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Early Signs of Austic Disorder and Acoustic Analysis of their Speech

Research Project

Project/Area Number 11470204
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Psychiatric science
Research InstitutionTokai University

Principal Investigator

YAMAZAKI Kosuke  Tokai University, Schol of Medicine, Professor, 医学部, 教授 (50147170)

Co-Investigator(Kenkyū-buntansha) 加藤 由起子  東海大学, 医学部, 助手 (60246105)
Project Period (FY) 1999 – 2001
Project Status Completed (Fiscal Year 2001)
Budget Amount *help
¥4,300,000 (Direct Cost: ¥4,300,000)
Fiscal Year 2001: ¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2000: ¥1,100,000 (Direct Cost: ¥1,100,000)
Fiscal Year 1999: ¥1,200,000 (Direct Cost: ¥1,200,000)
Keywordsautistic disorder / Asperger disorder / home-video recordings / early signs / acoustic analysis / vowels formant / speech identification experiment / supplement motor area / 注意欠陥 / 多動性障害 / 音声言語 / 語音識別 / 聴覚障害 / 言語発達 / 音声波形 / 言語音知覚 / 発達段階
Research Abstract

Two studies were carried out, one on the early signs of autistic disorders, and the other an acoustic analysis of their characteristic speech patterns.
Study 1 : The early signs of autistic disorders. Subjects : Comparative analysis was carried out on an autistic disorder group (13 cases), normal control group (8 cases), attention deficit/hyperactivity disorder group (4 cases), expressive developmental speech disorder group (4 cases), and 1 case of auditory deficiency. Method : Home video records taken between age 0〜2 were analyzed in terms of : (1) social interaction, (2) affect, (3) perception, (4) motor/muscle tonus, and (5) behavior. Results : Hypersensitive perceptive behavior to light and small moving objects noted from before 6 months of age were regarded as the early signs. The probability of disorders in social interaction and affect being early signs are high, but could not be confirmed in this study. Disabilities in coordinated movement, and motor/muscle tonus disorders requi … More re further evaluation in association with functional disorders of the CNS Behavior pertaining to social interaction and perception were most frequent before 12 months, which were believed to be integrated into persistent behavior after 13 months of age.
Study 2 : Acoustic study on speech Subjects and Method : 1) The speech of 24 healthy 2〜6 year-olds were analyzed by a speech analyzer for transition in f1 and f2 of the 5 vowels. 2) Speech recordings collected from 116 healthy 2〜6 year-olds were analyzed by age regarding development of the 5 vowels through construction of f1/f2 diagrams. 3) 20 cases of Asperger disorder were tested for their ability to identify and imitate a changing sequence of synthesized speech "saita-taita-aita". Results : 1) The 5 vowels were found to be undifferentiated between age 2〜4, becoming integrated at age 5. 2) Analysis of 33 healthy children indicated that in infancy, the emergent stage of articulation, f2 acquisition precedes the gradual differentiation of f1 into the respective vowels. 3)Asperger disorder was classifiable into 3 categories by rate of sound identification.
Summary : Characteristic perceptive behavior was extracted as the early signs of autistic disorder. Acoustic analysis of speech peculiar to autistic children point to the possibility of insufficient inhibitory action from the supplementary motor and elevated activation of the auditory association area during the stage of speech acquisition. Continuation of basic studies is necessary for contributing to the treatment and guidance of children with autistic disorders. Less

Report

(4 results)
  • 2001 Annual Research Report   Final Research Report Summary
  • 2000 Annual Research Report
  • 1999 Annual Research Report
  • Research Products

    (45 results)

All Other

All Publications (45 results)

  • [Publications] 山崎晃資: "自閉症-最近の考え方-"総合臨床. 48. 2237-2238 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "大学病院における児童精神科医療の現状と課題"精神医学. 41. 1262-1269 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "ADHD(注意欠陥多動性障害)"精神療法. 26. 227-237 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "認知障害を持つ子どもの理解-その1 発達障害と自閉症-"養護学校の教育と展開. 117号. 44-49 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "認知障害を持つ子どもの瑛解-その2 注意欠陥多動性障害(ADHP)の歴史-"養護学校の教育と展開. 118号. 43-47 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "児童期精神障害とその分類-ICD-10とDSM-IV-"小児科診療. 63. 1559-1566 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "認知障害を持つ子どもの理解-その3 注意欠陥多動性障害の症状と対応-"養護学校の教育と展望. 119号. 40-44 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "発達障害"臨床精神医学. 増刊号. 80-86 (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "Asperger syndrome"生体の科学. 52. 167 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "認知障害を持つ子どもの理解-その4 発達障害児への精神療法的アプローチ-"養護学校の教育と展望. 120号. 47-51 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "児童青年精神医学の最新のトピクッス"最新精神医学. 6. 215-226 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "薬物療法"精神科治療学. 16. 19-27 (2001)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "AD/HDの薬物療法-課題-"精神科治療学. 17. 179-188 (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "AD/HD(注意欠陥/多動性障害)"日本精神神経学雑誌. 104(印刷中). (2002)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 佐藤慎子・山崎晃資(訳): "MGH総合病院精神医学(分担:児童と青年の精神薬理学)"メディカル・サイエンス・インターナショナル(分担). 605(18) (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "臨床児童青年精神医学入門(改訂)"安田生命社会事業団. 222 (1999)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "KEY WORD・精神 第2版(分担:乳幼児精神医学)"先端医学社(分担). 229(2) (2000)

    • Description
      「研究成果報告書概要(和文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Autistic disorder: the latest view"Clinical All-round. 48(9). 2237-2238 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Child and adolescent psychiatry in university hospital in Japan: present situation and problems"Clinical Psychiary. 141(12). 1262-1269 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "History and concepts of attention deficit/hyperactivity disorder"Japanese Journal of Psychotherapy. 26(3). 227-237 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Understanding on children with cognitive disorders : Part 1 Developmental disorder and autistic disorder"Yogogakko no Kyouiku to Tenbo. 117. 44-49 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Understanding on children with cognitive disorders : Part 2 History of attention deficit/hyperactivity disorder"Yogogakko no Kyouiku to Tenbo. 118. 43-47 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Mental disorders of childhood and its classification ICD-19 and DSM-IV"Journal of Pediatric Practice. 63(10). 1559-1566 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Understanding on children with cognitive disorder: Part 3 Symptoms and treatment of attention dericit/hyperactivity disorder"Yogogakko no Kyouiku to Tenbo. 119. 40-44 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Developmental disorders"Japanese Journal of Clinical Psychiatry Supplement. 80-86 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Asperger syndrome"Seitai no Igaku. 52(2). 167 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Understanding on children with cognitive disorders : Part 4 Psychotherapeutic approaches to children with developmental disorders - Towards to constnicting the developmental psychotherapy"Yogogakko no Kyouiku to Tenbo. 120. 47-51 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Recent topics of child and adolescent psychiatry in Japan"Japanese Journal of Psychiatry. 6(3). 215-226 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Pyschophannacological treatment in childhood"Seishinka Chiryougaku. 16(Supplement). 19-27 (2001)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Pharmacotherapy of AD/HD problems awaiting solution"Japanese Journal of Psychiatric Treatment. 17(2). 179-188 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Attention deficit / hyperactivity disorder"Psychiaria et Neurologica Japonica. 104(1). 55-65 (2002)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Sato, S. & Yamazaki, K.(Translation): "Medical Science International, Tokyo"Psychopharmacology in Childhood and adolescence.(In : Massachusetts General Hospital Handbook of General Hospital Psychiatry, 4th Eddition). 423-440 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] Yamazaki, K.: "Yasuda Life Welfare Foundation, Tokyo"Clinical Guidebook of Child and Adolescent Psychiatry(Revised). (1999)

    • Description
      「研究成果報告書概要(欧文)」より
    • Related Report
      2001 Final Research Report Summary
  • [Publications] 山崎晃資: "薬物療法"精神科治療学. 16巻増刊号. 10-27 (2001)

    • Related Report
      2001 Annual Research Report
  • [Publications] 山崎晃資: "AD/HDの薬物療法-課題-"精神科治療学. 14巻2号. 179-185 (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 山崎晃資: "AD/HD(注意欠陥/多動性障害)"日本精神神経学雑誌. 104巻2号(印刷中). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 山崎晃資, 小石誠二: "臨床精神薬理ハンドブック (分担:自閉症、注意欠陥/多動性障害、チックの薬物療法)"医学書院(印刷中). (2002)

    • Related Report
      2001 Annual Research Report
  • [Publications] 山崎晃資: "ADHD(注意欠陥多動性障害)の概念"精神療法. 26・3. 227-237 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 山崎晃資: "認知障害を持つ子どもの理解-その2 注意欠陥多動性障害(ADHD)の歴史-"養護学校の教育と展開. 118号. 43-48 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 山崎晃資: "認知障害を持つ子どもの理解-その3 注意欠陥多動性障害の症状と対応-"養護学校の教育と展開. 119号. 40-44 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 山崎晃資: "児童期精神障害とその分類"小児科診療. 63・10. 1559-1566 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 山崎晃資: "発達障害"臨床精神医学. 2000年増刊号. 80-86 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 山崎晃資: "KEY WORD精神第2版(分担執筆)"先端医学社. 219 (2000)

    • Related Report
      2000 Annual Research Report
  • [Publications] 山崎晃資: "若年期の痴呆と精神遅滞"老年精神医学雑誌. 9.12. 1464-1471 (1998)

    • Related Report
      1999 Annual Research Report
  • [Publications] 山崎晃資: "自閉症:最近の考え方"総合臨床. 48.9. 2237-2238 (1999)

    • Related Report
      1999 Annual Research Report

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Published: 1999-04-01   Modified: 2016-04-21  

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