Hox genes of the direct-type developing sea urchin Peronella japonica
| Project/Area Number |
10836009
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
自然史科学
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| Research Institution | Kanazawa University |
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Principal Investigator |
YAMAGUCHI Masaki Kanazawa University Fac, Science, Dept. Biology, Associate Prof., 理学部, 助教授 (60182458)
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| Project Period (FY) |
1998 – 1999
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| Project Status |
Completed (Fiscal Year 1999)
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| Budget Amount *help |
¥3,400,000 (Direct Cost: ¥3,400,000)
Fiscal Year 1999: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1998: ¥2,300,000 (Direct Cost: ¥2,300,000)
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| Keywords | Hox gene / echinoderm / direct-type developer / sea urchin / Peronella japonica / Evx-type gene / 直接発生型ワニ / HOX遺伝子 / 進化 / Para HOX遺伝子 / 五放射相称 / 前後軸 |
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| Research Abstract |
Peronella japonica is a direct-type developing sea urchin that metamorphoses in 3 days without feeding, providing us a good system to analyze developmental mechanisms especially at later larval stages to metamorphosis. We surveyed the Hox-type sequences of P. japonica by PCR and RT-PCR, and isolated 13 Hox-type sequences. All of them were detected by RT-PCR, indicative of their expressions in larvae. Phylogenetic analysis and database searches resulted in identification of all the P. japonica orthologs of the Hox genes that have been reported in other sea urchins, plus 3 Hox-type genes: the Evx-type, Xlox-type, and an additional posterior Hox gene. The present results revealed a putative Hox gene cluster of P. japonica, which contains genes representing all the paralog (cognate) groups of vertebrate Hox clusters except that there is a single gene of Hox4-5 types. In spite of the pentaradial body plans lacking apparent cepharic structures, P. japonica appears to retain the Hox cluster that is essentially similar to those of the chordates with bilateral body plans.
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Report
(3 results)
Research Products
(3 results)
