| Project/Area Number |
11470303
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| Research Category |
Grant-in-Aid for Scientific Research (B).
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KOMORI Hiromichi Tokyo Medical and Dental Univ., Graduate School, Lecturer, 大学院・医歯学総合研究科, 講師 (60262169)
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| Co-Investigator(Kenkyū-buntansha) |
SHINOMIYA Kenichi Tokyo Medical and Dental Univ., Graduate School, Professor, 大学院・医歯学総合研究科, 教授 (20111594)
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| Project Period (FY) |
1999 – 2000
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| Project Status |
Completed (Fiscal Year 2000)
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| Budget Amount *help |
¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2000: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Keywords | Spinal Cord Evoked Magnetic Fields / Superconducting Qantum Interference Device / Spinal Cord Evoked Potentials / Peripheral Nerve Evoked Magnetic Fields |
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| Research Abstract |
We recorded cervical spinal cord evoked magnetic fields(SCEFs)and evaluated the usefulness of the magnetic field measurement that has theoretical advantages of high spatial resolution and noninvasive technique compared with the electric potential measurement.
First, we measured conductive cervical spinal cord evoked magnetic fields following thoracic spinal cord stimulation in cats and successfully visualized propagation of spinal cord activities. The conduction velocities of SCEFs were equivalent to the conduction velocities of the epidual spinal cord evoked potentials(SCEPs), although conduction velocities of subcutaneous SCEPs were extremely fast compared with epidual SCEPs. It suggests that the magnetic field measurement is more reliable than subcutaneous electric potential measurement.
Furthermore, after spinal cord transection, we could detect the conduction block of spinal cord activities at the spinal cord transection site. It suggests that the magnetic field measurement may be useful for the evaluation of the spinal cord function.
In human, we could record SCEFs after lower thoracic spinal cord stimulation on patients after laminectomy. However, SCEFs of normal subjects were much weaker than SCEF of patients after laminectomy. In order to record human SCEFs, we need averaging of much more trials and time through more sophisticated system.
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