• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of medicinal plant resources of liverworts growing in southern hemisphere and research for the clucidation of the evolution and differentiation process based on the precision chemical analysis.

Research Project

Project/Area Number 11309012
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field 広領域
Research InstitutionFaculty of Pharmaceutical Sciences, Tokushima Bunri University

Principal Investigator

ASAKAWA Yoshinori  Faculty of Pharmaceutical Sciences, Tokushima Bunri University, prodessor,, 薬学部, 教授 (50033874)

Co-Investigator(Kenkyū-buntansha) TOYOTA Masao  Faculty of Pharmaceutical Sciences, Tokushima Bunri University,, 薬学部, 助手 (50122586)
HASHIMOTO Toshihiro  Faculty of Pharmaceutical Sciences, Tokushima Bunri University,, 薬学部, 助教授 (10075955)
FUKUYAMA Yoshiyasu  Faculty of Pharmaceutical Sciences, Tokushima Bunri University, prodessor,, 薬学部, 教授 (70208990)
NAGASHIMA Fumihiro  Faculty of Pharmaceutical Sciences, Tokushima Bunri University,, 薬学部, 助手 (60228012)
Project Period (FY) 1999 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥23,010,000 (Direct Cost: ¥22,800,000、Indirect Cost: ¥210,000)
Fiscal Year 2001: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2000: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 1999: ¥21,300,000 (Direct Cost: ¥21,300,000)
KeywordsBryophytes / Liverworts / Ferns / LC-MS / GC-MS / Seswuiterpenes / Evolution / Bibenzyls / LS-MS / GC-MS / 化学系統分類 / ケモシステマティクス / 芳香族化合物 / 辛味成分 / ニュージーランド / セスキテルペン / テルペノイド / ゼニゴケ / クサリゴケ / ビスビベンジル
Research Abstract

We focused on the chemical constituents of the liverworts and ferns in southern hemisphere, as many endemic species are growing in New Zealand and Argentine. The constituents isolated from the liverworts based on the micro chemical analysis, are important for the chemosystematic and evolutionary study of the liverworts. We also compared between the chemical constituents of the liverworts and those of ferns by LC-MS and GC-MS analysis.
1.The ether extract of Argentine Dumortiera hirsuta and Plagiochasma rupestre were analysed. Former species contained two novel sesquiterpenes, named as dumortane and nordumortane-type skeletons. Latter species produced hopane-type triterpenoid, which is important chemical indicator for the chemosystematics of Reboulia hemisphaerica and P. rupestre. Ecuadorian Leptoscyphus jackii was analysed chemically to identify a number of new sesquiterpenes, maaliane and germacrane types. The volatile vinylbenzenoids were found as fragrance of the Ecuadorian liverwort … More s Marchesinia brachiata.
2.250 materials were collected in New Zealand, and the number of species was estimated as about 100.New Zealand Riccardia species were analysed chemically to give new sesquiterpenoid as a major constituent. 12 Radula species were analysed chemically and they were divided into four chemo-taxa with their constituents. Further investigation of the ether extract of Radula marginata resulted in the isolation of cannabinoid structure-related compound which was expected to show an interesting biological activity.
3.Pungent tasting compounds distributed in liverworts (Porella and Plagiochila etc) are known. New Zealand liverwort Hymenophyton flabellatum contained 1-(2, 4, 6-trimethoxy-phenyl)-but-2-en-1-one as the pungent tasting constituent. This is the most important result for the discussion of the evolutionary line of liverworts and ferns in the present investigation, since the same pungent compounds were also contained in the fern, Arachinoides standishii. Perrottetin H classified into bibenzyl compound, which is widely distributed in the liverworts, but not found in constituents of higher plants, yet. The Japanese ferm Hymenophyllum barbatum contained bisbibenzyl, Perrottetin H. These two compounds are chemical fossils, contained both in the liverworts and ferns. Less

Report

(4 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (107 results)

All Other

All Publications (107 results)

  • [Publications] Aboutabl, E.: "Aromatic compounds from the Egyptian moss Eucladium verticillatum (BIRD) B.S.G."J.Hattori Bot.Lab.. 86. 175-178 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Bardon, A.: "A 7-nordumortane and other dumortane derivatives from the Argentine liverwort Dumortiera hirsuta"Phytochemistry. 51(2). 281-287 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Bardon, A.: "Sesquiterpenoids, hopanoids and bis (bi-benzyls) from the Argentine liverwort Plagiochasma rupestre"Phytochemistry. 52(7). 1323-1329 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto, T.: "Ptychantols A-C, macrocyclic bis(bibenzyls), possessing a trans-stilbene structure from the liverwort Ptychanthus striatus"Phytochemistry. 52(3). 501-509 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "A novel skeletal diterpenoid from the German liverwort Barbilophozia hatcheri (Evans.) Loeske"Chem.Pharm.Bull.. 47(1). 138-139 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "Sesqui-and diterpenoids from Ptilidium ciliare and Barbilophozia species (Liverworts)"Phytochemistry. 51(4). 563-566 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "New acorane-and cuparane-type sesqui-and new labdane-and seco-labdane-type diterpenoids from the Japanese liverwort Jungermannia infusca (Mitt.) Steph"Tetrahedron. 55(30). 9117-9132 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "Aromatic compounds from the Ecuadorian liverwort Marchesinia brachiata : a Revision"Phytochemistry. 51(8). 1101-1104 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Oiso, Y.: "Occurrence of digalactopyranosylmonoacyl-glycerol in the liverwort Marchantia polymorpha"J.Hattori Bot.Lab.. 86. 169-174 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Oiso, Y.: "Occurrence of a bis-bibenzyl derivative in the Japanese Fern Hymenophyllum barbatum : First isolation of perrottetin H from the pteridophytes"Chem.Pharm.Bull.. 47(2). 297-298 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "Terpenoid constituents of the liverwort Reboulia hemisphaerica"Phytochemistry. 52(1). 105-112 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "The absolute configuration of eudesmane-type sesquiterpenoids found in the liverwort Chiloscyphus polyanthos"Phytochemistry. 51(7). 913-920 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "A revision of the positive sign of the optical rotation and its maximum value of α-Eudesmol"Phytochemistry. 52(4). 689-694 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "Sesquiterpenoids and cyclic bis (bibenzyls) from the Pakistani liverwort Plagiochasma appendiculatum"J.Hattori Bot.Lab.. 86. 161-167 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "A revision of the^<13>C NMR spectral assignment of globulol"Spectroscopy. 14(2). 61-66 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.: "Chemical structures of macrocyclic bis (bibenzyls) isolated from liverworts (Hepaticae)"Spectroscopy. 14. 149-175 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Fukuyama, Y.: "Structures, Biological Activities and Total Synthesis of Cyclic Bisbibenzyls from Liverworts"Journal of Synthetic Organic Chemistry, Japan. 58(7). 654-665 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto, T.: "Pinguisane-and dimeric pinguisane-type sesquiterpenoids from the Japanese liverwort Porella acutifolia subsp. tosana"Phytochemistry. 53(5). 593-604 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "Sesqui-and Diterpenoids from the Japanese liverwort Jungermannia infusca (Mitt.) Steph"J.Nat.Prod.. 64(10). 1309-1317 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "seco-Cuparane-type sesquiterpenoid from the Japanese liverwort Jungermannia infusca"Phytochemistry. 56(8). 807-810 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "Sesqui-and Diterpenoids from two Japanese and three European Liverworts"Phytochemistry. 56(4). 347-352 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "A new halimane-type diterpenoid from the liverwort Jungermannia infusca"Fitoterapia. 72(1). 83-85 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Oiso, Y.: "Hymenosides A-F, six new hemiterpene glucosides from the Japanese fern Hymenophyllum barbatum"Chem.Pharm.Bull.. 49(1). 126-128 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "New Chroman Derivatives from the Japanese Liverworts Metacalypogeia cordifolia and Cephalozia otaruensis"Chem.Pharm.Bull.. 49(7). 924-926 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "New Bitter-Tasting Hemiterpene Glycosides from Japanese Fern Hymenophyllum barbatum"Chem.Pharm.Bull.. 49(12). 1567-1572 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Bardon, A.: "Eremophilanolides and other constituents from the Argentine liverwort Frullania brasiliensis"Phytochemistry. 59(2). 205-213 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "New Glycosides from the Japanese Fern Hymenophyllum barbatum"Chem.Pharm.Bull.. 50(4)(in Press). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto, T.: "New chlorinated cyclic bis (bibenzyls) from the liverworts, Herbertus sakuraii and Mastigophora diclados"Tetrahedron. 56. 3153-3159 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto, T.: "Chemical constituents of the liverworts Herbertus sakuraii and Herbertus aduncus"J.Hattori Bot.Lab.. 89. 267-282 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Irita, H.: "Herbertane-type sesquiterpenoids from the liverwort Herbertus sakuraii"Phytochemistry. 55(3). 247-253 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Lahlou, B.H.: "Highly oxygenated sesquiterpenes from the liverwort Trocholejeunea sandvicensis"Phytoehemistry. 53(2). 271-276 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Lahlou, E.H..: "Chemical Constituents of the Liverworts Plagiochasma japonica and Marchantia tosana"J.Hattori Bot.Lab.. 88(8). 271-275 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.: "Clerodane-type diterpenoids from the liverwort Jungermannia infusca (Mitt.) Steph"Chem.Pharm.Bull.. 48(11). 1818-1821 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "Chemical constituents of three liverworts Frullania inflata, Leptoscyphus jackii and Wiesnerella denudata"J.Hattori Rot.Lab.. 89. 289-297 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "Phytochemical study of liverworts Conocephalum conicum and Chiloscyphus polyanthos"Yakugaku Zasshi. 120(12). 1359-1372 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.: "Recent advances in phytochemistry of bryoghytes-acetogenins, terpenoids and bis (bibenzyl)s from selected Japanese, Taiwanese, New Zealand, Argentinean and European liverworts"Phytochemistry. 56(3). 297-312 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.: "Occurrence of Polygodial and 1-(2,4,6-Trimethoxyphenyl)-but-2-en-1-one from Some Ferns and Liverworts : Role of Pungent Components in Bryophytes and Pteridophytes Evolution"Chem.Pharm.Bull.. 49(10). 1380-1381 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.: "Sesquiterpene lactones and acetogenin lactones from the hepaticae and chemosystematics of the liverworts Frullania, Plagiochila and Porella"Heterocycles. 54(2). 1057-1093 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.: "Constituyentes bioactivos de hepaticas.Importancia de las especies Americanas"Rev.Latinoamer.Quim.. 29(1). 5-22 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.: "Phytochemistry of Bryophytes : Recent advances in phytochemistry, volume 33,Phytochemicals in Human Health Protection, Nutrition, and Plant Defense"J.T.Romeo. 24 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Aboutabl, E.. Afifi, M.Ghanem, N.Yokoyama, R.Fukuyama, Y. and Asakawa, Y: "Aromatic compounds from the Egyptian moss Eucladium verticillatum(BORD)B.S.G"J. Hattori Bot. Lab. 86. 175-178 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Bardon, A.Kamiya, N.Toyota, M.and Asakawa, Y.: "A 7-nordumortane and other dumortance derivatives from the Argentine liverwort Dumortiera hirsuta"Phytochemistry. 51. 281-287 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Bardon, A.Kamiya, N.Toyota, M, Takaoka, S. and Asakawa, Y: "Sesquiterpenoids, Hopanoids and bis(bi-benzyls) from the Argentine liverwort Plagiochasma rupestra."Phytochemistry. 52(7). 1323-1329 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto, T.Ikeda, H.Takaoka, S.Tanaka, M. and Asakawa, Y: "Ptychantols A-C, macrocyclic bis(bibenzyls), possessing a trans-stilbene structure from the liverwort Ptychanthus striatus."Phytochemistry. 52(3). 501-509 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.Murakami, Y. and Asakawa, Y: "A novel skeletal diterpenoid from the German liverwort Barbilophozia hatcheri (Evans.) Loeske."Chem. Pharm. Bull.. 47(1). 138-139 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.Takaoka, S.Huneck, S. and Asakawa, Y: "Sesqui-and diterpenoids from Ptilidium ciliare and Barbilophozia species (Liverworts)."Phytochemistry. 51(4). 563-566 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.Suzuki, M.Takaoka, S. and Asakawa, Y: "New Acorane- and cuparane-type sesqui- and new labdane- and seco-labdane-type diterpenoids from the Japanese liverwort Jungermannia infusca(Mitt.) Steph."Tetrahedron,. 55(30). 9117-9132 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.Murakami, Y. and Asakawa, Y: "Aromatic compounds from the Ecuadorian liverwort Marchesinia brachiata : a Revesion."Phytochemistry. 51(8). 1101-1104 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Oiso, Y.Toyota, M. and Asakawa, Y: "Occurrence of digalactopyranosylmono acyl-glycerol in the liverwort Marchantia polymorpha."J. Hattori Bot. Lab. 86. 169-174 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Oiso, Y.Toyota, M. and Asakawa, Y: "Occurrence of a bis-bibenzyl derivative in the Japanese Fern Hymenophyllum barbatum : First isolation of perrottetin H from the pteridophytes"Chem. Pharm. Bull. 47(2). 297-298 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.Konoshima, M. and Asakawa, Y: "Terpenoid constituents of the liverwort Reboulia hemisphaerica."Phytochemistry. 52(1). 105-112 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.Saito, T. and Asakawa, Y: "The absolute configuration of eudesmane-type sesquiterpenoids found in the liverwort Chiloscyphus polyanthos."Phytochemistry. 51(7). 913-920 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.Yonehara, Y.Horibe, I.Minagawa, K. and Asakawa, Y: "A revision of the positive sign of the optical rotation and its maximum value of αーEudesmol."Phytochemistry. 52(4). 689-694 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M. and Asakawa, Y: "Sesquiterpenoids and cyclic bis (bibenzyls) from the Pakistani liverwort Plagiochasma appendiculatum."J. Hattori Bot. Lab.. 86. 161-167 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.Tanaka, M. and Asakawa, Y: "A revesion of the 13^C NMR spectral assignment of globulol."Spectroscopy. 14(2). 61-66 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y. Toyota, M.Tori, M. and Hashimoto, T.: "Chemical structures of macrocyclic bis (bibenzyls) isolated from liverworts (Hepaticae)."Spectroscopy. 14. 149-175 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Fukuyama, Y.Kodama, M. and Asakawa, Y: "Structures, Biological Activities and Total Synthesis of Cyclic Bisbibenzyls from Liverworts."Journal of Synthetic Organic Chemistry. Japan. 58(7). 654-665 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto, T.Irita, H.Tanaka, M.Takaoka, S. and Asakawa, Y: "Pinguisane^and dimeric pinguisane-type sesquiterpenoids from the Japanese liverwort Porella acutifolia subsp.tosana."Phytochemistry. 53(5). 593-604 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto, T.Irita, H.Takaoka, S.Tanaka, M. and Asakawa, Y: "New chlorinated cyclic bis(bibenzyls) from the liverworts, Herbertus sakuraii and Mastigophora diclados."Tetrahedron,. 56. 3153-3159 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Hashimoto, T.Toyota, M.Irita, H. and Asakawa, Y: "Chemical constituents of the liverworts Herbertus sakuraii and Herbertus aduncus."J. Hattori Bot. Lab. 89. 267-282 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Lahlou, E.H. Hashimoto, T. and Asakawa, Y: "Chemical Constituents of the Liverworts Plagiochasma japonica and Marchantia tosana."J. Hattori Bot. Lab. 88(8). 271-275 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Lahlou, E.H. Hashimoto, T.and Asakawa, Y: "Highly oxygenated sesquiterpenes from the liverwort Trocholejeunea sandvicensis"Phytochemistry. 53(2). 271-276 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Irita, H.Hashimoto, T.Fukuyama, Y. and Asakawa, Y: "Herbertane-type sesquiterpenoids from the liverwort Herbertus sakuraii"Phytochemistry. 55(3). 247-253 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.Suzuki, M.Takaoka, S. and Asakawa, Y: "Clerodane-type diterpenoids from the liverwort Jungermannia infusca (Mitt.) Steph."Chem. Pharm. Bull.. 48(11). 1818-1821 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.Kondo, K.Konoshima, M. and Asakawa.Y: "Chemical constituents of three liverworts Frullania inflata, Leptoscyphus jackii and Wiesnerella denudata."J. Hattori Bot. Lab. 89. 289-297 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.: "Phytochemical study of liverworts Conocephalum conicum and Chiloscyphus polyanthos."Yakugaku Zasshi. 120(12). 1359-1372 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.: "Recent advances in phytochemistry of bryophytes-acetogenins, terpenoids and bis (bibenzyl)s from selected Japanese, Taiwanese, New Zealand, Argentinean and European liverworts."Phytochemistry. 56(3). 297-312 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.Toyota, M.Oiso, Y. and Braggins, J.E..: "Occurrence of polygodial and 1-(2, 4, 6-Trimethoxyphenyl)-but-2-en-1-one from Some ferns and liverworts : Role of pungent components in bryophytes and pteridophytes evolution."Chem. Pharm. Bull.. 49(10). 1380-1381 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.Toyota, M.Nagashima, F.Hashimoto, T. and Lahlou, E.H.: "Sesquiterpene lactones and acetogenin lactones from the hepaticae and chemosystematics of the liverworts Frullania, Plagiochila and Porella."Heterocycles. 54(2). 1057-1093 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y. and Bardon, A: "Constituyentes bioactivos de hepaticas Importancia de las especies Americanas."Rev. Latinoamer. Quim. 29(1). 5-22 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.Suzuki, M.Takaoka, S. and Asakawa, Y: "Sesqui- and deterpenoids from the Japanese liverwort Jungermannia infusca(Mitt.) Steph."J. Nat. Prod.. 64(10). 1309-1317 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.Suzuki, M.Takaoka, S. and Asakawa, Y: "Seco-Cuparane-type sesquiterpenoid from the Japanese liverwort Jungermannia infusca."Phytochemistry. 56(8). 807-810 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.and Asakawa, Y: "Sesqui-and diterpenoids from two Japanese and three European liverworts"Phytochemistry. 56(4). 347-352 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Nagashima, F.Suzuki, M. and Asakawa, Y: "A new halimane-type diterpenoid from the liverwort Jungernannia infusca."Fitoterapia. 72(1). 83-85 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Oiso, Y.Toyota, M. and Asakawa, Y: "Hymenosides A-F six new hemiterpene glucosides from the Japanese fern Hymenophyllum barbatum."Chem. Pharm. Bull. 49(1). 126-128 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.Oiso, Y. and Asakawa, Y: "New bitter-tasting hemiterpene glycosides from Japanese fern Hymenophyllum barbatum."Chem. Pharm. Bull.. 49(12). 1567-1572 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.Omatsu, I. and Asakawa, Y: "New chroman derivatives from the Japanese liverworts Metacalypogeia cordifolia and Cephalozia otaruensis."Chem. Pharm. Bull.. 49(7). 924-926 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Bardon, A.Mitre, G.B. Kamiya, N.Toyota, M. and Asakawa, Y: "Eremophilanolides and other constituents from the Argentine liverwort Frullania brasiliensis."Phytochemistry. 59(2). 205-213 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Toyota, M.Oiso, Y. and Asakawa, Y: "New glycosides from the Japanese fern Hymenophyllum barbatum."Chem. Pharm. Bull. 50 (inpress). (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Asakawa, Y.: "Constituyentes bioactivos de hepaticas. Importancia de las especies Americanas"Rev.Latinoamer. Quim. 29(1). 5-22 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Asakawa, Y.: "Sesquiterpene lactones and acetogenin lactones from the hepaticac and chemosystematics of the liverworts Frullania, Plagiochila and Porella"Heterocycles. 54(2). 1057-1093 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Asakawa, Y.: "Occurrence of Polygodial and 1-(2,4,6-Trimethoxyphenyl)-but-2-en-1-one from Some Ferns and Liverworts: Role of Pungent Components in Bryophytes and Pteridophytes Evolution"Chem.Pharm.Bull. 49(10). 1380-1381 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Nagashima, F.: "Sesqui-and Diterpenoids from the Japanese liverwort Jungermannia infusca(Mitt.) Steph"J.Nat.Prod.. 64(10). 1309-1317 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Nagashima, F.: "seco-Cuparane-type sesquiterpenoid from the Japanese liverwort Jungermannia infusca"Phytochemistry. 56(8). 807-810 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Nagashima, F.: "Sesqui-and Diterpenoids from two Japanese and three European Liverworts"Phytochemistry. 56(4). 347-352 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Nagashima, F.: "A new halimane-type diterpenoid from the liverwort Jungermannia infusca"Fitoterapia. 72(1). 83-85 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Oiso, Y.: "Hymenosides A-F, six new hemiterpene glucosides from the Japanese fern Hymenophyllum barbatum"Chem.Pharm.Bull. 49(1). 126-128 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Toyota, M.: "New Chroman Derivatives from the Japanese Liverworts Metacalypogeia cordifolia and Cephalozia otaruensis"Chem.Pharm.Bull. 49(7). 924-926 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Toyota, M.: "New Bitter-Tasting Hemiterpene Glycosides from Japanese Fern Hymenophyllum barbatum"Chem.Pharm.Bull. 49(12). 1567-1572 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Bardon, A.: "Eremophilanolides and other constituents from the Argentine liverwort Frullania brasiliensis"Phytochemistry. 59(2). 205-213 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Toyota, M.: "New Glycosides from the Japanese Fern Hymenophyllum barbatum"Chem.Pharm.Bull. 50(4)(in Press). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] Asakawa,Y.: "Chemical structures of macrocyclic bib (bibenzys) isolated from liverworts (Hepaticae)."Spectroscopy. 14. 149-175 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Toyota,M: "Chemical constituents of three liverworts Frullania inflata,Leptoscyphus jackii and Wiesnerella denudata."J.Hattori Bot.Lab.. 89. 289-297 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hashimoto,T.: "Chemical constituents of the liverworts Herbertus sakuraii and Herbertus aduncus."J.Hattori Bot.Lab. 89. 267-282 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Nagashima,F.: "Clerodane-type diterpenoids from the liverwort Jungermannia infusca (Mitt.) Steph."Chem.Pharm.Bull.. 48(11). 1818-1821 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hashimoto,T.,: "New chlorinated cyclic bis (bibenzlys) from the liverworts, Herbertus sakuraii and Mastigophora diclados."Tetrahedron. 56. 3153-3159 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Hashimoto,T.,: "Pinguisane-and dimeric pinguisane-type sesquiterpenoids from the Japanese liverwort Porella acutifolia subsp.tosana."Phytochemistry. 53. 593-604 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] A.Bardon,N.Kamiya,M.Toyota and Y.Asakawa: "A 7-nordumortane and other dumortane derivatives from Argentine liverwort Dumortiera hirsuta."Phytochemistry. 51(4). 281-287 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] F.Nagashima,Y.Murakami and Y.Asakawa: "Aromatic compounds from the Ecuadorian liverwort Marchesinia brachiata:a revision."Phytochemistry. 51(8). 1101-1104 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] M.Tiyota,M.Konoshima and Y.Asakawa: "Terpenoid constituents of the liverwort Reboulia hemisphaerica."Phytochemistry. 52(1). 105-112 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] T.Hashimoto,H.Ikeda,S.Takaoka,M.Tanaka and Y.Asakawa: "Ptychantols A-C,macrocyclic bis(bibenzyls),possessing a trans-stilbene structure from the liverwort Ptychantus striatus."Phytochemsitry. 52(3). 501-509 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] M.Toyota,Y.Yonehara,I.Horibe,K.Minagawa and Y.Asakawa: "A revision of the positive sign of the optical rotation and its maximum value of alpha-eudesmol."Phytochemistry. 52(4). 689-694 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] A.Bardon,N.Kamiya,M.Toyota,S.Takaoka and Y.Asakawa: "Sesquiterpenoids,hopanoids and bis(bibenzyls)from the Argentine liverwort Plagiochama rupestre."Phytochemistry. 52(7). 1321-1329 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] S.Friederich,M.Reffer,Y.Asakawa and M.H.Zenk: "Cytochromes P-450 ctalyze the formation of marchantin A and C in Marchantia polymorpha."Phytochemistry. 52(7). 1195-1202 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] E.-H.Lahou,M.Hashimoto and Y.Asakawa: "Highly oxygeneated sesquiterpenes from the livwrwort Trocholejeunea sandvicensis."Phytochemistry. 53(2). 271-276 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] M.Toyota,M.Tanaka and Y.Asakawa: "A revision of the 13C NMR spectral assignment of globulol."Spectroscopy. 14(2). 61-66 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] M.Toyota,K.Kondo,M.Konoshima and Y.Asakawa: "Chemical constituents of three liverworts Frullania inflata,Leptoscyphus jackii and Wiesnerella denudata."Journal Hattori Botanical Laboratory(JHBL). (in press). (2000)

    • Related Report
      1999 Annual Research Report

URL: 

Published: 1999-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi