sports Med.. 11. 179-187 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] D.C.Nieman, D.A.Henson et al: "Effects of brief, heavy exertion on circulating lymphocyte subpopulations and proliferative response"Med.Sci.Sports Exerc.. 24. 1339-1345 (1992)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] A.B.Gray, R.D.Telford, M.Collins and M.J. Weidemann: "The response of leukocyte subsets and plasma hormones to interval exercise"Med.Sci.Sports Exerc.. 25. 1252-1258 (1993)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Pedersen BK, Ullum H.: "NK cell response to physical activity : possible mechanisms of action"Med. Sci. Sports Exerc.. 26. 140-146 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] Nieman DC, Ahle JC, Henson DA et al.: "Indomethacin does not alter the natural killer cell response to 2.5 hours of running"J. Appl. Physiol.. 79. 748-755 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      1999 Final Research Report Summary
  • [Publications] 増原 光彦: "Effefcts of Physical Exercise on the Lymphocytic Response in Middle Age Men" J.American Society of Hematology. 76. 2130 (1991)

    • Related Report
      1998 Annual Research Report
  • [Publications] 増原 光彦: "骨格筋蛋白に対するブピバカイン注入後の運動効果" 体力科学. 36. 791 (1992)

    • Related Report
      1998 Annual Research Report
  • [Publications] 増原 光彦: "体育専攻女子学生の網状赤血球動態の特性と運動性貧血について" 体力科学. 36. 791 (1992)

    • Related Report
      1998 Annual Research Report
  • [Publications] 増原 光彦: "Basic research on the effects of doing exercise on the immune response" British J.of Haematology. 102(1). 315 (1998)

    • Related Report
      1998 Annual Research Report
  • [Publications] 上 勝也: "Changes of vinculin and extracellular matrix componentsfollowing blunt trauma to rat skeletal muscle" Med.Scie.Sports Exerc.25(7). 832-840 (1993)

    • Related Report
      1998 Annual Research Report
  • [Publications] 上 勝也: "骨格筋再生機構に対するサイトカインとシグナル伝達の役割" 運動生化学. 8. 48-50 (1996)

    • Related Report
      1998 Annual Research Report
  • [Publications] 増原 光彦: "運動生理学読本" 不昧堂出版kk, 141 (1997)

    • Related Report
      1998 Annual Research Report
  • [Publications] 増原 光彦: "The Nagano Symposium on Sports Sciences" Cooper Publishing Group,carmel,IN,USA, 646(6) (1998)

    • Related Report
      1998 Annual Research Report

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Published: 1998-04-01   Modified: 2016-04-21  

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