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Development of The Technology of Biomagnetic Measurement Using High-Temperature Superconductor

Research Project

Project/Area Number 11359001
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section展開研究
Research Field 広領域
Research InstitutionHokkaido University

Principal Investigator

KURIKI Shinya  Hokkaido University, Research Institute for Electronic Science, Professor, 電子科学研究所, 教授 (30002108)

Co-Investigator(Kenkyū-buntansha) MATSUDA Mizushi  Muroran Institute of Technology, School of Engineering, Associate Professor, 工学部, 助教授 (20261381)
TAKEUCHI Fumiya  Hokkaido University, Research Institute for Electronic Science, Lecturer, 電子科学研究所, 助手 (30281835)
HIRATA Yosihiro  Hokkaido University, Research Institute for Electronic Science, Lecturer, 電子科学研究所, 助手 (30250509)
Project Period (FY) 1999 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥30,110,000 (Direct Cost: ¥28,400,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2001: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2000: ¥10,700,000 (Direct Cost: ¥10,700,000)
Fiscal Year 1999: ¥12,000,000 (Direct Cost: ¥12,000,000)
KeywordsHigh-temperature superconductor / SQUID / Biomagnetism / Magnetocardiogram / Magnetic shielding
Research Abstract

Under the aim to develop the technology of biomagnetic measurement using high-Tc superconductor, we made the following studies and obtained the results described.
1. Directly coupled magnetometers were fabricated from YBCO films to have a field noise of less than 100 fT/Hz^<1/2>. The magnetometers have fine structures of slots and holes in μm size on the whole superconducting film and flux dams in the lead film that connects the pickup coil to the SQUID, so that entry and trapping of magnetic flux in the superconducting film would be suppressed. As a result, the magnetometers did not exhibit appreciable increase of low-frequency flux-noise when they were cooled in magnetic fields lower than 30 μT or environmental magnetic field was changed to 1-2 μT.
2. In order to reduce environmental magnetic field noises, we investigated various techniques of active compensation that is combined with a soft-shielding simple MSR composed 1-2 layers of μ-metal. A novel compensation method was implemented in which a noise-field detection coil was wound around the MSR wall and a Helmholz-type compensation coil was also wound around the MSR. As a method than is useful in multichannel system, a feedback flux in a flux-locked-loop operation of a magnetometer that detects exclusively field noises was supplied to the feedback coil of other signal-sensing magnetometers. Using such compensation techniques with the soft-shielding MSR, 50-60 dB attenuation of the field noise was possible.
3. A multichannel magnetometer system for the measurement of magnetocardiographic signal (MCG) was constructed. The system was installed within the above MSR implemented with the active noise compensation. Real-time MCG signals were measured from the human heart of normal subjects in a wide band-width of 1-100 Hz.

Report

(4 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (83 results)

All Other

All Publications (83 results)

  • [Publications] K.Yokosawa: "Axial high-temperature superconducting-quantum-interference-device gradiometer composed of magnetometers with a monolithic feedback and compensation coil"Applied Physics Letters. 78. 2745-2747 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Hirano: "Direct detection of the magnetic flux noise from moving vortices in wide YBa_2Cu_3O_<7-δ> grain boundary junctions"Applied Physics Letters. 78. 1715-1717 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] K.Yokosawa: "Mechanisms of noise increase in direct-coupled high T_c super conducting quantum interference device magnetometers exposed to magnetic fields"Journal of Applied Physics. 90. 4049-4055 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Hirano: "Direct detection of vortex motion in high-Tc grain boundary junctions"IEEE Transactions on Applied Superconductivity. 11. 924-927 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M.Matuda: "High-Tc SQUID magnetometers for use in moderate magnetically-shielded room"IEEE Transactions on Applied Superconductivity. 11. 1323-1326 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Y.Yokosawa: "Effect of a static magnetic field on a slotted high-Tc SQUID magnetometer without flux dam"IEEE Transactions on Applied Superconductivity. 11. 1335-1338 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H.Oyama: "Suppression of field-induced low frequency noise in high Tc-SQUID magnetometers using slotted flux dams"Physica C. 357-360. 1451-1454 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Hirano: "Direct flux noise measurement of YBCO grain boundary junctions"Physica C. 375-360. 1455-1458 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H.Oyama: "Low-frequency noise of dc SQUID magnetometers having slotted structure along grain boundary junction"Superconducting Science and Technology. 15. 1-4 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 林 周: "生体磁気計測のための低磁場空間の生成"電気学会論文誌. 121-C(11). 1704-1710 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 藤田 学: "小動物心磁図計測用高温超電導SQUID磁束計の開発"電気学会論文誌. 121-C(11). 1104-1109 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 竹内 文也: "脳深部に巨大電流双極子を局在させる脳磁界応答の解析"医用電子と生体工学. 39. 189-196 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Kuriki: "Active compensation in combination with weak passive shielding for magnetocardiogrophic measurements"Review of Scientific Instruments. 73. 440-445 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Kuriki: "Development of a high-Tc SQUID-based magnetometer system for MCG measurement"ICICE Transactions on Electronics. E85-C(3). 670-676 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M.Matsuda: "First derivative high-Tc SQUID gradiometers with narrow structure from single layer YBCO thin film"ICICE Transactions on Electronics. E85-C(3). 677-680 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Kuriki: "Hight-Tc SQUID magnetometer system with active cancellation"Advances in Cryogenics. 47-48(to be published). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S.Oyu: "Use of ventricular excitation model in the magnetocardiographic inverse problem for reconstruction of electrophysiological properties"IEEE Transactions on Biomedical Engineering. (to be published). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 栗城 眞也: "超伝導生体工学"応用物理. 71. 23-28 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 鷲尾知暁: "磁場雑音打消し法の検討-心磁図計測のためのアクティブキャンセレーション-"電子情報通信学会技術研究報告. MBE2001-82. 81-87 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] K. Yokosawa: "Axial high- temperature superconducting-quantum-interference-device gradiometer composed of magnetometers with a monolithic feedback and compensation coil"Applied Physics Letters. 78. 2745-2747 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Hirano: "Direct detection of the magnetic flux noise from moving vortices in wide YBa_2Cu_3O_7 grain boundary junctions"Applied Physics letters. 78. 1715-1717 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] K. Yokosawa: "Mechanisms of noise increase in direct-coupled high T_c super- conducting quantum interference device magnetometers exposed to magnetic fields"Journal of Applied Physics. 90. 4049-4055 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Hirano: "Direct detection of vortex motion in high-Tc grain boundary junctions"IEEE Transactions on Applied Superconductivity. 11. 924-927 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M. Matuda: "High-TcSQUID magnetometers for use in moderate magnetically-shielded room"IEEE Transactions on Applied Superconductivity. 11. 1323-1326 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Y. Yokosawa: "Effect of a static magnetic field on a slotted high-Tc SQUID magnetometer without flux"IEEE Transactions on Applied Superconductivity. 11. 1335-1338 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Oyama: "Suppression of field-induced low frequency noise in high Tc-SQUID magnetometers using slotted flux dams"Physica C.. 357-360. 1451-1454 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Hirano: "Direct flux noise measurement of YBCO grain boundary junctions"Physica C.. 357-360. 1455-1458 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] H. Oyama: "Low-frequency noise of dc SQUID magnetometers having slotted structure along grain boundary junction"Superconducting Science and Technology. 15. 1-4 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Kuriki: "Active compensation in combination with weak passive shielding for magnetocardiographic measurements"Review of Scientific Instruments. 73. 440-445 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Kuriki: "Development of a high-Tc SQUID-based magnetometer system for MCG measurement"ICICE Transactions on Electronics. E85-C(3). 670-676 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] M. Matsuda: "First derivative high-Tc SQUID gradiometers with narrow structure from single layer YBCO thin film"ICICE Transactions on Electronics. E85-C(3). 677-680 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Kuriki: "Hight-Tc SQUID magnetometer system with active cancellation"Advances in Cryogenics. 47-48 (to be published). (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] S. Oyu: "Use of ventricular excitation model in the magnetocardiographic inverse problem for reconstruction of electrophysiological properties"IEEE Transactions on Biomedical Engineering. (to be published). (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] K. Yokosawa: "Axial high-temperature superconducting-quantum-interference-device gradiometer composed of magnetometers with a monolithic feedback and compensation coil"Applied Physics Letters. 78. 2745-2747 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] S. Hirano: "Direct detection of the magnetic flux noise from moving vortices in wide YBa_2Cu_3O_<7-δ> grain boundary junctions"Applied Physics Letters. 78. 1715-1717 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] K. Yokosawa: "Mechanisms of noise increase in direct-coupled high Tc super-conducting quantum interference device magnetometers exposed to magnetic fields"Journal of Applied Physics. 90. 4049-4055 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] S. Hirano: "Direct detection of vortex motion in high-Tc grain boundary junctions"IEEE Transactions on Applied Superconductivity. 11. 924-927 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] M. Matuda: "High-Tc SQUID magnetometers for use in moderate magnetically-shielded room"IEEE Transactions on Applied Superconductivity. 11. 1323-1326 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Y. Yokosawa: "Effect of a static magnetic field on a slotted high-Tc SQUID magnetometer without flux dam"IEEE Transactions on Applied Superconductivity. 11. 1335-1338 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] H. Oyama: "Suppression of field-induced low frequency noise in high Tc-SQUID magnetometers using slotted flux dams"Physica C. 357-360. 1451-1454 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] S. Hirano: "Direct flux noise measurement of YBCO grain boundary junctions"Physica C. 375-360. 1455-1458 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] H. Oyama: "Low-frequency noise of dc SQUID magnetometers having slotted structure along grain boundary junction"Superconducting Science and Technology. 15. 1-4 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 林 周: "生体磁気計測のための低磁場空間の生成"電気学会論文誌. 121-C(11). 1704-1710 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 藤田 学: "小動物心磁図計測用高温超電導SQUID磁束計の開発"電気学会論文誌. 121-C(11). 1104-1109 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 竹内 文也: "脳深部に巨大電流双極子を局在させる脳磁界応答の解析"医用電子と生体工学. 39. 189-196 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] S. Kuriki: "Active compensation in combination with weak passive shielding for magnetocardiographic measurements"Review of Scientific Instruments. 73. 440-445 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] S. Kuriki: "Development of a high-Tc SQUID-based magnetometer system for MCG measurement"ICICE Transactions on Electronics. E85-C(3). 670-676 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] M. Matsuda: "First derivative high-Tc SQUID gradiometers with narrow structure from single layer YBCO thin film"ICICE Transactions on Electronics. E85-C(3). 677-680 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] S. Kuriki: "High-Tc SQUID magnetometer system with active cancellation"Advances in Cryogenics. 47-48(to be published). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] S. Oyu: "Use of ventricular excitation model in the magnetocardiographic inverse problem for reconstruction of electrophysiological properties"IEEE Transactions on Biomedical Engineering. (to be published). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 栗城 眞也: "超伝導生体工学"応用物理. 71. 23-28 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 鷲尾知暁: "磁場雑音打消し法の検討-心磁図計測のためのアクティブキャンセレーション-"電子情報通信学会技術研究報告. MBE2001-82. 81-87 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 小池佑辰: ""簡易磁気シールド環境下の生体磁気計測におけるオフライン処理による商用電源ノイズ低減の検討""日本応用磁気学会誌. Vol.4(3). 141-145 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 小山洋: ""磁場中における高温超伝導SQUID磁束計の動作特性""電子情報通信学会論文誌. Vol.J83-C. 860-866 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 栗城眞也: ""SQUIDの生体磁気計測への応用""電気学会誌. Vol.120. 219-222 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 栗城眞也: ""生体磁気計測における低磁場雑音空間の生成技術""電磁環境工学情報EMC. No.147. 28-33 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] K.Yokosawa: ""Evaluating the entry of vortices into a slotted high-Tc SQUID magnetometer with a double-pickup-coil configuration""Physica C. Vol.341-348. 2705-2706 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] H.Oyama: ""High-Tc SQUID magnetometers with mesh structure""Advances in Superconductivity. Vol.12. 1027-1029 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] S.Hirano: ""Direct flux noise measurement of YBa_2Cu_3O_<7-δ> grain boundary junction""Advances in Superconductivity. Vol.12. 1039-1041 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 林周: ""生体計測のための環境磁場雑音の打ち消し方の検討""電子情報通信学会技術研究報告. MBE2000-36. 51-57 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 小山洋: ""高温超伝導SQUID磁束計の磁場中動作特性""電子情報通信学会技術研究報告. SCE2000-13. 15-20 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 平野悟: ""YBCO薄膜粒界接合の磁束ノイズ特性""電子情報通信学会技術研究報告. SCE2000-14. 21-28 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] F.Takeuchi: ""Multidipole analysis using a modified parameter search method""Proc.12th International Conference on Biomagnetism. (in printing). (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] S.Kuriki: ""Hybrid technique for reduction of environmental magnetic field noise""Proc.12th International Conference on Biomagnetism. (in printing). (2001)

    • Related Report
      2000 Annual Research Report
  • [Publications] S.Hirano: ""Direct detection of vortex motion in high-Tc grain boundary junctions""IEEE Trans.Appl.Supercond. (in printing).

    • Related Report
      2000 Annual Research Report
  • [Publications] H.Oyama: ""Effect of flux dam on the low frequency noise in high-Tc SQUID magnetometer""IEEE Trans.Appl.Supercond.. (in printing).

    • Related Report
      2000 Annual Research Report
  • [Publications] K.Yokosawa: ""Effect of a static magnetic field on a slotted high-Tc SQUID magnetometer without flux dam""IEEE Trans.Appl.Supercond.. (in printing).

    • Related Report
      2000 Annual Research Report
  • [Publications] M.Mastuda: ""High-Tc SQUID magnetometers for use in moderate magnetically-shielded room""IEEE Trans.Appl.Supercond.. (in printing).

    • Related Report
      2000 Annual Research Report
  • [Publications] S. Kuriki: "On the ac bias readout scheme for high-Tc superconducting quantum interference devices"Jpn. J. Appl. Phys.. 38. 4733-4736 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] S. Kuriki: "Transmission line high-Tc dc-SQUIDs"IEEE Trans. Appl. Supercond.. 9. 3275-3278 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 小池 佑辰: "簡易磁気シールド環境下の生体磁気計測におけるオフライン処理による商用電源ノイズ低減の検討"日本応用磁気学会誌. 24. 141-145 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] T. Kobayashi: "Principal component elimination method for the improvement of S/N in evoked neuromagnetic field measurements"IEEE Trans. Biomed. Eng.. 46. 951-958 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] K. Yokosawa: "Fabrication of high-Tc SQUID magnetometer with double-pickup-coil configuration"Advances in Superconductivity. XI. 1225-1228 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] M. Matsuda: "High-Tc SQUIDs on bicrystal substrate with low permittivity"Ext. Abst. Int. Supercond. Elect. Conf.. 137-139 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] S. Ohyu: "Three-dimensional distribution of ventricular action potential amplitude estimated from magnetocardiogram"Recend Advances in Biomagnetism (Tohoku Univ. Press). 632-635 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 平野 悟: "超伝導薄膜デバイスの磁束ノイズ測定"電子情報通信学会技術研究報告. SCE99-19. 31-36 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 林 周: "高温超伝導SQUIDのためのacバイアス駆動方式に関する検討"電子情報通信学会技術研究報告. SCE99-20. 37-42 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 平野 悟: "高温超伝導YBa_2Cu_3O_<7-δ>薄膜粒界接合における磁束量子運動"電子情報通信学会技術研究報告. SCE99-21. 1-6 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 小山 洋: "磁場中における高温超伝導SQUID磁束計の動作特性"電子情報通信学会技術研究報告. SCE99-22. 7-12 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 小池 佑辰: "生体磁気計測におけるオフライン処理によるノイズ低減の検討"電気学会マグネティックス研究会資料. MAG99-131. 97-102 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 林 周: "アクティブシールドを用いた低磁場空間の生成"電気学会マグネティックス研究会資料. MAG99-132. 103-108 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] H. Oyama: "High-Tc dc-SQUID Magnetometers with Mesh Structure"Abst. 12th Int. Symp. Supercond. 64 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] S.Hirano: "Direct flux noise measurement ob YBa_2Cu_3O_<7-d> grain boundary junction"Abst. 12th Int. Symp. Supercond.

    • Related Report
      1999 Annual Research Report

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Published: 1999-04-01   Modified: 2016-04-21  

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