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Steering committe on study of medaka as a model for organization and evolution of the nuclear genome

Research Project

Project/Area Number 11236101
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionThe University of Tokyo

Principal Investigator

SHIMA Akihiro  The University of Tokyo, Graduate school of Frontier Sciences, Professor Emeritus, 大学院・新領域創成科学研究科, 名誉教授 (60011590)

Co-Investigator(Kenkyū-buntansha) SHIMIZU Nobuyoshi  Keio University, School of Medicine, Professor, 医学部, 教授 (50162706)
NAGAHAMA Yoshitaka  National Institute for Basic Biology, Professor, 基礎生物学研究所, 教授 (50113428)
SUZUKI Norio  Hokkaido University, Graduate School of Science, Professor, 大学院・理学研究科, 教授 (20082133)
SHIROISHI Toshihiko  National Institute of Genetics, Mammalian Genetics Laboratory, Professor, 系統生物センター, 教授 (90171058)
岩槻 邦男  放送大学学園, 放送大学・教養学部, 教授 (10025348)
Project Period (FY) 1999 – 2003
Project Status Completed (Fiscal Year 2003)
Budget Amount *help
¥17,300,000 (Direct Cost: ¥17,300,000)
Fiscal Year 2003: ¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2002: ¥3,600,000 (Direct Cost: ¥3,600,000)
Fiscal Year 2001: ¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2000: ¥3,200,000 (Direct Cost: ¥3,200,000)
Fiscal Year 1999: ¥3,400,000 (Direct Cost: ¥3,400,000)
Keywordsmedaka genome / Medaka Genome Initiative (MGI) / International collaboration / International symposium / research resources / メダカゲノムイニシアチブ / EMBO Course / MGI / Symposium on Medaka Genomics 2002 / 拡大班会議 / メダカゲノムプロジェクト / 定例班会議 / 班会議 / 中間ヒアリング / 課題名の発展的変更 / メダカゲノムシークエンシング / Medaka Genome Initiatives(MGI) / 総括班会議 / 知的所有権 / 公開シンポジュウム / 公開講座「メダカの学校2001」 / 市民 / 基礎知識の啓蒙 / メダカの特性 / 国際協力
Research Abstract

1. Advices and suggestions were made on each project on the occasion of the annual meetings for progress reporting.
2. Two members of the Priority Area #813 (M. Nonaka and H. Mitani) were sent as instructors for the EMBO Course held in the EBML, Heidelberg, Germany, in July, 2002.
3. Three members of the Priority Area #813 (N. Shimizu, S. Asakawa and T. Sasaki) were sent to Medaka Genome Initiative (MGI) Symposiun on Medaka Genomics held in the EMBL on July 3 1 and August 1, 2002
4. To close the 5 years term of the Priority Area #813, an international symposium was organized, under joint auspice of the ERATO Kondoh Differentiation Signaling Project on "Medaka Genome and Vertebrate Evolution" on March 3 and 4 2004 in Tokyo with over 1 20 participants.

Report

(6 results)
  • 2003 Annual Research Report   Final Research Report Summary
  • 2002 Annual Research Report
  • 2001 Annual Research Report
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (33 results)

All Other

All Publications (33 results)

  • [Publications] Naruse K.: "A Detailed Linkage Map of Medaka, Oryzias latipes. Comparative genomics and genome evolution."Genetics. 154. 1773-1784 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kondo S: "The medaka rs-3 locus required for scale development encodes ectodysplasin-A receptor."Current Biology. 11. 1202-1206 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kondo M.: "Differences in recombination frequencies during female and male meioses of the sex chromosomes of the medaka, Oryzias latipes."Genet.Res.. 78. 23-30 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Shimada, A.: "High incidence of mosaic mutations induced by irradiating paternal germ cells of the medaka fish, Oryzias latipes."Mutation Research. 495. 33-42 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Fukamachi, S.: "Genomic analysis of gamma-ray-induced germ-cell mutations at the b locus recovered from the medaka specific-locus test."Mutation Research. 458. 19-29 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Fukamachi, S.: "A. Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medaka."Nature Genetics. 28. 381-385 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kuwahara, Y.: "A critical stage in spermatogenesis for radiation-induced cell death in the medaka fish, Oryzias latipes."Radiation Research. 157. 386-392 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Shimada, A.: "Induction and characterization of mutations at the b locus of the medaka, Oryzias latipes."Zoological Science. 19. 411-417 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Wittbrodt, J.: "Medaka-A model organism from the Far East."Nature Reviews Genetics. 3. 53-64 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Shima, A.: "Fish genomes flying - Symposium on Medaka genomics."EMBO reports. 4. 121-125 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Aizawa, K.: "The medaka midblastula transition as revealed by the expression of the paternal genome."Gene Expression Patterns. 3. 43-47 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kuwahara, Y.: "Gamma-ray exposure accelerates spermatogenesis of medaka fish, Oryzias latipes."Molecular Reproduction and Development. 65. 204-211 (2003)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Naruse K., Fukamachi S., Mitani H., Kondo M., Matsuoka T., Kondo S., Hanamura N., Morita Y., Hasegawa K., Nishigaki R., Shimada A., Wada H., Kusakabe T., Suzuki N., Kinoshita M., Kanamori A., Terado T., Kimura H., Nonaka M., Shima A.: "A Detailed Linkage Map of Medaka, Oryzias latipes. Comparative genomics and genome evolution."Geneti cs.. 154. 1773-1784 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kondo S, Kuwahara Y., Kondo M., Naruse K., Mitani H., Wakamatsu Y., Ozato K., Asakawa S., Shimizu N., Shima, A.: "The media rs-3 locus required for scale development encodes ectodvsplasin-A receptor."Current Biology. 11. 1202-1206 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kondo M., Nagao E., Mitani H., Shima A.: "Differences in recombination frequencies during female and male meioses of the sex chromosomes of the medaka, Oryzias latipes."Genet. Res.. 78. 23-30 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Okubo K., Nagata S., Ko R., Kataoka H., Yoshiura Y., Mitani, H., Kondo M., Naruse K., Shima A., Aida, K.: "Identification and Characterization of Two Distinct GnRH Receptor Subtypes in a Teleost, the Medaka Oryzias latipes."Endocrinology. 142. 4729-4739 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Shimada, A., Shima, A.: "High incidence of mosaic mutations induced by irradiating paternal germ cells of the medaka fish, Oryzias latipes."Mutation Research. 495. 33-42 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Fukamachi, S., Shimada A., Naruse, K., Shima A.: "Genomic analysis of gamma-ray-induced germ-cell mutations at the b locus recovered from the medaka specific-locus test."Mutation Research. 458. 19-29 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Fukamachi, S., Shimada, A., Shima, A.: "Mutations in the gene encoding B, a novel transporter protein, reduce melanin content in medaka."Nature Genetics. 28. 381-385 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kuwahara, Y., Shimada, A., Mitani, H., Shima, A.: "A critical stage in spermatogenesis for radiation-induced cell death in the medaka fish, Oryzias latipes."Radiation Research. 157. 386-392 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Nakayama, K., Kuakamachi, S., Kimura, H., Koda, Y., Soemantri, A., Ishida, T.: "Distinctive distribution of AIM1 polymorphism among major human populations with different skin color."Journal of Human Genetics. 47. 92-94 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Shimada, A., Fukamachi, S., Wakamatsu, Y., Ozato, K., Shima, A.: "Induction and characterization of mutations at the b locus of the medaka, Oryzias latipes."Zoological Science. 19. 411-417 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Wittbrodt, J., Shima, A., Schartl, M.Medaka: "A model organism from the Far East."Nature Reviews Genetics. 3. 53-64 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Shima, A., Himmelbauer, H., Mitani, H., Furutani-Seiki, M., Wittbrodt, J., Schartl, M.: "Fish genomes flying-Symposium on Medaka genomics."EMBO reports. 4. 121-125 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Aizawa, K., Shimada, A., Naruse, K., Mitani, H., Shima, A.: "The medaka midblastula transition as revealed by the expression of the paternal genomes."Gene Expression Patterns. 3. 43-47 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Kuwahara, Y., Shimada, A., Mitani, H., Shima, A.: "Gammaray exposure accelerates spermatogenesis of medaka fish, Oryzias latipes."Molecular Reproduction and Development. 65. 204-211 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2003 Final Research Report Summary
  • [Publications] Shima, A., Himmelbauer, H.--: "Fish genomes flying - Symposium on Medaka genomics."EMBO reports. Vol.4. 121-125 (2003)

    • Related Report
      2003 Annual Research Report
  • [Publications] Nanda, I., M.Kondo, U.Hornung, S.Asakawa, C.Winkler, A.Shimizu, Z.Shan, T.Haaf, N.Shimizu, A.Shima, M.Schmid, M.Schartl: "A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes"Proc. Natl. Acad. Sci., U.S.A.. 99. 11778-11783 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Okubo, K., H.Mitani, K.Naruse, M.Kondo, A.Shima, M.Tanaka, S.Asakawa, N.Shimizu, Y.Yoshiura, K.Aida: "Structural characterization of GnRH loci in the medaka genome"Gene. 293. 181-189 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Kondo, M., A.Froschauer, A.Kitano, A., I.Nanda, U.Hornung, J.-N.Volff, S.Asakawa, H.Mitani, K.Naruse, M.Tanaka, M.Schmid, N.Shimizu, M.Schartl, A.Shima: "Molecular cloning and characterization of DMRT genes from the medaka Oryzias latipes and the platyfish Xiphophorus maculates"Gene. 295. 213-222 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Shimada, A., S.Fukamachi, Y.Wakamatsu, K.Ozato, A.Shima: "Induction and characterization of mutations at the b locus of the medaka, Oryzias latipes"Zool. Sci.. 19. 411-417 (2002)

    • Related Report
      2002 Annual Research Report
  • [Publications] Shima, A., H.Himmelbauer, H.Mitani, M.Furutani-Seiki, J.Wittbrodt, M.Schartl: "Fish genomes flying-Symposium on Medaka genomics"EMBO reports. 4. 121-125 (2003)

    • Related Report
      2002 Annual Research Report
  • [Publications] J.Wittbrodt, A.Shima, M.Schartl: "Medaka -A Model Organism from the Far East"Nature Reviews Genetics. 3巻1号. 53-64 (2002)

    • Related Report
      2001 Annual Research Report

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Published: 1999-04-01   Modified: 2018-03-28  

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