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General Promotion of Cancer Research in Japan

Research Project

Project/Area Number 11177101
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionUniversity of Tokyo

Principal Investigator

TSURUO Tahashi  University of Tokyo, Institute of Molecular and Cellular Biosciences, Professor, 分子細胞生物学研究所, 教授 (00012667)

Co-Investigator(Kenkyū-buntansha) SASAZUKI Takehiko  International Medical Center of Japan, President, 総長(研究職) (50014121)
TAKAI Yoshimi  Osaka University, Graduate School/Faculty of Medicine, Professor, 大学院医学系研究科, 教授 (60093514)
NAKAMURA Yusuke  University of Tokyo, Institute of Medical Science, Professor, 医科学研究所, 教授 (70217909)
TAJIMA Kazuo  Aichi Cancer Center Research Institute, Division of Epidemiology and Prevention, Chief, 研究所, 部長(研究職) (30150212)
TANIGUCHI Tadatsugu  University of Tokyo, Graduate School of Medicine, Professor, 大学院医学系研究科, 教授 (50133616)
Project Period (FY) 1999 – 2005
Project Status Completed (Fiscal Year 2005)
Budget Amount *help
¥3,739,300,000 (Direct Cost: ¥3,739,300,000)
Fiscal Year 2005: ¥2,500,000 (Direct Cost: ¥2,500,000)
Fiscal Year 2004: ¥756,300,000 (Direct Cost: ¥756,300,000)
Fiscal Year 2003: ¥756,300,000 (Direct Cost: ¥756,300,000)
Fiscal Year 2002: ¥756,300,000 (Direct Cost: ¥756,300,000)
Fiscal Year 2001: ¥727,100,000 (Direct Cost: ¥727,100,000)
Fiscal Year 2000: ¥739,000,000 (Direct Cost: ¥739,000,000)
Fiscal Year 1999: ¥1,800,000 (Direct Cost: ¥1,800,000)
KeywordsCancer / Research Materials / Screening / International Scientific Exchange / Support for Young Investigators / Cancer Genome / Gene Manipulated Animals / Molecular Target Therapy / 癌 / 医療・福祉 / 研究資材 / 若手支授
Research Abstract

"Grant-in-Aid for Scientific Research on Priority Areas" has successfully completed the proposed researches.
The research started in 1999 and terminated in 2005. The organization of "General Promotion of Cancer Research in Japan" played the key role in promotion and organization of cancer research in Japan, in co-ordination with other five priority areas in cancer research in Japan. These five areas are: "Mechanisms of oncogenesis and anti-oncogenesis" chaired by Takehiko Sasazuki, "Cancer cell biology" chaired by Yoshimi Takai, "Diagnosis and treatment of cancer" chaired by Yusuke Nakamura, "Epidemiological studies on environmental and host-specific factors for human cancer" chaired by Kazuo Tajima and "Advanced research on cancer" chaired by Tadatsugu Taniguchi.
During the research term, we had general assemblies twice a year with other five priority areas in cancer research. In conjunction with them, we had scientific symposia to exchange our up-front knowledge in cancer research. We … More also had the joint symposium with other priority areas, namely, genome research and brain research.
We had the board meeting four times per year to arrange and promote the cancer researches in six priority cancer research areas.
Regarding international relationship, we had annual meeting with French, German, Chinese and Korean cancer scientists in bilateral basis to exchange our top-front scientific knowledge. Furthermore, we dispatched young scientists to these countries, as well as to the U.S.A. for the scientific information exchange. In July 1&2, 2004, we had international symposium "Global Trends in Cancer Research" in Tokyo.
Seven foreign scientists (from U.S.A., United Kingdom, Germany and New Zealand) and nine Japanese scientists presented their up-dated research results and we could exchange very productive information on cancer research.
In the last year (2005), we published four series books, namely, "molecular carcinogenesis","cancer cell biology","cancer diagnosis and treatment" and "cancer epidemiology", in which our up-front research accomplishments have been described. We hope these books stimulate the interests for cancer research, especially for young researchers and students. Less

Report

(8 results)
  • 2005 Annual Research Report   Final Research Report Summary
  • 2004 Annual Research Report
  • 2003 Annual Research Report
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (1,051 results)

All 2005 2004 2003 2002 2001 2000 Other

All Journal Article (1021 results) Publications (30 results)

  • [Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.2005

    • Author(s)
      Seimiya, H., et al.
    • Journal Title

      Cancer Cell 7

      Pages: 25-37

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Annual Research Report 2005 Final Research Report Summary 2004 Annual Research Report
  • [Journal Article] A full genome scan for gastric cancer.2005

    • Author(s)
      Aoki M
    • Journal Title

      J. Med. Genet 42

      Pages: 83-87

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005

    • Author(s)
      Takaoka A., et al.
    • Journal Title

      Nature published on line

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Long-term effects of radiation dose on inflammatory markers in atomic bomb survivors.2005

    • Author(s)
      Hayashi, T., et al.
    • Journal Title

      Am. J. Med 118

      Pages: 83-86

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-fixation of VEGFR1 ligand-binding domain is important for vasculogenesis/angiogenesis in mice.2005

    • Author(s)
      Hiratsuka, S., et al.
    • Journal Title

      Mol. Cell. Biol 25

      Pages: 346-354

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain.2005

    • Author(s)
      Koshikawa, N., et al.
    • Journal Title

      J Biol Chem. 280

      Pages: 88-93

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Oct-3/4 and Sox2 regulate Oct3/4 gene in ES cells.2005

    • Author(s)
      Okumura-Nakanishi, S., et al.
    • Journal Title

      J. Biol. Chem 280

      Pages: 5307-5317

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis.2005

    • Author(s)
      Oceguera-Yanez, F., et al.
    • Journal Title

      J. Cell Biol 168

      Pages: 221-232

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma.2005

    • Author(s)
      Nitori, N., et al.
    • Journal Title

      Clin. Cancer Res. 11

      Pages: 2531-2539

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Transient strong reduction of PTEN expression by specific RNAi induces loss of adhesion of the cells.2005

    • Author(s)
      Mise-Omata, S., et al.
    • Journal Title

      Biochem. Biophys. Res. Commun 328

      Pages: 1034-1042

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.2005

    • Author(s)
      Nakatsu, N., et al.
    • Journal Title

      Mol Cancer Ther 4

      Pages: 399-412

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Suppression of tumor cell invasiveness by hydrolysable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase-2/-9 activity.2005

    • Author(s)
      Tanimura., et al.
    • Journal Title

      Biochem Biophys Res Commun 330

      Pages: 1306-1313

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HER2 Overexpression increases sensitivity to gefitinib an EGF receptor tyrosine kinase inhibitor through inhibition of HER2/ HER3 heterodimer formation in lung cancer cells.2005

    • Author(s)
      Hirata, A., et al.
    • Journal Title

      Cancer Res 65

      Pages: 4253-4260

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib.2005

    • Author(s)
      Ueno, Y., et al.
    • Journal Title

      Br. J.Cancer 92

      Pages: 1690-1695

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53-defective tumors with a functional apoptosome-mediated pathway : a new therapeutic target.2005

    • Author(s)
      Mashima, T., et al.
    • Journal Title

      J Natl Cancer Inst. 97

      Pages: 765-777

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of ATF3, Caveolin-1 DLC-1 and NM23-H2 as putative antitumorigenic progesterone-regulated genes for ovarian cancer cells by gene profiling.2005

    • Author(s)
      Syed, V., et al.
    • Journal Title

      Oncogene 24

      Pages: 1774-1787

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Estrogen-mediated Post-transcriptional Down-regulation of Breast Cancer Resistance Protein/ABCG2.2005

    • Author(s)
      Imai, Y., et al.
    • Journal Title

      Cancer Res 65

      Pages: 596-604

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Practical range of effective dose for Cre recombinase-expressing recombinant adenoviris without cell toxicity in mammalian cells.2005

    • Author(s)
      Baba, Y., et al.
    • Journal Title

      Microbiol Immunol 49

      Pages: 559-570

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The RAS effector RASSF2 is a novel tumor suppressor gene in human colorectal cancer.2005

    • Author(s)
      Akino, K., et al.
    • Journal Title

      Gastroenterology 129

      Pages: 156-169

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Achlorhydria by ezrin knockdown : defects in the formation/expansion of apical canaliculi in gastric parietal cells.2005

    • Author(s)
      Tamura, A., et al.
    • Journal Title

      J Cell Biol 169

      Pages: 21-28

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas.2005

    • Author(s)
      Nakagawa, T., et al.
    • Journal Title

      J. Urol 173

      Pages: 243-246

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis.2005

    • Author(s)
      Nakagawa, T., et al.
    • Journal Title

      J. Urol 173

      Pages: 1767-1771

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.2005

    • Author(s)
      Izumi, H., et al.
    • Journal Title

      Hum Molec Genet 14

      Pages: 997-1007

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.2005

    • Author(s)
      Takada, H., et al.
    • Journal Title

      Cancer Sci 96

      Pages: 100-110

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Th1-biased humoral immune responses against Wilms tumor gene WT1 product in the patients with hematopoietic malignancies.2005

    • Author(s)
      Wu, F., et al.
    • Journal Title

      Leukemia 19

      Pages: 268-274

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas.2005

    • Author(s)
      Furukawa, T., et al.
    • Journal Title

      Mod. Pathol 18

      Pages: 1034-1042

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] RNA interference targeting aurora kinase A suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.2005

    • Author(s)
      Hata, T., et al.
    • Journal Title

      Cancer Res 65

      Pages: 2899-2905

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The level of angiogenesis and expression of angiogenesis- related genes is prognositic for organ-specific metastasis of renal cell carcinoma.2005

    • Author(s)
      Fukata S., et al.
    • Journal Title

      Cancer 103

      Pages: 931-942

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] JNK phosphorylation of 2014 3 3 regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage2005

    • Author(s)
      Yoshida, K., et al.
    • Journal Title

      Nat Cell Biol 7

      Pages: 278-285

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] dbQSNP : a database of SNPs in human promoter regions with allele frequency information determined by single-strand conformation polymorphism-based method.2005

    • Author(s)
      Tahira, T., et al.
    • Journal Title

      Human Mutation 26

      Pages: 69-77

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes.2005

    • Author(s)
      Qin, M., et al.
    • Journal Title

      Human Mutation 26

      Pages: 104-112

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT.2005

    • Author(s)
      Horiuchi, T., et al.
    • Journal Title

      Genes Immun 6

      Pages: 162-166

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Individual variation of somatic gene mutability in relation to cancer susceptibility : Prospective study on erythrocyte glycophorin A gene mutations of atomic bomb survivors.2005

    • Author(s)
      Kyoizumi, S., et al.
    • Journal Title

      Cancer Res. 65

      Pages: 5462-5469

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic Mutual Relationship between PTEN and p53 in Gastric Cancer.2005

    • Author(s)
      Oki, E., et al.
    • Journal Title

      Cancer Lett 227

      Pages: 33-38

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.2005

    • Author(s)
      Seimiya, H.
    • Journal Title

      Cancer Cell 7

      Pages: 25-37

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A full genome scan for gastric cancer.2005

    • Author(s)
      Aoki, M.
    • Journal Title

      J.Med.Genet 42

      Pages: 83-87

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005

    • Author(s)
      Takaoka, A.
    • Journal Title

      Nature published on line

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Long-term effects of radiation dose on inflammatory markers in atomic bomb survivors.2005

    • Author(s)
      Hayashi, T.
    • Journal Title

      Am.J.Med 118

      Pages: 83-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-fixation of VEGFR1 ligand-binding domain is important for vasculogenesis/angiogenesis in mice.2005

    • Author(s)
      Hiratsuka, S.
    • Journal Title

      Mol. Cell. Biol 25

      Pages: 346-354

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain.2005

    • Author(s)
      Koshikawa, N.
    • Journal Title

      J Biol Chem. 280

      Pages: 88-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Oct-3/4 and Sox2 regulate Oct3/4 gene in ES cells.2005

    • Author(s)
      Okumura-Nakanishi, S.
    • Journal Title

      J.Biol.Chem 280

      Pages: 5307-5317

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dysadherin expression facilitates cell motility and metastatic potential of human pancreatic cancer cells.2005

    • Author(s)
      Shimamura, T.
    • Journal Title

      Cancer Res 64

      Pages: 6989-6995

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis.2005

    • Author(s)
      Oceguera-Yanez, F.
    • Journal Title

      J. Cell Biol 168

      Pages: 221-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prognostic significance of tissue factor in pancreatic ductal adenocarcinoma.2005

    • Author(s)
      Nitori, N.
    • Journal Title

      Clin.Cancer Res. 11

      Pages: 2531-2539

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Transient strong reduction of PTEN expression by specific RNAi induces loss of adhesion of the cells.2005

    • Author(s)
      Mise-Omata, S.
    • Journal Title

      Biochem.Biophys.Res.Commun 328

      Pages: 1034-1042

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chemosensitivity profile of cancer cell lines and identification of genes determining chemosensitivity by an integrated bioinformatical approach using cDNA arrays.2005

    • Author(s)
      Nakatsu, N.
    • Journal Title

      Mol Cancer Ther 4

      Pages: 399-412

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Suppression of tumor cell invasiveness by hydrolysable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase-2/-9 activity.2005

    • Author(s)
      Tanimura.
    • Journal Title

      Biochem Biophys Res Commun 330

      Pages: 1306-1313

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HER2 Overexpression increases sensitivity to gefitinib an EGF receptor tyrosine kinase inhibitor through inhibition of HER2/ HER3 heterodimer formation in lung cancer cells.2005

    • Author(s)
      Hirata, A.
    • Journal Title

      Cancer Res 65

      Pages: 4253-4260

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib.2005

    • Author(s)
      Ueno, Y.
    • Journal Title

      Br. J. Cancer 92

      Pages: 1690-1695

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53-defective tumors with a functional apoptosome-mediated pathway : a new therapeutic target.2005

    • Author(s)
      Mashima, T.
    • Journal Title

      J Natl Cancer Inst. 97

      Pages: 765-777

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of ATF3, Caveolin-1 DLC-1 and NM23-H2 as putative anti-tumorigenic progesterone-regulated genes for ovarian cancer cells by gene profiling.2005

    • Author(s)
      Syed, V.
    • Journal Title

      Oncogene 24

      Pages: 1774-1787

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Estrogen-mediated Post-transcriptional Down-regulation of Breast Cancer Resistance Protein/ABCG2.2005

    • Author(s)
      Imai, Y.
    • Journal Title

      Cancer Res 65

      Pages: 596-604

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Practical range of effective dose for Cre recombinase-expressing recombinant adenovirus without cell toxicity in mammalian cells.2005

    • Author(s)
      Baba, Y.
    • Journal Title

      Microbiol Immunol 49

      Pages: 559-570

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The RAS effector RASSF2 is a novel tumor suppressor gene in human colorectal cancer.2005

    • Author(s)
      Akino, K.
    • Journal Title

      Gastroenterology 129

      Pages: 156-169

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Achlorhydria by ezrin knockdown : defects in the formation/expansion of apical canaliculi in gastric parietal cells.2005

    • Author(s)
      Tamura, A.
    • Journal Title

      J Cell Biol 169

      Pages: 21-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] DNA hypomethylation on pericentromeric satellite regions significantly correlates with loss of heterozygosity on chromosome 9 in urothelial carcinomas.2005

    • Author(s)
      Nakagawa, T.
    • Journal Title

      J. Urol 173

      Pages: 243-246

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis.2005

    • Author(s)
      Nakagawa, T.
    • Journal Title

      J. Urol 173

      Pages: 1767-1771

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.2005

    • Author(s)
      Izumi, H.
    • Journal Title

      Hum Molec Genet 14

      Pages: 997-1007

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Screening of DNA copy-number aberrations in gastric cancer cell lines by array-based comparative genomic hybridization.2005

    • Author(s)
      Takada, H.
    • Journal Title

      Cancer Sci 96

      Pages: 100-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Th1-biased humoral immune responses against Wilms tumor gene WT1 product in the patients with hematopoietic malignancies.2005

    • Author(s)
      Wu, F.
    • Journal Title

      Leukemia 19

      Pages: 268-274

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas.2005

    • Author(s)
      Furukawa, T.
    • Journal Title

      Mod. Pathol 18

      Pages: 1034-1042

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] RNA interference targeting aurora kinase A suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.2005

    • Author(s)
      Hata, T.
    • Journal Title

      Cancer Res 65

      Pages: 2899-2905

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The level of angiogenesis and expression of angiogenesis-related genes is prognostic for organ-specific metastasis of renal cell carcinoma.2005

    • Author(s)
      Fukata S.
    • Journal Title

      Cancer 103

      Pages: 931-42

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] JNK phosphorylation of 2014.3.3 regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage.2005

    • Author(s)
      Yoshida, K.
    • Journal Title

      Nat Cell Biol 7

      Pages: 278-285

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] dbQSNP : a database of SNPs in human promoter regions with allele frequency information determined by single-strand conformation polymorphism-based method.2005

    • Author(s)
      Tahira, T.
    • Journal Title

      Human Mutation 26

      Pages: 69-77

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes.2005

    • Author(s)
      Qin, M.
    • Journal Title

      Human Mutation 26

      Pages: 104-112

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association of MBL gene polymorphisms with major bacterial infection in patients treated with high-dose chemotherapy and autologous PBSCT.2005

    • Author(s)
      Horiuchi, T.
    • Journal Title

      Genes Immun 6

      Pages: 162-166

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Individual variation of somatic gene mutability in relation to cancer susceptibility : Prospective study on erythrocyte glycophorin A gene mutations of atomic bomb survivors.2005

    • Author(s)
      Kyoizumi, S.
    • Journal Title

      Cancer Res. 65

      Pages: 5462-5469

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Early death of mice cloned from somatic cells.2005

    • Author(s)
      Ogonuki, N.
    • Journal Title

      Nat. Genet. 30

      Pages: 253-254

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic Mutual Relationship between PTEN and p53 in Gastric Cancer.2005

    • Author(s)
      Oki, E.
    • Journal Title

      Cancer Lett 227

      Pages: 33-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p-53-defective tumors with a functional apoptosome-mediated pathway : a new therapeutic target.2005

    • Author(s)
      Mashima, T., et al.
    • Journal Title

      J.Nat'l Cancer Inst. 97

      Pages: 765-777

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Stabilization of intergrin-linked kinase by binding to Hsp90.2005

    • Author(s)
      Aoyagi, Y., et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 331

      Pages: 1061-1068

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Akt/ protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G_2/M transition.2005

    • Author(s)
      Katayama, K., et al.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 5725-5737

    • Related Report
      2005 Annual Research Report
  • [Journal Article] 3-Phosphoinositide-dependent protein kinase-1-mediated 1kB kinase beta (IKKB) phosphorylation activates NF-kB signaling.2005

    • Author(s)
      Tanaka, H., et al.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 40965-40973

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Involvement of mitochondrial aggregation in arsenic trioxide (As2O3)-induced apoptosis in human glioblastoma cells.2005

    • Author(s)
      Haga, N., et al.
    • Journal Title

      Cancer Sci. 96

      Pages: 825-833

    • Related Report
      2005 Annual Research Report
  • [Journal Article] Functional subdomain in the ankyrin domain of tankyrase 1 required for poly (ADP-ribosyl) action of TRF1 and telomere elongation.2004

    • Author(s)
      Seimiya, H
    • Journal Title

      Mol. Cell. Biol 24

      Pages: 1944-1955

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage.2004

    • Author(s)
      Shirasawa S
    • Journal Title

      Proc. Natl. Acad. Sci. USA 101

      Pages: 13921-13926

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/Poliovirus Receptor/CD155 through the Ras-Raf-MEK-ERK signaling.2004

    • Author(s)
      Kakunaga, S
    • Journal Title

      J. Biol. Chem 279

      Pages: 36419-36425

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.2004

    • Author(s)
      Fukuhara, T
    • Journal Title

      J. Cell Biol 166

      Pages: 393-405

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.2004

    • Author(s)
      Hamamoto, R., et al.
    • Journal Title

      Nat Cell Biol 6

      Pages: 731-740

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer : genome-wide gene-expression profiles of prostate Cancers and PINs.2004

    • Author(s)
      Ashida, S., et al.
    • Journal Title

      Cancer Res 64

      Pages: 5963-5972

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Gene-environment interaction between the smoking habit and polymorphisms in the DNA repair genes APE1 Asp 148G1u XRCC1 Arg399Gln in Japanese lung cancer risk.2004

    • Author(s)
      Ito, H., et al.
    • Journal Title

      Carcinogenesis 25

      Pages: 1395-1401

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The CYP19 gene codon 39 Typ/Arg polymorphism increases breast cancer risk in subsets of premenopausal Japanese.2004

    • Author(s)
      Hirose, K., et al.
    • Journal Title

      Cancer Epidemiol Biomarkers & Prev 13

      Pages: 1407-1411

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Negative regulation of IFN-alpha/beta sinaling by IFN regulatory factor 2 for homeostatic development of dendritic cells.2004

    • Author(s)
      Honda K., et al.
    • Journal Title

      Proc Natl Acad Sci USA 101

      Pages: 2416-2421

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.2004

    • Author(s)
      Suzuki, H., et al.
    • Journal Title

      nature Genet 36

      Pages: 417-422

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Oligo-astheno-teratozoospermia in mice lacking Cnot7 a regulator of retinoid X receptor beta.2004

    • Author(s)
      Nakamura, T., et al.
    • Journal Title

      nature Genetics 36

      Pages: 528-533

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap.2004

    • Author(s)
      Yao, R., et al.
    • Journal Title

      Oncogene 23

      Pages: 6023-6030

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of BMP and Activin Membrane-bound Inhibitor (BAMBI) an Inhibitor of Transforming Growth Factor-{beta} Signaling as a Target of the b-Catenin Pathway in Colorectal Tumor Cells.2004

    • Author(s)
      Sekiya T., et al.
    • Journal Title

      J Biol Chem. 279

      Pages: 6840-6846

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Anteriorization of neural fate by ICAT a negative regulator or Wnt signaling.2004

    • Author(s)
      Satoh, K., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 101

      Pages: 8017-8021

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Perspectives on cancer immuno-epidemiology.2004

    • Author(s)
      Nakachi, K., et al.
    • Journal Title

      Cancer Sci 95

      Pages: 921-929

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A Novel Snake Venom Vascular Endothelial Growth Factor (VEGF) Predominantly Induces Vascular Permeability through Preferential Signaling via VEGF Receptor-1.2004

    • Author(s)
      Takahashi, H., et al.
    • Journal Title

      J. Biol. Chem 279

      Pages: 46304-46314

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Constitutive and induced CD44 shedding by ADAM-like proteases and membrane-type 1 matrix metalloproteinase.2004

    • Author(s)
      Nakamura, H., et al.
    • Journal Title

      Cancer Res. 64

      Pages: 876-882

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-superfamily and Runx proteins.2004

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Oncogene 23

      Pages: 4232-4237

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-superfamily signaling.2004

    • Author(s)
      Mochizuki, T., et al.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 31568-31574

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Combination chemotherapy, CADO-CVP with radiotherapy and stem cell support can be beneficial for adolescent and adult estheisonneuroblastoma.2004

    • Author(s)
      Mishima Y., et al.
    • Journal Title

      Cancer 101

      Pages: 1437-1444

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Paclitaxel administered weekly in patients with docetaxel-resistant metastatic breast cancer : A single-center study.2004

    • Author(s)
      Sawaki M., et al.
    • Journal Title

      Tumori 90

      Pages: 11932-11932

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Localization of hRad9, hHusl, hRadl and hRadl7 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body.2004

    • Author(s)
      Nabetani, A., et al.
    • Journal Title

      J. Biol. Chem 279

      Pages: 25849-25857

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dysadherin expression facilitates cell motility and metastatic potential of human pancreatic cancer cells.2004

    • Author(s)
      Shimamura, T., et al.
    • Journal Title

      Cancer Res 64

      Pages: 6989-6995

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Promotion of carcinogenesis and oxidative stress by dietary cholesterol in rat prostate.2004

    • Author(s)
      Homma, Y., et al.
    • Journal Title

      Carcinogenesis 25

      Pages: 1011-1014

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Alternative mechanisms of gene amplification in human cancers.2004

    • Author(s)
      Kuwahara, Y., et al.
    • Journal Title

      Genes Chromosomes & Cancer 41

      Pages: 125-132

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HST-1/FGF-4 plays a critical role in crypt cell survival and facilitates epithelial cell restitution and proliferation.2004

    • Author(s)
      Sasaki, H., et al.
    • Journal Title

      Oncogene 23

      Pages: 3681-3688

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Familial essential thrombocythemia associated with a dominant-posotive activating mutation of the c-MPL gene which encodes for the recepter for thrombopoietin.2004

    • Author(s)
      Ding, J., et al.
    • Journal Title

      Blood 103

      Pages: 4198-4200

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-cell leukemia/lymphoma.2004

    • Author(s)
      Ishida, T., et al.
    • Journal Title

      Clin. Cancer Res 10

      Pages: 7529-7539

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A technique for noninvasive respiratory gated radiation treatment systern based on a real time 3D ultrasound image correlation : a phantom study.2004

    • Author(s)
      Sawada, A., et al.
    • Journal Title

      Med Phys 31

      Pages: 245-250

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Targeting hypoxic cancer cells with a protein prodrug is effective in experimental malignant ascites.2004

    • Author(s)
      Inoue, M., et al.
    • Journal Title

      Int J Oncol 25

      Pages: 713-720

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.2004

    • Author(s)
      Kitajiri, S., et al.
    • Journal Title

      J.Cell Biol 116

      Pages: 559-570

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.2004

    • Author(s)
      Umeda, K., et al.
    • Journal Title

      J.Biol.Chem 279

      Pages: 44785-44794

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Granulocyte-macrophage colony-stimulating factor is a keratinocyte-derived factor involved in regulating the proliferation and differentiation of neonatal mouse epidermal melanocytes in culture.2004

    • Author(s)
      Hirobe T., et al.
    • Journal Title

      Exp Cell Res. 297

      Pages: 593-606

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Neural fold heterogeneity suggests an alternative hypothesis2004

    • Author(s)
      Weston JA., et al.
    • Journal Title

      Dev Dyn. 229

      Pages: 118-130

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cdc42 and mDia3 regulate microtubule attachment to kinetochores.2004

    • Author(s)
      Yasuda, S., et al.
    • Journal Title

      Nature 428

      Pages: 767-771

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Preferential cis-syn thymine dimer bypass by DNA polymerase occurs with biased fidelity.2004

    • Author(s)
      McCulloch SD., et al.
    • Journal Title

      nature 428

      Pages: 97-100

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Implications for fidelity and polymerase switching of translesion synthesis.2004

    • Author(s)
      Kusumoto, R., et al.
    • Journal Title

      Genes Cells 9

      Pages: 1139-1150

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sensitization of tumor-associated endothelial cell apoptosis by the novel vascular-targeting agent ZD6126 in combination with cisplatin.2004

    • Author(s)
      Goto, H., et al.
    • Journal Title

      Clin. Cancer Res 10

      Pages: 7671-7676

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa ZD 1839).2004

    • Author(s)
      Kakiuchi, S., et al.
    • Journal Title

      Hum. Mol. Genet 13

      Pages: 3029-3043

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Myopath phenotype in transgenic mice expressing mutated PABPN1 as a model of oculopharyngeal muscular dystrophy.2004

    • Author(s)
      Hino, H., et al.
    • Journal Title

      Human Mol. Genet. 13

      Pages: 1-10

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Loss of PGC-specific expression of the orphan nuclear receptor ERR- results in reduction? of germ cell number in mouse embryos.2004

    • Author(s)
      Mitsunaga, K., et al.
    • Journal Title

      Mech. Dev. 121

      Pages: 237-246

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Excess concordance of cancer incidence and lifestyles in married couples (Japan) : survival analysis of paired rate data.2004

    • Author(s)
      Izumi, S., et al.
    • Journal Title

      Cancer Causes and Control 15

      Pages: 551-558

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Improving the efficiency of nested case-control studies of interaction by selecting controls using counter matching on exposure.2004

    • Author(s)
      Cologne, JB., et al.
    • Journal Title

      Int. J. Epidemiol 33

      Pages: 485-492

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of transcripts expressed preferentially in hemocytes of Ciona intestinalis that can be used as molecular markers.2004

    • Author(s)
      Wakoh, T., et al.
    • Journal Title

      DNA Res 11

      Pages: 345-352

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Gene expression profiling identifies a set of transcripts that are up-regulated in human testicular seminoma.2004

    • Author(s)
      Yamada, S., et al.
    • Journal Title

      DNA Res 11

      Pages: 335-344

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Immunity against mouse thymus-leukemia antigen (TL) protects against development of lymphomas induced by a chemical carcinogen N-butyl-N-nitrosourea.2004

    • Author(s)
      Tsujimura, K., et al.
    • Journal Title

      Cancer Sci 95

      Pages: 914-919

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Pladienolides new substances from culture of Streptomyces platensis Mer-11107 III In vitro and in vivo antitumor activities.2004

    • Author(s)
      Mizui, Y., et al.
    • Journal Title

      J Antibiot 57

      Pages: 188-196

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors.2004

    • Author(s)
      Fukazawa, H., et al.
    • Journal Title

      Mol Cancer Ther 3

      Pages: 1281-1288

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Interaction between glucose-regulated destruction domain of DNA topoisomerase IIa and MPN domain of Jab1/CSN5.2004

    • Author(s)
      Yun, J., et al.
    • Journal Title

      J Biol Chem 279

      Pages: 31296-31303

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synthesis and structure-activity relationships of thioflavone derivatives as specific inhibitors of the ERK-MAP kinase signaling pathway.2004

    • Author(s)
      Kataoka, T., et al.
    • Journal Title

      Bioorg Med Chem 12

      Pages: 2397-2407

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Novel histone deacetylase inhibitors : cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones.2004

    • Author(s)
      Jose, B., et al.
    • Journal Title

      Bioorg Med Chem. Lett 14

      Pages: 1256221-1256221

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sensitivity to gefitinib (Iressa : ZD 1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinasel/2 and EGF receptor/ Ark pathway for proliferation2004

    • Author(s)
      Ono, M., et al.
    • Journal Title

      Mol. Cancer Ther 3

      Pages: 465-472

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibition of lymphangiogenesis-related properties of murine lymphatic endothelial cells and lymph node metastasis of lung cancer by the matrix metalloproreinase inhibitor MMI270.2004

    • Author(s)
      Nakamura E., et al.
    • Journal Title

      Cancer Sci 95

      Pages: 25-31

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Apollon ubiquitinates SMAC and caspase-9 and has an essential cytoprotection function.2004

    • Author(s)
      Hao, Y., et al.
    • Journal Title

      Nat Cell Biol 6

      Pages: 849-860

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Gefitinib reverses breast cancer resistance protein-mediated drug resistance.2004

    • Author(s)
      Yanase, K., et al.
    • Journal Title

      Mol Cancer Ther 3

      Pages: 1119-1125

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Structure of tyroscherin an antitumor antibiotic against IGF-1-dependent cells from Pseudallescheria sp.2004

    • Author(s)
      Hayakawa, Y., et al.
    • Journal Title

      J. Antibiot 57

      Pages: 634-638

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex.2004

    • Author(s)
      Zhang, H-F., et al.
    • Journal Title

      Cancer Res 64

      Pages: 1114-1121

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] CK2 controls multiple protein kinasesby phosphorylating a kinase-targeting molecular chaperoneCdc37.2004

    • Author(s)
      Miyata, Y., et al.
    • Journal Title

      Mol. Cell. Biol 24

      Pages: 4065-4074

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Telomere-bound TRF1 and TRF2 stall replication fork at telomeric rpeats.2004

    • Author(s)
      Ohki, R., et al.
    • Journal Title

      Nucl. Acids Res 32

      Pages: 1627-1637

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Polycomb groupsuppressor of zeste 12 links heterochromatin protein lalpha and enhancer ofzeste 22 2.2004

    • Author(s)
      Yamamoto K., et al.
    • Journal Title

      J Biol Chem 279

      Pages: 401-406

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] M-Phase kinases inducephospho-dependent ubiquitination of somatic Weel by SCF,β-TrCP.2004

    • Author(s)
      Watanabe, N., et al.
    • Journal Title

      Proc. Natl. Acad. Sci USA 101

      Pages: 4419-4424

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Secretion of heparanase protein is regulated by glycosylation in humantumor cell lines.2004

    • Author(s)
      Simizu, S., et al.
    • Journal Title

      J. Biol. Chem 279

      Pages: 2697-2703

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.2004

    • Author(s)
      Kubota, N., et al.
    • Journal Title

      J Clin Invest 114

      Pages: 917-927

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.2004

    • Author(s)
      Uekita, T., et al.
    • Journal Title

      J Biol Chem 279

      Pages: 12734-12743

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.2004

    • Author(s)
      Oliveira, C., et al.
    • Journal Title

      Hum Mol Genet 13

      Pages: 2303-2311

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synthesis of functional proteins by mixing peptide motifs.2004

    • Author(s)
      Saito, H., et al.
    • Journal Title

      Chem Biol 11

      Pages: 765-773

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Increased DNA methyltransferase I (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.2004

    • Author(s)
      Etoh, T., et al.
    • Journal Title

      Am. J. Pathol 164

      Pages: 689-699

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] High-grade dysplasia associated with fundic gland polyposis in a familial adenomtous polyposis patient with special reference to APC mutation profiles.2004

    • Author(s)
      Sekine, S., et al.
    • Journal Title

      Mod. Pathol 17

      Pages: 1421-1426

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma.2004

    • Author(s)
      Chuma, M., et al.
    • Journal Title

      J. Hepatol 41

      Pages: 629-636

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of enamel proteins and LEF1 in adamantinomatous craniopharyngioma : evidence for its odontogenic epithelial differentiation.2004

    • Author(s)
      Sekine, S., et al.
    • Journal Title

      Histopathology 45

      Pages: 573-579

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines.2004

    • Author(s)
      Tanami, H., et al.
    • Journal Title

      Oncogene 23

      Pages: 8796-8804

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Comparative genomic hybridization (CGH) arrays pave the way for identification of novel cancer-related genes.2004

    • Author(s)
      Inazawa, J., et al.
    • Journal Title

      Cancer Sci 95

      Pages: 559-563

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Amplification and overexpression of SKP2 are associated with metastasis of Non-Small-Cell lung cancers to lymph nodes.2004

    • Author(s)
      Yokoi, S., et al.
    • Journal Title

      Am J Pathol 165

      Pages: 175-180

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of PDZK1 within the lq12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma.2004

    • Author(s)
      Inoue, J., et al.
    • Journal Title

      Am J Pathol 165

      Pages: 71-81

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP 1B) expression by genetic and epigenetic mechanisms in esophageal squamous-cell carcinoma.2004

    • Author(s)
      Sonoda, I., et al.
    • Journal Title

      Cancer Res. 64

      Pages: 3741-3747

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Alteration in copy numbers of genes as a mechanism for acquired drug resistance.2004

    • Author(s)
      Yasui, K., et al.
    • Journal Title

      Cancer Res 64

      Pages: 1403-1410

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Amplification up-regulation and over-expression of C3G (CRK SH3 Domain-Binding Guanine Nucleotide-Releasing Factor) in lung cancer.2004

    • Author(s)
      Hirata, T., et al.
    • Journal Title

      J. Hum. Genet 49

      Pages: 290-295

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Up-regulation of CC Chemokine, CCL3L1 and receptors, CCR3 CCR5 in human glioblastoma multiforme that promotes cell growth.2004

    • Author(s)
      Kouno, J., et al.
    • Journal Title

      J. Neuro-Oncol 19

      Pages: 1296-1302

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of liver-cirrhosis nodules by analysis of gene-expression profiles and patterns of allelic loss.2004

    • Author(s)
      Nagai, H., et al.
    • Journal Title

      J. Hum. Genet 49

      Pages: 246-255

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of m-calpain is required for chromosome alignment on the metaphase plate during mitosis.2004

    • Author(s)
      Honda, S., et al.
    • Journal Title

      J. Biol. Chem 279

      Pages: 10615-10623

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint.2004

    • Author(s)
      Sudo T., et al.
    • Journal Title

      Cancer Res 64

      Pages: 2502-2508

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell-matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca2+ influx and PKC activation.2004

    • Author(s)
      Nagano, O., et al.
    • Journal Title

      J. Cell Biol 165

      Pages: 893-902

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function.2004

    • Author(s)
      Iida, S., et al.
    • Journal Title

      Oncogene 23

      Pages: 5266-5274

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents.2004

    • Author(s)
      Nitta, M., et al.
    • Journal Title

      Oncogene 23

      Pages: 6548-6558

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in esophageal cancer.2004

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Anticancer Res 24

      Pages: 3103-3108

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression.2004

    • Author(s)
      Oka, Y., et al.
    • Journal Title

      Proc Natl Acad Sci. USA 101

      Pages: 13885-13890

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' Tumor Gene WT1 in Primary Astrocytic Tumors.2004

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Cancer Sci 95

      Pages: 822-827

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma.2004

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Cancer Sci 95

      Pages: 583-587

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Absence of mutations in the Wilms' tumor gene WT1 in primary breast cancer.2004

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Jpn J Clin Oncol 34

      Pages: 74-77

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Absence of mutations in the Wilms' tumor gene wtl in de novo non-small cell lung cancers.2004

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Neoplasma 51

      Pages: 17-20

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] WT1 peptide vaccination combined with BCG-CWS is more efficient for tumor eradication than WT1 peptide vaccination alone.2004

    • Author(s)
      Nakajima, H., et al.
    • Journal Title

      Cancer Immunol Immunother 53

      Pages: 617-624

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] WT1 peptide-based immunotherapy for patients with lung cancer.2004

    • Author(s)
      Tsuboi, A., et al.
    • Journal Title

      Microbiol Immunol 48

      Pages: 175-184

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.2004

    • Author(s)
      Aoyama, T., et al.
    • Journal Title

      J. Biol. Chem 279

      Pages: 28789-28797

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of PDZK4 a novel gene with PDZ domains that is upregulated in synovial sarcomas.2004

    • Author(s)
      Nagayama, S., et al.
    • Journal Title

      Oncogene 23

      Pages: 1332221-1332221

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutation analysis of the RECQL4 gene in sporadic osteosarcomas.2004

    • Author(s)
      Nishijo, K., et al.
    • Journal Title

      Int. J. Cancer 111

      Pages: 367-372

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.2004

    • Author(s)
      Ochi, K., et al.
    • Journal Title

      Int. J. Oncology 64

      Pages: 347-355

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of the chondromodulin-I gene in chondrosarcomas.2004

    • Author(s)
      Aoyama, T., et al.
    • Journal Title

      Cancer Lett 204

      Pages: 21032-21032

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells.2004

    • Author(s)
      Imai, T., et al.
    • Journal Title

      Oncogene 22

      Pages: 9231-9242

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chromosome 12 frequently deleted in human pancreatic cancer may encode a tumor suppressor gene that suppresses angiogenesis.2004

    • Author(s)
      Yamanaka, S., et al.
    • Journal Title

      Lab. Invest 84

      Pages: 1339-1351

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular pathology of pancreatic cancer : in quest of tumor suppressor genes.2004

    • Author(s)
      Furukawa, T., et al.
    • Journal Title

      Pancreas 28

      Pages: 253-256

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genotyping of single nucleotide polymorphism using model-based clustering.2004

    • Author(s)
      Fujisawa, H., et al.
    • Journal Title

      Bioinformatics. 20

      Pages: 718-726

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relatively common mutations of the Bloom syndrome gene in the Japanese population.2004

    • Author(s)
      Kaneko, H., et al.
    • Journal Title

      Int. J. Mol. Med 14

      Pages: 439-442

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa using microsatellite markers.2004

    • Author(s)
      Kondo, H., et al.
    • Journal Title

      Invest Ophthalmol Vis Sci 45

      Pages: 4433-4439

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chromosome 10 and 17 deletions and p53 gene mutations in Thai patients with astrocytomas.2004

    • Author(s)
      Put-Ti-Noi, S., et al.
    • Journal Title

      Oncol Rep 1

      Pages: 207-211

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HLA genotyping is involved inter-individual variations of NK activity.2004

    • Author(s)
      Hayashi, T., et al.
    • Journal Title

      Immunology Medimond

      Pages: 21-25

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Allelic length of a CA dinucleotide repeat in the egfr gene correlates with the frequency of amplifications of this sequence - First results of an interethnic breast cancer study.2004

    • Author(s)
      Buerger, H., et al.
    • Journal Title

      J. Pathol 203

      Pages: 545-550

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregulation of p18INK4c.2004

    • Author(s)
      Matsuzaki, Y., et al.
    • Journal Title

      Oncogene 23

      Pages: 5409-5414

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Production of phytoene a carotenoid and induction of connexin 26 in transgenic mice carrying the phytoene synthase gene crtB.2004

    • Author(s)
      Satomi, S., et al.
    • Journal Title

      Biochem. Biophys. Res. Commun 320

      Pages: 398-401

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genistein induces Gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line.2004

    • Author(s)
      Oki, T., et al.
    • Journal Title

      FEBS Lett 577

      Pages: 55-59

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Isoliquiritigenin a flavonoid from licorice reduces prostaglandin E2 and nitric oxide causes apotosis and suppresses aberrant crypt foci development.2004

    • Author(s)
      Takahashi, T., et al.
    • Journal Title

      Cancer Sci 95

      Pages: 448-453

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Establishment of a new model of human multiple myeloma using NOD/SCID/_cnull (NOG) mice.2004

    • Author(s)
      Miyakawa, Y., et al.
    • Journal Title

      Biochem. Biophysical Res. Commun 313

      Pages: 258-262

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The subunits of glutamate cystein ligase enhance cisplatin resistance in human non-small cell lung cancer xenografts in vivo.2004

    • Author(s)
      Fujimori, S., et al.
    • Journal Title

      Int. J. Oncol 25

      Pages: 413-418

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] T Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.2004

    • Author(s)
      Ito, K., et al.
    • Journal Title

      nature 431

      Pages: 997-1002

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Bapx1 regulates patterning in the middle ear : Altered regulatory role in the transition from the proximal jaw during vertebrate evolution.2004

    • Author(s)
      Tucker, A., et al.
    • Journal Title

      Development 131

      Pages: 1235-1245

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Birth of parthenogenetic mice that can develop to adult.2004

    • Author(s)
      Kono, T., et al.
    • Journal Title

      nature 428

      Pages: 860-863

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Generation of pluripotent stem cells from neonatal mouse testis.2004

    • Author(s)
      Kanatsu-Shinohara, M., et al.
    • Journal Title

      Cell 119

      Pages: 1001-1012

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Thymus-leukemia antigen (TL) as a major histocompatibility complex (MHC) class lb molecule and tumor-specific antigen.2004

    • Author(s)
      Tsujimura, K., et al.
    • Journal Title

      Cancer Sci. 95

      Pages: 469-474

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling.2004

    • Author(s)
      Naito, M., et al.
    • Journal Title

      Mol. Cell. Biol 24

      Pages: 8418-8427

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Blockade of survival response to glucose deprivation for selective killing of tumor cells.2004

    • Author(s)
      Park, H-R., et al.
    • Journal Title

      J. Natl. Cancer Inst 96

      Pages: 1300-1310

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.2004

    • Author(s)
      Imai, Y., et al.
    • Journal Title

      Cancer Res 64

      Pages: 4346-4352

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells.2004

    • Author(s)
      Noguchi, K., et al.
    • Journal Title

      J. Biol. Chem 279

      Pages: 32716-32727

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Small in-frame deletion in the epidermal growth factor receptor as a target for ZD6474.2004

    • Author(s)
      Arao, T., et al.
    • Journal Title

      Cancer Res 64

      Pages: 9101-9104

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Comparison of gene-expression profiles between diffuse- and intestinal-type gastric cancers using a genome-wide cDNA microarray.2004

    • Author(s)
      Jinawath, N., et al.
    • Journal Title

      Oncogene 23

      Pages: 6830-6844

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Combination of intensive chemotherapy and imatinib can rapidly induce high-quality complete remission for a majority of patients with newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia.2004

    • Author(s)
      Towatari, M., et al.
    • Journal Title

      Blood 104

      Pages: 3507-3512

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Local hyperthermia combined with external irradiation for regional recurrent breast carcinoma.2004

    • Author(s)
      Li, G., et al.
    • Journal Title

      Int. J. Clin. Oncol 9

      Pages: 179-183

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Combination phase I study of nedaplatin and gemcitabine for advanced non-small-cell lung cancer.2004

    • Author(s)
      Kurata, T., et al.
    • Journal Title

      Br. J Cancer 90

      Pages: 2092-2096

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Functional subdomain in the ankyrin domain of tankyrase 1 required for poly (ADP-ribosyl) action of TRF1 and telomere elongation.2004

    • Author(s)
      Seimiya, H.
    • Journal Title

      Mol.Cell.Biol 24

      Pages: 1944-1955

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage.2004

    • Author(s)
      Shirasawa, S.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 13921-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Enhancement of serum-and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/Poliovirus Receptor/CD 155 through the Ras-Raf-MEK-ERK signaling.2004

    • Author(s)
      Kakunaga, S.
    • Journal Title

      J.Biol.Chem 279

      Pages: 36419-36425

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG.2004

    • Author(s)
      Fukuhara, T.
    • Journal Title

      J.Cell Biol 166

      Pages: 393-405

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.2004

    • Author(s)
      Hamamoto, R.
    • Journal Title

      Nat Cell Biol 6

      Pages: 731-740

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer : genome-wide gene-expression profiles of prostate cancers and PINs.2004

    • Author(s)
      Ashida, S.
    • Journal Title

      Cancer Res 64

      Pages: 5963-5972

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Gene-environment interaction between the smoking habit and polymorphisms in the DNA repair genes APE1 Asp 148Glu XRCC1 Arg399Gln in Japanese lung cancer risk.2004

    • Author(s)
      Ito, H.
    • Journal Title

      Carcinogenesis 25

      Pages: 1395-1401

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The CYP19 gene codon 39 Typ/Arg polymorphism increases breast cancer risk in subsets of premenopausal Japanese.2004

    • Author(s)
      Hirose, K.
    • Journal Title

      Cancer Epidemiol Biomarkers & Prev 13

      Pages: 1407-11

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Negative regulation of IFN-alpha/beta signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells.2004

    • Author(s)
      Honda, K.
    • Journal Title

      Proc Natl Acad Sci U S A 101

      Pages: 2416-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.2004

    • Author(s)
      Suzuki, H.
    • Journal Title

      nature Genet 36

      Pages: 417-422

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Oligo-astheno-teratozoospermia in mice lacking Cnot7 a regulator of retinoid X receptor beta.2004

    • Author(s)
      Nakamura, T.
    • Journal Title

      nature Genetics 36

      Pages: 528-533

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap.2004

    • Author(s)
      Yao, R.
    • Journal Title

      Oncogene 23

      Pages: 6023-6030

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of BMP and Activin Membrane-bound Inhibitor (BAMBI) an Inhibitor of Transforming Growth Factor {beta} Signaling as a Target of the b-Catenin Pathway in Colorectal Tumor Cells.2004

    • Author(s)
      Sekiya, T.
    • Journal Title

      J Biol Chem. 279

      Pages: 6840-6846

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Anteriorization of neural fate by ICAT a negative regulator of Wnt signaling.2004

    • Author(s)
      Satoh, K.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 8017-8021

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Perspectives on cancer immuno-epidemiology.2004

    • Author(s)
      Nakachi, K.
    • Journal Title

      Cancer Sci 95

      Pages: 921-929

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A Novel Snake Venom Vascular Endothelial Growth Factor (VEGF) Predominantly Induces Vascular Permeability through Preferential Signaling via VEGF Receptor-1.2004

    • Author(s)
      Takahashi, H.
    • Journal Title

      J.Biol.Chem 279

      Pages: 46304-46314

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Constitutive and induced CD44 shedding by ADAM-like proteases and membrane-type 1 matrix metalloproteinase.2004

    • Author(s)
      Nakamura, H.
    • Journal Title

      Cancer Res. 64

      Pages: 876-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-_superfamily and Runx proteins.2004

    • Author(s)
      Miyazono, K.
    • Journal Title

      Oncogene 23

      Pages: 4232-4237

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-_superfamily signaling.2004

    • Author(s)
      Mochizuki, T.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 31568-31574

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Combination chemotherapy CADO-CVP with radiotherapy and stem cell support can be beneficial for adolescent and adult estheisonneuroblastoma.2004

    • Author(s)
      Mishima Y.
    • Journal Title

      Cancer. 101

      Pages: 1437-44

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Paclitaxel administered weekly in patients with docetaxel-resistant metastatic breast cancer : A single-center study.2004

    • Author(s)
      Sawaki, M.
    • Journal Title

      Tumori 90

      Pages: 36-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Localization of hRad9, hHus1, hRad1 and hRad17 and caffeine-sensitive DNA replication at the alternative lengthening of telomeres-associated promyelocytic leukemia body.2004

    • Author(s)
      Nabetani, A.
    • Journal Title

      J.Biol.Chem 279

      Pages: 25849-25857

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Promotion of carcinogenesis and oxidative stress by dietary cholesterol in rat prostate.2004

    • Author(s)
      Homma, Y.
    • Journal Title

      Carcinogenesis 25

      Pages: 1011-1014

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Alternative mechanisms of gene amplification in human cancers.2004

    • Author(s)
      Kuwahara, Y.
    • Journal Title

      Genes Chromosomes & Cancer 41

      Pages: 125-132

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HST-1/FGF-4 plays a critical role in crypt cell survival and facilitates epithelial cell restitution and proliferation.2004

    • Author(s)
      Sasaki, H.
    • Journal Title

      Oncogene 23

      Pages: 3681-3688

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Familial essential thrombocythemia associated with a dominant-posotive activating mutation of the c-MPL gene which encodes for the receptor for thrombopoietin.2004

    • Author(s)
      Ding, J.
    • Journal Title

      Blood 103

      Pages: 4198-4200

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-cell leukemia/lymphoma.2004

    • Author(s)
      Ishida, T.
    • Journal Title

      Clin.Cancer Res 10

      Pages: 7529-7539

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A technique for noninvasive respiratory gated radiation treatment system based on a real time 3D ultrasound image correlation : a phantom study.2004

    • Author(s)
      Sawada, A.
    • Journal Title

      Med Phys 31

      Pages: 245-50

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Targeting hypoxic cancer cells with a protein prodrug is effective in experimental malignant ascites.2004

    • Author(s)
      Inoue, M.
    • Journal Title

      Int J Oncol 25

      Pages: 713-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.2004

    • Author(s)
      Kitajiri, S.
    • Journal Title

      J. Cell Biol 116

      Pages: 559-570

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Establishment and characterization of cultured epithelial cells lacking expression of ZO-1.2004

    • Author(s)
      Umeda, K.
    • Journal Title

      J.Biol.Chem 279

      Pages: 44785-44794

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Granulocyte-macrophage colony-stimulating factor is a keratinocyte-derived factor involved in regulating the proliferation and differentiation of neonatal mouse epidermal melanocytes in culture.2004

    • Author(s)
      Hirobe, T.
    • Journal Title

      Exp Cell Res. 297

      Pages: 593-606

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cdc42 and mDia3 regulate microtubule attachment to kinetochores.2004

    • Author(s)
      Yasuda, S.
    • Journal Title

      Nature 428

      Pages: 767-771

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Preferential cis-syn thymine dimer bypass by DNA polymerase occurs with biased fidelity.2004

    • Author(s)
      McCulloch S.D.
    • Journal Title

      nature 428

      Pages: 97-100

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] implications for fidelity and polymerase switching of translesion synthesis.2004

    • Author(s)
      Kusumoto, R.
    • Journal Title

      Genes Cells 9

      Pages: 1139-1150

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sensitization of tumor-associated endothelial cell apoptosis by the novel vascular-targeting agent ZD6126 in combination with cisplatin.2004

    • Author(s)
      Goto, H.
    • Journal Title

      Clin.Cancer Res 10

      Pages: 7671-7676

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prediction of sensitivity of advanced non-small cell lung cancers to gefitinib (Iressa ZD1839).2004

    • Author(s)
      Kakiuchi, S.
    • Journal Title

      Hum. Mol.Genet 13

      Pages: 3029-3043

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Myopathy phenotype in transgenic mice expressing mutated PABPN1 as a model of oculopharyngeal muscular dystrophy.2004

    • Author(s)
      Hino, H.
    • Journal Title

      Human Mol.Genet. 13

      Pages: 1-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Loss of PGC-specific expression of the orphan nuclear receptor ERR-results in reduction? of germ cell number in mouse embryos.2004

    • Author(s)
      Mitsunaga, K.
    • Journal Title

      Mech. Dev. 121

      Pages: 237-246

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Excess concordance of cancer incidence and lifestyles in married couples (Japan) : survival analysis of paired rate data.2004

    • Author(s)
      Izumi, S.
    • Journal Title

      Cancer Causes and Control 15

      Pages: 551-558

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Improving the efficiency of nested case-control studies of interaction by selecting controls using counter matching on exposure.2004

    • Author(s)
      Cologne, J.B.
    • Journal Title

      Int.J.Epidemiol 33

      Pages: 485-492

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of transcripts expressed preferentially in hemocytes of Ciona intestinalis that can be used as molecular markers.2004

    • Author(s)
      Wakoh, T.
    • Journal Title

      DNA Res 11

      Pages: 345-352

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Gene expression profiling identifies a set of transcripts that are up-regulated in human testicular seminoma.2004

    • Author(s)
      Yamada, S.
    • Journal Title

      DNA Res 11

      Pages: 335-344

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Immunity against mouse thymus-leukemia antigen (TL) protects against development of lymphomas induced by a chemical carcinogen N-butyl-N-nitrosourea.2004

    • Author(s)
      Tsujimura, K.
    • Journal Title

      Cancer Sci 95

      Pages: 914-919

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Pladienolides new substances from culture of Streptomyces platensis Mer-11107. III. In vitro and in vivo antitumor activities.2004

    • Author(s)
      Mizui, Y.
    • Journal Title

      J Antibiot (Tokyo) 57

      Pages: 188-196

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors.2004

    • Author(s)
      Fukazawa, H.
    • Journal Title

      Mol Cancer Ther 3

      Pages: 1281-1288

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Interaction between glucose-regulated destruction domain of DNA topoisomerase Ha and MPN domain of Jab1/CSN5.2004

    • Author(s)
      Yun, J.
    • Journal Title

      J Biol Chem 279

      Pages: 31296-31303

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synthesis and structure-activity relationships of thioflavone derivatives as specific inhibitors of the ERK-MAP kinase signaling pathway.2004

    • Author(s)
      Kataoka, T.
    • Journal Title

      Bioorg Med Chem 12

      Pages: 2397-2407

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Novel histone deacetylase inhibitors : cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones.2004

    • Author(s)
      Jose, B.
    • Journal Title

      Bioorg Med Chem. Lett 14

      Pages: 5343-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sensitivity to gefitinib (Iressa : ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/ Ark pathway for proliferation.2004

    • Author(s)
      Ono, M.
    • Journal Title

      Mol. Cancer Ther 3

      Pages: 465-472

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibition of lymphangiogenesis-related properties of murine lymphatic endothelial cells and lymph node metastasis of lung cancer by the matrix metalloproreinase inhibitor MMI270.2004

    • Author(s)
      Nakamura E.S.
    • Journal Title

      Cancer Sci 95

      Pages: 25-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Apollon ubiquitinates SMAC and caspase-9 and has an essential cytoprotection function.2004

    • Author(s)
      Hao, Y.
    • Journal Title

      Nat Cell Biol 6

      Pages: 849-60

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Gefitinib reverses breast cancer resistance protein-mediated drug resistance.2004

    • Author(s)
      Yanase, K.
    • Journal Title

      Mol Cancer Ther 3

      Pages: 1119-1125

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Structure of tyroscherin an antitumor antibiotic against IGF-1-dependent cells from Pseudallescheria sp.2004

    • Author(s)
      Hayakawa, Y.
    • Journal Title

      J. Antibiot 57

      Pages: 634-638

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex.2004

    • Author(s)
      Zhang, H-F.
    • Journal Title

      Cancer Res 64

      Pages: 1114-1121

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone Cdc37.2004

    • Author(s)
      Miyata, Y.
    • Journal Title

      Mol. Cell. Biol 24

      Pages: 4065-4074

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Telomere-bound TRF1 and TRF2 stall replication fork at telomeric repeats.2004

    • Author(s)
      Ohki, R.
    • Journal Title

      Nucl. Acids Res 32

      Pages: 1627-1637

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Polycomb group suppressor of zeste 12 links heterochromatin protein 1alpha and enhancer of zeste 22 22004

    • Author(s)
      Yamamoto, K.
    • Journal Title

      J Biol Chem 279

      Pages: 401-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] M-phase kinases inducephospho-dependent ubiquitination of somatic Wee1 by SCF β-TrCP.2004

    • Author(s)
      Watanabe, N.
    • Journal Title

      Proc. Natl. Acad. Sci USA 101

      Pages: 4419-4424

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Secretion of heparanase protein is regulated by glycosylation in humantumor cell lines.2004

    • Author(s)
      Simizu, S.
    • Journal Title

      J. Biol. Chem 279

      Pages: 2697-2703

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.2004

    • Author(s)
      Kubota, N.
    • Journal Title

      J Clin Invest 114

      Pages: 917-927

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.2004

    • Author(s)
      Uekita, T.
    • Journal Title

      J Biol Chem 279

      Pages: 12734-12743

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.2004

    • Author(s)
      Oliveira, C.
    • Journal Title

      Hum Mol Genet 13

      Pages: 2303-2311

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synthesis of functional proteins by mixing peptide motifs.2004

    • Author(s)
      Saito, H.
    • Journal Title

      Chem Biol 11

      Pages: 765-773

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.2004

    • Author(s)
      Etoh, T.
    • Journal Title

      Am. J. Pathol 164

      Pages: 689-699

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] High-grade dysplasia associated with fundic gland polyposis in a familial adenomtous polyposis patient with special reference to APC mutation profiles.2004

    • Author(s)
      Sekine, S.
    • Journal Title

      Mod. Pathol 17

      Pages: 1421-1426

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma.2004

    • Author(s)
      Chuma, M.
    • Journal Title

      J. Hepatol 41

      Pages: 629-636

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of enamel proteins and LEF1 in adamantinomatous craniopharyngioma : evidence for its odontogenic epithelial differentiation.2004

    • Author(s)
      Sekine, S.
    • Journal Title

      Histopathology 45

      Pages: 573-579

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines.2004

    • Author(s)
      Tanami, H.
    • Journal Title

      Oncogene 23

      Pages: 8796-804

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Comparative genomic hybridization (CGH) arrays pave the way for identification of novel cancer-related genes.2004

    • Author(s)
      Inazawa, J.
    • Journal Title

      Cancer Sci 95

      Pages: 559-63

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Amplification and overexpression of SKP2 are associated with metastasis of Non-Small-Cell lung cancers to lymph nodes.2004

    • Author(s)
      Yokoi, S.
    • Journal Title

      Am J Pathol 165

      Pages: 175-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma.2004

    • Author(s)
      Inoue, J.
    • Journal Title

      Am J Pathol 165

      Pages: 71-81

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP 1B) expression by genetic and epigenetic mechanisms in esophageal squamous-cell carcinoma.2004

    • Author(s)
      Sonoda, I.
    • Journal Title

      Cancer Res. 64

      Pages: 3741-47

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Alteration in copy numbers of genes as a mechanism for acquired drug resistance.2004

    • Author(s)
      Yasui, K.
    • Journal Title

      Cancer Res 64

      Pages: 1403-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Amplification up-regulation and over-expression of C3G (CRK SH3 Domain-Binding Guanine Nucleotide-Releasing Factor) in lung cancer.2004

    • Author(s)
      Hirata, T.
    • Journal Title

      J. Hum. Genet 49

      Pages: 290-295

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Up-regulation of CC Chemokine, CCL3L1 and receptors, CCR3 CCR5 in human glioblastoma multiforme that promotes cell growth.2004

    • Author(s)
      Kouno, J.
    • Journal Title

      J. Neuro-Oncol 19

      Pages: 1296-1302

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of liver-cirrhosis nodules by analysis of gene-expression profiles and patterns of allelic loss.2004

    • Author(s)
      Nagai, H.
    • Journal Title

      J. Hum. Genet 49

      Pages: 246-255

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of m-calpain is required for chromosome alignment on the metaphase plate during mitosis.2004

    • Author(s)
      Honda, S.
    • Journal Title

      J. Biol. Chem 279

      Pages: 10615-10623

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dependence of paclitaxel sensitivity on a functional spindle assembly checkpoint.2004

    • Author(s)
      Sudo T.
    • Journal Title

      Cancer Res 2004

      Pages: 2502-2508

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell-matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca2+ influx and PKC activation.2004

    • Author(s)
      Nagano, 0.
    • Journal Title

      J. Cell Biol 165

      Pages: 893-902

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function.2004

    • Author(s)
      Iida, S.
    • Journal Title

      Oncogene 23

      Pages: 5266-5274

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents.2004

    • Author(s)
      Nitta, M.
    • Journal Title

      Oncogene 23

      Pages: 6548-6558

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in esophageal cancer.2004

    • Author(s)
      Oji, Y.
    • Journal Title

      Anticancer Res 24

      Pages: 3103-3108

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression.2004

    • Author(s)
      Oka, Y.
    • Journal Title

      Proc Natl Acad Sci. USA 101

      Pages: 13885-13890

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' Tumor Gene WT1 in Primary Astrocytic Tumors.2004

    • Author(s)
      Oji, Y.
    • Journal Title

      Cancer Sci 95

      Pages: 822-827

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma.2004

    • Author(s)
      Oji, Y.
    • Journal Title

      Cancer Sci 95

      Pages: 583-587

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Absence of mutations in the Wilms' tumor gene WT1 in primary breast cancer.2004

    • Author(s)
      Oji, Y.
    • Journal Title

      Jpn J Clin Oncol 34

      Pages: 74-77

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Absence of mutations in the Wilms' tumor gene wt1 in de novo non-small cell lung cancers.2004

    • Author(s)
      Oji, Y.
    • Journal Title

      Neoplasma 51

      Pages: 17-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] WT1 peptide vaccination combined with BCG-CWS is more efficient for tumor eradication than WT1 peptide vaccination alone.2004

    • Author(s)
      Nakajima, H.
    • Journal Title

      Cancer Immunol Immunother 53

      Pages: 617-624

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] WT1 peptide-based immunotherapy for patients with lung cancer.2004

    • Author(s)
      Tsuboi, A.
    • Journal Title

      Microbiol Immunol 48

      Pages: 175-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.2004

    • Author(s)
      Aoyama, T.
    • Journal Title

      J. Biol. Chem 279

      Pages: 28789-97

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of PDZK4 a novel gene with PDZ domains that is upregulated in synovial sarcomas.2004

    • Author(s)
      Nagayama, S.
    • Journal Title

      Oncogene 23

      Pages: 5551-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutation analysis of the RECQL4 gene in sporadic osteosarcomas.2004

    • Author(s)
      Nishijo, K.
    • Journal Title

      Int. J. Cancer 111

      Pages: 367-72

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prediction of response to neoadjuvant chemotherapy for osteosarcoma by gene-expression profiles.2004

    • Author(s)
      Ochi, K.
    • Journal Title

      Int. J. Oncology 64

      Pages: 347-55

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of the chondromodulin-I gene in chondrosarcomas.2004

    • Author(s)
      Aoyama, T.
    • Journal Title

      Cancer Lett 204

      Pages: 61-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells.2004

    • Author(s)
      Imai, T.
    • Journal Title

      Oncogene 22

      Pages: 9231-42

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chromosome 12 frequently deleted in human pancreatic cancer may encode a tumor suppressor gene that suppresses angiogenesis.2004

    • Author(s)
      Yamanaka, S.
    • Journal Title

      Lab. Invest 84

      Pages: 1339-1351

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular pathology of pancreatic cancer : in quest of tumor suppressor genes.2004

    • Author(s)
      Furukawa, T.
    • Journal Title

      Pancreas 28

      Pages: 253-256

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genotyping of single nucleotide polymorphism using model-based clustering.2004

    • Author(s)
      Fujisawa, H.
    • Journal Title

      Bioinformatics. 20

      Pages: 718-726

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Relatively common mutations of the Bloom syndrome gene in the Japanese population.2004

    • Author(s)
      Kaneko, H.
    • Journal Title

      Int. J. Mol. Med 14

      Pages: 439-442

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A homozygosity-based search for mutations in patients with autosomal recessive retinitis pigmentosa using microsatellite markers.2004

    • Author(s)
      Kondo, H.
    • Journal Title

      Invest Ophthalmol Vis Sci 45

      Pages: 4433-4439

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chromosome 10 and 17 deletions and p53 gene mutations in Thai patients with astrocytomas.2004

    • Author(s)
      Put-Ti-Noi, S.
    • Journal Title

      Oncol Rep 1

      Pages: 207-211

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HLA genotyping is involved inter-individual variations of NK activity.2004

    • Author(s)
      Hayashi, T.
    • Journal Title

      Immunology 2004 (Skamene E ed.) Medimond S.r.l Bologna

      Pages: 21-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Allelic length of a CA dinucleotide repeat in the egfr gene correlates with the frequency of amplifications of this sequence-First results of an interethnic breast cancer study.2004

    • Author(s)
      Buerger, H.
    • Journal Title

      J. Pathol 203

      Pages: 545-550

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of protein kinase C promotes human cancer cell growth through downregulation of p18INK4c.2004

    • Author(s)
      Matsuzaki, Y.
    • Journal Title

      Oncogene 23

      Pages: 5409-5414

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Production of phytoene a carotenoid and induction of connexin 26 in transgenic mice carrying the phytoene synthase gene crtB.2004

    • Author(s)
      Satomi, S.
    • Journal Title

      Biochem. Biophys. Res. Commun 320

      Pages: 398-401

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genistein induces Gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line.2004

    • Author(s)
      Oki, T.
    • Journal Title

      FEBS Lett 577

      Pages: 55-59

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Isoliquiritigenin a flavonoid from licorice reduces prostaglandin E2 and nitric oxide causes apoptosis and suppresses aberrant crypt foci development.2004

    • Author(s)
      Takahashi, T.
    • Journal Title

      Cancer Sci 95

      Pages: 448-453

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Establishment of a new model of human multiple myeloma using NOD/SCID/_cnull (NOG) mice.2004

    • Author(s)
      Miyakawa, Y.
    • Journal Title

      Biochem. Biophysical Res. Commun 313

      Pages: 258-262

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The subunits of glutamate cystein ligase enhance cisplatin resistance in human non-small cell lung cancer xenografts in vivo.2004

    • Author(s)
      Fujimori, S.
    • Journal Title

      Int. J. Oncol 25

      Pages: 413-418

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells.2004

    • Author(s)
      Ito, K. T.
    • Journal Title

      nature 431

      Pages: 997-1002

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Bapx1 regulates patterning in the middle ear : Altered regulatory role in the transition from the proximal jaw during vertebrate evolution.2004

    • Author(s)
      Tucker, A.
    • Journal Title

      Development 131

      Pages: 1235-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Birth of parthenogenetic mice that can develop to adult.2004

    • Author(s)
      Kono, T.
    • Journal Title

      nature 428

      Pages: 860-863

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Generation of pluripotent stem cells from neonatal mouse testis.2004

    • Author(s)
      Kanatsu-Shinohara, M.
    • Journal Title

      Cell 119

      Pages: 1001-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Thymus-leukemia antigen (TL) as a major histocompatibility complex (MHC) class lb molecule and tumor-specific antigen.2004

    • Author(s)
      Tsujimura, K.
    • Journal Title

      Cancer Sci. 95

      Pages: 469-474

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling.2004

    • Author(s)
      Naito, M.
    • Journal Title

      Mol. Cell. Biol 24

      Pages: 8418-8427

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Blockade of survival response to glucose deprivation for selective killing of tumor cells.2004

    • Author(s)
      Park, H-R.
    • Journal Title

      J. Natl. Cancer Inst 96

      Pages: 1300-1310

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.2004

    • Author(s)
      Imai, Y.
    • Journal Title

      Cancer Res 64

      Pages: 4346-4352

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells.2004

    • Author(s)
      Noguchi, K.
    • Journal Title

      J. Biol. Chem 279

      Pages: 32716-32727

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Small in-frame deletion in the epidermal growth factor receptor as a target for ZD6474.2004

    • Author(s)
      Arao, T.
    • Journal Title

      Cancer Res 64

      Pages: 9101-9104

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Comparison of gene-expression profiles between diffuse-and intestinal-type gastric cancers using a genome-wide cDNA microarray.2004

    • Author(s)
      Jinawath, N.
    • Journal Title

      Oncogene 23

      Pages: 6830-6844

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Combination of intensive chemotherapy and imatinib can rapidly induce high-quality complete remission for a majority of patients with newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia.2004

    • Author(s)
      Towatari, M.
    • Journal Title

      Blood 104

      Pages: 3507-3512

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Local hyperthermia combined with external irradiation for regional recurrent breast carcinoma.2004

    • Author(s)
      Li, G.
    • Journal Title

      Int. J. Clin. Oncol 9

      Pages: 179-183

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Combination phase I study of nedaplatin and gemcitabine for advanced non-small-cell lung cancer.2004

    • Author(s)
      Kurata, T.
    • Journal Title

      Br. J Cancer 90

      Pages: 2092-2096

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage.2004

    • Author(s)
      Shirasawa S., et al.
    • Journal Title

      Proc.Natl.Acad.Sci., USA 101

      Pages: 13921-13926

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Enhancement of serum- and platelet-derived growth factor-induced cell proliferation by Necl-5/Tage4/Poliovirus Receptor/CD155 through the Ras-Raf-MEK-ERK signaling.2004

    • Author(s)
      Kakunaga, S., et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 36419-36425

    • Related Report
      2004 Annual Research Report
  • [Journal Article] SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells2004

    • Author(s)
      Hamamoto, R., et al.
    • Journal Title

      Nat Cell Biol. 6

      Pages: 731-740

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Gene-environment interaction between the smoking habit and polymorphisms in the DNA repair genes, APE1 Asp148Glu, XRCC1 Arg399Gln, in Japanese lung cancer risk.2004

    • Author(s)
      Ito, H., et al.
    • Journal Title

      Carcinogenesis 25

      Pages: 1395-1401

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Negative regulation of IFN-α/β signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells.2004

    • Author(s)
      Honda, K., et al.
    • Journal Title

      Proc.Natl.Acad.Sci., U S A 101

      Pages: 2416-2421

    • Related Report
      2004 Annual Research Report
  • [Journal Article] Chemoprevention of Cancer - Focusing on Clinical Trials.2003

    • Author(s)
      Kakizoe, T., et al.
    • Journal Title

      Jpn. J. Clin. Oncol. 33

      Pages: 421-442

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] TGF-β mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4.2003

    • Author(s)
      Ohshima T., et al.
    • Journal Title

      J Biol Chem. 278

      Pages: 50833-50842

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp 110b a potent transcriptional corepressor of retinoic acid receptor from the nucleus.2003

    • Author(s)
      Watashi K., et al.
    • Journal Title

      Mol Cell Biol. 23

      Pages: 7498-7509

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A set of loop-1 and -3 structures in the novel VEGF family member, VEGF-E (NZ-7) is essential for the activation of VEGFR-2 signaling.2003

    • Author(s)
      Kiba, A., et al.
    • Journal Title

      J. Biol. Chem 278

      Pages: 13453-13461

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Bone morphogenetic protein 4 mediates apoptosis of capillary endothelial cells during rat pupillary membrane regression.2003

    • Author(s)
      Kiyono, M., et al.
    • Journal Title

      Mol. Cell. Biol 23

      Pages: 4627-4636

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Can teatime increase one's lifetime.2003

    • Author(s)
      Nakachi, K., et al.
    • Journal Title

      Ageing Res. Reviews 44

      Pages: 1-10

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cyclic AMP inhibits translation of cyclin D3 in T-lymphocytes at the level of elongation by inducing eEF2-phosphorylation.2003

    • Author(s)
      Gutzkow, KB., et al.
    • Journal Title

      Cell Signalling 15

      Pages: 871-881

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Development of new topoisomerase II-targeting compounds as candidate anticancer drugs In : Toshiwo Andoh ed DNA Topoisomerases in Cancer Therapy-Present and Future.2003

    • Author(s)
      Andoh T., et al.
    • Journal Title

      Kluwer Academic/Plenum Publishers

      Pages: 167-188

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Specific blockade of the ERK pathway inhibits the invasiveness of tumor cells : down-regulation of matrix metalloproteinase-3/-9/-14 and CD44.2003

    • Author(s)
      Tanimura, S., et al.
    • Journal Title

      Biochem Biophys Res Commun 304

      Pages: 801-806

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cyclic tetrapeptides bearing sulfhydoryl group potently inhibit histone deacetylases.2003

    • Author(s)
      Nishino, N., et al.
    • Journal Title

      Org Lett 5

      Pages: 5079-5082

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synergistic effect of TNF-alpha in soluble vascular cell adhesion molecule-l-induced angiogenesis through alpha 4 integrins.2003

    • Author(s)
      Nakao, S., et al.
    • Journal Title

      J. Immunol 170

      Pages: 5704-5711

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] ZD 1839 a selective epidermal growth factor receptor tyrosine kinase inhibitor shows antimetastatic activity using a hepatocellular carcinoma model.2003

    • Author(s)
      Matsuo M., et al.
    • Journal Title

      Mol. Cancer Ther 2

      Pages: 557-561

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular targeting therapy of cancer : drug resistance apoptosis and survival signal.2003

    • Author(s)
      Tsuruo, T., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 15-21

    • NAID

      10016247833

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists.2003

    • Author(s)
      Sugimoto, Y., et al.
    • Journal Title

      Mol Cancer Ther 2

      Pages: 105-112

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Oximidine III a new antitumor antibiotic against transformed cells from Pseudomonas sp I Taxonomy, fermentation, isolation physico-chemical properties and biological activity.2003

    • Author(s)
      Hayakawa, Y., et al.
    • Journal Title

      J. Antibiot. 56

      Pages: 899-904

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutated APC and Asef are Involved in Migration of Colorectal Tumor Cells.2003

    • Author(s)
      Kawasaki, Y., et al.
    • Journal Title

      nature Cell Biology

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse.2003

    • Author(s)
      Takekuni, K., et al.
    • Journal Title

      J. Biol. Chem 278

      Pages: 5497-5500

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast.2003

    • Author(s)
      Miyoshi, T., et al.
    • Journal Title

      J Biol Chem. 17

      Pages: 1924-1931

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutated APC and Asef are Involved in Migration of Colorectal Tumor Cells.2003

    • Author(s)
      Kawasaki Y., et al.
    • Journal Title

      nature Cell Biology 5

      Pages: 211-215

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53RDLregulates p53-dependent apoptosis.2003

    • Author(s)
      Tanikawa, C., et al.
    • Journal Title

      nature Cell Biology 5

      Pages: 216-223

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.2003

    • Author(s)
      Kimura T., et al.
    • Journal Title

      nature Genetics 34

      Pages: 440-445

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of COX17 as a therapeutic target for non-small cell lung cancer.2003

    • Author(s)
      Suzuki, C., et al.
    • Journal Title

      Cancer Res 63

      Pages: 7038-7041

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Role of PlGF in the intra- andinter-molecular crolltalk between VEGF receptors Fltl and Flkl.2003

    • Author(s)
      Autiero, M., et al.
    • Journal Title

      nature Med. 9

      Pages: 936-943

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Tubular Formation byAngiopoietin-1 in Endothelial Cell/Fibroblast Co-culture is Dependent onEndogenous VEGF.2003

    • Author(s)
      Saito, M., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 782-790

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Blocking telomerase by dietary polyphenols is a mafor mechanism for limiting the growth of human cancer cells in vitro and in vivo.2003

    • Author(s)
      Naasani, I., et al.
    • Journal Title

      Cancer Res 63

      Pages: 824-830

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 2014 3 3 and cytoplasmic localozation.2003

    • Author(s)
      Fujita, N., et al.
    • Journal Title

      J. Biol. Chem 278

      Pages: 49254-49260

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Integration of IFN-α/β signalling to p53 responses in tumor suppression and antiviral defense.2003

    • Author(s)
      Takaoka, A., et al.
    • Journal Title

      Nature 424

      Pages: 516-523

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Integral role of Noxa in p53-mediated apoptotic response.2003

    • Author(s)
      Shibue, T., et al.
    • Journal Title

      EMBO Rep 17

      Pages: 2233-2238

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection.2003

    • Author(s)
      Honda, K., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 100

      Pages: 10872-10877

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a DAF-16transcriptional target gene scl-1 that regulates longevity and stressresistance in Caenorhabditis elegans.2003

    • Author(s)
      Ookuma, S., et al.
    • Journal Title

      Curr. Biol 13

      Pages: 427-431

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a consensus motif for Plk (polo-like kinase)phosphorylation reveals Mytl as a Plk1 substrate.2003

    • Author(s)
      Nakajima, H., et al.
    • Journal Title

      J. Biol. Chem. 278

      Pages: 25277-25480

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dynamic behavior of paired claudin strands within apposing plasma membranes.2003

    • Author(s)
      Sasaki, H., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 100

      Pages: 3971-3976

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice.2003

    • Author(s)
      Nitta, T., et al.
    • Journal Title

      J.Cell Biol 161

      Pages: 653-660

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Claudins in Caenorhabditis elegans : their distribution and barrier function in the epithelium.2003

    • Author(s)
      Asano, A., et al.
    • Journal Title

      Curr. Biol 13

      Pages: 1042-1046

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Stable inheritance of telomere chromatin structure and function in the absence of telomeric repeats.2003

    • Author(s)
      Sadaie, M., et al.
    • Journal Title

      Genes Dev 17

      Pages: 2271-2282

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] DOCK2 isessential for antigen-induced translocation of TCR and lipid rafts but notPKC-theta and LFA-1 in T cells.2003

    • Author(s)
      Sanui T., et al.
    • Journal Title

      Immunity 19

      Pages: 119-129

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Epoxycyclohexenone inhibits Fas-mediated apoptosis by blockingactivation of pro-caspase-8 in death-inducing signaling complex.2003

    • Author(s)
      Miyake, Y., et al.
    • Journal Title

      J.Biol. Chem 278

      Pages: 11213-11220

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Crucial roles of Brnl in distal tubule formation and function in mouse kidney.2003

    • Author(s)
      Nakai, S., et al.
    • Journal Title

      Development 130

      Pages: 4751-4759

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] ARF tumor suppressor induces mitochondria-dependent apoptosis by modulation of mitochondrial Bcl-2 family proteins.2003

    • Author(s)
      Nakazawa, Y., et al.
    • Journal Title

      J Biol Chem 278

      Pages: 27888-27895

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity.2003

    • Author(s)
      Matsumoto, M., et al.
    • Journal Title

      J Clin Invest 112

      Pages: 935-944

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Monoclonal antibodies with defined recognition sequences in the stem region of CD44 : detection of differential glycosyiation of CD44 between tumor and stromal cells in tissue.2003

    • Author(s)
      Matsuki, H., et al.
    • Journal Title

      Cancer Res 63

      Pages: 8278-8283

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Clusterin an abundant serum factor is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils.2003

    • Author(s)
      Matsuda, A., et al.
    • Journal Title

      J Biol Chem 278

      Pages: 36350-36357

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Simultaneous on/off regulation of transgenes located on a mammalian chromosome with Cre-expressing adenovirus and a mutant loxP.2003

    • Author(s)
      Kondo, S., et al.
    • Journal Title

      Nucleic Acids Res 31

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Epigenetic inactivation of CHFR in human tumors.2003

    • Author(s)
      Toyota, M., et al.
    • Journal Title

      Proc Natl Acad Sci USA 100

      Pages: 7818-7823

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dynamic behavior of paired claudin strands within apposing plasma membranes.2003

    • Author(s)
      Sasaki, H., et al.
    • Journal Title

      Proc Natl Acad Sci USA 100

      Pages: 3971-3976

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A large-scale gene expression comparison of microdissected small-sized endometrial cancers with or without hyperplasia matched to same-patient normal tissue.2003

    • Author(s)
      Sugiyama, Y., et al.
    • Journal Title

      Clin Cancer Res 9

      Pages: 5589-5600

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.2003

    • Author(s)
      Dan, S., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 1074-1082

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rapid discovery and identification of a tissue-specific tumor biomarker from 39 human cancer cell lines using the SELDI ProteinChip platfrom.2003

    • Author(s)
      Shiwa, M., et al.
    • Journal Title

      Biochem Biophys Res Commun 309

      Pages: 18-25

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Panel of human cancer cell lines provides valuable database for drug discovery and bioinformatics.2003

    • Author(s)
      Yamori, T., et al.
    • Journal Title

      Cancer Chemother Pharmacol 1

      Pages: 74-79

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression profiling in multistage hepatocarcinogenesis : identification of HSP70 as a molecular marker of early Hepatocelluar carcinoma.2003

    • Author(s)
      Chuma, M., et al.
    • Journal Title

      Hepatology 37

      Pages: 198-207

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of KIT in chromophobe renal cell carcinoma.2003

    • Author(s)
      Yamazaki, K., et al.
    • Journal Title

      Oncogene 22

      Pages: 847-852

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of orphan G-protein-coupled receptor, Gpr49 in human hepatocellular carcinomas with β-catenin mutations.2003

    • Author(s)
      Yamamoto Y Sakamoto., et al.
    • Journal Title

      Hepatology 37

      Pages: 528-533

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Increased protein expression of DNA methyltransferase (DNMT) l is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.2003

    • Author(s)
      Saito, Y., et al.
    • Journal Title

      Int. J. Cancer 105

      Pages: 527-532

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of liver-intestine cadherin and its possible interaction with galectin -3 in ductal adenocarcinoma of the panreas.2003

    • Author(s)
      Takamura, M., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 425-430

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] β-catenin mutations in pulmonary blastomas : association with morule formation.2003

    • Author(s)
      Sekine, S., et al.
    • Journal Title

      J. Pathol 200

      Pages: 214-221

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] β-catenin mutations are frequent in calcifying odontogenic cysts but rare in ameloblastomas.2003

    • Author(s)
      Sekine, S., et al.
    • Journal Title

      Am. J. Pathol 163

      Pages: 1707-1712

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Increased DNA methyltransferase l protein expression in human transitional cell carcinoma of the bladder.2003

    • Author(s)
      Nakagawa, T., et al.
    • Journal Title

      J. Urol 170

      Pages: 2463-2466

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Possible involvement of tetraspanin CO-029 in hematogenous intrahepatic metastasis of liver cancer cells.2003

    • Author(s)
      Kanetaka, K., et al.
    • Journal Title

      J. Gastroenterol. Hepatol 18

      Pages: 1309-1314

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Unfavorable prognostic factors associated with high frequency of microsatellite instability and comparative genomic hybridization analysis in endometrial cancer.2003

    • Author(s)
      Hirasawa, A., et al.
    • Journal Title

      Clin Cancer Res 15

      Pages: 5675-5682

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers.2003

    • Author(s)
      Yokoi, S., et al.
    • Journal Title

      Clin Cancer Res 15

      Pages: 4705-4713

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas.2003

    • Author(s)
      Okamoto, H., et al.
    • Journal Title

      Hepatology 38

      Pages: 1242-1249

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of ZASC1 encoding a Kruppel-like zinc finger protein as a novel target for 3q26 amplification in esophageal squamous cell carcinomas.2003

    • Author(s)
      Imoto, I., et al.
    • Journal Title

      Cancer Res 63

      Pages: 1383326-1383326

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Down-regulation of SKP2 induces apoptosis in lung-cancer cells.2003

    • Author(s)
      Yokoi, S., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 344-349

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association of 17q21-q24 Gain in Ovarian Clear Cell Adenocarcinomas with Poor Prognosis and Identification of PPM1D and APPBP2 as Likely Amplification Targets.2003

    • Author(s)
      Hirasawa, A., et al.
    • Journal Title

      Clin Cancer Res 9

      Pages: 1995-2004

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] PPM1D is a potential target for 17q gain in neuroblastoma.2003

    • Author(s)
      Saito-Ohara, F., et al.
    • Journal Title

      Cancer Res 63

      Pages: 1876-1883

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell culture in esophageal squamous cell carcinoma and the association with molecular markers.2003

    • Author(s)
      Shimada, Y., et al.
    • Journal Title

      Clin Cancer Res 9

      Pages: 243-249

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Presenilin-dependent g-secretase activity mediates the intramembranous cleavage of CD44.2003

    • Author(s)
      Murakami, D., et al.
    • Journal Title

      Oncogegne 22

      Pages: 1511-1516

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Aurora-A and an interacting activator the LIM protein Ajuba are required for mitotic commitment in human cells.2003

    • Author(s)
      Hirota, T., et al.
    • Journal Title

      Cell 114

      Pages: 585-598

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells.2003

    • Author(s)
      Marumoto, T., et al.
    • Journal Title

      J. Biol. Chem 278

      Pages: 51786-51795

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Aurora-A-dependent phosphorylation of CENP-A in prophase is essential for concentration of Aurora-B at inner centromeres and for kinetochore function.2003

    • Author(s)
      Kunitoku, N., et al.
    • Journal Title

      Dev. Cell 5

      Pages: 853-864

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Monitoring minimal residual disease in leukemia using real-time quantitative polymerase chain reaction for Wilms tumor gene (WT1).2003

    • Author(s)
      Tamaki, H., et al.
    • Journal Title

      Int J Hematol 78

      Pages: 349-356

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer.2003

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 606-611

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in colorectal adenocarcinoma.2003

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 712-717

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WTl in head and neck squamous cell carcinoma.2003

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 523-529

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] WT1 peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndome (MDS) or MDS with myelofibrosis.2003

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      Oka, Y., et al.
    • Journal Title

      Int J Hematol 78

      Pages: 56-61

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in human bone and soft-tissue sarcomas.2003

    • Author(s)
      Ueda, T., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 271-276

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia.2003

    • Author(s)
      Ogawa, H., et al.
    • Journal Title

      Blood 101

      Pages: 1698-1704

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by antimicrotubule agents in human lung cancers.2003

    • Author(s)
      Masuda, A., et al.
    • Journal Title

      Am. J. Pathol 163

      Pages: 1106-1119

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase reduced folate carrier and thymidylate synthase mRNA expression in osteosarcoma.2003

    • Author(s)
      Sowers, R., et al.
    • Journal Title

      Mol. Cancer Ther. 2

      Pages: 535-541

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Altered expression of the receptor and ligand in the TGF beta signaling pathway in diffusely infiltrating colon carcinoma.2003

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    • Journal Title

      Anticancer Res 22

      Pages: 3545-3554

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inserting chromosome 18 into pancreatic cancer cells switches them to a dormant metastatic phenotype.2003

    • Author(s)
      Lefter LP., et al.
    • Journal Title

      Clin. Cancer Res 9

      Pages: 5044-5052

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.2003

    • Author(s)
      Duda DG., et al.
    • Journal Title

      Oncogene 22

      Pages: 6857-6864

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer.2003

    • Author(s)
      Furukawa, T., et al.
    • Journal Title

      Am. J. Pathol. 162

      Pages: 1807-1815

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.2003

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      Okada, K., et al.
    • Journal Title

      Int J Oncol 23

      Pages: 1615-1635

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular detection of von Hippel-Lindau gene mutations in urine and lymph node samples in patients with renal cell carcinoma : potential biomarkers for early diagnosis and postoperative metastatic status.2003

    • Author(s)
      Ashida, S., et al.
    • Journal Title

      J Urol 169

      Pages: 2089-2093

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9.2003

    • Author(s)
      Yoshida, K., et al.
    • Journal Title

      EMBO J 22

      Pages: 1431-1441

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic polymorphism at the 5' regulatory region of MDR1 and its association with inter-individual variation of expression level in colon.2003

    • Author(s)
      Taniguchi, S., et al.
    • Journal Title

      Mol Cancer Ther 12

      Pages: 1351-1359

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Frizzled 4 gene (FZD4) mutations in patients with familial exudative vitreoretinopathy with variable expressivity.2003

    • Author(s)
      Kondo, H., et al.
    • Journal Title

      Br J Ophthalmol 87

      Pages: 1291-1295

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Single-stranded conformational polymorphism analysis using automated capillary array electrophoresis apparatus.2003

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      Baba, S., et al.
    • Journal Title

      BioTechniques 34

      Pages: 746-750

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] SNP detection and allele frequency determination by SSCP.2003

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    • Journal Title

      Methods Mol Biol 212

      Pages: 37-46

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HLA haplotype is associated with diabetes among atomic bomb survivors.2003

    • Author(s)
      Hayashi, T., et al.
    • Journal Title

      Hum. Immunol 64

      Pages: 910-916

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Isoliquiritigenin inhibits the growth of prostate cancer.2003

    • Author(s)
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    • Journal Title

      Eur. Urology 43

      Pages: 580-586

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] H-ras mutations at codon 61 or 13 in tumors initiated with a NO donor in mouse skin.2003

    • Author(s)
      Satomi, Y., et al.
    • Journal Title

      Cancer Lett 196

      Pages: 17-22

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression profiling in ovarian clear cell carcinoma : identification of hepatocyte nuclear actor-1β as a molecular marker and a possible molecular target for therapy of ovarian clear cell carcinoma.2003

    • Author(s)
      Tsuchiya, A., et al.
    • Journal Title

      Am. J. Pathol 163

      Pages: 2503-2512

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice form Atherosclerosis.2003

    • Author(s)
      Yamauchi, T., et al.
    • Journal Title

      J. Biol. Chem. 278

      Pages: 2461-2468

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor β-induced repression of c-myc.2003

    • Author(s)
      Sasaki, T., et al.
    • Journal Title

      Cancer Res. 63

      Pages: 801-806

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Effects of Donor Cell Type and Genotype on the Efficiency of Mouse Somatic Cell Cloning.2003

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      Inoue, K., et al.
    • Journal Title

      Biol Reprod. 69

      Pages: 1394-1400

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells.2003

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      Kanatsu-Shinohara, M., et al.
    • Journal Title

      Biol Reprod. 69

      Pages: 612-616

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis.2003

    • Author(s)
      Chida, K., et al.
    • Journal Title

      Cancer Res. 15

      Pages: 2404-2408

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Immunomic analysis of human sarcoma.2003

    • Author(s)
      Lee, S-Y., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 100

      Pages: 2561-2656

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H469 cells : Therapeutic effect of a novel polyarginine-conjugated smac peptide.2003

    • Author(s)
      Yang, L., et al.
    • Journal Title

      Cancer Res 63

      Pages: 831-837

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Single amino acid substitutions in the transmembrane domains of breast cancer resistance protein (BCRP) alter cross resistance patterns in the transfectants.2003

    • Author(s)
      Miwa, M., et al.
    • Journal Title

      Int. J. Cancer 107

      Pages: 757-767

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Natural product origins of Hsp90 inhibitors Hsp90 Molecular Chaperon Inhibitors : Opportunities and Challenges.2003

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      Uehara, Y., et al.
    • Journal Title

      Current Cancer Drug Targets 3

      Pages: 319-324

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Translational and clinical studies of target based drugs.2003

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    • Journal Title

      Int. J. Clin. Oncol 8

      Pages: 187-192

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Clinical significance of CCR4 expression in adult T-cell leukemia/lymphoma : its close association with skin involvement and unfavorable outcome.2003

    • Author(s)
      Ishida, T., et al.
    • Journal Title

      Clin. Cancer Res 9

      Pages: 3625-3634

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multiple primary cancer : an experience at the Cancer Institute Hospital with special reference to colorectal cancer.2003

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      Ueno, M., et al.
    • Journal Title

      Int. J. Clin. Oncol 8

      Pages: 162-167

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Elevation of circulating plasma cytokines in cancer patients with high plasma parathyroid hormone-related protein levels Endocr Relat2003

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      Takahashi, S., et al.
    • Journal Title

      Cancer 10

      Pages: 403-407

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prediction of response to imatinib by cDNA microarray analysis.2003

    • Author(s)
      Ohno, R., et al.
    • Journal Title

      Semin. Hematol 40

      Pages: 42-49

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Late skin and subcutaneous soft tissue changes after 10-gy boost for breast conserving therapy.2003

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      Okumura S., et al.
    • Journal Title

      Breast Cancer 10

      Pages: 129-133

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer.2003

    • Author(s)
      Fukuoka, M., et al.
    • Journal Title

      J. Clin. Oncol 21

      Pages: 2237-2246

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Combined therapy with a new bisphosphonate minodronate (YM529) and chemotherapy for multiple organ metastases of small cell lung cancer cells in severe combined immunodeficient mice.2003

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      Yano, S., et al.
    • Journal Title

      Clin. Cancer Res 9

      Pages: 5380-5385

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A loss of function mutation in WISP3 derived from microsatellite unstable gastric carcinoma.2003

    • Author(s)
      Tanaka, S., et al.
    • Journal Title

      Gastroenterology 125

      Pages: 1563-1564

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chemoprevention of Cancer - Focusing on Clinical Trials.2003

    • Author(s)
      Kakizoe, T.
    • Journal Title

      Jpn. J. Clin. Oncol. 33

      Pages: 421-442

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] TGF-β mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4.2003

    • Author(s)
      Ohshima, T
    • Journal Title

      J Biol Chem. 278

      Pages: 50833-50842

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp 110b a potent transcriptional corepressor of retinoic acid receptor from the nucleus.2003

    • Author(s)
      Watashi, K
    • Journal Title

      Mol Cell Biol. 23

      Pages: 7498-7509

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A set of loop-1 and-3 structures in the novel VEGF family member, VEGF-E(NZ-7) is essential for the activation of VEGFR-2 signaling.2003

    • Author(s)
      Kiba, A.
    • Journal Title

      J.Biol.Chem 278

      Pages: 13453-13461

    • Description
      「研究成果報告書概要(欧文)」より
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      2005 Final Research Report Summary
  • [Journal Article] Bone morphogenetic protein 4 mediates apoptosis of capillary endothelial cells during rat papillary membrane regression.2003

    • Author(s)
      Kiyono, M.
    • Journal Title

      Mol.Cell.Biol 23

      Pages: 4627-4636

    • Description
      「研究成果報告書概要(欧文)」より
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      2005 Final Research Report Summary
  • [Journal Article] Can teatime increase one's lifetime.2003

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    • Journal Title

      Ageing Res.Reviews 44

      Pages: 1-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cyclic AMP inhibits translation of cyclin D3 in T-lymphocytes at the level of elongation by inducing eEF2-phosphorylation.2003

    • Author(s)
      Gutzkow, KB.
    • Journal Title

      Cell Signaling 15

      Pages: 871-881

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Development of new topoisomerase II-targeting compounds as candidate anticancer drugs. In : Toshiwo Andoh ed DNA Topoisomerases in Cancer Therapy-Present and Future.2003

    • Author(s)
      Andoh, T.
    • Journal Title

      Kluwer Academic/Plenum Publishers

      Pages: 167-188

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Specific blockade of the ERK pathway inhibits the invasiveness of tumor cells : down-regulation of matrix metalloproteinase-3/-9/-14 and CD44.2003

    • Author(s)
      Tanimura, S.
    • Journal Title

      Biochem Biophys Res Commun 304

      Pages: 801-806

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cyclic tetrapeptides bearing sulfhydoryl group potently inhibit histone deacetylases.2003

    • Author(s)
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    • Journal Title

      Org Lett 5

      Pages: 5079-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Synergistic effect of TNF-alpha in soluble vascular cell adhesion molecule-1-induced angiogenesis through alpha 4 integrins.2003

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    • Journal Title

      J. Immunol 170

      Pages: 5704-5711

    • Description
      「研究成果報告書概要(欧文)」より
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      2005 Final Research Report Summary
  • [Journal Article] ZD 1839 a selective epidermal growth factor receptor tyrosine kinase inhibitor shows antimetastatic activity using a hepatocellular carcinoma model.2003

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      Matsuo, M.
    • Journal Title

      2

      Pages: 557-561

    • Description
      「研究成果報告書概要(欧文)」より
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      2005 Final Research Report Summary
  • [Journal Article] Molecular targeting therapy of cancer : drug resistance apoptosis and survival signal.2003

    • Author(s)
      Tsuruo, T.
    • Journal Title

      Cancer Sci 94

      Pages: 15-21

    • NAID

      10016247833

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Reversal of breast cancer resistance protein-mediated drug resistance by estrogen antagonists and agonists.2003

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      Mol Cancer Ther 2

      Pages: 105-112

    • Description
      「研究成果報告書概要(欧文)」より
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      2005 Final Research Report Summary
  • [Journal Article] Oximidine III a new antitumor antibiotic against transformed cells from Pseudomonas sp. I. Taxonomy, fermentation, isolation physico-chemical properties and biological activity.2003

    • Author(s)
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    • Journal Title

      J. Antibiot. 56

      Pages: 899-904

    • Description
      「研究成果報告書概要(欧文)」より
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      2005 Final Research Report Summary
  • [Journal Article] Mutated APC and Asef are Involved in Migration of Colorectal Tumor Cells.2003

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      Kawasaki, Y.
    • Journal Title

      nature Cell Biology DOI10.1038/Ncb937

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Direct binding of cell polarity protein PAR-3 to cell-cell adhesion molecule nectin at neuroepithelial cells of developing mouse.2003

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    • Journal Title

      J. Biol. Chem 278

      Pages: 5497-5500

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast.2003

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      Miyoshi, T
    • Journal Title

      J Biol Chem 17, 27

      Pages: 1924-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutated APC and Asef are Involved in Migration of Colorectal Tumor Cells.2003

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      Y.Kawasaki
    • Journal Title

      nature Cell Biology 5

      Pages: 211-215

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53RDLregulates p53-dependent apoptosis.2003

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      Tanikawa, C
    • Journal Title

      nature Cell Biology 5

      Pages: 216-223

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools.2003

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      T.Kimura
    • Journal Title

      nature Genetics 34

      Pages: 440-445

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of COX17 as a therapeutic target for non-small cell lung cancer.2003

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    • Journal Title

      Cancer Res 63

      Pages: 7038-7041

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Role of P1GF in the intra-and inter-molecular crolltalk between VEGF receptors Flt1 and Flk1.2003

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      Autiero, M.
    • Journal Title

      nature Med. 9

      Pages: 936-943

    • Description
      「研究成果報告書概要(欧文)」より
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      2005 Final Research Report Summary
  • [Journal Article] Tubular Formation by Angiopoietin-1 in Endothelial Cell/Fibroblast Co-culture is Dependent on Endogenous VEGF.2003

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      Saito, M.
    • Journal Title

      Cancer Science 94

      Pages: 782-790

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Blocking telomerase by dietary polyphenols is a mafor mechanism for limiting the growth of human cancer cells in vitro and in vivo.2003

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      Naasani, I.
    • Journal Title

      Cancer Res 63

      Pages: 824-830

    • Description
      「研究成果報告書概要(欧文)」より
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      2005 Final Research Report Summary
  • [Journal Article] Phosphorylation of p27Kip1 at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 2014.3.3 and cytoplasmic localization.2003

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      J. Biol. Chem 278

      Pages: 49254-49260

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
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  • [Journal Article] Integration of IFN-α/β signaling to p53 responses in tumor suppression and antiviral defense.2003

    • Author(s)
      Takaoka, A.
    • Journal Title

      Nature 424

      Pages: 516-523

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Integral role of Noxa in p53-mediated apoptotic response.2003

    • Author(s)
      Shibue, T.
    • Journal Title

      Genes. Dev 17

      Pages: 2233-2238

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Selective contribution of IFN-α/β signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection.2003

    • Author(s)
      Honda, K.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 100

      Pages: 10872-10877

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a DAF-16transcriptional target gene scl-1 that regulates longevity and stressresistance in Caenorhabditis elegans.2003

    • Author(s)
      Ookuma, S.
    • Journal Title

      Curr. Biol 13

      Pages: 427-431

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a consensus motif for Plk (polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.2003

    • Author(s)
      Nakajima, H.
    • Journal Title

      J. Biol. Chem. 278

      Pages: 25277-25480

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dynamic behavior of paired claudin strands within apposing plasma membranes.2003

    • Author(s)
      Sasaki, H.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 3971-3976

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice.2003

    • Author(s)
      Nitta, T.
    • Journal Title

      J. Cell Biol 161

      Pages: 653-660

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Claudins in Caenorhabditis elegans : their distribution and barrier function in the epithelium.2003

    • Author(s)
      Asano, A.
    • Journal Title

      Curr. Biol 13

      Pages: 1042-1046

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Stable inheritance of telomere chromatin structure and function in the absence of telomeric repeats.2003

    • Author(s)
      Sadaie, M.
    • Journal Title

      Genes Dev 17

      Pages: 2271-2282

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] DOCK2 inessential for antigen-induced translocation of TCR and lipid rafts but not PKC-theta and LFA-1 in T cells.2003

    • Author(s)
      Sanui, T.
    • Journal Title

      Immunity 19

      Pages: 119-29

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Epoxycyclohexenone inhibits Fas-mediated apoptosis by blocking activation of pro-caspase-8 in death-inducing signaling complex.2003

    • Author(s)
      Miyake, Y.
    • Journal Title

      J. Biol. Chem 278

      Pages: 11213-11220

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Crucial roles of Brn1 in distal tubule formation and function in mouse kidney.2003

    • Author(s)
      Nakai, S.
    • Journal Title

      Development 130

      Pages: 4751-4759

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] ARF tumor suppressor induces mitochondria-dependent apoptosis by modulation of mitochondrial Bcl-2 family proteins.2003

    • Author(s)
      Nakazawa, Y.
    • Journal Title

      J Biol Chem 278

      Pages: 27888-27895

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] PKC λ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity.2003

    • Author(s)
      Matsumoto, M.
    • Journal Title

      J Clin Invest 112

      Pages: 935-944

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Monoclonal antibodies with defined recognition sequences in the stem region of CD44 : detection of differential glycosylation of CD44 between tumor and stromal cells in tissue.2003

    • Author(s)
      Matsuki, H
    • Journal Title

      Cancer Res 63

      Pages: 8278-8283

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Clusterin an abundant serum factor is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils.2003

    • Author(s)
      Matsuda, A.
    • Journal Title

      J Biol Chem 278

      Pages: 36350-36357

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Simultaneous on/off regulation of transgenes located on a mammalian chromosome with Cre-expressing adenovirus and a mutant loxP.2003

    • Author(s)
      Kondo, S
    • Journal Title

      Nucleic Acids Res 31, e76

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A large-scale gene expression comparison of microdissected small-sized endometrial cancers with or without hyperplasia matched to same-patient normal tissue.2003

    • Author(s)
      Sugiyama, Y.
    • Journal Title

      Clin Cancer Res 9

      Pages: 5589-5600

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of candidate predictive markers of anticancer drug sensitivity using a panel of human cancer cell lines.2003

    • Author(s)
      Dan, S.
    • Journal Title

      Cancer Sci 94

      Pages: 1074-1082

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rapid discovery and identification of a tissue-specific tumor biomarker from 39 human cancer cell lines using the SELDI Protein Chip platform.2003

    • Author(s)
      Shiwa, M.
    • Journal Title

      Biochem Biophys Res Commun 309

      Pages: 18-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Panel of human cancer cell lines provides valuable database for drug discovery and bioinformatics.2003

    • Author(s)
      Yamori, T.
    • Journal Title

      Cancer Chemother Pharmacol 52 Suppl1

      Pages: 74-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression profiling in multistage hepatocarcinogenesis : identification of HSP70 as a molecular marker of early hepatocellular carcinoma.2003

    • Author(s)
      Chuma, M.
    • Journal Title

      Hepatology 37

      Pages: 198-207

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of KIT in chromophobe renal cell carcinoma.2003

    • Author(s)
      Yamazaki, K.
    • Journal Title

      Oncogene 22

      Pages: 847-852

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of orphan G-protein-coupled receptor, Gpr49 in human hepatocellular carcinomas with β-catenin mutations.2003

    • Author(s)
      Yamamoto, Y, Sakamoto, M, Fujii, G, Tsuiji, H, Kanetaka, K, Asaka, M.
    • Journal Title

      Hepatology 37

      Pages: 528-533

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas.2003

    • Author(s)
      Saito, Y.
    • Journal Title

      Int. J. Cancer 105

      Pages: 527-532

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of liver-intestine cadherin and its possible interaction with galectin-3 in ductal adenocarcinoma of the panreas.2003

    • Author(s)
      Takamura, M.
    • Journal Title

      Cancer Sci 94

      Pages: 425-430

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] β-catenin mutations in pulmonary blastomas : association with morule formation.2003

    • Author(s)
      Sekine, S.
    • Journal Title

      J. Pathol 200

      Pages: 214-221

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] β-catenin mutations are frequent in calcifying odontogenic cysts but rare in ameloblastomas.2003

    • Author(s)
      Sekine, S.
    • Journal Title

      Am. J. Pathol 163

      Pages: 1707-1712

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Increased DNA methyltransferase 1 protein expression in human transitional cell carcinoma of the bladder.2003

    • Author(s)
      Nakagawa, T.
    • Journal Title

      J. Urol 170

      Pages: 2463-2466

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Possible involvement of tetraspanin CO-029 in hematogenous intrahepatic metastasis of liver cancer cells.2003

    • Author(s)
      Kanetaka, K.
    • Journal Title

      J. Gastroenterol. Hepatol 18

      Pages: 1309-1314

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Unfavorable prognostic factors associated with high frequency of microsatellite instability and comparative genomic hybridization analysis in endometrial cancer.2003

    • Author(s)
      Hirasawa, A.
    • Journal Title

      Clin Cancer Res 15

      Pages: 5675-82

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] TERC identified as a probable target within the 3q26 amplicon that is detected frequently in non-small cell lung cancers.2003

    • Author(s)
      Yokoi, S.
    • Journal Title

      Clin Cancer Res 15

      Pages: 4705-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas.2003

    • Author(s)
      Okamoto, H.
    • Journal Title

      Hepatology 38

      Pages: 1242-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of ZASC1 encoding a Kruppel-like zinc finger protein as a novel target for 3q26 amplification in esophageal squamous cell carcinomas.2003

    • Author(s)
      Imoto, I.
    • Journal Title

      Cancer Res 63

      Pages: 5691-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Down-regulation of SKP2 induces apoptosis in lung-cancer cells.2003

    • Author(s)
      Yokoi, S.
    • Journal Title

      Cancer Sci 94

      Pages: 344-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association of 17q21-q24 Gain in Ovarian Clear Cell Adenocarcinomas with Poor Prognosis and Identification of PPM1D and APPBP2 as Likely Amplification Targets.2003

    • Author(s)
      Hirasawa, A.
    • Journal Title

      Clin Cancer Res 9

      Pages: 1995-2004

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] PPM1D is a potential target for 17q gain in neuroblastoma.2003

    • Author(s)
      Saito-Ohara, F.
    • Journal Title

      Cancer Res 63

      Pages: 1876-83

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cell culture in esophageal squamous cell carcinoma and the association with molecular markers.2003

    • Author(s)
      Shimada, Y.
    • Journal Title

      Clin Cancer Res 9

      Pages: 243-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Presenilin-dependent g-secretase activity mediates the intramembranous cleavage of CD44.2003

    • Author(s)
      Murakami, D.
    • Journal Title

      Oncogene 22

      Pages: 1511-1516

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Aurora-A and an interacting activator the LIM protein Ajuba are required for mitotic commitment in human cells.2003

    • Author(s)
      Hirota, T.
    • Journal Title

      Cell 114

      Pages: 585-598

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cells.2003

    • Author(s)
      Marumoto, T.
    • Journal Title

      J. Biol. Chem 278

      Pages: 51786-51795

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Aurora-A-dependent phosphorylation of CENP-A in prophase is essential for concentration of Aurora-B at inner centromeres and for kinetochore function.2003

    • Author(s)
      Kunitoku, N.
    • Journal Title

      Dev. Cell 5

      Pages: 853-864

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Monitoring minimal residual disease in leukemia using real-time quantitative polymerase chain reaction for Wilms tumor gene (WT1).2003

    • Author(s)
      Tamaki, H.
    • Journal Title

      Int J Hematol 78

      Pages: 349-56

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in primary thyroid cancer.2003

    • Author(s)
      Oji, Y.
    • Journal Title

      Cancer Sci 94

      Pages: 606-611

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in colorectal adenocarcinoma.2003

    • Author(s)
      Oji, Y.
    • Journal Title

      Cancer Sci 94

      Pages: 712-717

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in head and neck squamous cell carcinoma.2003

    • Author(s)
      Oji, Y.
    • Journal Title

      Cancer Sci 94

      Pages: 523-529

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] WT1 peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis.2003

    • Author(s)
      Oka, Y.
    • Journal Title

      Int J Hematol 78

      Pages: 56-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in human bone and soft-tissue sarcomas.2003

    • Author(s)
      Ueda, T.
    • Journal Title

      Cancer Sci 94

      Pages: 271-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia.2003

    • Author(s)
      Ogawa, H.
    • Journal Title

      Blood 101

      Pages: 1698-1704

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association between mitotic spindle checkpoint impairment and susceptibility to the induction of apoptosis by antimicrotubule agents in human lung cancers.2003

    • Author(s)
      Masuda, A.
    • Journal Title

      Am. J. Pathol 163

      Pages: 1106-1119

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase reduced folate carrier and thymidylate synthase mRNA expression in osteosarcoma.2003

    • Author(s)
      Sowers, R.
    • Journal Title

      Mol. Cancer Ther. 2

      Pages: 535-41

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Altered expression of the receptor and ligand in the TGF beta signaling pathway in diffusely infiltrating colon carcinoma.2003

    • Author(s)
      Nagayama, S.
    • Journal Title

      Anticancer Res 22

      Pages: 3545-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inserting chromosome 18 into pancreatic cancer cells switches them to a dormant metastatic phenotype.2003

    • Author(s)
      Lefter L. P.
    • Journal Title

      Clin. Cancer Res 9

      Pages: 5044-5052

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.2003

    • Author(s)
      Duda D. G.
    • Journal Title

      Oncogene 22

      Pages: 6857-6864

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer.2003

    • Author(s)
      Furukawa, T.
    • Journal Title

      Am. J. Pathol. 162

      Pages: 1807-1815

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Analysis of gene-expression profiles in testicular seminomas using a genome-wide cDNA microarray.2003

    • Author(s)
      Okada, K.
    • Journal Title

      Int J Oncol 23

      Pages: 1615-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular detection of von Hippel-Lindau gene mutations in urine and lymph node samples in patients with renal cell carcinoma : potential biomarkers for early diagnosis and postoperative metastatic status.2003

    • Author(s)
      Ashida, S.
    • Journal Title

      J Urol 169

      Pages: 2089-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9.2003

    • Author(s)
      Yoshida, K.
    • Journal Title

      EMBO J 22

      Pages: 1431-1441

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic polymorphism at the 5'regulatory region of MDR1 and its association with inter-individual variation of expression level in colon.2003

    • Author(s)
      Taniguchi, S.
    • Journal Title

      Mol Cancer Ther 12

      Pages: 1351-1359

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Frizzled 4 gene (FZD4) mutations in patients with familial exudative vitreoretinopathy with variable expressivity.2003

    • Author(s)
      Kondo, H.
    • Journal Title

      Br J Ophthalmol 87

      Pages: 1291-1295

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Single-stranded conformational polymorphism analysis using automated capillary array electrophoresis apparatus.2003

    • Author(s)
      Baba, S.
    • Journal Title

      Bio Techniques 34

      Pages: 746-750

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] SNP detection and allele frequency determination by SSCP.2003

    • Author(s)
      Tahira, T.
    • Journal Title

      Methods Mol Biol 212

      Pages: 37-46

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HLA haplotype is associated with diabetes among atomic bomb survivors.2003

    • Author(s)
      Hayashi, T.
    • Journal Title

      Hum. Immunol 64

      Pages: 910-916

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Isoliquiritigenin inhibits the growth of prostate cancer.2003

    • Author(s)
      Kanazawa, M.
    • Journal Title

      Eur. Urology 43

      Pages: 580-586

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] H-ras mutations at codon 61 or 13 in tumors initiated with a NO donor in mouse skin.2003

    • Author(s)
      Satomi, Y.
    • Journal Title

      Cancer Lett 196

      Pages: 17-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression profiling in ovarian clear cell carcinoma : identification of hepatocyte nuclear actor-1 β as a molecular marker and a possible molecular target for therapy of ovarian clear cell carcinoma.2003

    • Author(s)
      Tsuchiya, A.
    • Journal Title

      Am. J. Pathol 163

      Pages: 2503-2512

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice form Atherosclerosis.2003

    • Author(s)
      Yamauchi, T.
    • Journal Title

      J. Biol. Chem. 278

      Pages: 2461-2468

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Lymphoid enhancer factor 1 makes cells resistant to transforming growth factor β-induced repression of c-myc.2003

    • Author(s)
      Sasaki, T.
    • Journal Title

      Cancer Res. 63

      Pages: 801-806

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Effects of Donor Cell Type and Genotype on the Efficiency of Mouse Somatic Cell Cloning.2003

    • Author(s)
      Inoue, K.
    • Journal Title

      Biol Reprod. 69

      Pages: 1394-1400

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Long-Term Proliferation in Culture and Germline Transmission of Mouse Male Germline Stem Cells.2003

    • Author(s)
      Kanatsu-Shinohara, M.
    • Journal Title

      Biol Reprod. 69

      Pages: 612-616

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis.2003

    • Author(s)
      Chida, K.
    • Journal Title

      Cancer Res. 15

      Pages: 2404-2408

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Immunomic analysis of human sarcoma.2003

    • Author(s)
      Lee, S-Y.
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 100

      Pages: 2561-2656

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells : Therapeutic effect of a novel polyarginine-conjugated smac peptide.2003

    • Author(s)
      Yang, L.
    • Journal Title

      Cancer Res 63

      Pages: 831-837

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Single amino acid substitutions in the Tran membrane domains of breast cancer resistance protein (BCRP) alter cross resistance patterns in the transfectants.2003

    • Author(s)
      Miwa, M.
    • Journal Title

      Int. J. Cancer 107

      Pages: 757-767

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Natural product origins of Hsp90 inhibitors. Hsp90 Molecular Chaperon Inhibitors : Opportunities and Challenges.2003

    • Author(s)
      Uehara, Y.
    • Journal Title

      Current Cancer Drug Targets 3

      Pages: 319-324

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Translational and clinical studies of target based drugs.2003

    • Author(s)
      Saijo, N.
    • Journal Title

      Int. J. Clin. Oncol 8

      Pages: 187-192

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Clinical significance of CCR4 expression in adult T-cell leukemia/lymphoma : its close association with skin involvement and unfavorable outcome.2003

    • Author(s)
      Ishida, T.
    • Journal Title

      Clin. Cancer Res 9

      Pages: 3625-3634

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multiple primary cancer : an experience at the Cancer Institute Hospital with special reference to colorectal cancer.2003

    • Author(s)
      Ueno, M.
    • Journal Title

      Int. J. Clin. Oncol 8

      Pages: 162-167

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Elevation of circulating plasma cytokines in cancer patients with high plasma parathyroid hormone-related protein levels.2003

    • Author(s)
      Takahashi, S.
    • Journal Title

      Endocr.Relat.Cancer 10

      Pages: 403-407

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prediction of response to imatinib by cDNA microarray analysis.2003

    • Author(s)
      Ohno, R.
    • Journal Title

      Semin. Hematol 40(2 Suppl 2)

      Pages: 42-49

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Late skin and subcutaneous soft tissue changes after 10-gy boost for breast conserving therapy.2003

    • Author(s)
      Okumura S.
    • Journal Title

      Breast Cancer 10

      Pages: 129-133

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer.2003

    • Author(s)
      Fukuoka, M.
    • Journal Title

      J. Clin. Oncol 21

      Pages: 2237-2246

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Combined therapy with a new bisphosphonate minodronate (YM529) and chemotherapy for multiple organ metastases of small cell lung cancer cells in severe combined immunodeficient mice.2003

    • Author(s)
      Yano, S.
    • Journal Title

      Clin. Cancer Res 9

      Pages: 5380-5385

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A loss of function mutation in WISP3 derived from microsatellite unstable gastric carcinoma.2003

    • Author(s)
      Tanaka, S.
    • Journal Title

      Gastroenterology 125

      Pages: 1563-1564

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3.2002

    • Author(s)
      Sato, S., et al.
    • Journal Title

      J. Biol. Chem 277

      Pages: 39360-39367

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.2002

    • Author(s)
      Rokudai, S., et al.
    • Journal Title

      Mol. Cell. Biol 22

      Pages: 8695-8708

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53AIP1 regulates the mitochondrial apoptotic pathway.2002

    • Author(s)
      Matsuda, K., et al.
    • Journal Title

      Cancer Res 62

      Pages: 2883-2889

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Green tea : Cancer preventive beverage and/or drug.2002

    • Author(s)
      Fujiki, H., et al.
    • Journal Title

      Cancer Lett 188

      Pages: 9-13

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Target disruption of the mutant β -catenin gene in colon cancer cell line HCT116 : preservation of its malignant phenotype.2002

    • Author(s)
      Sekine, S., et al.
    • Journal Title

      Oncogene 21

      Pages: 5906-5911

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines.2002

    • Author(s)
      Dan, S., et al.
    • Journal Title

      Cancer Res 62

      Pages: 1139-1147

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] β-Hydroxyisovalerylshikonin is a novel and potent inhibitor of protein tyrosine kinases.2002

    • Author(s)
      Hashimoto, S., et al.
    • Journal Title

      Jpn J Cancer Res 93

      Pages: 944-951

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibition of DNA toopoisomerases I and/or I by pyrazolo[1,5-a]indole derivatives and their growth inhibitory acitivities.2002

    • Author(s)
      Umemura, K., et al.
    • Journal Title

      Molec Pharmacol 62

      Pages: 873-880

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prolonged Nuclear Retention of Activated Extracellular Signal-Regulated Kinase1/2 is Required for Hepatocyte Growth Factor-induced Cell Motility.2002

    • Author(s)
      Tanimura, S., et al.
    • Journal Title

      J. Biol. Chem 277

      Pages: 28256-28264

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.2002

    • Author(s)
      Furumai, R., et al.
    • Journal Title

      Cancer Res 62

      Pages: 4916-4921

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] ZD 1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase.2002

    • Author(s)
      Hirata, A., et al.
    • Journal Title

      Cancer Res 62

      Pages: 2554-2560

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] IFN-beta-mediated inhibition of tumor angiogenesis by the natural killer T cell ligand alpha-galactosylceramide.2002

    • Author(s)
      Hayakawa Y., et al.
    • Journal Title

      Blood 100

      Pages: 1728-1733

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MS-209 a quinoline-type reversal agent potentiates antitumor efficacy of docetaxel in multidrug-resistant solid tumor xenograft models.2002

    • Author(s)
      Naito, M., et al.
    • Journal Title

      Clin. Cancer Res. 8

      Pages: 582-588

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] C421A polymorphism in the human breast cancer resistant protein gene is associated with low expression of Q 141 K protein and low-level drug resistance.2002

    • Author(s)
      Imai, Y., et al.
    • Journal Title

      Mol Cancer Ther 1

      Pages: 611-616

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Versipelostatin a novel GRP78/Bip molecular chaperone down-regulator of microbial origin.2002

    • Author(s)
      Park, H-R., et al.
    • Journal Title

      Tetrahedron Lett 43

      Pages: 6941-6945

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nuclear localization of proteasomes participates in stress-inducible resistance of solid tumor cells to topoisomerase II-directed drugs.2002

    • Author(s)
      Ogiso, Y., et al.
    • Journal Title

      Cancer Res 62

      Pages: 5008-5012

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Link between the Tumor Suppressor APC and the Kinesin Superfamily of Proteins2002

    • Author(s)
      Jimbo T., et al.
    • Journal Title

      nature Cell Biol 4

      Pages: 323-327

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Superior mesenteric venous thrombosis associated with a familial missense mutation (Pro626Leu) in the SHBG-like domain of the protein S molecule.2002

    • Author(s)
      Kato M., et al.
    • Journal Title

      Int. J. Hematol 75

      Pages: 100-103

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nectin : an adhesion molecule involved in formation of synapses.2002

    • Author(s)
      Mizoguchi A., et al.
    • Journal Title

      J Cell Biol 156

      Pages: 555-565

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The interferon-alpha/beta system in antiviral responses : a multimodal machinery of gene regulation by the IRF family of transcription factors.2002

    • Author(s)
      Taniguchi T., et al.
    • Journal Title

      Curr Opin Immunol 14

      Pages: 111-116

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1 (PDK1).2002

    • Author(s)
      Fujita N., et al.
    • Journal Title

      J Biol Chem 277

      Pages: 10346-10353

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of link between the Tumor Suppressor APC and the Kinesin Superfamily of Proteins.2002

    • Author(s)
      Jimbo, T., et al.
    • Journal Title

      nature Cell Biol 4

      Pages: 323-327

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.2002

    • Author(s)
      Zembutsu, H., et al.
    • Journal Title

      Cancer Res 62

      Pages: 518-527

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MMP9 induction by Vascular Endpthelial Growth Factor Receptor-1 is involved in lung specific metastasis.2002

    • Author(s)
      Hiratsuka, S., et al.
    • Journal Title

      Cancer Cell 2

      Pages: 289-300

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP.2002

    • Author(s)
      Izutsu, K., et al.
    • Journal Title

      Oncogene 21

      Pages: 2695-2703

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MICAL a novel CasL interacting molecule associates with vimentin.2002

    • Author(s)
      Suzuki, T., et al.
    • Journal Title

      J. Biol. Chem 277

      Pages: 14933-14941

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] RANKL maintains bone homeostasis through c-Fos-dependent induction of IFN-β.2002

    • Author(s)
      Takayanagi, H., et al.
    • Journal Title

      Nature 416

      Pages: 744-749

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.2002

    • Author(s)
      Hanafusa, H., et al.
    • Journal Title

      nature Cell Biol 4

      Pages: 850-858

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Claudin-based tight junctions are crucial for the mammalian epidermal barrier : A lesson from claudin-1-deficient mice.2002

    • Author(s)
      Furuse, M., et al.
    • Journal Title

      J.Cell Biol 156

      Pages: 1099-1111

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes.2002

    • Author(s)
      Kikuchi, S., et al.
    • Journal Title

      Nat.Genet 31

      Pages: 320-325

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Trans-interactions of nectins induce formation of filopodia and lamellipodia through the respective activation of Cdc42 and Rac small G proteins.2002

    • Author(s)
      Kawakatsu, T., et al.
    • Journal Title

      J. Biol. Chem 277

      Pages: 50749-50755

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel mechabism of nuclear factor kB activation through the binding between inhibitor of nuclear factor-kappaBalpha and the processed NH2-terminal region of Mig-6.2002

    • Author(s)
      Tsunoda, T., et al.
    • Journal Title

      Cancer Res 62

      Pages: 5668-5671

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] for the Japan Marrow Donor Program The clinical significance of HLA allele compatibility in patients transplanted with marrow from a serologically HLA-A B and DR matched unrelated donor.2002

    • Author(s)
      Morishima, Y., et al.
    • Journal Title

      Blood 99

      Pages: 4200-4206

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons.2002

    • Author(s)
      Sugitani, Y., et al.
    • Journal Title

      Genes Dev 16

      Pages: 1760-1765

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Lack of acrosome formation in mice lacking a Golgi protein GOPC.2002

    • Author(s)
      Yao, R., et al.
    • Journal Title

      Proc Natl Acad Sci USA 99

      Pages: 11211-11216

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene.2002

    • Author(s)
      Hasegawa, S., et al.
    • Journal Title

      Proc Natl Acad Sci USA 99

      Pages: 297-302

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain.2002

    • Author(s)
      Mori, H., et al.
    • Journal Title

      EMBO J 21

      Pages: 3949-3959

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Two-step sandwich enzyme immunoassay, using monoclonal antibodies for detection of soluble and membrane-associated human membrane type 1-matrix metalloproteinase.2002

    • Author(s)
      Aoki, T., et al.
    • Journal Title

      J Immunoassay Immunochem 23

      Pages: 49-68

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin- Reed-Sternberg cells.2002

    • Author(s)
      Horie, K., et al.
    • Journal Title

      Oncogene 21

      Pages: 2493-2503

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death.2002

    • Author(s)
      Kim, JM., et al.
    • Journal Title

      EMBO J 21

      Pages: 2168-2179

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Enhanced skin carcinogenesis in cyclin D1-conditional transgenic mice : cyclin D1 alters keratinocyte response to calcium-induced terminal differentiation.2002

    • Author(s)
      Yamamoto, H., et al.
    • Journal Title

      Cancer Res 62

      Pages: 1641-1647

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells.2002

    • Author(s)
      Shonai, T., et al.
    • Journal Title

      Cell Death Differ 9

      Pages: 963-971

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta.2002

    • Author(s)
      Takekawa, M., et al.
    • Journal Title

      EMBO J 21

      Pages: 6473-6482

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Role of CCK-A receptor for pancreatic function in mice : a study in CCK-A receptor knockout mice.2002

    • Author(s)
      Takiguchi, S., et al.
    • Journal Title

      Pancreas 24

      Pages: 276-283

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] β-catenin mutations in sporadic fundic gland polyps.2002

    • Author(s)
      Sekine, S., et al.
    • Journal Title

      Virch Arch 440

      Pages: 381-386

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4 associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis.2002

    • Author(s)
      Saito, Y., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 99

      Pages: 10060-10065

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Clinicopathological significance of galectin-3 expression in ductal adenocarcinoma of the pancreas.2002

    • Author(s)
      Shimamura, T., et al.
    • Journal Title

      Clin. Cancer Res 8

      Pages: 2570-2575

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Craniopharyngiomas of admantinomatous type harbor β-catenin gene mutations.2002

    • Author(s)
      Sekine, S., et al.
    • Journal Title

      Am. J. Pathol 161

      Pages: 1997-2001

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of cIAP1 a target for 11q22 amplification correlates with resistance of cervical cancers to radiotherapy.2002

    • Author(s)
      Imoto, I., et al.
    • Journal Title

      Cancer Res 62

      Pages: 1079810-1079810

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Damaged epithelia regenerated by bone marrow-derived cells in the Human gastrointestinal tract.2002

    • Author(s)
      Okamoto, R., et al.
    • Journal Title

      Nat Med 8

      Pages: 1011-1017

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel target gene, SKP2 within the 5p13 amplicon that is frequently detected in small cell lung cancers.2002

    • Author(s)
      Yokoi, S., et al.
    • Journal Title

      Am J Pathol 161

      Pages: 207-216

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] TFDP1, CUL4A and CD16 identified as targets for amplification at 13q34 in hepatocellular carcinomas.2002

    • Author(s)
      Yasui, K., et al.
    • Journal Title

      Hepatology 35

      Pages: 1476-1484

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Causal relationship between the loss of RUNX3 expression and gastric cancer.2002

    • Author(s)
      Li, QL., et al.
    • Journal Title

      109

      Pages: 113-124

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Novel targets for the 18p11 3 amplification frequently observed in esophageal squamous cell carcinomas.2002

    • Author(s)
      Nakakuki, K., et al.
    • Journal Title

      Carcinogenesis 23

      Pages: 19-24

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers.2002

    • Author(s)
      Watanabe, T., et al.
    • Journal Title

      Jpn. J. Cancer Res 93

      Pages: 1114-1122

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Down-regulation of a novel gene, DRLM in human liver malignancy from 4q22 that encodes an NAP-like protein.2002

    • Author(s)
      Harada, H., et al.
    • Journal Title

      Gene 296

      Pages: 171-177

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Down-regulation in human cancers of DRHC a novel helicase-like gene from 17q25 1 that inhibit cell growth.2002

    • Author(s)
      Nagai, H., et al.
    • Journal Title

      Cancer Lett 10

      Pages: 41-47

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A^*2402-binding residues.2002

    • Author(s)
      Tsuboi, A., et al.
    • Journal Title

      Cancer Immunol Immunother 51

      Pages: 614-620

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers.2002

    • Author(s)
      Oji, Y., et al.
    • Journal Title

      Int J Cancer 100

      Pages: 297-303

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HLA class II haplotype and quantitation of the WT1 gene in Japanese patients with paroxysmal nocturnal hemaglobinuria (PNH).2002

    • Author(s)
      Shichishima, T., et al.
    • Journal Title

      Blood 100

      Pages: 22-28

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A Humoral immune responses against Wilms' tumor gene WT1 product in patients with hematopoietic malignancies.2002

    • Author(s)
      Elisseeva, O., et al.
    • Journal Title

      Blood 99

      Pages: 3272-3279

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of frequent G2 checkpoint impairment and a homozygous deletion of 14-3-3_at 17p13 3 in small cell lung cancers.2002

    • Author(s)
      Konishi, H., et al.
    • Journal Title

      Cancer Res 62

      Pages: 271-276

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers.2002

    • Author(s)
      Mizuno, K., et al.
    • Journal Title

      Oncogene 21

      Pages: 2328-2333

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] TLS-CHOP target gene DOL54 experssion in liposarcoimas and malignant fribrous histiocytomas.2002

    • Author(s)
      Domoto, H., et al.
    • Journal Title

      Pathol. Int 52

      Pages: 497-500

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.2002

    • Author(s)
      Nishimori, H., et al.
    • Journal Title

      Oncogene 21

      Pages: 2337065-2337065

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genome-wide analysis of gene expression in synovial sarcomas using a cDNA mircroarray.2002

    • Author(s)
      Nagayama, S., et al.
    • Journal Title

      Cancer Res 62

      Pages: 5859-5866

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutation analysis of the NFAT1 gene in chodrosarcomas and enchondromas.2002

    • Author(s)
      Aoyama, T., et al.
    • Journal Title

      Cancer Lett 186

      Pages: 49-57

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Morphological and biological heterogeneity of three tumorigenic cell lines derived from a single p53-/- osteoblast-like cell line MMC2.2002

    • Author(s)
      Murakami, H., et al.
    • Journal Title

      Cancer Lett 182

      Pages: 203-211

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel type of EWS-CHOP fusion gene in two cases of myxoid liposarcoma.2002

    • Author(s)
      Hosaka, T., et al.
    • Journal Title

      J. Mol.Diagn 4

      Pages: 164-171

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines.2002

    • Author(s)
      Lefter LP., et al.
    • Journal Title

      Genes Chromosomes Cancer 27

      Pages: 234-242

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutation analysis of the mel-18 gene that shows decreased expression in breast cancer cell lines.2002

    • Author(s)
      Matsuo, F., et al.
    • Journal Title

      Breast Cancer 9

      Pages: 33-38

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members.2002

    • Author(s)
      Morotomi-Yano, K., et al.
    • Journal Title

      J. Biol. Chem 277

      Pages: 836-842

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification and characterization of the human protein kinase-like gene NTKL : mitosis-specific centrosomal localization of an alternatively spliced isoform.2002

    • Author(s)
      Kato, M., et al.
    • Journal Title

      Genomics 79

      Pages: 760-767

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of SAPK/JNK Signaling by Protein Kinase C in Response to DNA Damage.2002

    • Author(s)
      Yoshida, K., et al.
    • Journal Title

      J. Biol. Chem 277

      Pages: 48372-48378

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutational analysis of the PTEN gene localized at chromosome 10q23 in Thai patients with gliomas.2002

    • Author(s)
      Buntup, D., et al.
    • Journal Title

      Science 28

      Pages: 417-422

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A software for machine-independent quantitative interpretation of SSCP in capillary array electrophoresis (QUISCA).2002

    • Author(s)
      Higasa, K., et al.
    • Journal Title

      BioTechniques 33

      Pages: 1342-1348

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Hemi-stranded SSCP analysis of single-nucleotide polymorphisms in short sequence-tagged sites.2002

    • Author(s)
      Kukita, Y., et al.
    • Journal Title

      BioTechniques 33

      Pages: 1118-1121

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multicolor post-PCR labeling of DNA fragments with fluorescent dideoxynucleotides.2002

    • Author(s)
      Kukita, Y., et al.
    • Journal Title

      BioTechniques 33

      Pages: 502-506

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A single-strand conformation polymorphism method for the large-scale analysis of mutations/polymorphisms using capillary-array electrophoresis.2002

    • Author(s)
      Kukita, Y., et al.
    • Journal Title

      Electrophoresis 23

      Pages: 2259-2266

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular cloning and the characterization of Caspase-8L : A novel isoform of caspase 8 that behaves as an inhibitor of the caspase cascade.2002

    • Author(s)
      Himeji, D., et al.
    • Journal Title

      Blood 99

      Pages: 4070-4078

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multiplexed analysis of post-PCR fluorescence-labeled microsatellite alleles and statistical evaluation of their imbalance in brain tumors.2002

    • Author(s)
      Yoshimoto, K., et al.
    • Journal Title

      Jpn J Cancer Res 93

      Pages: 284-290

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of the biological function of a transcription factor c-myc intron binding protein 1 (MIBP1).2002

    • Author(s)
      Fukuda, S., et al.
    • Journal Title

      J. Biochemistry 131

      Pages: 349-357

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ordered catenation of sequence-tagged sites and multiplexed SNP-genotyping by sequencing.2002

    • Author(s)
      Higasa, K., et al.
    • Journal Title

      Nucl. Acids Res 30

      Pages: 1-14

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Studies on cancer chemoprevention by traditional folk medicines XXIV Inhibitory effect of a coumarin derivative, 7-isopentenyloxycoumarin against tumor-promotion.2002

    • Author(s)
      Baba, M., et al.
    • Journal Title

      Biol. Pharm. Bull 25

      Pages: 244-246

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Isoliquiritigenin suppresses pulumonary metastasis of mouse renal cell carcinoma.2002

    • Author(s)
      Yamazaki, S., et al.
    • Journal Title

      Cancer Lett 183

      Pages: 23-30

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species.2002

    • Author(s)
      Masuda, M., et al.
    • Journal Title

      Chemico-Biol. Interactions

      Pages: 187-197

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Site-directed integration of the cre gene mediated by Cre recombinase using a combination of mutant lox sites.2002

    • Author(s)
      Araki, K., et al.
    • Journal Title

      Nucleic Acid Res. 30

      Pages: 1-8

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Increased insulin sensitivity despite lipodystrophy in heterozygous CBP deficient mice.2002

    • Author(s)
      Yamauchi, T., et al.
    • Journal Title

      nature Genetics 30

      Pages: 221-226

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Maturation of mouse fetal germ cells in vitro.2002

    • Author(s)
      Obata, Y., et al.
    • Journal Title

      nature 418

      Pages: 497-498

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Faithful expression of imprinted genes in cloned mice.2002

    • Author(s)
      Inoue, K., et al.
    • Journal Title

      Science 295

      Pages: 297-297

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Early death of mice cloned from somatic cells.2002

    • Author(s)
      Ogonuki, N., et al.
    • Journal Title

      Nat. Genet. 30

      Pages: 253-254

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nekll a new member of the NIMA family of kinases involved in DNA replication and genotoxic stress responses.2002

    • Author(s)
      Noguchi, K., et al.
    • Journal Title

      J. Biol. Chem 277

      Pages: 39655-39665

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Antitumor activity of the selective epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TK1) Iressa(r) (ZD1839) in an EGFR-expressing multidrug resistant cell line in vitro and in vivo.2002

    • Author(s)
      Naruse, I., et al.
    • Journal Title

      Int. J. Cancer 98

      Pages: 310-315

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain.2002

    • Author(s)
      Kiyoki, H., et al.
    • Journal Title

      Oncogene 21

      Pages: 2555-2563

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel adenine nucleotide translocase inhibitor, MT-21 induces cytochromec release by a mitochondrial permeability transition-independent mechanism.2002

    • Author(s)
      Machida, K., et al.
    • Journal Title

      J. Biol. Chem 277

      Pages: 31243-31248

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Predictors of successful hepatic resection : prognostic usefulness of hepatic asialoglycoprotein receptor analysis.2002

    • Author(s)
      Kokudo, N., et al.
    • Journal Title

      World J. Surg 26

      Pages: 1342-1347

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Leukemic cell-surface CD13/aminopeptidase N and resistance to apoptosis mediated by endothelial cells.2002

    • Author(s)
      Mishima, Y., et al.
    • Journal Title

      J. Natl. Cancer Inst 94

      Pages: 1020-1028

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.2002

    • Author(s)
      Kaneta, Y., et al.
    • Journal Title

      Jpn. J. Cancer Res 93

      Pages: 849-856

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Adjuvant radiation therapy following mastectomy for breast cancer.2002

    • Author(s)
      Hiraoka, M., et al.
    • Journal Title

      Breast Cancer 9

      Pages: 190-195

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer : results of the Japan Clinical Oncology Group Study 9104.2002

    • Author(s)
      Takada, M., et al.
    • Journal Title

      J. Clin. Oncol 20

      Pages: 3054-3060

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activity of a new vascular targeting agent, ZD6126 in pulmonary metastases by human lung adenocarcinoma in nude mice.2002

    • Author(s)
      Goto, H., et al.
    • Journal Title

      Cancer Res. 62

      Pages: 3711-3715

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Detection of disseminated cancer cells in bone marrow of gastric cancer using real time quantitative reverse transcriptase polymerase chain reaction.2002

    • Author(s)
      Oki, E., et al.
    • Journal Title

      Cancer Let 188

      Pages: 191-198

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Interference with PDK1-Akt survival signaling pathway by UCN-01(7-hydroxystaurosporine).2002

    • Author(s)
      Sato, S., et al.
    • Journal Title

      Oncogene 21

      Pages: 1727-1738

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization.2002

    • Author(s)
      Kage, K., et al.
    • Journal Title

      Int. J. Cancer 97

      Pages: 626-630

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Biosynthesis of hibarimicins I 13C-Labeling Experiments.2002

    • Author(s)
      Hori, H., et al.
    • Journal Title

      J. Antibiot 55

      Pages: 46-52

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3.2002

    • Author(s)
      Sato, S.
    • Journal Title

      J. Biol. Chem 277

      Pages: 39360-39367

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.2002

    • Author(s)
      Rokudai, S.
    • Journal Title

      Mol.Cell.Biol 22

      Pages: 8695-8708

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53AIP1 regulates the mitochondrial apoptotic pathway.2002

    • Author(s)
      Matsuda, K.
    • Journal Title

      Cancer Res 62

      Pages: 2883-2889

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Green tea : Cancer preventive beverage and/or drug.2002

    • Author(s)
      Fujiki, H.
    • Journal Title

      Cancer Lett 188

      Pages: 9-13

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Target disruption of the mutant β-catenin gene in colon cancer cell line HCT116 : preservation of its malignant phenotype.2002

    • Author(s)
      Sekine, S.
    • Journal Title

      Oncogene 21

      Pages: 5906-5911

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] An integrated database of chemosensitivity to 55 anticancer drugs and gene expression profiles of 39 human cancer cell lines.2002

    • Author(s)
      Dan, S.
    • Journal Title

      Cancer Res 62

      Pages: 1139-1147

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] β-Hydroxyisovalerylshikonin is a novel and potent inhibitor of protein tyrosine kinases.2002

    • Author(s)
      Hashimoto, S.
    • Journal Title

      Jpn J Cancer Res 93

      Pages: 944-951

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibition of DNA toopoisomerases I and/or I by pyrazolo [1,5-a] indole derivatives and their growth inhibitory activities.2002

    • Author(s)
      Umemura, K.
    • Journal Title

      Molec Pharmacol 62

      Pages: 873-880

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prolonged Nuclear Retention of Activated Extracellular Signal-Regulated Kinase 1/2 is Required for Hepatocyte Growth Factor-induced Cell Motility.2002

    • Author(s)
      Tanimura, S.
    • Journal Title

      J. Biol. Chem 277

      Pages: 28256-28264

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases.2002

    • Author(s)
      Furumai, R.
    • Journal Title

      Cancer Res 62

      Pages: 4916-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] ZD1839 (Iressa) induces antiangiogenic effects through inhibition of epidermal growth factor receptor tyrosine kinase.2002

    • Author(s)
      Hirata, A.
    • Journal Title

      Cancer Res 62

      Pages: 2554-2560

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] IFN-beta-mediated inhibition of tumor angiogenesis by the natural killer T cell ligand alpha-galactosylceramide.2002

    • Author(s)
      Hayakawa Y.
    • Journal Title

      Blood 100

      Pages: 1728-1733

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MS-209 a quinoline-type reversal agent potentiates antitumor efficacy of docetaxel in multidrug-resistant solid tumor xenograft models.2002

    • Author(s)
      Naito, M.
    • Journal Title

      Clin. Cancer Res. 8

      Pages: 582-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] C42 1A polymorphism in the human breast cancer resistant protein gene is associated with low expression of Q141K protein and low-level drug resistance.2002

    • Author(s)
      Imai, Y.
    • Journal Title

      Mol Cancer Ther 1

      Pages: 611-616

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Versipelostatin a novel GRP78/Bip molecular chaperone down-regulator of microbial origin.2002

    • Author(s)
      Park, H.-R.
    • Journal Title

      Tetrahedron Lett 43

      Pages: 6941-6945

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nuclear localization of proteasomes participates in stress-inducible resistance of solid tumor cells to topoisomerase II-directed drugs.2002

    • Author(s)
      Ogiso, Y.
    • Journal Title

      Cancer Res 62

      Pages: 5008-5012

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Link between the Tumor Suppressor APC and the Kinesin Superfamily of Proteins.2002

    • Author(s)
      T.Jimbo
    • Journal Title

      nature Cell Biol 4

      Pages: 323-327

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Superior mesenteric venous thrombosis associated with a familial missense mutation (Pro626Leu) in the SHBG-like domain of the protein S molecule.2002

    • Author(s)
      Kato M.
    • Journal Title

      Int. J. Hematol 75

      Pages: 100-103

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nectin : an adhesion molecule involved in formation of synapses.2002

    • Author(s)
      Mizoguchi, A.
    • Journal Title

      J Cell Biol 156

      Pages: 555-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The interferon-alpha/beta system in antiviral responses : a multimodal machinery of gene regulation by the IRF family of transcription factors.2002

    • Author(s)
      Taniguchi, T.
    • Journal Title

      Curr Opin Immunol 14

      Pages: 111-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1 (PDK1).2002

    • Author(s)
      Fujita, N.
    • Journal Title

      J Biol Chem 277

      Pages: 10346-10353

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of link between the Tumor Suppressor APC and the Kinesin Superfamily of Proteins.2002

    • Author(s)
      Jimbo, T.
    • Journal Title

      nature Cell Biol 4

      Pages: 323-327

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs.2002

    • Author(s)
      Zembutsu, H.
    • Journal Title

      Cancer Res 62

      Pages: 518-527

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MMP9 induction by Vascular Endothelial Growth Factor Receptor-1 is involved in lung specific metastasis.2002

    • Author(s)
      Hiratsuka, S.
    • Journal Title

      Cancer Cell 2

      Pages: 289-300

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtB P.2002

    • Author(s)
      Izutsu, K.
    • Journal Title

      Oncogene 21-17

      Pages: 2695-2703

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MICAL a novel CasL interacting molecule associates with vimentin.2002

    • Author(s)
      Suzuki, T.
    • Journal Title

      J. Biol. Chem 277-17

      Pages: 14933-14941

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] RANKL maintains bone homeostasis through c-Fos-dependent induction of IFN-β.2002

    • Author(s)
      Takayanagi, H
    • Journal Title

      Nature 416

      Pages: 744-749

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signaling pathway.2002

    • Author(s)
      Hanafusa, H
    • Journal Title

      nature Cell Biol 4

      Pages: 850-858

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Claudin-based tight junctions are crucial for the mammalian epidermal barrier : A lesson from claudin-1-deficient mice.2002

    • Author(s)
      Furuse, M
    • Journal Title

      J. Cell Biol 156-6

      Pages: 1099-1111

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes.2002

    • Author(s)
      Kikuchi, S
    • Journal Title

      Nat. Genet 31

      Pages: 320-325

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Trans-interactions of nectins induce formation of filopodia and lamellipodia through the respective activation of Cdc42 and Rac small G proteins.2002

    • Author(s)
      Kawakatsu, T
    • Journal Title

      J. Biol. Chem 277-52

      Pages: 50749-50755

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel mechanism of nuclear factor kB activation through the binding between inhibitor of nuclear factor-kappaB alpha and the processed NH2-terminal region of Mig-6.2002

    • Author(s)
      Tsunoda, T
    • Journal Title

      Cancer Res 62

      Pages: 5668-71

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] for the Japan Marrow Donor Program. The clinical significance of HLA allele compatibility in patients transplanted with marrow from a serologically HLA-A B and DR matched unrelated donor.2002

    • Author(s)
      Morishima, T.
    • Journal Title

      Blood 99

      Pages: 4200-4206

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons.2002

    • Author(s)
      Sugitani, Y
    • Journal Title

      Genes Dev 16

      Pages: 1760-1765

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Lack of acrosome formation in mice lacking a Golgi protein GOPC.2002

    • Author(s)
      Yao, R
    • Journal Title

      Proc Natl Acad Sci USA 99

      Pages: 11211-11216

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene.2002

    • Author(s)
      Hasegawa, S
    • Journal Title

      Proc Natl Acad Sci USA 99

      Pages: 297-302

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain.2002

    • Author(s)
      Mori, H
    • Journal Title

      EMBO J 21

      Pages: 3949-3959

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Two-step sandwich enzyme immunoassay using monoclonal antibodies for detection of soluble and membrane-associated human membrane type 1-matrix metalloproteinase.2002

    • Author(s)
      Aoki, T
    • Journal Title

      J Immunoassay Immunochem 23

      Pages: 49-68

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells.2002

    • Author(s)
      Horie, R.
    • Journal Title

      Oncogene 21

      Pages: 2493-2503

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death.2002

    • Author(s)
      Kim, J.M.
    • Journal Title

      EMBO J 21

      Pages: 2168-2179

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Enhanced skin carcinogenesis in cyclin D1-conditional transgenic mice : cyclin D1 alters keratinocyte response to calcium-induced terminal differentiation.2002

    • Author(s)
      Yamamoto, H.
    • Journal Title

      Cancer Res 62

      Pages: 1641-1647

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells.2002

    • Author(s)
      Shonai, T.
    • Journal Title

      Cell Death Differ 9

      Pages: 963-971

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta.2002

    • Author(s)
      Takekawa, M.
    • Journal Title

      EMBO J 21

      Pages: 6473-6482

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Role of CCK-A receptor for pancreatic function in mice : a study in CCK-A receptor knockout mice.2002

    • Author(s)
      Takiguchi, S.
    • Journal Title

      Pancreas 24

      Pages: 276-283

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] β-catenin mutations in sporadic fundic gland polyps.2002

    • Author(s)
      Sekine, S.
    • Journal Title

      Virch Arch 440

      Pages: 381-386

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4 associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis.2002

    • Author(s)
      Saito, Y.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 99

      Pages: 10060-10065

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Clinicopathological significance of galectin-3 expression in ductal adenocarcinoma of the pancreas.2002

    • Author(s)
      Shimamura, T.
    • Journal Title

      Clin. Cancer Res 8

      Pages: 2570-2575

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Craniopharyngiomas of admantinomatous type harbor β-catenin gene mutations.2002

    • Author(s)
      Sekine, S.
    • Journal Title

      Am. J. Pathol 161

      Pages: 1997-2001

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of cIAP1 a target for 11q22 amplification correlates with resistance of cervical cancers to radiotherapy.2002

    • Author(s)
      Imoto, I.
    • Journal Title

      Cancer Res 62

      Pages: 4860-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Damaged epithelia regenerated by bone marrow-derived cells in the human gastrointestinal tract.2002

    • Author(s)
      Okamoto, R.
    • Journal Title

      Nat Med 8

      Pages: 1011-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel target gene, SKP2 within the 5p13 amplicon that is frequently detected in small cell lung cancers.2002

    • Author(s)
      Yokoi, S.
    • Journal Title

      Am J Pathol 161

      Pages: 207-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] TFDP1, CUL4A and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas.2002

    • Author(s)
      Yasui, K.
    • Journal Title

      Hepatology 35

      Pages: 1476-84

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Causal relationship between the loss of RUNX3 expression and gastric cancer.2002

    • Author(s)
      Li, Q.L.
    • Journal Title

      Cell 109

      Pages: 113-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Novel targets for the 18p 11.3 amplification frequently observed in esophageal squamous cell carcinomas.2002

    • Author(s)
      Nakakuki, K.
    • Journal Title

      Carcinogenesis 23

      Pages: 19-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Differentially regulated genes as putative targets of amplifications at 20q in ovarian cancers.2002

    • Author(s)
      Watanabe, T.
    • Journal Title

      Jpn. J. Cancer Res 93

      Pages: 1114-1122

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Down-regulation of a novel gene, DRLM in human liver malignancy from 4q22 that encodes an NAP-like protein.2002

    • Author(s)
      Harada, H.
    • Journal Title

      Gene 296

      Pages: 171-177

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Down-regulation in human cancers of DRHC a novel helicase-like gene from 17q25.1 that inhibit cell growth.2002

    • Author(s)
      Nagai, H.
    • Journal Title

      Cancer Lett 10

      Pages: 41-47

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Enhanced induction of human WT1-specific cytotoxic T lymphocytes with a 9-mer WT1 peptide modified at HLA-A^★2402-binding residues.2002

    • Author(s)
      Tsuboi, A.
    • Journal Title

      Cancer Immunol Immunother 51

      Pages: 614-620

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers.2002

    • Author(s)
      Oji, Y.
    • Journal Title

      Int J Cancer 100

      Pages: 297-303

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] HLA class II haplotype and quantitation of the WT1 gene in Japanese patients with paroxysmal nocturnal hemaglobinuria (PNH).2002

    • Author(s)
      Shichishima, T.
    • Journal Title

      Blood 100

      Pages: 22-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Humoral immune responses against Wilms' tumor gene WT1 product in patients with hematopoietic malignancies.2002

    • Author(s)
      Elisseeva, O.A.
    • Journal Title

      Blood 99

      Pages: 3272-3279

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of frequent G2 checkpoint impairment and a homozygous deletion of 14-3-3_at 17p13.3 in small cell lung cancers.2002

    • Author(s)
      Konishi, H.
    • Journal Title

      Cancer Res 62

      Pages: 271-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers.2002

    • Author(s)
      Mizuno, K.
    • Journal Title

      Oncogene 21

      Pages: 2328-2333

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] TLS-CHOP target gene DOL54 expression in liposarcoimas and malignant fribrous histiocytomas.2002

    • Author(s)
      Domoto, H.
    • Journal Title

      Pathol. Int 52

      Pages: 497-500

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.2002

    • Author(s)
      Nishimori, H.
    • Journal Title

      Oncogene 21

      Pages: 8302-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray.2002

    • Author(s)
      Nagayama, S.
    • Journal Title

      Cancer Res 62

      Pages: 5859-66

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutation analysis of the NFAT1 gene in chodrosarcomas and enchondromas.2002

    • Author(s)
      Aoyama, T.
    • Journal Title

      Cancer Lett 186

      Pages: 49-57

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Morphological and biological heterogeneity of three tumorigenic cell lines derived from a single p53-/-osteoblast-like cell line MMC2.2002

    • Author(s)
      Murakami, H.
    • Journal Title

      Cancer Lett 182

      Pages: 203-11

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel type of EWS-CHOP fusion gene in two cases of myxoid liposarcoma.2002

    • Author(s)
      Hosaka, T.
    • Journal Title

      J. Mol. Diagn 4

      Pages: 164-71

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines.2002

    • Author(s)
      Lefter L. P.
    • Journal Title

      Genes Chromosomes Cancer 27

      Pages: 234-242

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutation analysis of the mel-18 gene that shows decreased expression in breast cancer cell lines.2002

    • Author(s)
      Matsuo, F.
    • Journal Title

      Breast Cancer 9

      Pages: 33-38

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members.2002

    • Author(s)
      Morotomi-Yano, K.
    • Journal Title

      J. Biol. Chem 277

      Pages: 836-842

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification and characterization of the human protein kinase-like gene NTKL : mitosis-specific centrosomal localization of an alternatively spliced isoform.2002

    • Author(s)
      Kato, M.
    • Journal Title

      Genomics 79

      Pages: 760-767

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of SAPK/JNK Signaling by Protein Kinase C in Response to DNA Damage.2002

    • Author(s)
      Yoshida, K.
    • Journal Title

      J. Biol. Chem 277

      Pages: 48372-48378

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutational analysis of the PTEN gene localized at chromosome 10q23 in Thai patients with gliomas.2002

    • Author(s)
      Buntup, D.
    • Journal Title

      Science Asia 28

      Pages: 417-422

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A software for machine-independent quantitative interpretation of SSCP in capillary array electrophoresis (QUISCA).2002

    • Author(s)
      Higasa, K.
    • Journal Title

      BioTechniques 33

      Pages: 1342-1348

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Hemi-stranded SSCP analysis of single-nucleotide polymorphisms in short sequence-tagged sites.2002

    • Author(s)
      Kukita, Y.
    • Journal Title

      BioTechniques 33

      Pages: 1118-1121

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multicolor post-PCR labeling of DNA fragments with fluorescent dideoxynucleotides.2002

    • Author(s)
      Kukita, Y.
    • Journal Title

      BioTechniques 33

      Pages: 502-506

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A single-strand conformation polymorphism method for the large-scale analysis of mutations/polymorphisms using capillary-array electrophoresis.2002

    • Author(s)
      Kukita, Y.
    • Journal Title

      Electrophoresis 23

      Pages: 2259-2266

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Molecular cloning and the characterization of Caspase-8L : A novel isoform of caspase 8 that behaves as an inhibitor of the caspase cascade.2002

    • Author(s)
      Himeji, D.
    • Journal Title

      Blood 99

      Pages: 4070-4078

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multiplexed analysis of post-PCR fluorescence-labeled microsatellite alleles and statistical evaluation of their imbalance in brain tumors.2002

    • Author(s)
      Yoshimoto, K.
    • Journal Title

      Jpn J Cancer Res 93

      Pages: 284-290

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of the biological function of a transcription factor c-myc intron binding protein 1 (MIBP1).2002

    • Author(s)
      Fukuda, S.
    • Journal Title

      J. Biochemistry 131

      Pages: 349-357

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Ordered catenation of sequence-tagged sites and multiplexed SNP-genotyping by sequencing.2002

    • Author(s)
      Higasa, K.
    • Journal Title

      Nucl. Acids Res 30,e11

      Pages: 1-14

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Studies on cancer chemoprevention by traditional folk medicines XXIV. Inhibitory effect of a coumarin derivative, 7-isopentenyloxycoumarin against tumor-promotion.2002

    • Author(s)
      Baba, M.
    • Journal Title

      Biol. Pharm. Bull 25

      Pages: 244-246

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Isoliquiritigenin suppresses pulumonary metastasis of mouse renal cell carcinoma.2002

    • Author(s)
      Yamazaki, S.
    • Journal Title

      Cancer Lett 183

      Pages: 23-30

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species.2002

    • Author(s)
      Masuda, M.
    • Journal Title

      Chemico-Biol. Interactions 139

      Pages: 187-197

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Site-directed integration of the cre gene mediated by Cre recombinase using a combination of mutant lox sites.2002

    • Author(s)
      Araki, K.
    • Journal Title

      Nucleic Acid Res. 30 e103

      Pages: 1-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Increased insulin sensitivity despite lipodystrophy in heterozygous CBP deficient mice.2002

    • Author(s)
      Yamauchi, T.
    • Journal Title

      nature Genetics 30

      Pages: 221-226

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Maturation of mouse fetal germ cells in vitro.2002

    • Author(s)
      Obata, Y.
    • Journal Title

      nature 418

      Pages: 497-498

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Faithful expression of imprinted genes in cloned mice.2002

    • Author(s)
      Inoue, K.
    • Journal Title

      Science 295

      Pages: 297-297

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nek 11 a new member of the NIMA family of kinases involved in DNA replication and genotoxic stress responses.2002

    • Author(s)
      Noguchi, K.
    • Journal Title

      J. Biol. Chem 277

      Pages: 39655-39665

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Antitumor activity of the selective epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TK1) Iressa (r) (ZD1839) in an EGFR-expressing multidrug resistant cell line in vitro and in vivo.2002

    • Author(s)
      Naruse, I.
    • Journal Title

      Int. J. Cancer 98

      Pages: 310-315

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain.2002

    • Author(s)
      Kiyoki, H.
    • Journal Title

      Oncogene 21

      Pages: 2555-2563

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel adenine nucleotide translocase inhibitor, MT-21 induces cytochrome c release by a mitochondrial permeability transition-independent mechanism.2002

    • Author(s)
      Machida, K.
    • Journal Title

      J. Biol. Chem 277

      Pages: 31243-31248

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Predictors of successful hepatic resection : prognostic usefulness of hepatic asialoglycoprotein receptor analysis.2002

    • Author(s)
      Kokudo, N.
    • Journal Title

      World J. Surg 26

      Pages: 1342-1347

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Leukemic cell-surface CD13/aminopeptidase N and resistance to apoptosis mediated by endothelial cells.2002

    • Author(s)
      Mishima, Y.
    • Journal Title

      J. Natl. Cancer Inst 94

      Pages: 1020-1028

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Prediction of sensitivity to STI571 among chronic myeloid leukemia patients by genome-wide cDNA microarray analysis.2002

    • Author(s)
      Kaneta, Y.
    • Journal Title

      Jpn. J. Cancer Res 93

      Pages: 849-856

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Adjuvant radiation therapy following mastectomy for breast cancer.2002

    • Author(s)
      Hiraoka, M.
    • Journal Title

      Breast Cancer 9

      Pages: 190-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer : results of the Japan Clinical Oncology Group Study 9104.2002

    • Author(s)
      Takada, M.
    • Journal Title

      J. Clin. Oncol 20

      Pages: 3054-3060

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activity of a new vascular targeting agent, ZD6126 in pulmonary metastases by human lung adenocarcinoma in nude mice.2002

    • Author(s)
      Goto, H.
    • Journal Title

      Cancer Res. 62

      Pages: 3711-3715

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Detection of disseminated cancer cells in bone marrow of gastric cancer using real time quantitative reverse transcriptase polymerase chain reaction.2002

    • Author(s)
      Oki, E.
    • Journal Title

      Cancer Let 188

      Pages: 191-198

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).2002

    • Author(s)
      Sato, S.
    • Journal Title

      Oncogene 21

      Pages: 1727-1738

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization.2002

    • Author(s)
      Kage, K.
    • Journal Title

      Int. J. Cancer 97

      Pages: 626-630

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Biosynthesis of hibarimicins. I. 13C-Labeling Experiments.2002

    • Author(s)
      Hori, H.
    • Journal Title

      J. Antibiotics 55

      Pages: 46-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] BAG-1M an isoform of Bcl-2-interacting protein BAG-1 enhances gene expression driven by CMV promoter.2001

    • Author(s)
      Tahakashi, N., et al.
    • Journal Title

      Biochem Biophys Res Commun 286

      Pages: 807-814

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Blockade of the extracellular signal-regulated kinase pathway induces marked G1 cell cycle arrest and apoptosis in tumor cells in which the pathway is constitutively activated : Up-regulation of p27Kip1.2001

    • Author(s)
      Hoshino, R., et al.
    • Journal Title

      J Biol Chem 276

      Pages: 2686-2692

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin.2001

    • Author(s)
      Furumai, R., et al.
    • Journal Title

      Proc Natl Acad Sci USA 98

      Pages: 87-92

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cyclic Hydroxamic-acid-containing Peptide 31 a potent synthetic histone deacetylase inhibitor with antitumor activity.2001

    • Author(s)
      Komatsu, Y., et al.
    • Journal Title

      Cancer Res 61

      Pages: 4459-4466

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Interferon gamma-dependent induction of thymidine phosphorylase/platelet-derived endothelial growth factor through gamma-activated sequence-like element in human macrophages.2001

    • Author(s)
      Goto, H., et al.
    • Journal Title

      Cancer Res 61

      Pages: 469-473

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Regulation of activator protein-1 activity in the mediastinal lymph node metastasis of lung cancer.2001

    • Author(s)
      Ichiki K., et al.
    • Journal Title

      Clin. Exp. Metastasis 18

      Pages: 539-545

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent-induced apoptosis.2001

    • Author(s)
      Mashima, T., et al.
    • Journal Title

      J Cell Physiol 188

      Pages: 352-358

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Telomestatin a novel telomerase inhibitor from Streptomyces anulatus.2001

    • Author(s)
      Shin-ya, K., et al.
    • Journal Title

      J. Am. Chem. Soc 123

      Pages: 1262-1263

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] In vitro reconstitution of the end replication problem.2001

    • Author(s)
      Ohki R., et al.
    • Journal Title

      Mol Cell Biol 21

      Pages: 5753-5766

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration.2001

    • Author(s)
      Fukui Y., et al.
    • Journal Title

      Nature 412

      Pages: 826-831

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells.2001

    • Author(s)
      Takahashi T., et al.
    • Journal Title

      EMBO J 20

      Pages: 2768-2778

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multifunctional strands in tight junctions.2001

    • Author(s)
      Tsukita S., et al.
    • Journal Title

      Nat Rev Mol Cell 2

      Pages: 285-293

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53DINP1 a p53-inducible gene regulates p53-dependent apoptosis.2001

    • Author(s)
      Okamura S., et al.
    • Journal Title

      Mol Cell 8

      Pages: 85-94

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase.2001

    • Author(s)
      Toyoshima-Morimoto F., et al.
    • Journal Title

      Nature 410

      Pages: 215-220

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Related Articles : Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.2001

    • Author(s)
      Shimizu K., et al.
    • Journal Title

      EMBO J 21

      Pages: 294-302

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a PDZ domain containing golgi protein GOPC as an interaction partner of frizzled.2001

    • Author(s)
      Yao, R., et al.
    • Journal Title

      Biochem Biophys Res Commun 286

      Pages: 771-778

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration.2001

    • Author(s)
      Kajita, M., et al.
    • Journal Title

      J Cell Biol 153

      Pages: 893-904

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.2001

    • Author(s)
      Itoh, Y., et al.
    • Journal Title

      EMBO J 20

      Pages: 4782-4793

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cytoplasmic tail dependent internalization of membrane-type 1 matrix metalloproteinase (MT1-MMP) is important for its invasion-promoting activity.2001

    • Author(s)
      Uekita, T., et al.
    • Journal Title

      J Cell Biol 155

      Pages: 1345-1356

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue.2001

    • Author(s)
      Haruta, M., et al.
    • Journal Title

      Nat Neurosci 4

      Pages: 1163-1164

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Glia-synapse Interaction through Ca2+-permeable AMPA receptors in Bergmann glia.2001

    • Author(s)
      Iino, M., et al.
    • Journal Title

      Science 292

      Pages: 926-929

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Efficient gene activation in cultured mammalian cells mediated by FLP recombinase-expressing recombinant adenovirus.2001

    • Author(s)
      Nakano, M., et al.
    • Journal Title

      Nucleic Acids Res 29

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Adenovirus-mediated transfection of Caspase-8 augments anoikis and inhibits peritoneal dissemination of human gastric carcinoma cells.2001

    • Author(s)
      Nishimura, S., et al.
    • Journal Title

      Cancer Res 61

      Pages: 7009-7014

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability.2001

    • Author(s)
      Yamamoto, H., et al.
    • Journal Title

      Cancer Res 61

      Pages: 3139-3144

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Conversion of Zonula Occludentes from tight to leaky strand type by introducing claudin-2 into MDCK I cells.2001

    • Author(s)
      Furuse, M., et al.
    • Journal Title

      J Cell Biol 153

      Pages: 263-272

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Junctional adhesion molecule (JAM) binds to PAR-3 : a possible mechanism for the recruitment of PAR-3 to tight junctions.2001

    • Author(s)
      Itoh, M., et al.
    • Journal Title

      J Cell Biol 154

      Pages: 491-497

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in human pancreatic adeno-carcinomas : Clinicopathological and prognostic significance of matrilysin expression.2001

    • Author(s)
      Yamamoto, H., et al.
    • Journal Title

      J Clin Oncol 19

      Pages: 1118-1127

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with alpha-fetoprotein promoter and Cre/lox P system.2001

    • Author(s)
      Sakai, Y., et al.
    • Journal Title

      J Virol Method 92

      Pages: 5-17

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Repression of Cyclin B1 Expression after Treatment with Adriamycin but Not Cisplatin in Human Lung Cancer A549 Cells.2001

    • Author(s)
      Dan, S., et al.
    • Journal Title

      Biochem Biophys Res Commun 280

      Pages: 861-867

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of tetraspanin CO-029 in hepatocellular carcinoma.2001

    • Author(s)
      Kanetaka, K., et al.
    • Journal Title

      J. Hepatol 35

      Pages: 637-642

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] DNA methyltransferase expression and DNA methylation of CpG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.2001

    • Author(s)
      Kanai, Y., et al.
    • Journal Title

      Int. J. Cancer 91

      Pages: 205-212

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis.2001

    • Author(s)
      Saito, Y., et al.
    • Journal Title

      Hepatology 33

      Pages: 561-568

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cloning and characterization of a novel gene, DRH1 down-regulated in advanced human hepatocellular carcinoma.2001

    • Author(s)
      Yamamoto, Y., et al.
    • Journal Title

      Clin. Cancer Res 7

      Pages: 297-303

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas.2001

    • Author(s)
      Imoto, I., et al.
    • Journal Title

      Cancer Res 61

      Pages: 6629-6634

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of target genes within an amplicon at 14q12-q13 in esophageal squamous cell carcinoma.2001

    • Author(s)
      Yasui, K., et al.
    • Journal Title

      Genes Chromosomes Cancer 32

      Pages: 112-118

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines.2001

    • Author(s)
      Tsuiki, H., et al.
    • Journal Title

      Oncogene 20

      Pages: 420-429

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells.2001

    • Author(s)
      Sudo, T., et al.
    • Journal Title

      EMBO J 20

      Pages: 6499-6508

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway.2001

    • Author(s)
      Okamoto, I., et al.
    • Journal Title

      J. Cell Biol 155

      Pages: 755-762

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multi-faceted analyses of a highly metastatic human lung cancer line NCI-H460 LNM35 suggest mimicry of inflammatory cells in metastasis2001

    • Author(s)
      Kozaki, K., et al.
    • Journal Title

      Oncogene 20

      Pages: 4228-4234

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Persistent increase in chromosome instability in lung cancer : indirect involvement of p53 inactivation.2001

    • Author(s)
      Haruki, N., et al.
    • Journal Title

      Am. J. Pathol 189

      Pages: 1345-1352

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association between the dopamine D2 receptor A2/A2 genotype and smoking behavior in the Japanese.2001

    • Author(s)
      Yoshida, K., et al.
    • Journal Title

      Cancer Epidemiol Biomark & Prev 10

      Pages: 403-405

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Definitive intraoperative very high-dose radiotherapy for localized osteosarcoma in the extremities.2001

    • Author(s)
      Oya, N., et al.
    • Journal Title

      Int. J. Radiat. Oncol. Biol. Phys. 51

      Pages: 87-93

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal adenocarcinoma.2001

    • Author(s)
      Inoue, H., et al.
    • Journal Title

      Genes Chromosomes Cancer 31

      Pages: 295-299

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] RIZ the retinoblastoma protein interacting zinc finger gene is mutated in genetically unstable cancers of the pancreas, stomach and colorectum.2001

    • Author(s)
      Sakurada, K., et al.
    • Journal Title

      Genes Chromosomes Cancer 30

      Pages: 207-211

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Elevated levels of connective tissue growth factor, WISP-1 and CYR61 in primary breast cancers associated with more advanced features.2001

    • Author(s)
      Xie, D., et al.
    • Journal Title

      Cancer Res 61

      Pages: 8917-8923

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chlorination of guanosine and other nucleosides by hypochlorous acid and myeloperoxidase of activated human neutrophils : Catalysis by nicotine and trimethylamine.2001

    • Author(s)
      Masuda, M., et al.
    • Journal Title

      J. Biol. Chem 276

      Pages: 40486-40496

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Effect of lycopene and Sho-saiko-to on hepatocarcinegesis in a rat model of spontaneous liver cancer.2001

    • Author(s)
      Watanabe, S., et al.
    • Journal Title

      Nutri. Cancer 39

      Pages: 96-101

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genomic structure of the human MAD2 gene and mutation analysis in human breast and lung cancers.2001

    • Author(s)
      Gemma, A., et al.
    • Journal Title

      Lung Cancer 32

      Pages: 289-295

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cloned mice from fetal fibroblast cells arrested at metaphase by a serial nuclear transfer.2001

    • Author(s)
      Ono, Y., et al.
    • Journal Title

      Biol. Reprod. 64

      Pages: 44-50

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Requirement of C3Glamda dependent Rap1 activation for cell adhesion and embryogenesis.2001

    • Author(s)
      Ohba, Y., et al.
    • Journal Title

      EMBO J. 20

      Pages: 3333-3341

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Requirement of phospholipase Cdelta4 for the zona pellucida-induced acrosome reaction.2001

    • Author(s)
      Fukami, K., et al.
    • Journal Title

      Science. 292

      Pages: 920-923

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Unique functions of Sonic hedgehog signaling during external genitalia development.2001

    • Author(s)
      Haraguchi, R., et al.
    • Journal Title

      Development 128

      Pages: 4241-4250

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells.2001

    • Author(s)
      Sakamoto, H., et al.
    • Journal Title

      Cln Cancer Res 7

      Pages: 2513-2518

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dephosphorylated hypqxia-inducible factor 1_as a mediator of p53-dependent apoptosis during hypoxia.2001

    • Author(s)
      Suzuki, H., et al.
    • Journal Title

      Oncogegne 20

      Pages: 5779-5788

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Antitumor action of the PKC activator gnidimacrin through CDK2 inhibition.2001

    • Author(s)
      Yoshida, M., et al.
    • Journal Title

      Int. J. Cancer 94

      Pages: 348-352

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.2001

    • Author(s)
      Yamamoto, Y., et al.
    • Journal Title

      Blood 97

      Pages: 2434-2439

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A facile and effective screening method for p21WAF1 promoter activator from microbial metabolites.2001

    • Author(s)
      Nie, L., et al.
    • Journal Title

      J. Antibiot 54

      Pages: 783-788

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Anti-tumor effect of b2-microglobulin in leukemic cells-bearing mice via apoptosis-inducing activity : Activation of caspase-3 and NF-kB.2001

    • Author(s)
      Mori, M., et al.
    • Journal Title

      Cancer Res 61

      Pages: 4414-4417

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Results of breast-conserving therapy for ductal carcinoma in situ : the Kyoto University experiences.2001

    • Author(s)
      Kokubo, M., et al.
    • Journal Title

      Breast Cancer 8

      Pages: 153-157

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Induction of MRP5 and SMRP mRNA by adriamycin exposure and its overexpression in human lung cancer cells resistant to adriamycin.2001

    • Author(s)
      Yoshida, M., et al.
    • Journal Title

      Int. J. Cancer 94

      Pages: 432-437

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nuclear factor-kappaB-dependent expression of metastasis suppressor KAI1/CD82 gene in lung cancer cell lines expressing mutant p53.2001

    • Author(s)
      Shinohara, T., et al.
    • Journal Title

      Cancer Res 61

      Pages: 637-678

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel variant of WISP 1 lacking a von Willebrand type C module overexpressed in scirrhous gastric carcinoma.2001

    • Author(s)
      Tanaka, S., et al.
    • Journal Title

      Oncogene 20

      Pages: 5525-5532

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] BAG-1M an isoform of Bcl-2-interacting protein BAG-1 enhances gene expression driven by CMV promoter.2001

    • Author(s)
      Takahashi, N.
    • Journal Title

      Biochem Biophys Res Commun 286

      Pages: 807-814

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Blockade of the extracellular signal-regulated kinase pathway induces marked G1 cell cycle arrest and apoptosis in tumor cells in which the pathway is constitutively activated : Up-regulation of p27Kip 1.2001

    • Author(s)
      Hoshino, R.
    • Journal Title

      J Biol Chem 276

      Pages: 2686-2692

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin.2001

    • Author(s)
      Furumai, R.
    • Journal Title

      Proc Natl Acad Sci USA 98

      Pages: 87-92

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cyclic Hydroxamic-acid-containing Peptide 31 a potent synthetic histone deacetylase inhibitor with antitumor activity.2001

    • Author(s)
      Komatsu, Y.
    • Journal Title

      Cancer Res 61

      Pages: 4459-66

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Interferon gamma-dependent induction of thymidine phosphorylase/platelet-derived endothelial growth factor through gamma-activated sequence-like element in human macrophages.2001

    • Author(s)
      Goto, H.
    • Journal Title

      Cancer Res 61

      Pages: 4459-66

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Regulation of activator protein-1 activity in the mediastinal lymph node metastasis of lung cancer.2001

    • Author(s)
      Ichiki K.
    • Journal Title

      Clin. Exp. Metastasis 18

      Pages: 539-545

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent-induced apoptosis.2001

    • Author(s)
      Mashima, T.
    • Journal Title

      J Cell Physiol 188

      Pages: 352-358

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Telomestatin a novel telomerase inhibitor from Streptomyces anulatus.2001

    • Author(s)
      Shin-ya, K.
    • Journal Title

      J. Am. Chem. Soc 123

      Pages: 1262-1263

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] In vitro reconstitution of the end replication problem.2001

    • Author(s)
      Ohki R
    • Journal Title

      Mol Cell Biol 21

      Pages: 5753-5766

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration2001

    • Author(s)
      Fukui, Y.
    • Journal Title

      Nature 412

      Pages: 826-31

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells.2001

    • Author(s)
      Takahashi, T.
    • Journal Title

      EMBO J 20

      Pages: 2768-78

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multifunctional strands in tight junctions.2001

    • Author(s)
      Tsukita, S.
    • Journal Title

      Nat Rev Mol Cell Biol 2

      Pages: 285-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53DINP1 a p53-inducible gene regulates p53-dependent apoptosis.2001

    • Author(s)
      Okamura, S.
    • Journal Title

      Mol Cell 8

      Pages: 85-94

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase.2001

    • Author(s)
      Toyoshima-Morimoto, F.
    • Journal Title

      Nature 410

      Pages: 215-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Related Articles : Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.2001

    • Author(s)
      Shimizu, K.
    • Journal Title

      EMBO J 21

      Pages: 294-302

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a PDZ domain containing golgi protein GOPC as an interaction partner of frizzled.2001

    • Author(s)
      Yao, R.
    • Journal Title

      Biochem Biophys Res Commun 286

      Pages: 771-778

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration.2001

    • Author(s)
      Kajita, M.
    • Journal Title

      J Cell Biol 153

      Pages: 893-904

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.2001

    • Author(s)
      Itoh, Y.
    • Journal Title

      EMBO J 20

      Pages: 4782-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cytoplasmic tail dependent internalization of membrane-type 1 matrix metalloproteinase (MT1-MMP) is important for its invasion-promoting activity.2001

    • Author(s)
      Uekita, T.
    • Journal Title

      J Cell Biol 155

      Pages: 1345-1356

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Induction of photoreceptor-specific phenotypes in adult mammalian iris tissue.2001

    • Author(s)
      Haruta, M.
    • Journal Title

      Nat Neurosci 4

      Pages: 1163-1164

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Glia-synapse Interaction through Ca2+-permeable AMPA receptors in Bergmann glia.2001

    • Author(s)
      Iino, M.
    • Journal Title

      Science 292

      Pages: 926-929

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Efficient gene activation in cultured mammalian cells mediated by FLP recombinase-expressing recombinant adenovirus.2001

    • Author(s)
      Nakano, M.
    • Journal Title

      Nucleic Acids Res 29, E40

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Adenovirus-mediated transfection of Caspase-8 augments anoikis and inhibits peritoneal dissemination of human gastric carcinoma cells.2001

    • Author(s)
      Nishimura, S.
    • Journal Title

      Cancer Res 61

      Pages: 7009-7014

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic and clinical features of human pancreatic ductal adenocarcinomas with widespread microsatellite instability.2001

    • Author(s)
      Yamamoto, H.
    • Journal Title

      Cancer Res 61

      Pages: 3139-3144

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Conversion of Zonula Occludentes from tight to leaky strand type by introducing claudin-2 into MDCK I cells.2001

    • Author(s)
      Furuse, M.
    • Journal Title

      J Cell Biol 153

      Pages: 263-272

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Junctional adhesion molecule (JAM) binds to PAR-3 : a possible mechanism for the recruitment of PAR-3 to tight junctions.2001

    • Author(s)
      Itoh, M.
    • Journal Title

      J Cell Biol 154

      Pages: 491-497

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in human pancreatic adeno-carcinomas : Clinicopathological and prognostic significance of matrilysin expression.2001

    • Author(s)
      Yamamoto, H.
    • Journal Title

      J Clin Oncol 19

      Pages: 1118-1127

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Gene therapy for hepatocellular carcinoma using two recombinant adenovirus vectors with alpha-fetoprotein promoter and Cre/lox P system.2001

    • Author(s)
      Sakai, Y.
    • Journal Title

      J Virol Method 92

      Pages: 5-17

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Repression of Cyclin B1 Expression after Treatment with Adriamycin but Not Cisplatin in Human Lung Cancer A549 Cells.2001

    • Author(s)
      Dan, S.
    • Journal Title

      Biochem Biophys Res Commun 280

      Pages: 861-867

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Overexpression of tetraspanin CO-029 in hepatocellular carcinoma.2001

    • Author(s)
      Kanetaka, K.
    • Journal Title

      J. Hepatol 35

      Pages: 637-642

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] DNA methyltransferase expression and DNA methylation of CpG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.2001

    • Author(s)
      Kanai, Y.
    • Journal Title

      Int. J. Cancer 91

      Pages: 205-212

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis.2001

    • Author(s)
      Saito, Y.
    • Journal Title

      Hepatology 33

      Pages: 561-568

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cloning and characterization of a novel gene, DRH1 down-regulated in advanced human hepatocellular carcinoma.2001

    • Author(s)
      Yamamoto, Y.
    • Journal Title

      Clin. Cancer Res 7

      Pages: 297-303

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas.2001

    • Author(s)
      Imoto, I.
    • Journal Title

      Cancer Res 61

      Pages: 6629-34

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of target genes within an amplicon at 14q12-q13 in esophageal squamous cell carcinoma.2001

    • Author(s)
      Yasui, K.
    • Journal Title

      Genes Chromosomes Cancer 32

      Pages: 112-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines.2001

    • Author(s)
      Tsuiki, H.
    • Journal Title

      Oncogene 20

      Pages: 420-429

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells.2001

    • Author(s)
      Sudo, T.
    • Journal Title

      EMBO J 20

      Pages: 6499-6508

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway.2001

    • Author(s)
      Okamoto, I.
    • Journal Title

      J. Cell Biol 155

      Pages: 755-762

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis.2001

    • Author(s)
      Kozaki, K.
    • Journal Title

      Oncogene 20

      Pages: 4228-4234

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Persistent increase in chromosome instability in lung cancer : possible indirect involvement of p53 inactivation.2001

    • Author(s)
      Haruki, N.
    • Journal Title

      Am. J. Pathol 189

      Pages: 1345-1352

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association between the dopamine D2 receptor A2/A2 genotype and smoking behavior in the Japanese.2001

    • Author(s)
      Yoshida, K.
    • Journal Title

      Cancer Epidemiol Biomark &Prev 10

      Pages: 403-405

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Definitive intraoperative very high-dose radiotherapy for localized osteosarcoma in the extremities.2001

    • Author(s)
      Oya, N.
    • Journal Title

      Int. J. Radiat. Oncol. Biol. Phys. 51

      Pages: 87-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal adenocarcinoma.2001

    • Author(s)
      Inoue, H.
    • Journal Title

      Genes Chromosomes Cancer 31

      Pages: 295-299

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] RIZ the retinoblastoma protein interacting zinc finger gene is mutated in genetically unstable cancers of the pancreas, stomach and colorectum.2001

    • Author(s)
      Sakurada, K.
    • Journal Title

      Genes Chromosomes Cancer 30

      Pages: 207-211

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Elevated levels of connective tissue growth factor, WISP-1 and CYR61 in primary breast cancers associated with more advanced features.2001

    • Author(s)
      Xie, D.
    • Journal Title

      Cancer Res 61

      Pages: 8917-8923

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Chlorination of guanosine and other nucleosides by hypochlorous acid and myeloperoxidase of activated human neutrophils : Catalysis by nicotine and trimethylamine.2001

    • Author(s)
      Masuda, M.
    • Journal Title

      J. Biol. Chem 276

      Pages: 40486-40496

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Effect of lycopene and Sho-saiko-to on hepatocarcinegesis in a rat model of spontaneous liver cancer.2001

    • Author(s)
      Watanabe, S.
    • Journal Title

      Nutri. Cancer 39

      Pages: 96-101

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genomic structure of the human MAD2 gene and mutation analysis in human breast and lung cancers.2001

    • Author(s)
      Gemma, A.
    • Journal Title

      Lung Cancer 32

      Pages: 289-295

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cloned mice from fetal fibroblast cells arrested at metaphase by a serial nuclear transfer.2001

    • Author(s)
      Ono, Y.
    • Journal Title

      Biol. Reprod. 64

      Pages: 44-50

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Requirement of C3Glamda dependent Rap1 activation for cell adhesion and embryogenesis.2001

    • Author(s)
      Ohba, Y.
    • Journal Title

      EMBO J. 20

      Pages: 3333-3341

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Requirement of phospholipase Cdelta 4 for the zona pellucida-induced acrosome reaction.2001

    • Author(s)
      Fukami, K.
    • Journal Title

      Science. 292

      Pages: 920-923

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Unique functions of Sonic hedgehog signaling during external genitalia development.2001

    • Author(s)
      Haraguchi, R.
    • Journal Title

      Development 128

      Pages: 4241-4250

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells.2001

    • Author(s)
      Sakamoto, H.
    • Journal Title

      Cln Cancer Res 7

      Pages: 2513-2518

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dephosphorylated hypoxia-inducible factor 1_as a mediator of p53-dependent apoptosis during hypoxia.2001

    • Author(s)
      Suzuki, H.
    • Journal Title

      Oncogene 20

      Pages: 5779-5788

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Antitumor action of the PKC activator gnidimacrin through CDK2 inhibition.2001

    • Author(s)
      Yoshida, M.
    • Journal Title

      Int. J. Cancer 94

      Pages: 348-352

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.2001

    • Author(s)
      Yamamoto, Y.
    • Journal Title

      Blood 97

      Pages: 2434-2439

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A facile and effective screening method for p21WAF1 promoter activator from microbial metabolites.2001

    • Author(s)
      Nie, L.
    • Journal Title

      J. Antibiot 54

      Pages: 783-788

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Anti-tumor effect of b2-microglobulin in leukemic cells-bearing mice via apoptosis-inducing activity : Activation of caspase-3 and NF-kB.2001

    • Author(s)
      Mori, M.
    • Journal Title

      Cancer Res 61

      Pages: 4414-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Results of breast-conserving therapy for ductal carcinoma in situ : the Kyoto University experiences.2001

    • Author(s)
      Kokubo, M.
    • Journal Title

      Breast Cancer 8

      Pages: 153-157

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Induction of MRP5 and SMRP mRNA by adriamycin exposure and its overexpression in human lung cancer cells resistant to adriamycin.2001

    • Author(s)
      Yoshida, M.
    • Journal Title

      Int. J. Cancer 94

      Pages: 432-437

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nuclear factor-kappaB-dependent expression of metastasis suppressor KAI1/CD82 gene in lung cancer cell lines expressing mutant p53.2001

    • Author(s)
      Shinohara, T.
    • Journal Title

      Cancer Res 61

      Pages: 637-678

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A novel variant of WISP 1 lacking a von Willebrand type C module overexpressed in scirrhous gastric carcinoma.2001

    • Author(s)
      Tanaka, S.
    • Journal Title

      Oncogene 20

      Pages: 5525-5532

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Anticancer and Some Biological Activities of Thiazinotrienomycin B.2000

    • Author(s)
      Hosokawa, N., et al.
    • Journal Title

      J Antibiot 53

      Pages: 306-308

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] I Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor 2-kinase.2000

    • Author(s)
      Cho S., et al.
    • Journal Title

      Biochem Biophys Acta 147

      Pages: 207-215

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a deletion mutant of DNA topoisomerase I cDNA from a camptothecin-resistant subline of human colon carcinoma cells.2000

    • Author(s)
      Yanase, K., et al.
    • Journal Title

      Jpn J Cancer Res 91

      Pages: 551-559

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The activity of soluble VCAM-1 in angiogenesis stimulated by IL-4 and IL-13.2000

    • Author(s)
      Fukushi, J., et al.
    • Journal Title

      J. Immunol 165

      Pages: 2818-2823

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis.2000

    • Author(s)
      Sakamoto, H., et al.
    • Journal Title

      Blood 95

      Pages: 3214-3218

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rasfonin a new apoptosis inducer in ras-dependent cells from Talaromyces sp.2000

    • Author(s)
      Tomikawa, T., et al.
    • Journal Title

      J. Antibiot 53

      Pages: 848-850

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of 2014 3 3 Proteins in Nuclear Localization of Telomerase2000

    • Author(s)
      Seimiya, H., et al.
    • Journal Title

      The EMBO Journal 19

      Pages: 2652-2661

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Asef a Link between the Tumor Suppressor APC and G-protein Signaling.2000

    • Author(s)
      Kawasaki, Y., et al.
    • Journal Title

      Science 289

      Pages: 1194-1197

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibition of Wnt signaling by ICAT a Novel b-catenin-interacting Protein.2000

    • Author(s)
      Tago, K., et al.
    • Journal Title

      Gense Dev. 14

      Pages: 1741-1749

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of a bone morphogenetic protein-responsive Smad binding element.2000

    • Author(s)
      Kusanagi, K., et al.
    • Journal Title

      Mol. Biol. Cell 11

      Pages: 555-565

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Smad6 is a Smadl/5-induced Smad inhibitor : Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter.2000

    • Author(s)
      Ishida, W., et al.
    • Journal Title

      J. Biol. Chem 275

      Pages: 6075-6079

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells.2000

    • Author(s)
      Mimori-Kiyosue, Y., et al.
    • Journal Title

      J.Cell Biol. 148

      Pages: 505-518

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Pores tin the wall : Claudins constitute tight junction strands containing aqueous pores.2000

    • Author(s)
      Tsukita, Sh., et al.
    • Journal Title

      J.Cell Biol. 149

      Pages: 13-16

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] (review) Aging clock the watchmaker's masterpiece.2000

    • Author(s)
      Ishikawa, F., et al.
    • Journal Title

      Cell. Mol. Life Sci. 57

      Pages: 698-704

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase.2000

    • Author(s)
      Tatematsu, K., et al.
    • Journal Title

      Genes to Cells 5

      Pages: 677-688

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death.2000

    • Author(s)
      Kurokawa, M., et al.
    • Journal Title

      EMBO J 19

      Pages: 2958-2968

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Acetylation of GATA-3 affects T-cell survival and homing to secondary Iymphoid organs.2000

    • Author(s)
      Yamagata, T., et al.
    • Journal Title

      EMBO J 19

      Pages: 4676-4687

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Two cell adhesion molecules Nectin and Cadherin interact through their cytoplasmic domain-associated proteins.2000

    • Author(s)
      Tachibana, K., et ai.
    • Journal Title

      J. Cell Biol. 150

      Pages: 1161-1176

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.2000

    • Author(s)
      Kodama, A., et al.
    • Journal Title

      Mol. Biol. Cell 11

      Pages: 2565-2575

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mmh/Oggl gene inactivation results in accumulation of 8-hydroxyguanine in mice.2000

    • Author(s)
      Minowa, O., et al.
    • Journal Title

      Proc Natl Acad Sci USA 97

      Pages: 4156-4161

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Negative regulation of BMP/Smad signaling by Tob in osteoblasts.2000

    • Author(s)
      Yoshida, Y., et al.
    • Journal Title

      Cell 103

      Pages: 1085-1097

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Targeted disruption of the homeobox transcription factor Bapxl results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation.2000

    • Author(s)
      Akazawa, H., et al.
    • Journal Title

      Genes to Cells 5

      Pages: 499-513

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inactivation of 2014 3 3 sigma gene is associated with 5' CpG island hypermethylation in human cancers.2000

    • Author(s)
      Suzuki, H., et al.
    • Journal Title

      Cancer Res 60

      Pages: 4353-4357

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53-inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation.2000

    • Author(s)
      Takekawa, T., et al.
    • Journal Title

      EMBO J 19

      Pages: 6517-6525

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-type 6 matrix metalloproteinase (MT6-MMP MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP.2000

    • Author(s)
      Kojima, S., et al.
    • Journal Title

      FEBS Lett 480

      Pages: 142-146

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] R Transformation of Madin-Darbycanine kidney (MDCK) epithelial cells by Epstein-Barr virus latent membrane protein 1 (LMP1) induces expression of Ets1 and invasive growth.2000

    • Author(s)
      Kim, K., et al.
    • Journal Title

      Oncogene 19

      Pages: 1764-1771

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor.2000

    • Author(s)
      Nabeshima, K., et al.
    • Journal Title

      Cancer Res 60

      Pages: 3364-3369

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice.2000

    • Author(s)
      Takiguchi, M., et al.
    • Journal Title

      Life Sci 66

      Pages: 991-1001

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Complex phenotype of mice lacking occludin a component of tight junction strands.2000

    • Author(s)
      Sitou, M., et al.
    • Journal Title

      Mol Cell Biol 11

      Pages: 4131-4142

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Isolation of a novel gene on 8p21 3-22 whose expression is reduced significantly in human colorectal cancers with liver metastasis.2000

    • Author(s)
      Oyama, T., et al.
    • Journal Title

      Genes Chromosomes Cancer 29

      Pages: 9-15

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis - a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma2000

    • Author(s)
      Kondo, Y., et al.
    • Journal Title

      Hepatology 32

      Pages: 970-979

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nonrandom chromosomal Imbalances in esophageal squamous cell carcinoma cell lines : Possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon.2000

    • Author(s)
      Pimkhaokham, A., et al.
    • Journal Title

      Jpn J Cancer Res 91

      Pages: 1126-1133

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] CD44 is a potential target of amplification within the 11p13 amplicon detected in four of 25 gastric cancer cell lines.2000

    • Author(s)
      Fukuda, Y., et al.
    • Journal Title

      Genes Chromosome Cancer 29

      Pages: 315-324

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Amplification and overexpression of TGIF2 a novel homeobox gene of the TALE superclass in ovarian cancer cell lines.2000

    • Author(s)
      Imoto, I., et al.
    • Journal Title

      Biochem Biophys Res Commun 276

      Pages: 264-270

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a novel gene, GASC1 within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines.2000

    • Author(s)
      Yang, ZQ., et al.
    • Journal Title

      Cancer Res 60

      Pages: 1034245-1034245

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Allelic loss at 1p34-36 predicts poor prognosis in node-negative breast cancer.2000

    • Author(s)
      Utada, Y., et al.
    • Journal Title

      Clin. Cancer Res 6

      Pages: 3193-3198

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mapping of target regions of allelic loss in primary breast cancers to 1-cM intervals on genomic contings at 6q21 and 6q25 32000

    • Author(s)
      Utada, Y., et al.
    • Journal Title

      Jpn. J. Cancer Res 91

      Pages: 293-300

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cytotoxic T lymphocyte responses elicited to Wilms' tumor gene WT1 product by DNA vaccination.2000

    • Author(s)
      Tsuboi, A., et al.
    • Journal Title

      J Clin Immunol 20

      Pages: 195-202

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Human cytotoxic T lymphocyte responses specific for peptides of wild-type Wilms' tumor gene WT1 product.2000

    • Author(s)
      Oka, Y., et al.
    • Journal Title

      Immunogenetics 51

      Pages: 99-107

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cancer Immunotherapy targeting Wilms' tumor gene WT1 product.2000

    • Author(s)
      Oka, Y., et al.
    • Journal Title

      J Immunol 164

      Pages: 1873-1880

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] In vivo selected human lung cancer cell line NCI-H460-LNM35 consistently exhibits lymphogenous metastasis via both subcutaneous and orthotopic propagation.2000

    • Author(s)
      Kozaki, K., et al.
    • Journal Title

      Cancer Res 60

      Pages: 2535-2540

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Translin binds to the sequences adjacent to the breakpoints of the TLS and CHOP genes in liposarcomas with translocation t(12;16).2000

    • Author(s)
      Hosaka, T., et al.
    • Journal Title

      Oncogene 19

      Pages: 1430776-1430776

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Intra-operative radiation therapy for osteosarcoma in the extremities.2000

    • Author(s)
      Tsuboyama, T., et al.
    • Journal Title

      Int. Orthop 24

      Pages: 202-207

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] High incidence of SV40-like sequences detection in tumour and peripheral blood cells of Japanese osteosarcoma patients.2000

    • Author(s)
      Yamamoto, H., et al.
    • Journal Title

      Br. J. Cancer 82

      Pages: 1677-1681

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association of poor prognosis with loss of 12q, 17p and 18q and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma.2000

    • Author(s)
      Yatsuoka, T., et al.
    • Journal Title

      Am. J. Gastroent 95

      Pages: 2080-2085

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of Rad51 alteration in patients with bilateral breast cancer.2000

    • Author(s)
      Kato, M., et al.
    • Journal Title

      J. Hum. Genet. 45

      Pages: 133-137

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Microsatellite genotyping of post-PCR fluorescently labeled markers.2000

    • Author(s)
      Chawengchao, B., et al.
    • Journal Title

      BioTechniques 29

      Pages: 868-872

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Analysis of p53 tumor suppressor gene somatic mutation in rheumatoid arthritis synovium.2000

    • Author(s)
      Inazuka, M., et al.
    • Journal Title

      Rheumatology 39

      Pages: 262-266

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence : an 11-year follow-up study of a general population.2000

    • Author(s)
      Imai, K., et al.
    • Journal Title

      Lancet 356

      Pages: 1795-1799

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes.2000

    • Author(s)
      McIlroy, D., et al.
    • Journal Title

      Genes Dev. 14

      Pages: 549-558

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sequential cloning of mice to six generations.2000

    • Author(s)
      Wakayama, T., et al.
    • Journal Title

      nature 407

      Pages: 318-319

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Requirement of CD9 on the egg plasma membrane for fertilization.2000

    • Author(s)
      Miyado, K., et al.
    • Journal Title

      Science 287

      Pages: 321-324

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Proteasome inhibition circumvents solid tumor resistance to topoisomerase II- directed drugs.2000

    • Author(s)
      Ogiso, Y., et al.
    • Journal Title

      Cancer Res 60

      Pages: 2429-2434

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Modulation of akt kinase activity by binding to Hsp90.2000

    • Author(s)
      Sato, S., et al.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 97

      Pages: 10832-10837

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] U0126 reverses Ki-ras mediated transformation by blocking both MAP kinase and p70 S6 kinase pathways.2000

    • Author(s)
      Fukazawa, H., et al.
    • Journal Title

      Cancer Res 60

      Pages: 2104-2107

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Problems in the development of target-based drugs.2000

    • Author(s)
      Saijo, N., et al.
    • Journal Title

      Cancer Chemother. Pharmacol 46

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MUM1/IRF4 expression as a frequent event in mature lymphoid malignancies.2000

    • Author(s)
      Tsuboi, K., et al.
    • Journal Title

      Leukemia 14

      Pages: 449-456

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutations of Plk gene lead to instability of Plk protein in human cancer cell lines.2000

    • Author(s)
      Simizu, S., et al.
    • Journal Title

      Nat. Cell Biol 2

      Pages: 852-854

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nuclear Localization signals of the BRCA2 protein.2000

    • Author(s)
      Yano, K., et al.
    • Journal Title

      Biochem. Biophys. Res. Commun 270

      Pages: 171-175

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genomic alterations in primary gastric cancers analyzed by comparative genomic hybridization and clinicopathological factors.2000

    • Author(s)
      Nakanishi.M., et al.
    • Journal Title

      Hepato-Gastroenterology 47

      Pages: 658-662

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A new apoptotic pathway for the complement factor B-derived fragment Bb.2000

    • Author(s)
      Uwai, M., et al.
    • Journal Title

      J. Cell Physiol 185

      Pages: 280-292

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Analysis of genetic polymorphism in NQOl.GST-Ml.GST-T1.and CYP3A4 in 469 Japanese patients with therapy-related leukemia/myelodysplastic syndrome and de novo acute myeloid leukemia.2000

    • Author(s)
      Naoe, T., et al.
    • Journal Title

      Cln. Cancer Res 6

      Pages: 4091-4095

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Enhanced Cell Killing by Overexpression of Dominant-negative Phosphatidylinositol 3-Kinase Subunit, Deltap85 Following Genotoxic Stresses.2000

    • Author(s)
      Tachiiri, S., et al.
    • Journal Title

      Jpn. J. Cancer Res 91

      Pages: 1314-1318

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Phase I and pharmacologic study of docetaxel and irinotecan in advanced non-small-cell lung cancer.2000

    • Author(s)
      Masuda, N., et al.
    • Journal Title

      J. Clin. Oncol 18

      Pages: 2996-3003

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Natural killer cell-dependent suppression of systemic spread of human lung adenocarcinoma cells by monocyte chemoattractant protein-1 gene transfection in severe combined immunodeficient mice.2000

    • Author(s)
      Nokihara, H., et al.
    • Journal Title

      Cancer Res 60

      Pages: 7002-7007

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Time trends of surgical treatment and the prognosis for Japanese patients with gastric cancer.2000

    • Author(s)
      Maehara, Y., et al.
    • Journal Title

      Br. J. Cancer 83

      Pages: 986-991

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Anticancer and Some Biological Activities of Thiazinotrienomycin B.2000

    • Author(s)
      Hosokawa, N.
    • Journal Title

      J Antibiot 53

      Pages: 306-308

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor 2-kinase.2000

    • Author(s)
      Cho S. I.
    • Journal Title

      Biochem Biophys Acta 1475

      Pages: 207-215

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a deletion mutant of DNA topoisomerase I cDNA from a camptothecin-resistant subline of human colon carcinoma cells.2000

    • Author(s)
      Yanase, K.
    • Journal Title

      Jpn J Cancer Res 91

      Pages: 551-559

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The activity of soluble VCAM-1 in angiogenesis stimulated by IL-4 and IL-13.2000

    • Author(s)
      Fukushi, J.
    • Journal Title

      J. Immunol 165

      Pages: 2818-2823

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis.2000

    • Author(s)
      Sakamoto, H.
    • Journal Title

      Blood 95

      Pages: 3214-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Rasfonin a new apoptosis inducer in ras-dependent cells from Talaromyces sp.2000

    • Author(s)
      Tomikawa, T.
    • Journal Title

      J. Antibiot 53

      Pages: 848-850

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of 2014.3.3 Proteins in Nuclear Localization of Telomerase.2000

    • Author(s)
      Seimiya, H.
    • Journal Title

      The EMBO Journal 19

      Pages: 2652-2661

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Asef a Link between the Tumor Suppressor APC and G-protein Signaling.2000

    • Author(s)
      Kawasaki, Y.
    • Journal Title

      Science 289

      Pages: 1194-1197

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inhibition of Wnt signaling by ICAT a Novel b-catenin-interacting Protein.2000

    • Author(s)
      Tago, K
    • Journal Title

      Gense Dev. 14

      Pages: 1741-1749

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Characterization of a bone morphogenetic protein-responsive Smad binding element.2000

    • Author(s)
      Kusanagi, K.
    • Journal Title

      Mol. Biol. Cell 11

      Pages: 555-565

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Smad6 is a Smad1/5-induced Smad inhibitor : Characterization of bone morphogenetic protein-responsive element in the mouse Smad6 promoter.2000

    • Author(s)
      Ishida, W.
    • Journal Title

      J. Biol. Chem 275

      Pages: 6075-6079

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells.2000

    • Author(s)
      Mimori-Kiyosue, Y.
    • Journal Title

      J. Cell Biol. 148

      Pages: 505-518

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Pores tin the wall : Claudins constitute tight junction strands containing aqueous pores2000

    • Author(s)
      Tsukita, Sh.
    • Journal Title

      J. Cell Biol. 149

      Pages: 13-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] (review) Aging clock the watchmaker's masterpiece.2000

    • Author(s)
      Ishikawa, F.
    • Journal Title

      Cell. Mol. Life Sci. 57

      Pages: 698-704

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase.2000

    • Author(s)
      Tatematsu, K.
    • Journal Title

      Genes to Cells 5

      Pages: 677-688

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] The Evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death.2000

    • Author(s)
      Kurokawa, M.
    • Journal Title

      EMBO J 19

      Pages: 2958-2968

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs.2000

    • Author(s)
      Yamagata, T.
    • Journal Title

      EMBO J 19

      Pages: 4676-4687

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Two cell adhesion molecules Nectin and Cadherin interact through their cytoplasmic domain-associated proteins.2000

    • Author(s)
      Tachibana, K.
    • Journal Title

      J.Cell Biol. 150

      Pages: 1161-1176

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering.2000

    • Author(s)
      Kodama, A.
    • Journal Title

      Mol. Biol. Cell 11

      Pages: 2565-2575

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice.2000

    • Author(s)
      Minowa, O.
    • Journal Title

      Proc Natl Acad Sci USA 97

      Pages: 4156-4161

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Negative regulation of BMP/Smad signaling by Tob in osteoblasts.2000

    • Author(s)
      Yoshida, Y.
    • Journal Title

      Cell 103

      Pages: 1085-1097

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Targeted disruption of the homeobox transcription factor Bapx1 results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation.2000

    • Author(s)
      Akazawa, H.
    • Journal Title

      Genes to Cells 5

      Pages: 499-513

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Inactivation of 2014.3.3 sigma gene is associated with 5' CpG island hypermethylation in human cancers.2000

    • Author(s)
      Suzuki, H.
    • Journal Title

      Cancer Res 60

      Pages: 4353-4357

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] p53-inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation.2000

    • Author(s)
      Takekawa, T.
    • Journal Title

      EMBO J 19

      Pages: 6517-6525

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Membrane-type 6 matrix metalloproteinase (MT6-MMP MMP-25) is the second glycosyl-phosphatidyl inositol (GPI)-anchored MMP.2000

    • Author(s)
      Kojima, S.
    • Journal Title

      FEBS Lett 480

      Pages: 142-146

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Transformation of Madin-Darbycanine kidney (MDCK) epithelial cells by Epstein-Barr virus latent membrane protein 1 (LMP1) induces expression of Ets1 and invasive growth.2000

    • Author(s)
      Kim, K.R.
    • Journal Title

      Oncogene 19

      Pages: 1764-1771

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Front-cell-specific expression of membrane-type 1 matrix metalloproteinase and gelatinase A during cohort migration of colon carcinoma cells induced by hepatocyte growth factor/scatter factor.2000

    • Author(s)
      Nabeshima, K.
    • Journal Title

      Cancer Res 60

      Pages: 3364-3369

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] CTLA4IgG gene delivery prevents autoantibody production and lupus nephritis in MRL/lpr mice.2000

    • Author(s)
      Takiguchi, M.
    • Journal Title

      Life Sci 66

      Pages: 991-1001

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Complex phenotype of mice lacking occludin a component of tight junction strands.2000

    • Author(s)
      Sitou, M.
    • Journal Title

      Mol Cell Biol 11

      Pages: 4131-4142

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Isolation of a novel gene on 8p21.3-22 whose expression is reduced significantly in human colorectal cancers with liver metastasis.2000

    • Author(s)
      Oyama, T.
    • Journal Title

      Genes Chromosomes Cancer 29

      Pages: 9-15

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis-a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma.2000

    • Author(s)
      Kondo, Y.
    • Journal Title

      Hepatology 32

      Pages: 970-979

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nonrandom chromosomal Imbalances in esophageal squamous cell carcinoma cell lines : Possible involvement of the ATF3 and CENPF genes in the 1q32 amplicon.2000

    • Author(s)
      Pimkhaokham, A.
    • Journal Title

      Jpn J Cancer Res 91

      Pages: 1126-33

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] CD44 is a potential target of amplification within the 11p13 amplicon detected in four of 25 gastric cancer cell lines.2000

    • Author(s)
      Fukuda, Y.
    • Journal Title

      Genes Chromosome Cancer 29

      Pages: 315-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Amplification and overexpression of TGIF2 a novel homeobox gene of the TALE superclass in ovarian cancer cell lines.2000

    • Author(s)
      Imoto, I.
    • Journal Title

      Biochem Biophys Res Commun 276

      Pages: 264-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of a novel gene, GASC1 within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines.2000

    • Author(s)
      Yang, Z.Q.
    • Journal Title

      Cancer Res 60

      Pages: 4735-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Allelic loss at 1p34-36 predicts poor prognosis in node-negative breast cancer.2000

    • Author(s)
      Utada, Y.
    • Journal Title

      Clin. Cancer Res 6

      Pages: 3193-3198

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mapping of target regions of allelic loss in primary breast cancers to 1-cam intervals on genomic contings at 6q21 and 6q25.3.2000

    • Author(s)
      Utada, Y.
    • Journal Title

      Jpn. J. Cancer Res 91

      Pages: 293-300

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cytotoxic T lymphocyte responses elicited to Wilms' tumor gene WT1 product by DNA vaccination.2000

    • Author(s)
      Tsuboi, A.
    • Journal Title

      J Clin Immunol 20

      Pages: 195-202

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Human cytotoxic T lymphocyte responses specific for peptides of wild-type Wilms' tumor gene WT1 product.2000

    • Author(s)
      Oka, Y.
    • Journal Title

      Immunogenetics 51

      Pages: 99-107

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Cancer Immunotherapy targeting Wilms' tumor gene WT1 product.2000

    • Author(s)
      Oka, Y.
    • Journal Title

      J Immunol 164

      Pages: 1873-1880

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] In vivo selected human lung cancer cell line NCI-H460-LNM35 consistently exhibits lymphogenous metastasis via both subcutaneous and orthotopic propagation.2000

    • Author(s)
      Kozaki, K.
    • Journal Title

      Cancer Res 60

      Pages: 2535-2540

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Translin binds to the sequences adjacent to the breakpoints of the TLS and CHOP genes in liposarcomas with translocation t(12;16).2000

    • Author(s)
      Hosaka, T.
    • Journal Title

      Oncogene 19

      Pages: 5821-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Intra-operative radiation therapy for osteosarcoma in the extremities.2000

    • Author(s)
      Tsuboyama, T.
    • Journal Title

      Int. Orthop 24

      Pages: 202-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] High incidence of SV40-like sequences detection in tumor and peripheral blood cells of Japanese osteosarcoma patients.2000

    • Author(s)
      Yamamoto, H.
    • Journal Title

      Br. J. Cancer 82

      Pages: 1677-81

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Association of poor prognosis with loss of 12q, 17p and 18q and concordant loss of 6q/17p and 12q/18q in human pancreatic ductal adenocarcinoma.2000

    • Author(s)
      Yatsuoka, T.
    • Journal Title

      Am. J. Gastroent 95

      Pages: 2080-2085

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Identification of Rad51 alteration in patients with bilateral breast cancer.2000

    • Author(s)
      Kato, M.
    • Journal Title

      J. Hum. Genet. 45

      Pages: 133-137

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Microsatellite genotyping of post-PCR fluorescently labeled markers.2000

    • Author(s)
      Chawengchao, B.
    • Journal Title

      BioTechniques 29

      Pages: 868-872

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Analysis of p53 tumor suppressor gene somatic mutation in rheumatoid arthritis synovium.2000

    • Author(s)
      Inazuka, M.
    • Journal Title

      Rheumatology 39

      Pages: 262-266

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence : an 11-year follow-up study of a general population.2000

    • Author(s)
      Imai, K.
    • Journal Title

      Lancet 356

      Pages: 1795-1799

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes.2000

    • Author(s)
      McIlroy, D.
    • Journal Title

      Genes Dev. 14

      Pages: 549-558

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Sequential cloning of mice to six generations.2000

    • Author(s)
      Wakayama, T.
    • Journal Title

      nature 407

      Pages: 318-319

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Requirement of CD9 on the egg plasma membrane for fertilization.2000

    • Author(s)
      Miyado, K.
    • Journal Title

      Science 287

      Pages: 321-324

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs.2000

    • Author(s)
      Ogiso, Y.
    • Journal Title

      Cancer Res 60

      Pages: 2429-2434

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Modulation of akt kinase activity by binding to Hsp90.2000

    • Author(s)
      Sato, S.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 97

      Pages: 10832-10837

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] U0126 reverses Ki-ras mediated transformation by blocking both MAP kinase and p70 S6 kinase pathways.2000

    • Author(s)
      Fukazawa, H.
    • Journal Title

      Cancer Res 60

      Pages: 2104-2107

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Problems in the development of target-based drugs.2000

    • Author(s)
      Saijo, N.
    • Journal Title

      Cancer Chemother. Pharmacol 46

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] MUM1/IRF4 expression as a frequent event in mature lymphoid malignancies.2000

    • Author(s)
      Tsuboi, K.
    • Journal Title

      Leukemia 14

      Pages: 449-456

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Mutations of Plk gene lead to instability of Plk protein in human cancer cell lines.2000

    • Author(s)
      Simizu, S.
    • Journal Title

      Nat. Cell Biol 2

      Pages: 852-854

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Nuclear Localization signals of the BRCA2 protein.2000

    • Author(s)
      Yano, K.
    • Journal Title

      Biochem. Biophys. Res. Commun 270

      Pages: 171-175

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Genomic alterations in primary gastric cancers analyzed by comparative genomic hybridization and clinic pathological factors.2000

    • Author(s)
      Nakanishi, M.
    • Journal Title

      Hepato-Gastroenterology 47

      Pages: 658-662

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] A new apoptotic pathway for the complement factor B-derived fragment Bb.2000

    • Author(s)
      Uwai, M.
    • Journal Title

      J. Cell Physiol 185

      Pages: 280-292

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Analysis of genetic polymorphism in NQO1,GST-M1,GST-T1,and CYP3A4 in 469 Japanese patients with therapy-related leukemia/myelodysplastic syndrome and de novo acute myeloid leukemia.2000

    • Author(s)
      Naoe, T.
    • Journal Title

      Cln. Cancer Res 6

      Pages: 4091-4095

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Enhanced Cell Killing by Overexpression of Dominant-negative Phosphatidylinositol 3-Kinase Subunit, Deltap85 Following Genotoxic Stresses.2000

    • Author(s)
      Tachiiri, S.
    • Journal Title

      Jpn. J. Cancer Res 91

      Pages: 1314-1318

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Phase I and pharmacologic study of docetaxel and irinotecan in advanced non-small-cell lung cancer.2000

    • Author(s)
      Masuda, N.
    • Journal Title

      J. Clin. Oncol 18

      Pages: 2996-3003

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Natural killer cell-dependent suppression of systemic spread of human lung adenocarcinoma cells by monocyte chemoattractant protein-1 gene transfection in severe combined immunodeficient mice.2000

    • Author(s)
      Nokihara, H.
    • Journal Title

      Cancer Res 60

      Pages: 7002-7007

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Time trends of surgical treatment and the prognosis for Japanese patients with gastric cancer.2000

    • Author(s)
      Maehara, Y.
    • Journal Title

      Br.J.Cancer 83

      Pages: 986-991

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates.

    • Author(s)
      Yamanaka, H., et al.
    • Journal Title

      EMBO Rep 3

      Pages: 69-75

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates.

    • Author(s)
      Yamanaka, H
    • Journal Title

      EMBO Rep 3

      Pages: 69-75

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Epigenetic inactivation of CHFR in human tumors.

    • Author(s)
      Toyota, M
    • Journal Title

      Proc Natl Acad Sci USA 100

      Pages: 7818-7823

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Journal Article] Dynamic behavior of paired claudin strands within apposing plasma membranes.

    • Author(s)
      Sasaki, H
    • Journal Title

      Proc Natl Acad Sci USA 100

      Pages: 3971-3976

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2005 Final Research Report Summary
  • [Publications] Tsuruo, T., et al.: "Molecular targeting therapy of cancer : drug resistance, apoptosis and survival signal."Cancer Sci.. 94. 15-21 (2003)

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  • [Publications] Yamamoto, K., et al.: "Polycomb group suppressor of zeste 12 links heterochromatin protein lalpha and enhancer of zeste 2."J Biol Chem.. 279. 401-406 (2004)

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  • [Publications] Asada, M., et al.: "ADIP, a novel afadin- and a -actinin-binding protein localized at cell-cell adherens junctions."J.Biol.Chem.. 278. 4103-4111 (2003)

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  • [Publications] Kimura, T., et al.: "Impaired function of p53R2 in Rrm2b-null mice causes severe_renal_failure through attenuation of dNTP pools."Nature Genetics. 34. 440-445 (2003)

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      2003 Annual Research Report
  • [Publications] Inoue, M., et al.: "Epidemiology of pancreatic cancer in Japan : nested case-control study from the hospital-based Epidemiologic research program at Aichi Cancer Center (HERPACC)."Int.J.Epidemiol.. 32. 257-262 (2003)

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  • [Publications] Takaoka, A., et al.: "Integration of IFN- α/β signalling to p53 responses in tumor suppression and antiviral defense."Nature. 424. 516-523 (2003)

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      2003 Annual Research Report
  • [Publications] Sato, S.: "Regulation of kinase activity of3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3"J. Biol. Chem.. 277. 39360-39367 (2002)

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  • [Publications] Morishima, Y., et al.: "The clinical significance of HLA allele compatibility in patients transplanted with marrow from a serologically HLA-A, B and DR matched unrelated donor"Blood. 99. 4200-4206 (2002)

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  • [Publications] Shinohara, M., et al.: "Roles of cell-cell adhesion-dependent tyrosine phosphorylation of Gab-1"J. Biol. Chem.. 276. 18941-18946 (2001)

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      2002 Annual Research Report
  • [Publications] Okamura, S., et al.: "p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis"Molecular Cell. 8. 85-94 (2001)

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  • [Publications] Takezaki, T., et al.: "The hOGG1 ser326cys polymorphism and modification by environmental factors of stomach cancer risk in Chinese"Int. J. Cancer. 99. 624-627 (2002)

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  • [Publications] Takayanagi, H., et al.: "RANKL maintains bone homeostasis through c-Fos-dependent induction of IFN-beta"Nature. 416. 744-749 (2002)

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  • [Publications] Tsuruo, T., et al.: "Involvement of Hsp9O in signaling and stability of 3-Phsphoinositide-dependent kinase-1"J. Biol. Chem.. (in press).

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  • [Publications] Sasazuki, T., et al.: "Hematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration"Nature. 412. 826-831 (2001)

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  • [Publications] Takai, Y., et al.: "Roles of cell-cell adhesion-dependent tyrosine phosphorylation of Gab-1"J. Biol. Chem.. 276. 18941-18946 (2001)

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      2001 Annual Research Report
  • [Publications] Y.Nakamura., et al.: "p53DINP1, a p53-Inducible gene, regulates p53-dependent apoptosis"Molecular Cell. 8. 85-94 (2001)

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  • [Publications] Tajima, K., et al.: "Association between folate and methionine related polymorphisms and malignant lymphoma risk"Blood. 97. 3205-3209 (2001)

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  • [Publications] Taniguchi, T., et al.: "RANKL maintains bone homeostasis through c-Fos-dependent induction of IFN-β"Nature. (in press).

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  • [Publications] Seimiya,H., et al.: "Involvement of 14-3-3 proteins in nuclear localization of telomerase."EMBOJ.. 19. 2652-2661 (2000)

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  • [Publications] Ries S., et al.: "Opposing effects of Ras on p53 : Transcriptional Activation of mdm2 and induction of p19^<ARF>."Cell. 103. 321-330 (2000)

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  • [Publications] Kodama,A., et al.: "Involvement of an SHP-2-Rho small G protein pathway in hepatocyte, growth factor/scatter factor-induced cell scattering."Mol.Biol.Cell. 11. 2565-2575 (2000)

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  • [Publications] Oda K, et al.: "Isolation of a novel gene encoding a mitochondrial protein, p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser46-phosphorylated p53."Cell. 102. 849-862 (2000)

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  • [Publications] Tajima,K.and Sonoda,S.: "Origins of HTLV-I with South America."Nature Med.. 6. 232-233 (2000)

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  • [Publications] Takayanagi,H., et al.: "T-cell-mediated regulation of osteocrastogenesis by signalling cross-talk between RANKL and IFN-gamma."Nature. 408. 600-605 (2000)

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  • [Publications] Dan, S.: "Activation of c-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells"Oncogene. 18. 1277-1283 (1999)

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  • [Publications] Mashima, T.: "Caspase-mediated cleavage of tytoskeletal actin plays a positive role in the process of morphological apoptosis"Oncogene. 18. 2423-2430 (1999)

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  • [Publications] Ogiso, Y.: "Glucose starvation and hypoxia induce nuclear accumulation of proteasome in cancer cells"Biochem. Biophys. Res. Commum.. 259. 448-452 (1999)

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  • [Publications] Hirotani, M.: "NH_2-terminal BH4 domain of Bcl-2 is functional for heterodimenrization with bax and inhibition of apoptosis"J. Biol. Chem.. 274. 20415-20420 (1999)

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  • [Publications] Naasani, I.: "FJ5002: A potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis"Cancer Res.. 59. 4004-4011 (1999)

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  • [Publications] Yamori, T.: "Potent antitumor activity of MS-247, a novel DNA minor groove binder, evaluated by an in vitro and ino vivo human cancer cell line panel"Cancer Res.. 59. 4042-4049 (1999)

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Published: 1999-04-01   Modified: 2018-03-28  

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