| Project/Area Number |
10680802
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Kitasato University |
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Principal Investigator |
HIROSE Minoru. Dept. of Clinical Engineering, Kitasato University of Allied Health Sciences, Lecturer, 医療衛生学部, 講師 (50286382)
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Satoshi Dept. of Clinical Engineering, Kitasato University of Allied Health Sciences, Professor, 医療衛生学部, 教授 (40050463)
KOBAYASHI Hirosuke Dept. of Clinical Engineering, Kitasato University of Allied Health Sciences, Lecturer, 医学部, 講師 (70153632)
古垣 達也 北里大学, 医療衛生学部, 助手 (60306644)
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| Project Period (FY) |
1998 – 1999
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| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥1,200,000 (Direct Cost: ¥1,200,000)
Fiscal Year 1999: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1998: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Inhaled nitric oxide / nitric oxide (NO) / Chronic respiratory failure / Home oxygen therapy / Delivery device / Pulmonary hypertension / 酸素セーバー |
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| Research Abstract |
We developed two kinds of delivery devices, a breathing interval dependence type and a gas supply time setup type, for inhaled nitric oxide (INO) in the long-term use, for the purpose of the prevention of the cor pulmonale in the chronic respiratory failure patient. The trial experimental devices improve oxygen saver of the existing being used for home oxygen therapy. The performance test of the device (breathing interval dependence type) was tested by breathing simulation. As the result, the change of NO concentration versus tidal volume was close to the theory value. But the change of NO concentration versus breathing rate made a difference with the increase in the breathing rate. There was a little consumption of the NO gas in this device, it was easy, it can be used for the safety, the occurrence of NOィイD22ィエD2 is very low. We think about that the trial experimental devices turn to practical use. The result of this research was announced in the Japanese medical instrumentation meeting and Japanese medical electronics and biological engineering meeting.
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