• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Evaluations of Specific Endothelial Cell Markers in Lung Alveolar Capillaries

Research Project

Project/Area Number 11470143
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Respiratory organ internal medicine
Research InstitutionNippon Medical School

Principal Investigator

KAWANAMI Oichi  Nippon Medical School, Institute of Gerontology, Professor, 老人病研究所, 教授 (70096973)

Co-Investigator(Kenkyū-buntansha) FUJIWARA Masakazu  Nippon Medical School, Institute of Gerontology, Lecturer, 老人病研究所, 助手 (20312069)
JIN Enjing  Nippon Medical School, Institute of Gerontology, Lecturer, 老人病研究所, 助手 (10312068)
GHAZIZADEH Mohammad  Nippon Medical School, Institute of Gerontology, Associate Professor, 老人病研究所, 助教授 (30190979)
EMI Mitsuru  Nippon Medical School, Institute of Gerontology, Professor, 老人病研究所, 教授 (90221118)
OHTA Shigeo  Nippon Medical School, Institute of Gerontology, Professor, 老人病研究所, 教授 (00125832)
大國 寿士  日本医科大学, 老人病研究所, 教授 (60060365)
Project Period (FY) 1999 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥14,600,000 (Direct Cost: ¥14,600,000)
Fiscal Year 2001: ¥3,500,000 (Direct Cost: ¥3,500,000)
Fiscal Year 2000: ¥4,200,000 (Direct Cost: ¥4,200,000)
Fiscal Year 1999: ¥6,900,000 (Direct Cost: ¥6,900,000)
Keywordsalveolar capillary / vascular endothelial cell / protease-activated receptor / thrombomodulin / thrombin / lung adenocarcinoma / lung injury / serine protease / VEGF / KDR / Flt / laser capture microdissection / confocal laser scanning microscope / RT-PCR / 肺微小血管 / 気管支動脈 / 肺動脈 / 内皮細胞 / 凝固因子 / 抗凝固因子 / マトリジェル
Research Abstract

Morphology of the alveolar capillaries in the lung has been well documented under healthy and pathologic conditions. However, so-far available results could be summarized as plain observations by light and electron microscopies, and the functional implication derived from them is far from satisfactory. In order to explain and evaluate phenotypic activation of alveolar capillary endothelial cells, our observation has been focusing on a single unit capillary of alveolar walls in the lung. Together with electron and confocal laser scanning microscopies, multiple probing antigens, including anticoagulant thrombomodulin (TM), coagulant von Willebrand factor (vWf), protease-activated receptors (PAR) and their ligand-serine proteases, have been applied on human and experimental animal lungs. Important and novel findings we have obtained were as follows : 1) alveolar capillary endothelium lacked a conventional expression of vWf, but fully covered by TM ; 2) immunohistochemical conversion, from TM- to vWf-dominant phenotype, underwent when alveolar walls were damaged or metastasized by neoplastic cells of primary lung adenocarcinoma ; 3) PAR in endothelial cells elicited by nearby neoplastic cells facilitated a loss of TM while vWf started to accumulate ; and 4) activation of PAR on endothelial cells by serine proteases such as thrombin lead to exert a variety of biological activities, including cell growth and collagen production in alveolar wall cells. Thus, alveolar capillary endothelial cells might at least partly be a primary stimulator for repairing alveolar damages. In this connection alveolar capillary endothelial cells would be deeply involved in promoting cellular network functions among the alveolar wall cells. Our research aims are forwarding further to evaluate basic functions of endothelial cells in collagen vascular disease-related lung fibrosis.

Report

(4 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (64 results)

All Other

All Publications (64 results)

  • [Publications] Liu A M, Ghazizadeh M, Onouchi Z, Asano G.: "Ultrastructutral characteristics of myocardial and coronary microvascular lesions in Kawasaki disease"Microvasc.Res.. 58・. 10-27 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 川並汪一, 金恩京: "間質性肺炎と肺微小血管内皮細胞:障害と修復に対する領域別の特性"Molecular Medicine. 36・. 74-85 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 榎本達治, 川並汪一, 工藤翔二, 佐藤雅史, 中田紘一郎, 他: "ランゲルハンス細胞性肉芽腫症の気管支肺胞洗浄液中に出現する特異な組織球"呼吸. 18・. 528-536 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kawanami O, Jin E, Ghazizadeh M, Fujiwara M, Jiang L, et al.: "Mosaic-like distribution of endothelial cell antigens in capillaries and juxtaalveolar microvessels in the normal human lung"Pathol.Int.. 50・2. 136-141 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kawanami O, Jin E, Ghazizadeh M, Fujiwara M, Jiang L, et al.: "Heteregeneous distribution of thrombomodulin and von Willebrand factor in endothelial cells in the human pulmonary microvessels"J.Nippon Med.Sch.. 67・2. 118-125 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Jin E, Kawanami O.: "Unique distribution of von Willebrand factor and thrombomodulin in endothelial cells of human pulmonary microvessels"J.Nippon Med.Sch.. 67・2. 64-65 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Jin E, Ghazizadeh M, Fujiwara M, I Nagashima M, Kawanami O, et al.: "Angiogenesis and phenotypic alteration of alveolar capillary endothelium in areas of neoplastic cell spread in primary lung adenocarcinoma"Pathol.Int.. 51・9. 691-700 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Takahashi T, Azuma A, Abe S, Kawanami O, Ohara K, Kudoh: "Significance of lymphocytosis in bronchoalveolar lavage in suspected ocular sarcoidosis"Eur.Respir.J.. 18・3. 515-521 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Jin E, Fujiwara M, Nagashima M, Shimizu H, Kawanami O, et al.: "Aerogenous spread of primary lung adenocarcinoma induces ultrastructural remodeling of the alveolar capillary endothelium"Hum.Pathol.. 32・10. 1050-1058 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamano G, Funahashi H, Kawanami O, Zhao LX, Ban N, Uchida Y, et al.: "ABCA3 is a lamellar body membrane protein in human lung alveolar typeII cells(1)"FEBS Lett.. 16・508. 221-225 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Obara K, Ghazizadeh M, Shimizu H, Arai R, Tenjin T, Kawanami O, et al.: "Comprative genomic hybridization study of genetic changes associated with vindesine resistance in esophageal carcinoma"Int.J.Oncology.20(2):255-260.2002 Feb.. 20・2. 255-260 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Fujiwara M, Jin E, Ghazizadeh M, Kawanami O: "Antisense oligodeoxynucleotides against thrombomodulin suppress the cell growth of lung adenocarcinoma cell line A549 cells"Pathol.Int.52:204-213.2002 Apr.. 52・20. 204-213 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Shen G H, Ghazizadeh M, Kawanami O, Kurihara Y, Ghazizadeh M, et al.: "Propostic significance of vascular endothelial growth factor expression in human ovarian carcinoma"Brit.J.Cancer 83(2):196-2O3.2000 July.. 83・2. 196-203 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Arai, R, Ghazizadeh M, Kawanami O: "Comparative genomic hybridization analysis of cisplatin-resistant ovarian carcinoma cells"J.Nippon Med.Sch.. 67・. 416-417 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Fujiwara M, Jin E, Ghazizadeh M, Kawanami O.: "An in vitro model to evaluate regulatory mechanisms of antigen expression by normal pulmonary vessel endothelial cells"Microvasc.Res.. 61・2. 215-219 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Imai J, Ghazizadeh M, Naito Z, Asano G.: "Immunohistochemical expression of T, Tn and sialyl-Tn antigens and clinical outcome in human breast carcinoma"Anticancer Res.. 21・2B. 1327-1334 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Ozaki N, Ishizaki M, Ghazizadeh M, Yamanaka N.: "Apoptosis mediates decrease in cellularity during the regression of Arthus reaction in cornea"Br.J.Ophthalmol.. 85・5. 613-618 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yoshimura C, Miyamasu M, Nagase H, Iikura M, Kawanami O, et al.: "Morita Y, Iwata T, Yamamoto K, Hirai K.: Glucocorticoids induce basophil apoptosis"J.Allergy Clin.Immunol.. 108・2. 215-220 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kurihara Y, Ghazizadeh M, Bo H, Shimizu H, Kawanami O, et al.: "Genome-wide screening of laser capture microdissected gastric signet-ring cell carcinomas"J.Nippon Med.Sch.. (In press). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Jin E, Fujiwara M, Ghazizadeh M, Takemura T, Kawanami O: "Protease-activated receptors participate alveolar capillary angiogenesis in lung adenocarcinoma"(submitted). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Liu A M, Ghazizadeh M, Onouchi Z, Asano G.: "Ultrastructural characteristics of myocardial and coronary microvascular lesions in Kawasaki disease"Microvasc. Res.. 58. 10-27 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kawanami O, Jin E, Ghazizadeh M, Fujiwara M, Jiang L, Ohaki Y, Gomibuchi M, Takemura T.: "Mosaic-like distribution of endothelial cell antigens in capillaries and juxtaalveolar microvessels in the normal human lung"Pathol. Int.. 50(2). 136-141 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kawanami O, Jin E, Ghazizadeh M, Fujiwara M, Jiang L, Takemura T, Ohaki Y, Gomibuchi M, Arai S, Takeda K, Yu ZX, Ferrans V J.: "Heteregeneous distribution of thrombomodulin and von Willebrand factor in endothelial cells in the human pulmonary microvessels"J. Nippon Med.Sch.. 67(2). 118-125 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Jin E, Kawanami O.: "Unique distribution of von Willebrand factor and thrombomodulin in endothelial cells of human pulmonary microvessels"J. Nippon Med.Sch.. 67(2). 64-65 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Shen G H, Ghazizadeh M, Kawanami O, Shimizu H, Jin E, Araki T, Sugisaki Y.: "Prognostic significance of vascular endothelial growth factor expression in human ovarian carcinoma"Brit. J. Cancer. 83(2). 196-203 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Arai, R, Ghazizadeh, M, Kawanami O.: "Comparative genomic hybridization analysis of cisplatin- resistant ovarian carcinoma cells"J. Nippon Med.Sch.. 67. 416-417 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Fujiwara M, Jin E, Ghazizadeh M, Kawanami O.: "An in vitro model to evaluate regulatory mechanisms of antigen expression by normal pulmonary vessel endothelial cells"Microvasc. Res.. 61(2). 215-219 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Imai J, Ghazizadeh M, Naito Z, Asano G.: "Immunohistochemical expression of T, Tn and sialyl-Tn antigens and clinical outcome in human breast carcinoma"Anticancer Res.. 21(2B). 1327-1334 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Ozaki N, Ishizaki M, Ghazizadeh M, Yamanaka N.: "Apoptosis mediates decrease in cellularity during the regression of Arthus reaction in cornea"Br. J. Ophthalmol.. 85(5). 613-618 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yoshimura C, Miyamasu M, Nagase H, Iikura M, Yamaguchi M, Kawanami O, Morita Y, Iwata T, Yamamoto K, Hirai K.: "Glucocorticoids induce basophil apoptosis"J. Allergy Clin. Immunol.. 108(2). 215-220 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Jin E, Ghazizadeh M, Fujiwara M, Nagashima M, Shimizu H, Ohaki Y, Arai S, Gomibuchi M, Takemura T, Kawanami O.: "Angiogenesis and phenotypic alteration of alveolar capillary endothelium in areas of neoplastic cell spread in primary lung adenocarcinoma"Pathol. Int.. 15(9). 691-700 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Takahashi T, Azuma A, Abe S, Kawanami O, Ohara K, Kudoh.: "Significance of lymphocytosis in bronchoalveolar lavage in suspected ocular sarcoidosis"Eur. Respir. J.. 18(3). 515-521 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Jin E, Fujiwara M, Nagashima M, Shimizu H, Ghazizadeh M, Pan X, Arai S, Ohaki Y, Gomibuchi M, Takemura T, Kawanami O.: "Aerogenous spread of primary lung adenocarcinoma induces ultrastructural remodeling of the alveolar capillary endothelium"Hum. Pathol.. 32(10). 1050-1058 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamano G, Funahashi H, Kawanami O, Zhao LX, Ban N, Uchida Y, Morohoshi T, Ogawa J, Shioda S, Inagaki N.: "ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells(1)"FEBS Lett.. 16 ; 508(2). 221-5 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Obara K, Ghazizadeh M, Shimizu H, Arai R, Tenjin T, Suzuki S, Moriyama Y, Kawanami O.: "Comparative genomic hybridization study of genetic changes associated with vindesine resistance in esophageal carcinoma"Int. J. Oncology. 20(2). 255-260 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Fujiwara M, Jin E, Ghazizadeh M, Kawanami O.: "Antisense oligodeoxynucleotides against thrombomodulin suppress the cell growth of lung adenocarcinoma cell line A549 cells"Pathol. Int.. 52. 204-213 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Kurihara Y, Ghazizadeh M, Bo H, Shimizu H, Kawanami O, Moriyama Y, Onda M.: "Genome-wide screening of laser capture microdissected gastric signet-ring cell carcinomas"J. Nippon Med. Sch.. (in press). (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Jin E, Fujiwara M, Ghazizadeh M, Takemura T, Kawanami O.: "Protease-activated receptors participate alveolar capillary angiogenesis in lung adenocarcinoma"(submitted). (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Fujiwara M., Jin E. et al.: "An in vitro model to evaluate regulatory mechanisms of antigen expression by normal pulmonary vessel endothelial cells"Microvasc Res.. 61・2. 215-219 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Jin E., Fujiwara M., Nagashima M., Shimizu H., Ghazizadeh M. et al.: "Aerogenous spread of primary lung adenocarcinoma induces ultrastructural remodeling of the alveolar capillary endothelium"Human Pathology. 32・10. 1050-1058 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Jin E., Ghazizadeh M., Fujiwara M., Nagashima M. et al.: "Angrogenesis and phenotypic alteration of alveolar capillary endothelium in areas of neoplastic cell spread in primary lung adenocarcinoma"Pathology International. 51・9. 691-700 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 川並汪一, 持丸 博, 新井 悟: "シリカの経気道投与による肺胞とその毛細血管のリモデリング"エアロゾル研究. 16・4. 285-288 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Yamano G., Funahashi H., Kawanami O. et al.: "ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells(1)"FEBS Lett.. 16・508. 221-225 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 金 恩京, 川並汪一: "気道と肺の微小血管内皮細胞"細胞. 33・4. 136-140 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] Kawanami O.,Jin E., et al: "Mosaic-like distribution of endothelial cell antigens in capillaries and juxta-alveolar microvessels in the normal human lung."Pathol Int. 50(2). 136-141 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kawanami O.,Jin E., et al: "Heterogeneous distribution of thrombomodulin and von Willebrand factor inendothelial cells in the human pulmonary microvessels."Nippon Med Sch. 67(2). 118-125 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Shen GH,Ghazizadeh M, et al: "Prognostic significance of vascular endothelial growth factor expression in human ovarian carcinoma."Br J Cancer. 83(2). 196-203 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Jin E.,Kawanami O.: "Unique distribution of von Willebrand factor and thrombomodulin in endothelial cells of human pulmonary microvessels."J Nippon Med Sch. 67(2). 64-65 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Arai R.,Ghazizadeh M. et al: "Comparative genomic hybridization analysis of cisplatin-resistant ovarian carcinoma cells."J.Nippon Med.Sch.. 67. 416-417 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Fujiwara M.,Jin,E., et al: "An In Vitro model to evaluate regulatory mechanisms of antigen expression by normal pulmonary vessel endothelial cells."Microvasc.Res.. (in press). (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] Ozaki N., Ishizaki M., et al: "Apoptosis mediates decrease in cellularity during the regression of Arthus reaction in cornea."Brit J Opthalmology. (in press). (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 川並汪一,武村民子: "気管支喘息における気道リモデリング、特集"気道リモデリングに関与する細胞と治療への展望""医薬ジャーナル社. 9 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 川並汪一: "樹状細胞と呼吸器疾患,特集"アレルギーにおける樹状細胞""医薬ジャーナル社. 8 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 川並汪一,佐藤雅史: "肺の組織診におけるBALの重要性,特集:肺病変の見方(肺の生検)"文光堂. 7 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 川並汪一: "樹状細胞 呼吸器の生物学Annual Review呼吸器"中外医学社. 7 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 川並汪一: "トロンボモジュリン Key Word 1999-2000呼吸器疾患,"先端医学社. 2 (1999)

    • Related Report
      2000 Annual Research Report
  • [Publications] Kishikawa T et al.: "Specific role of T and Tn tumor-associated antigens in adhesion between a breast carcinoma cell line and a normal human breast epithelial cell line."Jpn. J Cancer Res.. 90. 326-332 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Liu A M et al.: "Ultrastructutral characteristics of myocardial and coronary microvascular lesions in Kawasaki disease."Microvasc. Res.. 58. 10-27 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 川並汪一 他: "間質性肺炎と肺微小血管内皮細胞:障害と修復に対する領域別の特性"Molecular Medicine.. 36. 74-85 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Kawanami O et.al: "Mosaic-like distribution of endothelial cell antigens in capillaries and juxaalveolar microvessels in the normal human lung."Pathol Int.. 50. 136-141 (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Kawanami O et.al.: "Heteregeneous distribution of thrombomodulin and von Willebrand factor in endothelial cells in the human pulmonary microvessels."J. Nippon Med. Sch.. 67(印刷中). (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] Shen G H et al.: "Prognostic significance of vascular endothelial growth factor expression in human ovarian carcinoma."Brit. J. Cancer. (印刷中). (1999)

    • Related Report
      1999 Annual Research Report
  • [Publications] 川並汪一 他: "血管新生(呼吸器の立場から).分子呼吸器病"先端医学社. 3 (2000)

    • Related Report
      1999 Annual Research Report
  • [Publications] 川並汪一: "樹状細胞.Annual Review呼吸器"7 (2000)

    • Related Report
      1999 Annual Research Report

URL: 

Published: 1999-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi